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The map label for this gene is purQ

Identifier: 86750826

GI number: 86750826

Start: 4255015

End: 4255716

Strand: Reverse

Name: purQ

Synonym: RPB_3716

Alternate gene names: 86750826

Gene position: 4255716-4255015 (Counterclockwise)

Preceding gene: 86750827

Following gene: 86750824

Centisome position: 79.82

GC content: 66.81

Gene sequence:

>702_bases
ATGAAATCCGCTGTCCTCGTCTTCCCCGGCATCAATCGTGAGCGCGACATGGCGCGCGCGCTGAAGCTCGTCTCCGGCCA
TGACGCCGCGATGGTCTGGCATGCCGACACCGAACTGCCGAACGGCACCGATCTCGTGGTGGTGCCGGGCGGCTTCTCCT
ACGGCGATTATCTGCGCTGCGGCGCCATCGCGGCGCGGGCGCCGGTGATGGACGCGGTGCGCAAATTCGCGAGTGACGGC
GGCCTGGTGCTCGGCGTCTGCAACGGCTTCCAGATCCTGTGCGAGTCCGGCCTCTTGCCAGGCGTCTTGATGCGCAACGC
GCGGCTGAAATTCATCTGCCGCGACGTGCATCTGCGGGTCGAGCGCAACGACAGCCCGTTCACCCGCGGCTATGCGGCCG
GGCAGGTGATCAAGGTGCCGGTCGCGCACGGCGAAGGCAATTACGAAGCCGACGAAGAGACCGTGAAGCGCCTCGAGGGC
GACGGCCGTGTGCTGTATCGCTACTGCTCGCCCGAGGGCGAGATCGGCGAGAGCCATAACATCAACGGCGCCGCCGCCTC
GATCGCCGGCATCGTCAGCGAGCGCGGCAACGTGCTGGGCATGATGCCGCATCCGGAAAACCACGTCGAAGACATCATGG
GCTGCACCGACGGCCGCGGCCTGTTCGCGGGGCTGGTGGAGCATTTGAAGACGGCGGCGTAG

Upstream 100 bases:

>100_bases
ACAATGAACTCGCCGGCATCCATGCCACGTTGATGCGACACGATCAGCAACTCGACCGCATCGAACGGCGCCTTGAGATC
AACGACATCCCTGCATTGAC

Downstream 100 bases:

>100_bases
TTAGTTAGCGCCGGGGCGCGCGGCGTCGCATCCCTCGTCATTGCCGGGCTTGACCCGGCAATCCATCTTCTTCGTCAGAA
CGACCTTGTCGTGCTCACCG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKSAVLVFPGINRERDMARALKLVSGHDAAMVWHADTELPNGTDLVVVPGGFSYGDYLRCGAIAARAPVMDAVRKFASDG
GLVLGVCNGFQILCESGLLPGVLMRNARLKFICRDVHLRVERNDSPFTRGYAAGQVIKVPVAHGEGNYEADEETVKRLEG
DGRVLYRYCSPEGEIGESHNINGAAASIAGIVSERGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVEHLKTAA

Sequences:

>Translated_233_residues
MKSAVLVFPGINRERDMARALKLVSGHDAAMVWHADTELPNGTDLVVVPGGFSYGDYLRCGAIAARAPVMDAVRKFASDG
GLVLGVCNGFQILCESGLLPGVLMRNARLKFICRDVHLRVERNDSPFTRGYAAGQVIKVPVAHGEGNYEADEETVKRLEG
DGRVLYRYCSPEGEIGESHNINGAAASIAGIVSERGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVEHLKTAA
>Mature_233_residues
MKSAVLVFPGINRERDMARALKLVSGHDAAMVWHADTELPNGTDLVVVPGGFSYGDYLRCGAIAARAPVMDAVRKFASDG
GLVLGVCNGFQILCESGLLPGVLMRNARLKFICRDVHLRVERNDSPFTRGYAAGQVIKVPVAHGEGNYEADEETVKRLEG
DGRVLYRYCSPEGEIGESHNINGAAASIAGIVSERGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVEHLKTAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=225, Percent_Identity=35.1111111111111, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321498, Length=180, Percent_Identity=34.4444444444444, Blast_Score=79, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24582111, Length=238, Percent_Identity=31.0924369747899, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582109, Length=238, Percent_Identity=31.0924369747899, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17137292, Length=238, Percent_Identity=31.0924369747899, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_RHOP2 (Q2ITP9)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_487322.1
- ProteinModelPortal:   Q2ITP9
- SMR:   Q2ITP9
- STRING:   Q2ITP9
- GeneID:   3911518
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_3716
- eggNOG:   COG0047
- HOGENOM:   HBG302712
- OMA:   HPENHVE
- ProtClustDB:   PRK03619
- BioCyc:   RPAL316058:RPB_3716-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF07685 GATase_3

EC number: =6.3.5.3

Molecular weight: Translated: 24975; Mature: 24975

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS51273 GATASE_TYPE_1

Important sites: ACT_SITE 87-87 ACT_SITE 204-204 ACT_SITE 206-206

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAVLVFPGINRERDMARALKLVSGHDAAMVWHADTELPNGTDLVVVPGGFSYGDYLRC
CCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCHHHH
GAIAARAPVMDAVRKFASDGGLVLGVCNGFQILCESGLLPGVLMRNARLKFICRDVHLRV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCHHHHCCCCEEEEEEEEEEEE
ERNDSPFTRGYAAGQVIKVPVAHGEGNYEADEETVKRLEGDGRVLYRYCSPEGEIGESHN
ECCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCC
INGAAASIAGIVSERGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVEHLKTAA
CCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSAVLVFPGINRERDMARALKLVSGHDAAMVWHADTELPNGTDLVVVPGGFSYGDYLRC
CCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCHHHH
GAIAARAPVMDAVRKFASDGGLVLGVCNGFQILCESGLLPGVLMRNARLKFICRDVHLRV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCHHHHCCCCEEEEEEEEEEEE
ERNDSPFTRGYAAGQVIKVPVAHGEGNYEADEETVKRLEGDGRVLYRYCSPEGEIGESHN
ECCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCC
INGAAASIAGIVSERGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVEHLKTAA
CCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA