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The map label for this gene is serB [C]

Identifier: 86750458

GI number: 86750458

Start: 3829179

End: 3830072

Strand: Direct

Name: serB [C]

Synonym: RPB_3347

Alternate gene names: 86750458

Gene position: 3829179-3830072 (Clockwise)

Preceding gene: 86750454

Following gene: 86750459

Centisome position: 71.82

GC content: 68.68

Gene sequence:

>894_bases
ATGTCGCTCGTCGCCACGCTCATCTGCAATCCAAACAGTCCCGCGCTGGATTCCACCGTGCTCGAAGGCGCGCGCGCCGT
GCTGCCACAGCCGAACGCCGCGGTCTGGCTGCACGACGAGGTCGCCGCCGACATCACCTTCAGCAGCGACGACGACGCCC
TGGCCCTCGCCGACCGGCTGCGCGACGCGCGCGGCGATCTGCCGATCGACGTCGTCGTGCAGCCTCTCGCCACCAGGCGC
AAGAAGCTTTTTCTCGCCGACATGGATTCGACCATGATCGGCCAGGAATGCATCGACGAACTCGCCGACTTCGTCGGGCT
GAAGAGCCACGTCGCCGCGATCACCGAGCGCGCGATGCGCGGCGAGATCGAATTCGAGCCGGCGCTGCGCGAGCGCGTGG
CGCTGCTGAAGGGGCTTTCGCTCGACATCATCGACAAGGTGCTGGCGACCCGCATCACGCTCAATCCCGGCGGCCGCGCG
CTGGTGCAGACGATGCGCGCAAACGGCGCCTATACGTGTCTGGTCTCCGGCGGCTTCACGCAGTTCACCCAGGCGGTCGC
AGCGCGTCTCGGCTTCGCCGAGCATCGCGCCAACGAATTGCTGAGCGAGGACGGCAAGCTCACCGGCCGCGTCGCCGAGC
CGATCCTCGGCCGCGAAGCCAAGCTGGCGACGCTGCTGGAGTTGCGCGAAGCCGACGACCTCGACGCCATCGACACGCTG
GCGATCGGCGACGGCGCCAACGACCTCGGCATGATCCAGGCCGCCGGCCTCGGCATCGCCTACCACGCCAAGCCCGCGGT
CGCCGCCAGCGCCCACGGCCGCATCGACCACGCCGACCTCACTGCGCTGCTGTACGCGCAAGGCTACAGGCGCAGCGAAT
TCGTCGGCGATTAG

Upstream 100 bases:

>100_bases
CTGCGCAAGCCGCAGCGCGAGCGCCGACTTGCCGCTGGCGGTCGGCCCTGCGATAAGCACGGCCGCCGGCTTTTGCCCCT
GCTCCGGAACCGTTTTTCCC

Downstream 100 bases:

>100_bases
GCCGCCGCGCATCGGCGCGCCCCGGAATGACGGAGACGCGTAGAGGGCTTCCGCGTCGCTAGCACGGCCCGACCTTCGAC
GATGATCCGCGTGTCCCGCA

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSLVATLICNPNSPALDSTVLEGARAVLPQPNAAVWLHDEVAADITFSSDDDALALADRLRDARGDLPIDVVVQPLATRR
KKLFLADMDSTMIGQECIDELADFVGLKSHVAAITERAMRGEIEFEPALRERVALLKGLSLDIIDKVLATRITLNPGGRA
LVQTMRANGAYTCLVSGGFTQFTQAVAARLGFAEHRANELLSEDGKLTGRVAEPILGREAKLATLLELREADDLDAIDTL
AIGDGANDLGMIQAAGLGIAYHAKPAVAASAHGRIDHADLTALLYAQGYRRSEFVGD

Sequences:

>Translated_297_residues
MSLVATLICNPNSPALDSTVLEGARAVLPQPNAAVWLHDEVAADITFSSDDDALALADRLRDARGDLPIDVVVQPLATRR
KKLFLADMDSTMIGQECIDELADFVGLKSHVAAITERAMRGEIEFEPALRERVALLKGLSLDIIDKVLATRITLNPGGRA
LVQTMRANGAYTCLVSGGFTQFTQAVAARLGFAEHRANELLSEDGKLTGRVAEPILGREAKLATLLELREADDLDAIDTL
AIGDGANDLGMIQAAGLGIAYHAKPAVAASAHGRIDHADLTALLYAQGYRRSEFVGD
>Mature_296_residues
SLVATLICNPNSPALDSTVLEGARAVLPQPNAAVWLHDEVAADITFSSDDDALALADRLRDARGDLPIDVVVQPLATRRK
KLFLADMDSTMIGQECIDELADFVGLKSHVAAITERAMRGEIEFEPALRERVALLKGLSLDIIDKVLATRITLNPGGRAL
VQTMRANGAYTCLVSGGFTQFTQAVAARLGFAEHRANELLSEDGKLTGRVAEPILGREAKLATLLELREADDLDAIDTLA
IGDGANDLGMIQAAGLGIAYHAKPAVAASAHGRIDHADLTALLYAQGYRRSEFVGD

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=180, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1790849, Length=206, Percent_Identity=46.1165048543689, Blast_Score=157, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI115534454, Length=174, Percent_Identity=32.183908045977, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534456, Length=174, Percent_Identity=32.183908045977, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534458, Length=176, Percent_Identity=31.8181818181818, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=233, Percent_Identity=36.9098712446352, Blast_Score=152, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24661601, Length=189, Percent_Identity=29.1005291005291, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 31678; Mature: 31547

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVATLICNPNSPALDSTVLEGARAVLPQPNAAVWLHDEVAADITFSSDDDALALADRL
CCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHH
RDARGDLPIDVVVQPLATRRKKLFLADMDSTMIGQECIDELADFVGLKSHVAAITERAMR
HHHCCCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GEIEFEPALRERVALLKGLSLDIIDKVLATRITLNPGGRALVQTMRANGAYTCLVSGGFT
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCHHHHHHHHCCCCEEEEEECCHH
QFTQAVAARLGFAEHRANELLSEDGKLTGRVAEPILGREAKLATLLELREADDLDAIDTL
HHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHCCCHHHHHHHHHHCCCCCCHHHEE
AIGDGANDLGMIQAAGLGIAYHAKPAVAASAHGRIDHADLTALLYAQGYRRSEFVGD
EECCCCCCCCHHEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SLVATLICNPNSPALDSTVLEGARAVLPQPNAAVWLHDEVAADITFSSDDDALALADRL
CEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHH
RDARGDLPIDVVVQPLATRRKKLFLADMDSTMIGQECIDELADFVGLKSHVAAITERAMR
HHHCCCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GEIEFEPALRERVALLKGLSLDIIDKVLATRITLNPGGRALVQTMRANGAYTCLVSGGFT
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCHHHHHHHHCCCCEEEEEECCHH
QFTQAVAARLGFAEHRANELLSEDGKLTGRVAEPILGREAKLATLLELREADDLDAIDTL
HHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHCCCHHHHHHHHHHCCCCCCHHHEE
AIGDGANDLGMIQAAGLGIAYHAKPAVAASAHGRIDHADLTALLYAQGYRRSEFVGD
EECCCCCCCCHHEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]