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The map label for this gene is gluQ [H]

Identifier: 87198575

GI number: 87198575

Start: 602665

End: 603510

Strand: Direct

Name: gluQ [H]

Synonym: Saro_0551

Alternate gene names: 87198575

Gene position: 602665-603510 (Clockwise)

Preceding gene: 87198572

Following gene: 87198576

Centisome position: 16.92

GC content: 68.79

Gene sequence:

>846_bases
ATGACCGTCACCCGCTTCGCTCCCAGCCCCAACGGCCCGCTCCATCTGGGGCATGCATATTCCGCAATCGTCGCCCATGA
CCGTGCGAAGCGTGACAATGGCGAATTTCTGCTGCGCATCGAGGACATAGACGGGGCGCGCTCCCGCCCCGACCTGGCAG
ACGAATTTCGTGCCGACCTGCAATGGCTCCGCCTCGACTACCGCGAGGTTGCCCCCCAGTCCCAGCGCATCGCCTCCTAC
CGCACCGCCGCGAACGAGCTGCGGGCGATGGGCATCCTCTACCCTTGCACCTGCACCCGTGCCGAGATTGCCGCCGCCGC
CGTCGCGCAGGGCCCGGATGGCCCGCTCTATCCCGGCACCTGCCTGCGCCGCGGGCCCGTTCCGGGTCCCGACGTCGCCT
GGCGGCTCGACATGGAACAGGCCACGTTGATCGCCGGACCGCTGGAATGGACGGACGAGCGCCACGGCGTGCAGCAGGCC
CGGCCTGAAATGTTCGGCGACGTCGTGCTCTGGCGCAAGGACGCACCGGCCAGCTATCATCTTGCGGCAACGCTCGACGA
CGCGACCGATGGCATCACCCACGTGACGCGCGGGGTGGACCTGTTTCGTGCGACCCACGTCCACCGCCTGCTCCAGCACC
TTCTGGGCCTGCCGGTCCCGGTCTGGTACCACCACCCGGTGCTGGTGGAAGCCGACGGGCGCAAGCTCGCCAAGCGCCGC
GATGCGCCGGCCCTTGCCGACCGGCGCCGTGCCGGAGAGGACGGGCGCGCGGTCGCCGCCGAGGTGCGCGCTACCCTATT
TGACACTGGTATTTCGTTGTCCGACACCATAGATCAGAGCGCATGA

Upstream 100 bases:

>100_bases
AAAAGCGGCTGCCCCGGCGGGGCAGCCGTTTTGTTCATCTGCTGACCACACCTTCTGACGGGCTTCAACCCGGAGCGCGC
CCGCGCTAGTCATCTGCGGG

Downstream 100 bases:

>100_bases
ACTACGTCCTGATCCCGCTGATCATCATCTTCACCGTCATGACGGTCGTGTCGCTCGTGCGCGGGATCATCGCGTTTCTG
CACAGCACCCGGGAAGATCT

Product: glutamyl-tRNA synthetase, class Ic

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTVTRFAPSPNGPLHLGHAYSAIVAHDRAKRDNGEFLLRIEDIDGARSRPDLADEFRADLQWLRLDYREVAPQSQRIASY
RTAANELRAMGILYPCTCTRAEIAAAAVAQGPDGPLYPGTCLRRGPVPGPDVAWRLDMEQATLIAGPLEWTDERHGVQQA
RPEMFGDVVLWRKDAPASYHLAATLDDATDGITHVTRGVDLFRATHVHRLLQHLLGLPVPVWYHHPVLVEADGRKLAKRR
DAPALADRRRAGEDGRAVAAEVRATLFDTGISLSDTIDQSA

Sequences:

>Translated_281_residues
MTVTRFAPSPNGPLHLGHAYSAIVAHDRAKRDNGEFLLRIEDIDGARSRPDLADEFRADLQWLRLDYREVAPQSQRIASY
RTAANELRAMGILYPCTCTRAEIAAAAVAQGPDGPLYPGTCLRRGPVPGPDVAWRLDMEQATLIAGPLEWTDERHGVQQA
RPEMFGDVVLWRKDAPASYHLAATLDDATDGITHVTRGVDLFRATHVHRLLQHLLGLPVPVWYHHPVLVEADGRKLAKRR
DAPALADRRRAGEDGRAVAAEVRATLFDTGISLSDTIDQSA
>Mature_280_residues
TVTRFAPSPNGPLHLGHAYSAIVAHDRAKRDNGEFLLRIEDIDGARSRPDLADEFRADLQWLRLDYREVAPQSQRIASYR
TAANELRAMGILYPCTCTRAEIAAAAVAQGPDGPLYPGTCLRRGPVPGPDVAWRLDMEQATLIAGPLEWTDERHGVQQAR
PEMFGDVVLWRKDAPASYHLAATLDDATDGITHVTRGVDLFRATHVHRLLQHLLGLPVPVWYHHPVLVEADGRKLAKRRD
APALADRRRAGEDGRAVAAEVRATLFDTGISLSDTIDQSA

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=255, Percent_Identity=33.7254901960784, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI226510925, Length=247, Percent_Identity=34.8178137651822, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788743, Length=253, Percent_Identity=31.2252964426877, Blast_Score=113, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71993394, Length=255, Percent_Identity=29.4117647058824, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324540, Length=265, Percent_Identity=30.188679245283, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24665321, Length=277, Percent_Identity=32.8519855595668, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 30995; Mature: 30864

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTRFAPSPNGPLHLGHAYSAIVAHDRAKRDNGEFLLRIEDIDGARSRPDLADEFRADL
CCEEECCCCCCCCEEECHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHH
QWLRLDYREVAPQSQRIASYRTAANELRAMGILYPCTCTRAEIAAAAVAQGPDGPLYPGT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHCCCCCCCCCCC
CLRRGPVPGPDVAWRLDMEQATLIAGPLEWTDERHGVQQARPEMFGDVVLWRKDAPASYH
HHCCCCCCCCCCEEEECCCCCEEEECCCCCCCHHCCHHHHCHHHHCCEEEEECCCCCCEE
LAATLDDATDGITHVTRGVDLFRATHVHRLLQHLLGLPVPVWYHHPVLVEADGRKLAKRR
EEEECCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEECCCHHHHHHC
DAPALADRRRAGEDGRAVAAEVRATLFDTGISLSDTIDQSA
CCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCC
>Mature Secondary Structure 
TVTRFAPSPNGPLHLGHAYSAIVAHDRAKRDNGEFLLRIEDIDGARSRPDLADEFRADL
CEEECCCCCCCCEEECHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHH
QWLRLDYREVAPQSQRIASYRTAANELRAMGILYPCTCTRAEIAAAAVAQGPDGPLYPGT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHCCCCCCCCCCC
CLRRGPVPGPDVAWRLDMEQATLIAGPLEWTDERHGVQQARPEMFGDVVLWRKDAPASYH
HHCCCCCCCCCCEEEECCCCCEEEECCCCCCCHHCCHHHHCHHHHCCEEEEECCCCCCEE
LAATLDDATDGITHVTRGVDLFRATHVHRLLQHLLGLPVPVWYHHPVLVEADGRKLAKRR
EEEECCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEECCCHHHHHHC
DAPALADRRRAGEDGRAVAAEVRATLFDTGISLSDTIDQSA
CCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA