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The map label for this gene is etfA [H]

Identifier: 87198482

GI number: 87198482

Start: 501355

End: 502287

Strand: Direct

Name: etfA [H]

Synonym: Saro_0457

Alternate gene names: 87198482

Gene position: 501355-502287 (Clockwise)

Preceding gene: 87198481

Following gene: 87198483

Centisome position: 14.08

GC content: 68.38

Gene sequence:

>933_bases
ATGACCAAGGTTCTCGTTCTCGTCGAACACGACAACGCCAGCGTCAAGGACGCGACCCTTGCCGCCGTCACCGCCGCGGG
CCAGCTTGGCGAAGTGACCGCGCTGGTTGCGGGCGAGGGTTGCGATGCCGCCGCCCAGGCTGCCGCGCAGATCGCGGGCG
TGGCCAAGGTGCTCAAGGCCGATGATGCATCGCTTGCCAACGCGCTGGCGGAAAACGTCGCGCCGCTGGTCGCCGGCCTG
ATGGCCGGTTACGACGCCTTCGTCGCCCCGGCGACGACCACCGGCAAGAACGTCGCCCCGCGCGTCGCCGCGCTGCTCGA
CGTGATGCAGATCTCCGACATCCTCTCGGTCGAGGGGCCCAGGACCTTCACCCGCCCGATCTATGCCGGCAACGCCATCG
CCACGGTCGAAAGCTCTGACGCCAAGCTGGTGATCACCGTGCGCGGCACCGCCTTTGCCAAGGCGGCCGCCACCGGCGGA
TCGGCCAGCGTCGAGAGCACCGGCGCCAACGGCGACAGCGGCCTGTCGACCTTCGTCAGCGCCGAGATCGCCAAGTCCGA
GCGTCCGGAACTGACCAGCGCCAAGATCATCGTCTCGGGCGGCCGCGCGCTCAAGGACGCCGCCACGTTCGAGCAGGTGA
TCACCCCGCTTGCCGACAAGCTTGGCGCGGGCATCGGCGCGAGCCGCGCGGCGGTGGACGCGGGCTACGTGCCCAACGAC
TACCAGGTCGGCCAGACGGGCAAGATCGTGGCGCCGGAAGTCTACATCGCGATCGGCATCTCGGGCGCGATCCAGCACCT
TGCGGGGATGAAGGACAGCAAGACCATCATCGCCATCAACAAGGACGAGGACGCCCCGATCTTCCAGGTTGCCGACATCG
GCCTGGTGGGCGACCTGTTCACGCTGGTCCCGGAACTGACGGGCAAGCTCTGA

Upstream 100 bases:

>100_bases
AGACGCTGAAGGTCTCCGAACCGCCGGTCCGTTCGGCCGGGATCAAGGTGGCCGACGTCGACGCGCTCGTCGCCAAGCTC
AAGGAAATGGGAGTCGCCTG

Downstream 100 bases:

>100_bases
CCGCTCCATGTTGGAAAGTTTCCCCGGGGAAACATTCCATATAGGTTACCCAACCGCACAGGCCCCGCCCCCACAGGCGG
GGCCTTCCGCGTTCGGGCAC

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTKVLVLVEHDNASVKDATLAAVTAAGQLGEVTALVAGEGCDAAAQAAAQIAGVAKVLKADDASLANALAENVAPLVAGL
MAGYDAFVAPATTTGKNVAPRVAALLDVMQISDILSVEGPRTFTRPIYAGNAIATVESSDAKLVITVRGTAFAKAAATGG
SASVESTGANGDSGLSTFVSAEIAKSERPELTSAKIIVSGGRALKDAATFEQVITPLADKLGAGIGASRAAVDAGYVPND
YQVGQTGKIVAPEVYIAIGISGAIQHLAGMKDSKTIIAINKDEDAPIFQVADIGLVGDLFTLVPELTGKL

Sequences:

>Translated_310_residues
MTKVLVLVEHDNASVKDATLAAVTAAGQLGEVTALVAGEGCDAAAQAAAQIAGVAKVLKADDASLANALAENVAPLVAGL
MAGYDAFVAPATTTGKNVAPRVAALLDVMQISDILSVEGPRTFTRPIYAGNAIATVESSDAKLVITVRGTAFAKAAATGG
SASVESTGANGDSGLSTFVSAEIAKSERPELTSAKIIVSGGRALKDAATFEQVITPLADKLGAGIGASRAAVDAGYVPND
YQVGQTGKIVAPEVYIAIGISGAIQHLAGMKDSKTIIAINKDEDAPIFQVADIGLVGDLFTLVPELTGKL
>Mature_309_residues
TKVLVLVEHDNASVKDATLAAVTAAGQLGEVTALVAGEGCDAAAQAAAQIAGVAKVLKADDASLANALAENVAPLVAGLM
AGYDAFVAPATTTGKNVAPRVAALLDVMQISDILSVEGPRTFTRPIYAGNAIATVESSDAKLVITVRGTAFAKAAATGGS
ASVESTGANGDSGLSTFVSAEIAKSERPELTSAKIIVSGGRALKDAATFEQVITPLADKLGAGIGASRAAVDAGYVPNDY
QVGQTGKIVAPEVYIAIGISGAIQHLAGMKDSKTIIAINKDEDAPIFQVADIGLVGDLFTLVPELTGKL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=306, Percent_Identity=55.2287581699346, Blast_Score=318, Evalue=4e-87,
Organism=Homo sapiens, GI189181759, Length=267, Percent_Identity=55.8052434456929, Blast_Score=285, Evalue=3e-77,
Organism=Escherichia coli, GI1786226, Length=251, Percent_Identity=33.0677290836653, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787990, Length=256, Percent_Identity=30.078125, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082157, Length=219, Percent_Identity=32.8767123287671, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17506929, Length=314, Percent_Identity=55.4140127388535, Blast_Score=313, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6325261, Length=286, Percent_Identity=48.6013986013986, Blast_Score=270, Evalue=2e-73,
Organism=Drosophila melanogaster, GI17136898, Length=311, Percent_Identity=59.1639871382637, Blast_Score=328, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24652801, Length=311, Percent_Identity=59.1639871382637, Blast_Score=328, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31086; Mature: 30954

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVLVLVEHDNASVKDATLAAVTAAGQLGEVTALVAGEGCDAAAQAAAQIAGVAKVLKA
CCEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHC
DDASLANALAENVAPLVAGLMAGYDAFVAPATTTGKNVAPRVAALLDVMQISDILSVEGP
CCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
RTFTRPIYAGNAIATVESSDAKLVITVRGTAFAKAAATGGSASVESTGANGDSGLSTFVS
CCCCCCEECCCEEEEEECCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
AEIAKSERPELTSAKIIVSGGRALKDAATFEQVITPLADKLGAGIGASRAAVDAGYVPND
HHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCC
YQVGQTGKIVAPEVYIAIGISGAIQHLAGMKDSKTIIAINKDEDAPIFQVADIGLVGDLF
CEECCCCCEECCEEEEEEECHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCHHHHHH
TLVPELTGKL
HHHHHHHCCC
>Mature Secondary Structure 
TKVLVLVEHDNASVKDATLAAVTAAGQLGEVTALVAGEGCDAAAQAAAQIAGVAKVLKA
CEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHC
DDASLANALAENVAPLVAGLMAGYDAFVAPATTTGKNVAPRVAALLDVMQISDILSVEGP
CCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
RTFTRPIYAGNAIATVESSDAKLVITVRGTAFAKAAATGGSASVESTGANGDSGLSTFVS
CCCCCCEECCCEEEEEECCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
AEIAKSERPELTSAKIIVSGGRALKDAATFEQVITPLADKLGAGIGASRAAVDAGYVPND
HHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCC
YQVGQTGKIVAPEVYIAIGISGAIQHLAGMKDSKTIIAINKDEDAPIFQVADIGLVGDLF
CEECCCCCEECCEEEEEEECHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCHHHHHH
TLVPELTGKL
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]