Click here to switch to the map view.

The map label for this gene is fabZ [H]

Identifier: 86750465

GI number: 86750465

Start: 3835771

End: 3836241

Strand: Direct

Name: fabZ [H]

Synonym: RPB_3354

Alternate gene names: 86750465

Gene position: 3835771-3836241 (Clockwise)

Preceding gene: 86750464

Following gene: 86750466

Centisome position: 71.94

GC content: 61.36

Gene sequence:

>471_bases
ATGAACCTCGAATATTTCCATCTGATCGATCGGATCGCCGACCTTCGTCTCGAGCAGCGCAGCATCACGGTCGAAGCGCT
GGTGCCGCAGACGAGCACCATCTTCGAGGGTCATTTCCCCGGCTATCCGCTGATGCCGGGCGTGTTGCTGATCGAAACGA
TGGCGCAGACCTCCGGCTGGCTGCTGATCGCACTGATGCAGTTCCAACGCATGCCGTTCCTGGCGGCGGTCAAGGAAGCC
AAGATGCGCAGCTTCGTCACGCCCGGCGAGATGCTCTCTGTCGATGCCACGGTGGTCCACGAGGGCTCAGGCTACACCAT
GACCGAAGCGAACATCAGAAGCGGCGGCAAGCTGGCGTGCAACGCGGCGCTGACCTTCCGCCATGTGCCCTTTCCGCATC
CGGATCTGCGCGGGCACATGGAGACGATGGCCAGACAGATCGGATTTCCGGAGCAGATGATCCATGGCTGA

Upstream 100 bases:

>100_bases
ACCACCGAGCAGTATTTCGTCCTGAGCAACCTCGCCGCCCGCATCGACGAGTTGGTCGCCGCCAAGGGCGCGTAGTGGCG
CGGTTCGAAAGCCGCCCGCG

Downstream 100 bases:

>100_bases
GACGTCGCACAAACAACCTGTGGAAGCCTGGATCACCGGCATCGGACTCGCGACTTCGCTGGCTGAAGGCCTCGACGCGC
ATTGGGACGCGCTGGCGGAG

Product: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MNLEYFHLIDRIADLRLEQRSITVEALVPQTSTIFEGHFPGYPLMPGVLLIETMAQTSGWLLIALMQFQRMPFLAAVKEA
KMRSFVTPGEMLSVDATVVHEGSGYTMTEANIRSGGKLACNAALTFRHVPFPHPDLRGHMETMARQIGFPEQMIHG

Sequences:

>Translated_156_residues
MNLEYFHLIDRIADLRLEQRSITVEALVPQTSTIFEGHFPGYPLMPGVLLIETMAQTSGWLLIALMQFQRMPFLAAVKEA
KMRSFVTPGEMLSVDATVVHEGSGYTMTEANIRSGGKLACNAALTFRHVPFPHPDLRGHMETMARQIGFPEQMIHG
>Mature_156_residues
MNLEYFHLIDRIADLRLEQRSITVEALVPQTSTIFEGHFPGYPLMPGVLLIETMAQTSGWLLIALMQFQRMPFLAAVKEA
KMRSFVTPGEMLSVDATVVHEGSGYTMTEANIRSGGKLACNAALTFRHVPFPHPDLRGHMETMARQIGFPEQMIHG

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=122, Percent_Identity=31.1475409836066, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17458; Mature: 17458

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEYFHLIDRIADLRLEQRSITVEALVPQTSTIFEGHFPGYPLMPGVLLIETMAQTSGW
CCCHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCH
LLIALMQFQRMPFLAAVKEAKMRSFVTPGEMLSVDATVVHEGSGYTMTEANIRSGGKLAC
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEECCEEEEECCCCCEEEECCCCCCCCEEE
NAALTFRHVPFPHPDLRGHMETMARQIGFPEQMIHG
EEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MNLEYFHLIDRIADLRLEQRSITVEALVPQTSTIFEGHFPGYPLMPGVLLIETMAQTSGW
CCCHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCH
LLIALMQFQRMPFLAAVKEAKMRSFVTPGEMLSVDATVVHEGSGYTMTEANIRSGGKLAC
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEECCEEEEECCCCCEEEECCCCCCCCEEE
NAALTFRHVPFPHPDLRGHMETMARQIGFPEQMIHG
EEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA