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The map label for this gene is crp [C]

Identifier: 86750858

GI number: 86750858

Start: 4286487

End: 4287173

Strand: Reverse

Name: crp [C]

Synonym: RPB_3749

Alternate gene names: 86750858

Gene position: 4287173-4286487 (Counterclockwise)

Preceding gene: 86750859

Following gene: 86750853

Centisome position: 80.41

GC content: 61.72

Gene sequence:

>687_bases
GTGAATTCCAACGAAGCGGCGTTCGATCCCACCGCGTTTCTCGGCAGCGCTGGACCGGGCCGGTCCATACAGCAATTCCG
CAAGAACCAGAGCATTTTCGCGCAAGGCGACAAGGCCGACAGCGTGCTGTTTCTTCAGCATGGTCGCGTCAAGCTGGTGG
TGATGTCGGAGCAGGGCAAAGAGGGCGTCGTCGCGATCCTTGAATCGGGGCAGTTCTTGGGCGAGAGCGCGCTGATCGGC
CGGCGGCGCCTGTCCACCGCGGTGGCGCTCGAGGACTGCATCGTCACCACGCTGACCAACACGGTGCTGATCGCGACGCT
GCAGCGCGAGCCCGGCATGTGCGAGTTCTTCATGACTCACCTGCTCAGGCGCAATTGCCGCGTCGAGGAGGATTTGATCG
ATCAGTTGTTCAATTCCAGCGAGAAGCGCCTGGCACGACTGTTACTTCTGCTCGCTGATTTCCACCCGGGCGACACCGCC
AAATCGCTGCCTGTCGATGTCAGCCAGGAGACTCTGGCGGAGATGATCGGCACGACGCGATCGCGCGTCAGTCACTTCAT
GAACAAGTTCCGCAAGCTCGGCTTCATCGACTACAACGGCCACATCGAAGTGTATCCGTCGCTACGCAGCGCTGTGTCGC
CGGACAAGGCGCGGCTGCCCGAAGGCGATGCGCGGCCTTTCGACTGA

Upstream 100 bases:

>100_bases
TGGAAATTGATGTTGATGGACCGACGCGGCGAGTGTTTCGCCGCGCGGCTCTTCCAGCGATCGATGGCGGAGGGCTTGCT
CCGCGATTGCAGGATGAGAC

Downstream 100 bases:

>100_bases
ACGGCCGGATGGCGATCGCCGAAGCGACCGGTGGGCGGTGCGACCCCGCTCAGCCCCTGTCGCCGAGCAGCCGGCCCGAC
GAGCGATTGATGAAATGCAC

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: Transcriptional Regulator Crp/Fnr Family; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Transcriptional Regulator; Response Regulator Receiver; Crp/Fnr Family Transcriptional Regulator; CAMP Receptor Protein; CAMP-Regulatory Protein; Cyclic-AMP Receptor-Like Protein

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MNSNEAAFDPTAFLGSAGPGRSIQQFRKNQSIFAQGDKADSVLFLQHGRVKLVVMSEQGKEGVVAILESGQFLGESALIG
RRRLSTAVALEDCIVTTLTNTVLIATLQREPGMCEFFMTHLLRRNCRVEEDLIDQLFNSSEKRLARLLLLLADFHPGDTA
KSLPVDVSQETLAEMIGTTRSRVSHFMNKFRKLGFIDYNGHIEVYPSLRSAVSPDKARLPEGDARPFD

Sequences:

>Translated_228_residues
MNSNEAAFDPTAFLGSAGPGRSIQQFRKNQSIFAQGDKADSVLFLQHGRVKLVVMSEQGKEGVVAILESGQFLGESALIG
RRRLSTAVALEDCIVTTLTNTVLIATLQREPGMCEFFMTHLLRRNCRVEEDLIDQLFNSSEKRLARLLLLLADFHPGDTA
KSLPVDVSQETLAEMIGTTRSRVSHFMNKFRKLGFIDYNGHIEVYPSLRSAVSPDKARLPEGDARPFD
>Mature_228_residues
MNSNEAAFDPTAFLGSAGPGRSIQQFRKNQSIFAQGDKADSVLFLQHGRVKLVVMSEQGKEGVVAILESGQFLGESALIG
RRRLSTAVALEDCIVTTLTNTVLIATLQREPGMCEFFMTHLLRRNCRVEEDLIDQLFNSSEKRLARLLLLLADFHPGDTA
KSLPVDVSQETLAEMIGTTRSRVSHFMNKFRKLGFIDYNGHIEVYPSLRSAVSPDKARLPEGDARPFD

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25300; Mature: 25300

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSNEAAFDPTAFLGSAGPGRSIQQFRKNQSIFAQGDKADSVLFLQHGRVKLVVMSEQGK
CCCCCCCCCCHHHHCCCCCCHHHHHHHCCCCEEECCCCCCCEEEEECCCEEEEEECCCCC
EGVVAILESGQFLGESALIGRRRLSTAVALEDCIVTTLTNTVLIATLQREPGMCEFFMTH
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHH
LLRRNCRVEEDLIDQLFNSSEKRLARLLLLLADFHPGDTAKSLPVDVSQETLAEMIGTTR
HHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCHH
SRVSHFMNKFRKLGFIDYNGHIEVYPSLRSAVSPDKARLPEGDARPFD
HHHHHHHHHHHHCCCEEECCCEEEEECHHHHCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MNSNEAAFDPTAFLGSAGPGRSIQQFRKNQSIFAQGDKADSVLFLQHGRVKLVVMSEQGK
CCCCCCCCCCHHHHCCCCCCHHHHHHHCCCCEEECCCCCCCEEEEECCCEEEEEECCCCC
EGVVAILESGQFLGESALIGRRRLSTAVALEDCIVTTLTNTVLIATLQREPGMCEFFMTH
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHH
LLRRNCRVEEDLIDQLFNSSEKRLARLLLLLADFHPGDTAKSLPVDVSQETLAEMIGTTR
HHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCHH
SRVSHFMNKFRKLGFIDYNGHIEVYPSLRSAVSPDKARLPEGDARPFD
HHHHHHHHHHHHCCCEEECCCEEEEECHHHHCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA