Definition Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome.
Accession NC_007794
Length 3,561,584

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The map label for this gene is hflB [C]

Identifier: 87198597

GI number: 87198597

Start: 619329

End: 621647

Strand: Direct

Name: hflB [C]

Synonym: Saro_0573

Alternate gene names: 87198597

Gene position: 619329-621647 (Clockwise)

Preceding gene: 87198596

Following gene: 87198599

Centisome position: 17.39

GC content: 68.35

Gene sequence:

>2319_bases
ATGGCAGATGCGGCAACCGAAGCCCGGACCGAGGGGCGCACCGTGCGCCTGCAGGTGGCGGGCGCCCGCCAGGAAGAAAG
CGGCCACGGCATCGCTCGCATCAGCCGGCATGTCATGTCGCAGCTCGGCGTGACCGAAGGCGACGTGATCGAGATCGTCG
GCAAGCGCGCCACCGCCGCGCGGGTCATCCAGCCCTATCCCGAGGACGAGGGCCTCGAACTCATTCGCCTCGACGGGCTC
CAGCGCGCCAACGCCGATGTCGGCTCGGGCGAGCATGTCGAAGTGCGCAAGATCGATTCGCGCCCCGCCCAGCGCGTCGT
CTTCGCGCCGGCGCAGAAGGACCTGCGCCTCCAGGGCCCGGCGGTTGCGCTCAAGCGCAATTTCGCGGGGCGCCCGCTGG
TCACCGGCGACCTCGTCGCGACGGCGGGGCAGCAGCAGGTCAACCGCACCGACATGCCGCCGCAACTGCGCCAGATGCTC
AATGCGCCGGCGTTTGCGCTCACCCAGATCCGCCTCACCGTCGTCTCGACCAGCCCCAAGGGCGTGGTCCACATCGACGA
GAACACCGAGGTCGAGTTGCGCCCCGAATACGAGGAGCCGCGCAGCTCGCGCGCCGACGTCAACTACGACGACGTTGGCG
GCATGGGCGATACCATCCGCCAGCTCCGCGAGATGGTCGAGCTGCCGCTGCGCTATCCCGAACTCTTCACCCGCCTCGGC
GTCGATCCGCCCAAGGGGGTGCTTCTCCATGGCCCGCCGGGCACCGGCAAGACCCGCCTCGCCCGCGCCGTCGCGAACGA
GAGCGACGCCTCGTTCTTCACCATCAACGGGCCCGAGATCATGGGCTCGGCCTATGGCGAGAGCGAGAAGCGCCTGCGCG
AGGTGTTCGAGGAGGCAACCGCCAACTCGCCGTCGATCATCTTCATCGACGAGATCGATTCGATCGCGCCCAAGCGCAGC
GAAGTTCACGGCGAGGCCGAGAAGCGCCTCGTCGCGCAGCTCCTCACGCTGATGGACGGCCTGCACAGCCGCTCGAACCT
GGTCGTCATCGCCGCCACCAACCGGCCCGACGCGATCGACGAGGCCTTGCGCCGTCCCGGTCGCTTCGACCGCGAGATCG
TCGTCGGCGTTCCGGACGAAAGCGGCCGGCGCGAGATCCTCGGCATCCACACCCGCGGGATGCCGCTGGCCGAGGATGTC
GACCTCCAGGAGCTTGCCCGCACCACGCACGGCTTCGTCGGCGCGGATCTTGCGGCTCTTGCCCGCGAAGCCGCGATCGA
GGCTGTCCGCCGCATCATGCCGCGGCTCGATTTCGAACAGCAGACCATTCCTCAGGACGTCCTCGACAGCCTGCGGGTGG
AACGCGACGATTTCCTCGAGGCACTGAAGCGCGTTCAGCCCTCGGCCATGCGCGAAGTCATGGTCCAGGCTCCGACCATC
GGCTGGGCCGACATCGGCGGTCTGGACGAAGCGCAGGAAAAGCTGCGCGAAGGCGTCGAGCTGCCGCTGAAGAACCCCGA
GGCCTTCCACCGCCTCGGCATCCGGCCGGCCAAGGGCTTCCTGCTCTATGGTCCGCCCGGCACCGGCAAGACCCTGCTGG
CCAAGGCCGTGGCGAAGGAGGCGGAAGCCAACTTCATCGCGATCAAGTCGTCCGACCTCCTGTCCAAGTGGTACGGGGAG
AGCGAACAGCAGATCGCGCGCCTCTTCGCCCGCGCCCGCCAGGTCGCGCCTTGCGTGGTATTCATCGACGAGATCGACAG
CCTCGTCCCCGCGCGCGGCAGCGGGCAGGGCGAACCCAACGTCACAGCGCGGGTGGTCAACACCATCCTTGCCGAGATGG
ACGGGCTGGAGGAACTGCAATCCGTCGTCCTGATCGGCGCGACCAACCGACCCAACCTCGTCGATCCTGCGCTGCTCCGT
CCGGGTCGTTTCGACGAACTGGTCTATGTCGGCACGCCGAGCATGTCCGGGCGCGAGCACATCCTGGGCATCCACACCCG
CAACATGCCGCTCGCCCCCGACGTGGACCTCGCCCTGGTCGCCCGCGCGACCGACCGCTTCACCGGCGCCGATCTCGAGG
ACGTGGTGCGCCGGGCGGGCCTGAACGCCATCCGTCGCGGCGGCGGCAACGTCGATCAGGTCAAAGCTTCCGACTTCGAC
GAAGCCCTCGAAGACTCGCGCGCCACGGTGACCGAGCAGATGGAGGAAGAGTACGGCCGGATGAAGGGCGAACTGAAGAA
GCGCGCGATGAACCCCGGTCCGCTCGGCTTCATCGTTCCCGGCATGGTCCAGCCGACGCGCGAATCGAAGCACGGCTGA

Upstream 100 bases:

>100_bases
CACCGGGCGGTTCGCAACCAACCTGCTTCTCCAGCGTTTGAAATCCCGCCCGCCGGTTCCCACATCGGTTCTTGTCGGCA
GTTCAAGGGGAAATTCACTC

Downstream 100 bases:

>100_bases
CGCCATGCGTTGCATTGTCGTTGCGAACCCGGCCACCCGGCCCGGTTCGCACCGACGCTCGCAACGACCAGTGCCTCAGT
CCTCGGCGCCCTCCAGCGCA

Product: AAA family ATPase, CDC48 subfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 771

Protein sequence:

>772_residues
MADAATEARTEGRTVRLQVAGARQEESGHGIARISRHVMSQLGVTEGDVIEIVGKRATAARVIQPYPEDEGLELIRLDGL
QRANADVGSGEHVEVRKIDSRPAQRVVFAPAQKDLRLQGPAVALKRNFAGRPLVTGDLVATAGQQQVNRTDMPPQLRQML
NAPAFALTQIRLTVVSTSPKGVVHIDENTEVELRPEYEEPRSSRADVNYDDVGGMGDTIRQLREMVELPLRYPELFTRLG
VDPPKGVLLHGPPGTGKTRLARAVANESDASFFTINGPEIMGSAYGESEKRLREVFEEATANSPSIIFIDEIDSIAPKRS
EVHGEAEKRLVAQLLTLMDGLHSRSNLVVIAATNRPDAIDEALRRPGRFDREIVVGVPDESGRREILGIHTRGMPLAEDV
DLQELARTTHGFVGADLAALAREAAIEAVRRIMPRLDFEQQTIPQDVLDSLRVERDDFLEALKRVQPSAMREVMVQAPTI
GWADIGGLDEAQEKLREGVELPLKNPEAFHRLGIRPAKGFLLYGPPGTGKTLLAKAVAKEAEANFIAIKSSDLLSKWYGE
SEQQIARLFARARQVAPCVVFIDEIDSLVPARGSGQGEPNVTARVVNTILAEMDGLEELQSVVLIGATNRPNLVDPALLR
PGRFDELVYVGTPSMSGREHILGIHTRNMPLAPDVDLALVARATDRFTGADLEDVVRRAGLNAIRRGGGNVDQVKASDFD
EALEDSRATVTEQMEEEYGRMKGELKKRAMNPGPLGFIVPGMVQPTRESKHG

Sequences:

>Translated_772_residues
MADAATEARTEGRTVRLQVAGARQEESGHGIARISRHVMSQLGVTEGDVIEIVGKRATAARVIQPYPEDEGLELIRLDGL
QRANADVGSGEHVEVRKIDSRPAQRVVFAPAQKDLRLQGPAVALKRNFAGRPLVTGDLVATAGQQQVNRTDMPPQLRQML
NAPAFALTQIRLTVVSTSPKGVVHIDENTEVELRPEYEEPRSSRADVNYDDVGGMGDTIRQLREMVELPLRYPELFTRLG
VDPPKGVLLHGPPGTGKTRLARAVANESDASFFTINGPEIMGSAYGESEKRLREVFEEATANSPSIIFIDEIDSIAPKRS
EVHGEAEKRLVAQLLTLMDGLHSRSNLVVIAATNRPDAIDEALRRPGRFDREIVVGVPDESGRREILGIHTRGMPLAEDV
DLQELARTTHGFVGADLAALAREAAIEAVRRIMPRLDFEQQTIPQDVLDSLRVERDDFLEALKRVQPSAMREVMVQAPTI
GWADIGGLDEAQEKLREGVELPLKNPEAFHRLGIRPAKGFLLYGPPGTGKTLLAKAVAKEAEANFIAIKSSDLLSKWYGE
SEQQIARLFARARQVAPCVVFIDEIDSLVPARGSGQGEPNVTARVVNTILAEMDGLEELQSVVLIGATNRPNLVDPALLR
PGRFDELVYVGTPSMSGREHILGIHTRNMPLAPDVDLALVARATDRFTGADLEDVVRRAGLNAIRRGGGNVDQVKASDFD
EALEDSRATVTEQMEEEYGRMKGELKKRAMNPGPLGFIVPGMVQPTRESKHG
>Mature_771_residues
ADAATEARTEGRTVRLQVAGARQEESGHGIARISRHVMSQLGVTEGDVIEIVGKRATAARVIQPYPEDEGLELIRLDGLQ
RANADVGSGEHVEVRKIDSRPAQRVVFAPAQKDLRLQGPAVALKRNFAGRPLVTGDLVATAGQQQVNRTDMPPQLRQMLN
APAFALTQIRLTVVSTSPKGVVHIDENTEVELRPEYEEPRSSRADVNYDDVGGMGDTIRQLREMVELPLRYPELFTRLGV
DPPKGVLLHGPPGTGKTRLARAVANESDASFFTINGPEIMGSAYGESEKRLREVFEEATANSPSIIFIDEIDSIAPKRSE
VHGEAEKRLVAQLLTLMDGLHSRSNLVVIAATNRPDAIDEALRRPGRFDREIVVGVPDESGRREILGIHTRGMPLAEDVD
LQELARTTHGFVGADLAALAREAAIEAVRRIMPRLDFEQQTIPQDVLDSLRVERDDFLEALKRVQPSAMREVMVQAPTIG
WADIGGLDEAQEKLREGVELPLKNPEAFHRLGIRPAKGFLLYGPPGTGKTLLAKAVAKEAEANFIAIKSSDLLSKWYGES
EQQIARLFARARQVAPCVVFIDEIDSLVPARGSGQGEPNVTARVVNTILAEMDGLEELQSVVLIGATNRPNLVDPALLRP
GRFDELVYVGTPSMSGREHILGIHTRNMPLAPDVDLALVARATDRFTGADLEDVVRRAGLNAIRRGGGNVDQVKASDFDE
ALEDSRATVTEQMEEEYGRMKGELKKRAMNPGPLGFIVPGMVQPTRESKHG

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family. CDC48 subfamily [H]

Homologues:

Organism=Homo sapiens, GI6005942, Length=703, Percent_Identity=46.0881934566145, Blast_Score=600, Evalue=1e-171,
Organism=Homo sapiens, GI157671927, Length=581, Percent_Identity=44.2340791738382, Blast_Score=495, Evalue=1e-140,
Organism=Homo sapiens, GI45643125, Length=600, Percent_Identity=42.8333333333333, Blast_Score=470, Evalue=1e-132,
Organism=Homo sapiens, GI45643123, Length=600, Percent_Identity=42.8333333333333, Blast_Score=470, Evalue=1e-132,
Organism=Homo sapiens, GI229577436, Length=544, Percent_Identity=41.7279411764706, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI4505725, Length=480, Percent_Identity=37.0833333333333, Blast_Score=276, Evalue=5e-74,
Organism=Homo sapiens, GI194018488, Length=499, Percent_Identity=35.2705410821643, Blast_Score=263, Evalue=5e-70,
Organism=Homo sapiens, GI153792536, Length=282, Percent_Identity=44.6808510638298, Blast_Score=242, Evalue=8e-64,
Organism=Homo sapiens, GI24497618, Length=281, Percent_Identity=44.8398576512456, Blast_Score=242, Evalue=9e-64,
Organism=Homo sapiens, GI195539395, Length=246, Percent_Identity=43.9024390243902, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI24430151, Length=226, Percent_Identity=46.4601769911504, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI4506209, Length=241, Percent_Identity=45.643153526971, Blast_Score=204, Evalue=3e-52,
Organism=Homo sapiens, GI24497435, Length=228, Percent_Identity=44.7368421052632, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI89064750, Length=243, Percent_Identity=43.6213991769547, Blast_Score=198, Evalue=2e-50,
Organism=Homo sapiens, GI5729991, Length=243, Percent_Identity=43.6213991769547, Blast_Score=198, Evalue=2e-50,
Organism=Homo sapiens, GI24430155, Length=243, Percent_Identity=43.6213991769547, Blast_Score=198, Evalue=2e-50,
Organism=Homo sapiens, GI21361144, Length=226, Percent_Identity=45.575221238938, Blast_Score=198, Evalue=2e-50,
Organism=Homo sapiens, GI156564401, Length=434, Percent_Identity=35.9447004608295, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI5901990, Length=258, Percent_Identity=43.4108527131783, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI300192933, Length=270, Percent_Identity=39.6296296296296, Blast_Score=182, Evalue=9e-46,
Organism=Homo sapiens, GI7019569, Length=278, Percent_Identity=35.6115107913669, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI7657689, Length=225, Percent_Identity=44.4444444444444, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI21327685, Length=225, Percent_Identity=44.4444444444444, Blast_Score=180, Evalue=5e-45,
Organism=Homo sapiens, GI14149767, Length=311, Percent_Identity=37.620578778135, Blast_Score=180, Evalue=5e-45,
Organism=Homo sapiens, GI62177112, Length=311, Percent_Identity=37.620578778135, Blast_Score=180, Evalue=5e-45,
Organism=Homo sapiens, GI4507173, Length=230, Percent_Identity=42.1739130434783, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI31377644, Length=232, Percent_Identity=42.6724137931034, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI17865802, Length=279, Percent_Identity=36.9175627240143, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI11875211, Length=266, Percent_Identity=39.8496240601504, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI40806170, Length=266, Percent_Identity=39.8496240601504, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI31742536, Length=296, Percent_Identity=35.472972972973, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI112789543, Length=296, Percent_Identity=35.472972972973, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI226371754, Length=278, Percent_Identity=36.6906474820144, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI310125282, Length=303, Percent_Identity=38.2838283828383, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI310125280, Length=247, Percent_Identity=41.7004048582996, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI64084766, Length=269, Percent_Identity=31.2267657992565, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI40806173, Length=138, Percent_Identity=43.4782608695652, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI116292174, Length=261, Percent_Identity=30.2681992337165, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI11321607, Length=150, Percent_Identity=34.6666666666667, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI261337161, Length=113, Percent_Identity=36.283185840708, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI1789568, Length=242, Percent_Identity=47.1074380165289, Blast_Score=218, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17532375, Length=696, Percent_Identity=45.4022988505747, Blast_Score=581, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI17531535, Length=694, Percent_Identity=44.6685878962536, Blast_Score=576, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI17537217, Length=612, Percent_Identity=39.2156862745098, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17508053, Length=521, Percent_Identity=34.1650671785029, Blast_Score=260, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI193206116, Length=286, Percent_Identity=42.3076923076923, Blast_Score=230, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI133931034, Length=286, Percent_Identity=42.3076923076923, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI193206114, Length=286, Percent_Identity=42.3076923076923, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI71987372, Length=237, Percent_Identity=44.3037974683544, Blast_Score=209, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI71987364, Length=237, Percent_Identity=44.3037974683544, Blast_Score=209, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17563248, Length=276, Percent_Identity=39.4927536231884, Blast_Score=202, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17563250, Length=235, Percent_Identity=45.1063829787234, Blast_Score=201, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI25144281, Length=228, Percent_Identity=44.7368421052632, Blast_Score=198, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17554786, Length=240, Percent_Identity=44.5833333333333, Blast_Score=198, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI25144278, Length=228, Percent_Identity=44.7368421052632, Blast_Score=198, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17562804, Length=470, Percent_Identity=31.2765957446809, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI25153574, Length=478, Percent_Identity=30.5439330543933, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17508701, Length=261, Percent_Identity=40.9961685823755, Blast_Score=196, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17505546, Length=239, Percent_Identity=41.8410041841004, Blast_Score=193, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17554784, Length=241, Percent_Identity=44.3983402489627, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI193209502, Length=239, Percent_Identity=40.1673640167364, Blast_Score=179, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI86561515, Length=238, Percent_Identity=39.4957983193277, Blast_Score=172, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI133901662, Length=407, Percent_Identity=33.9066339066339, Blast_Score=169, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI133901658, Length=408, Percent_Identity=33.8235294117647, Blast_Score=168, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI17554264, Length=210, Percent_Identity=43.8095238095238, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI25146157, Length=274, Percent_Identity=37.956204379562, Blast_Score=166, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI32563584, Length=290, Percent_Identity=38.9655172413793, Blast_Score=166, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17508421, Length=286, Percent_Identity=39.1608391608392, Blast_Score=165, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI71994521, Length=234, Percent_Identity=42.7350427350427, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI115534323, Length=233, Percent_Identity=40.343347639485, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17541224, Length=250, Percent_Identity=38.4, Blast_Score=156, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17541226, Length=250, Percent_Identity=38.4, Blast_Score=156, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17560432, Length=282, Percent_Identity=37.2340425531915, Blast_Score=150, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17533043, Length=158, Percent_Identity=33.5443037974684, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17570397, Length=99, Percent_Identity=41.4141414141414, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32566590, Length=99, Percent_Identity=41.4141414141414, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320077, Length=687, Percent_Identity=45.9970887918486, Blast_Score=592, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6323429, Length=566, Percent_Identity=44.1696113074205, Blast_Score=449, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6322994, Length=576, Percent_Identity=40.625, Blast_Score=430, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321709, Length=273, Percent_Identity=46.5201465201465, Blast_Score=244, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6324000, Length=523, Percent_Identity=31.5487571701721, Blast_Score=224, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6322651, Length=501, Percent_Identity=31.936127744511, Blast_Score=223, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6320197, Length=226, Percent_Identity=46.9026548672566, Blast_Score=210, Evalue=7e-55,
Organism=Saccharomyces cerevisiae, GI6321390, Length=240, Percent_Identity=44.5833333333333, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6322704, Length=268, Percent_Identity=41.044776119403, Blast_Score=202, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6320602, Length=282, Percent_Identity=41.8439716312057, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6324833, Length=227, Percent_Identity=46.2555066079295, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6324691, Length=272, Percent_Identity=39.7058823529412, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6325281, Length=269, Percent_Identity=39.7769516728625, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6325431, Length=246, Percent_Identity=38.2113821138211, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6319554, Length=422, Percent_Identity=33.8862559241706, Blast_Score=173, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6321465, Length=230, Percent_Identity=43.4782608695652, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323736, Length=249, Percent_Identity=39.7590361445783, Blast_Score=171, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6320854, Length=249, Percent_Identity=40.1606425702811, Blast_Score=170, Evalue=8e-43,
Organism=Saccharomyces cerevisiae, GI6325183, Length=282, Percent_Identity=37.2340425531915, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6320887, Length=312, Percent_Identity=33.0128205128205, Blast_Score=146, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI9755327, Length=218, Percent_Identity=27.0642201834862, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6320583, Length=147, Percent_Identity=31.2925170068027, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161076486, Length=709, Percent_Identity=44.7108603667137, Blast_Score=586, Evalue=1e-167,
Organism=Drosophila melanogaster, GI17137560, Length=723, Percent_Identity=44.3983402489627, Blast_Score=585, Evalue=1e-167,
Organism=Drosophila melanogaster, GI161076488, Length=679, Percent_Identity=45.8026509572901, Blast_Score=581, Evalue=1e-166,
Organism=Drosophila melanogaster, GI19921202, Length=637, Percent_Identity=32.3390894819466, Blast_Score=332, Evalue=4e-91,
Organism=Drosophila melanogaster, GI24656825, Length=517, Percent_Identity=32.3017408123791, Blast_Score=267, Evalue=2e-71,
Organism=Drosophila melanogaster, GI281365776, Length=295, Percent_Identity=45.7627118644068, Blast_Score=261, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24660075, Length=295, Percent_Identity=45.7627118644068, Blast_Score=261, Evalue=2e-69,
Organism=Drosophila melanogaster, GI45552965, Length=295, Percent_Identity=45.7627118644068, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24656820, Length=536, Percent_Identity=31.1567164179104, Blast_Score=260, Evalue=3e-69,
Organism=Drosophila melanogaster, GI281363136, Length=503, Percent_Identity=32.20675944334, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI78707192, Length=503, Percent_Identity=32.20675944334, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI21355121, Length=473, Percent_Identity=32.1353065539112, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24652279, Length=194, Percent_Identity=51.0309278350515, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24649446, Length=226, Percent_Identity=47.3451327433628, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI18860063, Length=243, Percent_Identity=45.2674897119342, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI17137738, Length=241, Percent_Identity=45.2282157676349, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24640100, Length=268, Percent_Identity=42.5373134328358, Blast_Score=206, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24658770, Length=261, Percent_Identity=44.8275862068966, Blast_Score=206, Evalue=6e-53,
Organism=Drosophila melanogaster, GI281361487, Length=270, Percent_Identity=41.1111111111111, Blast_Score=202, Evalue=9e-52,
Organism=Drosophila melanogaster, GI24663015, Length=334, Percent_Identity=35.3293413173653, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24651451, Length=227, Percent_Identity=44.9339207048458, Blast_Score=200, Evalue=4e-51,
Organism=Drosophila melanogaster, GI19920408, Length=228, Percent_Identity=44.7368421052632, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI17738151, Length=261, Percent_Identity=41.7624521072797, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI17864540, Length=460, Percent_Identity=32.8260869565217, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24644145, Length=294, Percent_Identity=37.7551020408163, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI18859657, Length=247, Percent_Identity=40.080971659919, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281360146, Length=295, Percent_Identity=36.271186440678, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281360138, Length=295, Percent_Identity=36.271186440678, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281360142, Length=295, Percent_Identity=36.271186440678, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21357333, Length=295, Percent_Identity=36.271186440678, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI28573010, Length=380, Percent_Identity=34.7368421052632, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281360136, Length=295, Percent_Identity=36.271186440678, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24644411, Length=295, Percent_Identity=36.271186440678, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281360144, Length=295, Percent_Identity=36.271186440678, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI281360140, Length=295, Percent_Identity=36.271186440678, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI28574878, Length=280, Percent_Identity=39.2857142857143, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24665814, Length=280, Percent_Identity=39.2857142857143, Blast_Score=173, Evalue=4e-43,
Organism=Drosophila melanogaster, GI20129423, Length=270, Percent_Identity=35.5555555555556, Blast_Score=173, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24639391, Length=233, Percent_Identity=41.6309012875536, Blast_Score=173, Evalue=4e-43,
Organism=Drosophila melanogaster, GI20129529, Length=282, Percent_Identity=36.8794326241135, Blast_Score=173, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24581396, Length=289, Percent_Identity=36.6782006920415, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI28571849, Length=269, Percent_Identity=41.635687732342, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI28571847, Length=269, Percent_Identity=41.635687732342, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24639486, Length=232, Percent_Identity=35.7758620689655, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI45554047, Length=164, Percent_Identity=37.8048780487805, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573181, Length=152, Percent_Identity=34.2105263157895, Blast_Score=90, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR003593
- InterPro:   IPR005938
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR003338
- InterPro:   IPR004201
- InterPro:   IPR015415 [H]

Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 84414; Mature: 84283

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MADAATEARTEGRTVRLQVAGARQEESGHGIARISRHVMSQLGVTEGDVIEIVGKRATAA
CCCCCHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHH
RVIQPYPEDEGLELIRLDGLQRANADVGSGEHVEVRKIDSRPAQRVVFAPAQKDLRLQGP
HHHCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCCEECCC
AVALKRNFAGRPLVTGDLVATAGQQQVNRTDMPPQLRQMLNAPAFALTQIRLTVVSTSPK
HHHHHCCCCCCCCCCCHHHHHCCHHHCCCCCCCHHHHHHHCCCHHEEEEEEEEEEECCCC
GVVHIDENTEVELRPEYEEPRSSRADVNYDDVGGMGDTIRQLREMVELPLRYPELFTRLG
CEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCC
VDPPKGVLLHGPPGTGKTRLARAVANESDASFFTINGPEIMGSAYGESEKRLREVFEEAT
CCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHHHCCCCCCHHHHHHHHHHHHC
ANSPSIIFIDEIDSIAPKRSEVHGEAEKRLVAQLLTLMDGLHSRSNLVVIAATNRPDAID
CCCCCEEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
EALRRPGRFDREIVVGVPDESGRREILGIHTRGMPLAEDVDLQELARTTHGFVGADLAAL
HHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHH
AREAAIEAVRRIMPRLDFEQQTIPQDVLDSLRVERDDFLEALKRVQPSAMREVMVQAPTI
HHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCC
GWADIGGLDEAQEKLREGVELPLKNPEAFHRLGIRPAKGFLLYGPPGTGKTLLAKAVAKE
CCHHCCCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHH
AEANFIAIKSSDLLSKWYGESEQQIARLFARARQVAPCVVFIDEIDSLVPARGSGQGEPN
CCCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCCCCCCCCC
VTARVVNTILAEMDGLEELQSVVLIGATNRPNLVDPALLRPGRFDELVYVGTPSMSGREH
HHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCCCHHHCCCCCCCCEEEEECCCCCCCCE
ILGIHTRNMPLAPDVDLALVARATDRFTGADLEDVVRRAGLNAIRRGGGNVDQVKASDFD
EEEEEECCCCCCCCCCHHHEEHHHCCCCCCCHHHHHHHHCHHHHHHCCCCCCCCCCCCHH
EALEDSRATVTEQMEEEYGRMKGELKKRAMNPGPLGFIVPGMVQPTRESKHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCHHCCCC
>Mature Secondary Structure 
ADAATEARTEGRTVRLQVAGARQEESGHGIARISRHVMSQLGVTEGDVIEIVGKRATAA
CCCCHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHH
RVIQPYPEDEGLELIRLDGLQRANADVGSGEHVEVRKIDSRPAQRVVFAPAQKDLRLQGP
HHHCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCCEECCC
AVALKRNFAGRPLVTGDLVATAGQQQVNRTDMPPQLRQMLNAPAFALTQIRLTVVSTSPK
HHHHHCCCCCCCCCCCHHHHHCCHHHCCCCCCCHHHHHHHCCCHHEEEEEEEEEEECCCC
GVVHIDENTEVELRPEYEEPRSSRADVNYDDVGGMGDTIRQLREMVELPLRYPELFTRLG
CEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCC
VDPPKGVLLHGPPGTGKTRLARAVANESDASFFTINGPEIMGSAYGESEKRLREVFEEAT
CCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHHHCCCCCCHHHHHHHHHHHHC
ANSPSIIFIDEIDSIAPKRSEVHGEAEKRLVAQLLTLMDGLHSRSNLVVIAATNRPDAID
CCCCCEEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
EALRRPGRFDREIVVGVPDESGRREILGIHTRGMPLAEDVDLQELARTTHGFVGADLAAL
HHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHH
AREAAIEAVRRIMPRLDFEQQTIPQDVLDSLRVERDDFLEALKRVQPSAMREVMVQAPTI
HHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCC
GWADIGGLDEAQEKLREGVELPLKNPEAFHRLGIRPAKGFLLYGPPGTGKTLLAKAVAKE
CCHHCCCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHH
AEANFIAIKSSDLLSKWYGESEQQIARLFARARQVAPCVVFIDEIDSLVPARGSGQGEPN
CCCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCCCCCCCCC
VTARVVNTILAEMDGLEELQSVVLIGATNRPNLVDPALLRPGRFDELVYVGTPSMSGREH
HHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCCCHHHCCCCCCCCEEEEECCCCCCCCE
ILGIHTRNMPLAPDVDLALVARATDRFTGADLEDVVRRAGLNAIRRGGGNVDQVKASDFD
EEEEEECCCCCCCCCCHHHEEHHHCCCCCCCHHHHHHHHCHHHHHHCCCCCCCCCCCCHH
EALEDSRATVTEQMEEEYGRMKGELKKRAMNPGPLGFIVPGMVQPTRESKHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]