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The map label for this gene is cobT [H]

Identifier: 86750393

GI number: 86750393

Start: 3754920

End: 3756017

Strand: Direct

Name: cobT [H]

Synonym: RPB_3282

Alternate gene names: 86750393

Gene position: 3754920-3756017 (Clockwise)

Preceding gene: 86750392

Following gene: 86750394

Centisome position: 70.43

GC content: 71.49

Gene sequence:

>1098_bases
GTGCGTCCGTTGCTATCAACCCATCGCGGTCTCATGCACGCTCCACGTTCCAGCCCGCCATTCTGCGCCATCGCTCCGGT
CGATCACGCGCTCGAACCGACCCTGCGCGCCCGGATCGACGCCAAGGCCAAGCCGCCCGGCTCGCTCGGCCGGCTGGAAG
ATCTCGCCGTGCAACTCGGGCTGATCTGGCATCCGGCGCCACCGCGCGCGGACCGCGCCACGGTGTTCGTGTTCGCCGCA
GATCATGGTCTCGCCGCCGAAAGCGTGTCGCCCTATCCGGCGAGCGTGACGCGGTCGATGGTCCGCGCCTATCTCGCCGG
CTGCGTCGGCGTGAACGTGCTGGCGAAAGCCGCCTTCACCGACCTCTGCGTCGTCGATGCGGGCATCGACGATGACCTGC
CGCCCTGCCCCGGGCTGATCGATCGCAAGATCCGGCGCGGCACCCGCAATGCGAGCCGCGAGCCGGCGATGTCGATCGAC
GAGGCGCGGCGCGCGATCGACGCCGCCGTCGCGCTGGTCAGCGACGCGATCGACGGCGGCGTCGACATCGTGGCGATCGG
CGAGATGGGCATCGGCAACACCACCTCGGCCGCGCTGATCACCCATCGTCTCGCCGCAGCGCCGATCGCCGACTGCGTCG
GCCGCGGCGCGGGGCTCGACGCCGCCGGCGTCGCCCACAAGCTCGCGATCGCGGAGAAGGCGTCAGCGCGCACCACGGCC
ACCGCCCCGCTCGACGTGCTCGCCGAATTCGGCGGCTTTGAAATCGCGATGATGGCCGGCGCCGTTCTGGCGGCGGCGGC
GCGGCGCCGTCCGGTGGTGATCGACGGCTTCATCGCCAGCGCCGCAGCGCTGGTCGCGGTGCGGCTGCATCCCGAGGCGC
GGGACTATTGCGTGTTCTCGCATCGCTCGGCCGAGCGCGGCCACAAGGTCCTGCTCGAGACGATGGCGGCGACGCCCTAT
CTCGATCTCGGCCTGCGGCTCGGCGAAGGCACCGGCGCGCTGATGGCGATTCCGCTGGTGCGCGCCGCCGCCGGAATCCT
CACCGACTTCGCCGACCTCTCCGACGTTCTGGCCGGCACCATCGGCACGCCGTCGTGA

Upstream 100 bases:

>100_bases
TCGGTTTCGCTTCGTCGTGCTGCCCGAGCTTGCTCGCAACGGCGCGAGGAGACGTCCGTCCGATCACCTCGACGCGTCCA
CCGCGCAGGCGGAGGCACGC

Downstream 100 bases:

>100_bases
CCGAACGCATCCGGCCGCTGCTGAACGCGATTCAGTTCATGACGGTGTTGCCGACGCGGGGAGCCGCGCGCCTCGACGCC
GATTGGGTGTTGTCCGCAGT

Product: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MRPLLSTHRGLMHAPRSSPPFCAIAPVDHALEPTLRARIDAKAKPPGSLGRLEDLAVQLGLIWHPAPPRADRATVFVFAA
DHGLAAESVSPYPASVTRSMVRAYLAGCVGVNVLAKAAFTDLCVVDAGIDDDLPPCPGLIDRKIRRGTRNASREPAMSID
EARRAIDAAVALVSDAIDGGVDIVAIGEMGIGNTTSAALITHRLAAAPIADCVGRGAGLDAAGVAHKLAIAEKASARTTA
TAPLDVLAEFGGFEIAMMAGAVLAAAARRRPVVIDGFIASAAALVAVRLHPEARDYCVFSHRSAERGHKVLLETMAATPY
LDLGLRLGEGTGALMAIPLVRAAAGILTDFADLSDVLAGTIGTPS

Sequences:

>Translated_365_residues
MRPLLSTHRGLMHAPRSSPPFCAIAPVDHALEPTLRARIDAKAKPPGSLGRLEDLAVQLGLIWHPAPPRADRATVFVFAA
DHGLAAESVSPYPASVTRSMVRAYLAGCVGVNVLAKAAFTDLCVVDAGIDDDLPPCPGLIDRKIRRGTRNASREPAMSID
EARRAIDAAVALVSDAIDGGVDIVAIGEMGIGNTTSAALITHRLAAAPIADCVGRGAGLDAAGVAHKLAIAEKASARTTA
TAPLDVLAEFGGFEIAMMAGAVLAAAARRRPVVIDGFIASAAALVAVRLHPEARDYCVFSHRSAERGHKVLLETMAATPY
LDLGLRLGEGTGALMAIPLVRAAAGILTDFADLSDVLAGTIGTPS
>Mature_365_residues
MRPLLSTHRGLMHAPRSSPPFCAIAPVDHALEPTLRARIDAKAKPPGSLGRLEDLAVQLGLIWHPAPPRADRATVFVFAA
DHGLAAESVSPYPASVTRSMVRAYLAGCVGVNVLAKAAFTDLCVVDAGIDDDLPPCPGLIDRKIRRGTRNASREPAMSID
EARRAIDAAVALVSDAIDGGVDIVAIGEMGIGNTTSAALITHRLAAAPIADCVGRGAGLDAAGVAHKLAIAEKASARTTA
TAPLDVLAEFGGFEIAMMAGAVLAAAARRRPVVIDGFIASAAALVAVRLHPEARDYCVFSHRSAERGHKVLLETMAATPY
LDLGLRLGEGTGALMAIPLVRAAAGILTDFADLSDVLAGTIGTPS

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=323, Percent_Identity=37.1517027863777, Blast_Score=197, Evalue=8e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 37678; Mature: 37678

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLLSTHRGLMHAPRSSPPFCAIAPVDHALEPTLRARIDAKAKPPGSLGRLEDLAVQLG
CCCHHHHHHHHHCCCCCCCCEEEECCCCHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHH
LIWHPAPPRADRATVFVFAADHGLAAESVSPYPASVTRSMVRAYLAGCVGVNVLAKAAFT
EEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLCVVDAGIDDDLPPCPGLIDRKIRRGTRNASREPAMSIDEARRAIDAAVALVSDAIDGG
HHEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
VDIVAIGEMGIGNTTSAALITHRLAAAPIADCVGRGAGLDAAGVAHKLAIAEKASARTTA
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
TAPLDVLAEFGGFEIAMMAGAVLAAAARRRPVVIDGFIASAAALVAVRLHPEARDYCVFS
CCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHEEEEECCCCCCEEEEE
HRSAERGHKVLLETMAATPYLDLGLRLGEGTGALMAIPLVRAAAGILTDFADLSDVLAGT
CCCHHHHHHHHHHHHHCCCHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IGTPS
CCCCC
>Mature Secondary Structure
MRPLLSTHRGLMHAPRSSPPFCAIAPVDHALEPTLRARIDAKAKPPGSLGRLEDLAVQLG
CCCHHHHHHHHHCCCCCCCCEEEECCCCHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHH
LIWHPAPPRADRATVFVFAADHGLAAESVSPYPASVTRSMVRAYLAGCVGVNVLAKAAFT
EEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLCVVDAGIDDDLPPCPGLIDRKIRRGTRNASREPAMSIDEARRAIDAAVALVSDAIDGG
HHEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
VDIVAIGEMGIGNTTSAALITHRLAAAPIADCVGRGAGLDAAGVAHKLAIAEKASARTTA
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
TAPLDVLAEFGGFEIAMMAGAVLAAAARRRPVVIDGFIASAAALVAVRLHPEARDYCVFS
CCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHEEEEECCCCCCEEEEE
HRSAERGHKVLLETMAATPYLDLGLRLGEGTGALMAIPLVRAAAGILTDFADLSDVLAGT
CCCHHHHHHHHHHHHHCCCHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IGTPS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA