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The map label for this gene is ahpC [C]

Identifier: 86750132

GI number: 86750132

Start: 3438645

End: 3439274

Strand: Direct

Name: ahpC [C]

Synonym: RPB_3015

Alternate gene names: 86750132

Gene position: 3438645-3439274 (Clockwise)

Preceding gene: 86750131

Following gene: 86750133

Centisome position: 64.49

GC content: 62.54

Gene sequence:

>630_bases
ATGTCTCTCCACATCGGCGACACCGCGCCCGATTTCACCGCCGACACCACCCAGGGGCCGATTTCGTTTCACGACTTCAT
CGGCGATTCCTGGGTCTTCTTCTTCAGCCATCCCGCCGACTTCACGCCGGTCTGCACCACCGAGATGGGCAGAACCTCGA
AGCTCGCGCAACAGTTCGCCGCCCGCAACGTCAAGCCGATCGGGCTGTCGACCGACACCGTCGACGAGCACCTCAAATGG
ATCGCGGACGTCAACGACACCCAGCAGACCGATCTGCAATTCCCGATCGTCGCCGACAAGGAGCTGAAGGTCGCCAAGCT
CTACGACATGATCCACCCGAACCAGAGCAACACCGCGGCGGTGCGTTCGGTGTTCATCATCGATCCGAACAAGAAAGTCC
GCCTGACCATGACCTACCCGATGAATGTCGGGCGCAACTTCGACGAGATCCTGCGCGTGATCGATGCGCTGCAGATGGCC
GACAAGTACACCGTCGCCGCGCCGGCCGACTGGCGCCCAGGCGACAAGGTGATCATCCCGCTGTCGCTGCAGGGCGAAGA
CGCCGTGAAGGCATTCCCCCAGGGCTGGGATGCGCCGCGTCCCTATCTGCGCCTGACCACCGTCAAGTAG

Upstream 100 bases:

>100_bases
CCGTTCCCGCTTTCACGGTGCCAAAAAGCGTCGCTACTGTCGGGCTTCCCCGCGCCGCGCGCGGGCTTGCTCATTTCATA
GGCACACAGGAGTTCGATCA

Downstream 100 bases:

>100_bases
CCCGCGGCACCCCACAGTCAGACGGCGCCGGCGGTCGTGACGACGAACGCCGGCGCCGGCCCCGATCGCCACCGCCGCCG
CCGCATCGCGGCCGGCGGGT

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MSLHIGDTAPDFTADTTQGPISFHDFIGDSWVFFFSHPADFTPVCTTEMGRTSKLAQQFAARNVKPIGLSTDTVDEHLKW
IADVNDTQQTDLQFPIVADKELKVAKLYDMIHPNQSNTAAVRSVFIIDPNKKVRLTMTYPMNVGRNFDEILRVIDALQMA
DKYTVAAPADWRPGDKVIIPLSLQGEDAVKAFPQGWDAPRPYLRLTTVK

Sequences:

>Translated_209_residues
MSLHIGDTAPDFTADTTQGPISFHDFIGDSWVFFFSHPADFTPVCTTEMGRTSKLAQQFAARNVKPIGLSTDTVDEHLKW
IADVNDTQQTDLQFPIVADKELKVAKLYDMIHPNQSNTAAVRSVFIIDPNKKVRLTMTYPMNVGRNFDEILRVIDALQMA
DKYTVAAPADWRPGDKVIIPLSLQGEDAVKAFPQGWDAPRPYLRLTTVK
>Mature_208_residues
SLHIGDTAPDFTADTTQGPISFHDFIGDSWVFFFSHPADFTPVCTTEMGRTSKLAQQFAARNVKPIGLSTDTVDEHLKWI
ADVNDTQQTDLQFPIVADKELKVAKLYDMIHPNQSNTAAVRSVFIIDPNKKVRLTMTYPMNVGRNFDEILRVIDALQMAD
KYTVAAPADWRPGDKVIIPLSLQGEDAVKAFPQGWDAPRPYLRLTTVK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=218, Percent_Identity=46.3302752293578, Blast_Score=201, Evalue=5e-52,
Organism=Homo sapiens, GI4505591, Length=185, Percent_Identity=35.1351351351351, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI32455266, Length=185, Percent_Identity=35.1351351351351, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI32455264, Length=185, Percent_Identity=35.1351351351351, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=32.967032967033, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI5453549, Length=157, Percent_Identity=33.1210191082803, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI5802974, Length=161, Percent_Identity=30.4347826086957, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI32483377, Length=161, Percent_Identity=30.4347826086957, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1786822, Length=158, Percent_Identity=27.2151898734177, Blast_Score=68, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25153706, Length=203, Percent_Identity=38.423645320197, Blast_Score=157, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI193204376, Length=191, Percent_Identity=33.5078534031414, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32565831, Length=191, Percent_Identity=33.5078534031414, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17554494, Length=161, Percent_Identity=33.5403726708075, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6319407, Length=214, Percent_Identity=50.4672897196262, Blast_Score=209, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6323613, Length=185, Percent_Identity=29.1891891891892, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320661, Length=161, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24581278, Length=215, Percent_Identity=44.6511627906977, Blast_Score=200, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24652434, Length=203, Percent_Identity=46.3054187192118, Blast_Score=189, Evalue=9e-49,
Organism=Drosophila melanogaster, GI17975518, Length=203, Percent_Identity=46.3054187192118, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24652436, Length=203, Percent_Identity=46.3054187192118, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17157991, Length=160, Percent_Identity=36.25, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24641739, Length=160, Percent_Identity=36.25, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21357347, Length=181, Percent_Identity=30.939226519337, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=31.638418079096, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24656348, Length=161, Percent_Identity=32.9192546583851, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17864676, Length=161, Percent_Identity=32.9192546583851, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23410; Mature: 23279

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHIGDTAPDFTADTTQGPISFHDFIGDSWVFFFSHPADFTPVCTTEMGRTSKLAQQFA
CEEECCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCEECCCCCCHHHHHHHHH
ARNVKPIGLSTDTVDEHLKWIADVNDTQQTDLQFPIVADKELKVAKLYDMIHPNQSNTAA
HCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEECCEEECCCCHHHHHHHHHCCCCCCCEE
VRSVFIIDPNKKVRLTMTYPMNVGRNFDEILRVIDALQMADKYTVAAPADWRPGDKVIIP
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEEE
LSLQGEDAVKAFPQGWDAPRPYLRLTTVK
EEECCCHHHHHCCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
SLHIGDTAPDFTADTTQGPISFHDFIGDSWVFFFSHPADFTPVCTTEMGRTSKLAQQFA
EEECCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCEECCCCCCHHHHHHHHH
ARNVKPIGLSTDTVDEHLKWIADVNDTQQTDLQFPIVADKELKVAKLYDMIHPNQSNTAA
HCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEECCEEECCCCHHHHHHHHHCCCCCCCEE
VRSVFIIDPNKKVRLTMTYPMNVGRNFDEILRVIDALQMADKYTVAAPADWRPGDKVIIP
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEEE
LSLQGEDAVKAFPQGWDAPRPYLRLTTVK
EEECCCHHHHHCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]