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The map label for this gene is gmhA [H]

Identifier: 86750921

GI number: 86750921

Start: 4350063

End: 4350749

Strand: Reverse

Name: gmhA [H]

Synonym: RPB_3812

Alternate gene names: 86750921

Gene position: 4350749-4350063 (Counterclockwise)

Preceding gene: 86750922

Following gene: 86750920

Centisome position: 81.6

GC content: 66.52

Gene sequence:

>687_bases
ATGATGAAGTCGCGCAAGACGAAGACCCGGGAGCCGCTCTCCCCAGAATCGTCGGGTGATATCCACGCGGATGTCGCCCC
GAGCCCGCTGGTCTCCAAGGCGCAGCTGCTCGGCTATTTCGACTTCCTCCGTGACACGCTCGCCGCCACCCAGGTCTCCG
ATCGCGAAGGCCGGACCTTCGGTCCGGAGGTCGCGGCTTCGCTGGTGATGGCCTGGGCGCGCGAGGCCCATGCCGACGGC
CGCAAGCTGATCTTCATCGGCAATGGCGGCAGCGCCGCGATCGCCAGTCACATGGCGACCGATTATTCCAAGAACGGCGG
CATGCGCGCGCTGTGCCTGAACGACGGCGCGATGCTGACCTGCCTCGGCAATGACTACGGCTACGAGCAGGTGTTCGCCA
AGCAGATCGAGCTGTTCGCGCAGGACGGCGACCTGCTGATCGCGATCTCGAGCTCGGGCCGCTCGCCGAACATCCTCAAC
GCGGTGGCGGTGGCGGAGCAGCGCGGCTGCCGAATCGTGACGCTGAGCGGCTTCTCCGCCGACAACCCGCTGCGCGGCCA
GGGCGATATCAATTTCTATCTCGCTTCGGAGCAATACGGCTTCGTGGAGATCGGCCATCTGACGCTGTGCCACGCCATCC
TCGATTTCGCCTGCGGCCAGCGCGTGCCGCTGCCGGCCGCCCCCTGA

Upstream 100 bases:

>100_bases
CGGCGCTGTTTTGTTTCCGCTCCGTGTCTGCGCGTTGCCAGTTTGTTGCGATTCAGTCATTAGTGACGAATCACGCGCAT
CTTGGGCGCCTGGAACGCAG

Downstream 100 bases:

>100_bases
TCGCGCCGCGCGGCCCTACCAGCGCGTGAAACAATGCACGTATGTCTCGCCGGCGATGCAGCAGTAGTTCGGGAATGCGG
CGGATACGCCGCGATCCAGA

Product: sugar isomerase (SIS)

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MMKSRKTKTREPLSPESSGDIHADVAPSPLVSKAQLLGYFDFLRDTLAATQVSDREGRTFGPEVAASLVMAWAREAHADG
RKLIFIGNGGSAAIASHMATDYSKNGGMRALCLNDGAMLTCLGNDYGYEQVFAKQIELFAQDGDLLIAISSSGRSPNILN
AVAVAEQRGCRIVTLSGFSADNPLRGQGDINFYLASEQYGFVEIGHLTLCHAILDFACGQRVPLPAAP

Sequences:

>Translated_228_residues
MMKSRKTKTREPLSPESSGDIHADVAPSPLVSKAQLLGYFDFLRDTLAATQVSDREGRTFGPEVAASLVMAWAREAHADG
RKLIFIGNGGSAAIASHMATDYSKNGGMRALCLNDGAMLTCLGNDYGYEQVFAKQIELFAQDGDLLIAISSSGRSPNILN
AVAVAEQRGCRIVTLSGFSADNPLRGQGDINFYLASEQYGFVEIGHLTLCHAILDFACGQRVPLPAAP
>Mature_228_residues
MMKSRKTKTREPLSPESSGDIHADVAPSPLVSKAQLLGYFDFLRDTLAATQVSDREGRTFGPEVAASLVMAWAREAHADG
RKLIFIGNGGSAAIASHMATDYSKNGGMRALCLNDGAMLTCLGNDYGYEQVFAKQIELFAQDGDLLIAISSSGRSPNILN
AVAVAEQRGCRIVTLSGFSADNPLRGQGDINFYLASEQYGFVEIGHLTLCHAILDFACGQRVPLPAAP

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=145, Percent_Identity=30.3448275862069, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789539, Length=146, Percent_Identity=31.5068493150685, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 24356; Mature: 24356

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKSRKTKTREPLSPESSGDIHADVAPSPLVSKAQLLGYFDFLRDTLAATQVSDREGRTF
CCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GPEVAASLVMAWAREAHADGRKLIFIGNGGSAAIASHMATDYSKNGGMRALCLNDGAMLT
CHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCEEEE
CLGNDYGYEQVFAKQIELFAQDGDLLIAISSSGRSPNILNAVAVAEQRGCRIVTLSGFSA
EECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEECCCC
DNPLRGQGDINFYLASEQYGFVEIGHLTLCHAILDFACGQRVPLPAAP
CCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MMKSRKTKTREPLSPESSGDIHADVAPSPLVSKAQLLGYFDFLRDTLAATQVSDREGRTF
CCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GPEVAASLVMAWAREAHADGRKLIFIGNGGSAAIASHMATDYSKNGGMRALCLNDGAMLT
CHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCEEEE
CLGNDYGYEQVFAKQIELFAQDGDLLIAISSSGRSPNILNAVAVAEQRGCRIVTLSGFSA
EECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEECCCC
DNPLRGQGDINFYLASEQYGFVEIGHLTLCHAILDFACGQRVPLPAAP
CCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA