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The map label for this gene is yohF [H]

Identifier: 86750333

GI number: 86750333

Start: 3684446

End: 3685207

Strand: Direct

Name: yohF [H]

Synonym: RPB_3222

Alternate gene names: 86750333

Gene position: 3684446-3685207 (Clockwise)

Preceding gene: 86750332

Following gene: 86750334

Centisome position: 69.11

GC content: 69.03

Gene sequence:

>762_bases
ATGTCCGCCACCAAGAAGATCGCCATCGTCACCGGCGCGGGCACCGGCGTCGGCCGCGCCGCCTCGCTGGCGCTGATGCA
GATCGGCTACACCGTCGTGCTCGCCGGCCGCCGGCTCGCGCTGCTGCAGGAAACGCAGACGCTCGGCGAAGCGATCGGCG
ACAGCCTGCCGGTGCAGGCCGACATGGCCGATCCCGCCTCGATCGCCGCGCTGTTCGACACCACCGTGAAGACCTACGGC
CGGCTCGATCTGTTGTTCAACAATGCCGGCATGGGCGCGCCGCCGGTGCCGTTCGAGGATCTGTCGCTGGCGCAATGGCA
GACCGTGGTCGACACCAACCTCACCGCGCCGTTTTTGTGCACCCAGCACGCCTTCCGCATCATGAAGGACCAGACCCCGC
GCGGCGGCCGCATCATCAACAACGGCTCGATCTCGGCGCACGCGCCGCGGCCGTTCTCGGCGGCCTACACCTCGACCAAG
CACGCGATTTCCGGCCTGACCAAGGCCAGCAATCTCGACGGCCGCGCCTATGACATCGCGGTCGGCCAGATCGACATCGG
CAACGCCGCGACCCCGATGACCGACCGCATGGTCGACGGCCCCGGCGTGCTGCAGCCGGACGGCTCGACCCGGCACGAGC
CGCGGATGGACGCCAAGGCGGTCGGCGATGCGGTGGCCTATATGGCCGCACTCCCGCTCGACGCCAACGTGCTGTTCATG
ACGGTGATGGCCACCAAGATGCCGTTCGTCGGCCGCGGCTGA

Upstream 100 bases:

>100_bases
CCCCCTCGCCTCGATGCCGGCCGGCTTGTTGAAGCGCGGGCCAGCCTCTACGATCCCGCCGACATTCGCCAACAACAGCA
AGAAACTCCGGGGAGACGCC

Downstream 100 bases:

>100_bases
GACGCCTCCGGTCGATGCCGGGGGGCGCCATTATTCGGTTGCCGATCGCCGGCCGATGCGGATGATGGCAGGCTGCGAGC
GAGGGAATCCGACCATGTCC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSATKKIAIVTGAGTGVGRAASLALMQIGYTVVLAGRRLALLQETQTLGEAIGDSLPVQADMADPASIAALFDTTVKTYG
RLDLLFNNAGMGAPPVPFEDLSLAQWQTVVDTNLTAPFLCTQHAFRIMKDQTPRGGRIINNGSISAHAPRPFSAAYTSTK
HAISGLTKASNLDGRAYDIAVGQIDIGNAATPMTDRMVDGPGVLQPDGSTRHEPRMDAKAVGDAVAYMAALPLDANVLFM
TVMATKMPFVGRG

Sequences:

>Translated_253_residues
MSATKKIAIVTGAGTGVGRAASLALMQIGYTVVLAGRRLALLQETQTLGEAIGDSLPVQADMADPASIAALFDTTVKTYG
RLDLLFNNAGMGAPPVPFEDLSLAQWQTVVDTNLTAPFLCTQHAFRIMKDQTPRGGRIINNGSISAHAPRPFSAAYTSTK
HAISGLTKASNLDGRAYDIAVGQIDIGNAATPMTDRMVDGPGVLQPDGSTRHEPRMDAKAVGDAVAYMAALPLDANVLFM
TVMATKMPFVGRG
>Mature_252_residues
SATKKIAIVTGAGTGVGRAASLALMQIGYTVVLAGRRLALLQETQTLGEAIGDSLPVQADMADPASIAALFDTTVKTYGR
LDLLFNNAGMGAPPVPFEDLSLAQWQTVVDTNLTAPFLCTQHAFRIMKDQTPRGGRIINNGSISAHAPRPFSAAYTSTKH
AISGLTKASNLDGRAYDIAVGQIDIGNAATPMTDRMVDGPGVLQPDGSTRHEPRMDAKAVGDAVAYMAALPLDANVLFMT
VMATKMPFVGRG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=168, Percent_Identity=30.3571428571429, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI31542939, Length=176, Percent_Identity=32.3863636363636, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=32.183908045977, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI19923817, Length=142, Percent_Identity=32.3943661971831, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI59889578, Length=179, Percent_Identity=27.3743016759777, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI209862901, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI19923983, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI7706318, Length=170, Percent_Identity=28.2352941176471, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788459, Length=194, Percent_Identity=34.020618556701, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082160, Length=195, Percent_Identity=31.7948717948718, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI2367175, Length=191, Percent_Identity=34.0314136125654, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787820, Length=251, Percent_Identity=26.6932270916335, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789208, Length=200, Percent_Identity=30, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787335, Length=238, Percent_Identity=27.7310924369748, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786812, Length=176, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082100, Length=199, Percent_Identity=29.6482412060301, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=205, Percent_Identity=29.7560975609756, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=173, Percent_Identity=31.2138728323699, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=204, Percent_Identity=27.9411764705882, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=237, Percent_Identity=28.2700421940928, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=204, Percent_Identity=27.9411764705882, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=179, Percent_Identity=30.1675977653631, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=196, Percent_Identity=29.5918367346939, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=198, Percent_Identity=29.2929292929293, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=216, Percent_Identity=28.7037037037037, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=186, Percent_Identity=28.494623655914, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=172, Percent_Identity=29.0697674418605, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322067, Length=200, Percent_Identity=29, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=27.6041666666667, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24580925, Length=236, Percent_Identity=27.9661016949153, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI116007236, Length=260, Percent_Identity=26.9230769230769, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641232, Length=172, Percent_Identity=31.9767441860465, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI116007238, Length=190, Percent_Identity=28.9473684210526, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24644339, Length=199, Percent_Identity=28.1407035175879, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28571526, Length=200, Percent_Identity=30.5, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21357041, Length=193, Percent_Identity=27.979274611399, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI18859837, Length=271, Percent_Identity=29.1512915129151, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648944, Length=235, Percent_Identity=25.9574468085106, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI23397609, Length=238, Percent_Identity=29.8319327731092, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281364494, Length=171, Percent_Identity=30.4093567251462, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI116007234, Length=252, Percent_Identity=25, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24643142, Length=180, Percent_Identity=32.2222222222222, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641388, Length=256, Percent_Identity=24.609375, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24639444, Length=195, Percent_Identity=30.2564102564103, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26518; Mature: 26387

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATKKIAIVTGAGTGVGRAASLALMQIGYTVVLAGRRLALLQETQTLGEAIGDSLPVQA
CCCCCEEEEEEECCCCCCHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHCCCCCCEE
DMADPASIAALFDTTVKTYGRLDLLFNNAGMGAPPVPFEDLSLAQWQTVVDTNLTAPFLC
CCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHH
TQHAFRIMKDQTPRGGRIINNGSISAHAPRPFSAAYTSTKHAISGLTKASNLDGRAYDIA
HHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEE
VGQIDIGNAATPMTDRMVDGPGVLQPDGSTRHEPRMDAKAVGDAVAYMAALPLDANVLFM
EEEEECCCCCCCCHHHCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
TVMATKMPFVGRG
HHHHHHCCCCCCC
>Mature Secondary Structure 
SATKKIAIVTGAGTGVGRAASLALMQIGYTVVLAGRRLALLQETQTLGEAIGDSLPVQA
CCCCEEEEEEECCCCCCHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHCCCCCCEE
DMADPASIAALFDTTVKTYGRLDLLFNNAGMGAPPVPFEDLSLAQWQTVVDTNLTAPFLC
CCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHH
TQHAFRIMKDQTPRGGRIINNGSISAHAPRPFSAAYTSTKHAISGLTKASNLDGRAYDIA
HHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEE
VGQIDIGNAATPMTDRMVDGPGVLQPDGSTRHEPRMDAKAVGDAVAYMAALPLDANVLFM
EEEEECCCCCCCCHHHCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
TVMATKMPFVGRG
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]