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The map label for this gene is cyaB [H]

Identifier: 86750509

GI number: 86750509

Start: 3883455

End: 3885443

Strand: Direct

Name: cyaB [H]

Synonym: RPB_3398

Alternate gene names: 86750509

Gene position: 3883455-3885443 (Clockwise)

Preceding gene: 86750508

Following gene: 86750512

Centisome position: 72.84

GC content: 66.42

Gene sequence:

>1989_bases
ATGAAGTTCACCACCCGATTGATCCTGCTCGTCACCGTGCTGACGGTCGGCGCGACGCTCGTCACCGCCGCGCTGCTCAC
CTGGACGACGCGCCGGGCCATCATCACCGAGGCGGAAGCCTCGGGCGAGATGGTCGCGCGGCTGCTGGCGCGCAGCGCCA
GCCTCGCCAGCTCGATTCCGGCCGAGGTGGAATCGATGATCGCCGACGAGATGGTGGCGCAAGGCAACATTCTGGCGCAT
TTCGTCGAGGCGGCGGAGCGCGCCGGCCTCGCGCCCGACGCGATCAATCGCCGGCTGAGGAGCATCACCGACGCGACCGT
GTTGGACGAAATCTGGATCACCGACGACAAGGGCCATGCTTATCTGCACAGCATGCCGGGGATCGACTTCACCTTCAGCT
CCTCGCCGCAGGTGCAGCCGCAAGCCTACGCGTTCTACGATCTGTTGACCGGCAAGCGGAAGGTGGTCGATCAGGAGGCG
CGCAAGCGCGACATCGACAATCAGCATTTCAAATATGTCGGCGTCGGCGGCATCGACAAGCCGAGGATCATTCAGGTCGG
GCGTAGCGCGAAACTGCTCGAGATGCTGACCGCGAAGGTCGGGCTGCCGCGGGCGGTGGAGAACCTGCTGGCAGACGGCG
ACATCGACGCGGTGTGGGTGTTCGACCGCAAGCTCGACGCGATCGTCGGCCCCGGCGTCTACGGCGTCGAGCGCCACGAC
GGTCCCAACAAACAAGAGCTGGGGCCGGTCGGCCTGGTGATTGCCGACGGCCAGACCCGGCACGTCGAGAGCCGGGAGAA
CCTGAGCGTCATCGCGCCGGTTCACAACGACAAGAAGGAGATCGTCGGCGCCGCCTTGGTCCGCCTGCCGATGAACCGGG
TGTGGGCGACAGTGCAGAGCCAGGCGGAGATCGCCGCGGCGACGGCATCCGCGATCGCGCTACTCGGCATTCTGCTGTCG
ATCGGCGTCGCACGCCACCAGTCCGCGCCGCTGCGTCAGATCACCCGCGCCGCGTCGGCGCTGGAATCCCAGACCTTCGA
GCCCGCGATGCTCGCGGCCGCCGCCGATCGCGGCGACGAACTCGGACAGTTGGCGCGGGTGTTCACCGGGATGGCCGGTC
AGGTCGCGGCCCGCGAGGAGCATCTCGATTCGATGGTGAGGCAGCGGACCGCCGAACTCGAAGCCCGCACCCGCAGCCTC
GAAGGCCTGTCGGCGGCGCTGTCGAAATATCTGTCGCCGCAGGTGTACTCCTCGATCTTCAGCGGCCATCAGGTCGCCGA
GATCGCCTCGAAGCGCAAGAAACTGACGATCTTCCTGTCGGACATCGCCGACTTCACCGCCACCACCGACAAGCTCGAAT
CCGAAGACCTGACGGCGATGCTCAACCGCTATCTCGCCGAGATGGCGCAGATCGCGCTGAAGCACGGCGCCACCATCGAC
AAATATGTCGGCGACGCCGTGCTCGCCTTCTTCGGCGATCCGCAGAGCCGCGGCGTCAAGGAGGACGCCGTCGCCTGCGT
GATGATGGCGATCGAGATGCAGACCAAGCTCAAGCAACTGGAGACGGAGTGGACGGCCGCGGGCGCGCAGCGGCCGTTCC
GGGTGCGGATCGGCATCAACACCGGCTATTGCACCGTCGGCAATTTCGGCAGCCCCGACCGGATGGACTACACCATCATC
GGCGGCGAGGTGAATCTCACCTCGCGGCTCGAACAGGCCTGCGAGCCGGGATCGATCCTGATCTCTCACGTCACCTGGTC
GCTGGTGAACGATGTCATCGACGCGGAGGAGCGACCGGCGCTGACCGTGAAGGGCTTCGGCGAGTCGGTCCGTGCCTACG
CGGTCCGCGGCCTCAAGGCCGCAACGCCGGCCGAGATCATTCGCAAGGAACTGCCCGGGATGCAGCTGTTCATCGACACC
GCCGCCGCCGATCGCACCGAAGTCCGCGAGACCCTCGCCAAGGTGGTGGCGGAGCTCGACGAAGCGTGA

Upstream 100 bases:

>100_bases
GTGAACCGAGCCGGCGCATTTGAACGGGCGACGGGGCGCGCATGATCCGAAACCTGGACGACCGAGTTTCGGAGGCGATC
ATGCAACAACAGGTTGTTCG

Downstream 100 bases:

>100_bases
GGATCACCCTCCCCTGCGAGGGGCGGGACAATCGCATTGAACATTTGCAGTCGCCGCGCGGCTCACCCTCCCCTGGAGGG
GGAGGGTCGCTCGCGTCAGC

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2; AC2 [H]

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MKFTTRLILLVTVLTVGATLVTAALLTWTTRRAIITEAEASGEMVARLLARSASLASSIPAEVESMIADEMVAQGNILAH
FVEAAERAGLAPDAINRRLRSITDATVLDEIWITDDKGHAYLHSMPGIDFTFSSSPQVQPQAYAFYDLLTGKRKVVDQEA
RKRDIDNQHFKYVGVGGIDKPRIIQVGRSAKLLEMLTAKVGLPRAVENLLADGDIDAVWVFDRKLDAIVGPGVYGVERHD
GPNKQELGPVGLVIADGQTRHVESRENLSVIAPVHNDKKEIVGAALVRLPMNRVWATVQSQAEIAAATASAIALLGILLS
IGVARHQSAPLRQITRAASALESQTFEPAMLAAAADRGDELGQLARVFTGMAGQVAAREEHLDSMVRQRTAELEARTRSL
EGLSAALSKYLSPQVYSSIFSGHQVAEIASKRKKLTIFLSDIADFTATTDKLESEDLTAMLNRYLAEMAQIALKHGATID
KYVGDAVLAFFGDPQSRGVKEDAVACVMMAIEMQTKLKQLETEWTAAGAQRPFRVRIGINTGYCTVGNFGSPDRMDYTII
GGEVNLTSRLEQACEPGSILISHVTWSLVNDVIDAEERPALTVKGFGESVRAYAVRGLKAATPAEIIRKELPGMQLFIDT
AAADRTEVRETLAKVVAELDEA

Sequences:

>Translated_662_residues
MKFTTRLILLVTVLTVGATLVTAALLTWTTRRAIITEAEASGEMVARLLARSASLASSIPAEVESMIADEMVAQGNILAH
FVEAAERAGLAPDAINRRLRSITDATVLDEIWITDDKGHAYLHSMPGIDFTFSSSPQVQPQAYAFYDLLTGKRKVVDQEA
RKRDIDNQHFKYVGVGGIDKPRIIQVGRSAKLLEMLTAKVGLPRAVENLLADGDIDAVWVFDRKLDAIVGPGVYGVERHD
GPNKQELGPVGLVIADGQTRHVESRENLSVIAPVHNDKKEIVGAALVRLPMNRVWATVQSQAEIAAATASAIALLGILLS
IGVARHQSAPLRQITRAASALESQTFEPAMLAAAADRGDELGQLARVFTGMAGQVAAREEHLDSMVRQRTAELEARTRSL
EGLSAALSKYLSPQVYSSIFSGHQVAEIASKRKKLTIFLSDIADFTATTDKLESEDLTAMLNRYLAEMAQIALKHGATID
KYVGDAVLAFFGDPQSRGVKEDAVACVMMAIEMQTKLKQLETEWTAAGAQRPFRVRIGINTGYCTVGNFGSPDRMDYTII
GGEVNLTSRLEQACEPGSILISHVTWSLVNDVIDAEERPALTVKGFGESVRAYAVRGLKAATPAEIIRKELPGMQLFIDT
AAADRTEVRETLAKVVAELDEA
>Mature_662_residues
MKFTTRLILLVTVLTVGATLVTAALLTWTTRRAIITEAEASGEMVARLLARSASLASSIPAEVESMIADEMVAQGNILAH
FVEAAERAGLAPDAINRRLRSITDATVLDEIWITDDKGHAYLHSMPGIDFTFSSSPQVQPQAYAFYDLLTGKRKVVDQEA
RKRDIDNQHFKYVGVGGIDKPRIIQVGRSAKLLEMLTAKVGLPRAVENLLADGDIDAVWVFDRKLDAIVGPGVYGVERHD
GPNKQELGPVGLVIADGQTRHVESRENLSVIAPVHNDKKEIVGAALVRLPMNRVWATVQSQAEIAAATASAIALLGILLS
IGVARHQSAPLRQITRAASALESQTFEPAMLAAAADRGDELGQLARVFTGMAGQVAAREEHLDSMVRQRTAELEARTRSL
EGLSAALSKYLSPQVYSSIFSGHQVAEIASKRKKLTIFLSDIADFTATTDKLESEDLTAMLNRYLAEMAQIALKHGATID
KYVGDAVLAFFGDPQSRGVKEDAVACVMMAIEMQTKLKQLETEWTAAGAQRPFRVRIGINTGYCTVGNFGSPDRMDYTII
GGEVNLTSRLEQACEPGSILISHVTWSLVNDVIDAEERPALTVKGFGESVRAYAVRGLKAATPAEIIRKELPGMQLFIDT
AAADRTEVRETLAKVVAELDEA

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17534659, Length=256, Percent_Identity=26.171875, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193207841, Length=248, Percent_Identity=27.0161290322581, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24585694, Length=167, Percent_Identity=27.5449101796407, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00072 Response_reg [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 71722; Mature: 71722

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTTRLILLVTVLTVGATLVTAALLTWTTRRAIITEAEASGEMVARLLARSASLASSIP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCH
AEVESMIADEMVAQGNILAHFVEAAERAGLAPDAINRRLRSITDATVLDEIWITDDKGHA
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCE
YLHSMPGIDFTFSSSPQVQPQAYAFYDLLTGKRKVVDQEARKRDIDNQHFKYVGVGGIDK
EEECCCCCCEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCC
PRIIQVGRSAKLLEMLTAKVGLPRAVENLLADGDIDAVWVFDRKLDAIVGPGVYGVERHD
CCEEECCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECCHHHHHCCCCCCCCCCCC
GPNKQELGPVGLVIADGQTRHVESRENLSVIAPVHNDKKEIVGAALVRLPMNRVWATVQS
CCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
QAEIAAATASAIALLGILLSIGVARHQSAPLRQITRAASALESQTFEPAMLAAAADRGDE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHH
LGQLARVFTGMAGQVAAREEHLDSMVRQRTAELEARTRSLEGLSAALSKYLSPQVYSSIF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
SGHQVAEIASKRKKLTIFLSDIADFTATTDKLESEDLTAMLNRYLAEMAQIALKHGATID
CCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
KYVGDAVLAFFGDPQSRGVKEDAVACVMMAIEMQTKLKQLETEWTAAGAQRPFRVRIGIN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
TGYCTVGNFGSPDRMDYTIIGGEVNLTSRLEQACEPGSILISHVTWSLVNDVIDAEERPA
CCEEECCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCE
LTVKGFGESVRAYAVRGLKAATPAEIIRKELPGMQLFIDTAAADRTEVRETLAKVVAELD
EEEECCCHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHC
EA
CC
>Mature Secondary Structure
MKFTTRLILLVTVLTVGATLVTAALLTWTTRRAIITEAEASGEMVARLLARSASLASSIP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCH
AEVESMIADEMVAQGNILAHFVEAAERAGLAPDAINRRLRSITDATVLDEIWITDDKGHA
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCE
YLHSMPGIDFTFSSSPQVQPQAYAFYDLLTGKRKVVDQEARKRDIDNQHFKYVGVGGIDK
EEECCCCCCEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCC
PRIIQVGRSAKLLEMLTAKVGLPRAVENLLADGDIDAVWVFDRKLDAIVGPGVYGVERHD
CCEEECCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECCHHHHHCCCCCCCCCCCC
GPNKQELGPVGLVIADGQTRHVESRENLSVIAPVHNDKKEIVGAALVRLPMNRVWATVQS
CCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
QAEIAAATASAIALLGILLSIGVARHQSAPLRQITRAASALESQTFEPAMLAAAADRGDE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHH
LGQLARVFTGMAGQVAAREEHLDSMVRQRTAELEARTRSLEGLSAALSKYLSPQVYSSIF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
SGHQVAEIASKRKKLTIFLSDIADFTATTDKLESEDLTAMLNRYLAEMAQIALKHGATID
CCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
KYVGDAVLAFFGDPQSRGVKEDAVACVMMAIEMQTKLKQLETEWTAAGAQRPFRVRIGIN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
TGYCTVGNFGSPDRMDYTIIGGEVNLTSRLEQACEPGSILISHVTWSLVNDVIDAEERPA
CCEEECCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCE
LTVKGFGESVRAYAVRGLKAATPAEIIRKELPGMQLFIDTAAADRTEVRETLAKVVAELD
EEEECCCHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHC
EA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]