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The map label for this gene is 86750006

Identifier: 86750006

GI number: 86750006

Start: 3289286

End: 3289891

Strand: Direct

Name: 86750006

Synonym: RPB_2889

Alternate gene names: NA

Gene position: 3289286-3289891 (Clockwise)

Preceding gene: 86750003

Following gene: 86750013

Centisome position: 61.69

GC content: 70.63

Gene sequence:

>606_bases
ATGATGTCCTCCCGCGTTTCCGCCCCGGCGCCCGGCGCGCTCGGCCCGCCGCTCCGACGGCGTTTCTTCGCGCGCAGCGT
GCACGAGGTGGCACCCGAGCTGATCGGCGCGACGCTGTTAGTCGAGGGTGTCGGCGGCGTCATCGTCGAGGTCGAGGCCT
ATCACCACACCGACCCGGCGGCGCATTCCTACGGCGGGCAGACCGCGCGCAACGCCGTGATGTTCGGTCCGCCCGGATTC
GCCTATGTGTATCGCTCCTACGGCATCCATTGGTGCGTCAATGTCGTCTGCGAGGCGGAGGGCTCGGCCAGCGCCGTGCT
GATCCGCGCGCTGCAGCCGACCCACGGGGTGGAAGCGATGCGCGCCCGCCGCGGCCTCGACGACGCGCGCAGCCTCTGTT
CCGGCCCCGGCAAGCTGGCCCAGGCGCTCGGCATCAGCATCGCCCACAACGGCCTGCCACTCGACGCCCCGCCATTCGCG
ATCCATCGCCGGATCGGCGAGCCGGACATCGTCACCGGCCCGCGCATCGGCATCACCAAGGCGGCGGACTATCCGTGGCG
GTTCGGGCTGAAGGGGTCGCGGTTCGTCAGCGTCCCCTTCAAATAG

Upstream 100 bases:

>100_bases
ACCCGGGCTGCTTGCGGGCGCTTATCCCTTGGAATAATGCTCGATTTCTCGGCATTCCGGCGGCGCGCGGCGCTGCCCGC
CCTCGCGAGCCCTCGGCCCC

Downstream 100 bases:

>100_bases
CCGATCATTCGCACCGCCTGCGCCACGACCGCCCCGGCGACCGTCCGAAAGATCACCGCGGCTAAAATGGAATATTGGCG
ATCTGCCCGGTCAACTCCTG

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MMSSRVSAPAPGALGPPLRRRFFARSVHEVAPELIGATLLVEGVGGVIVEVEAYHHTDPAAHSYGGQTARNAVMFGPPGF
AYVYRSYGIHWCVNVVCEAEGSASAVLIRALQPTHGVEAMRARRGLDDARSLCSGPGKLAQALGISIAHNGLPLDAPPFA
IHRRIGEPDIVTGPRIGITKAADYPWRFGLKGSRFVSVPFK

Sequences:

>Translated_201_residues
MMSSRVSAPAPGALGPPLRRRFFARSVHEVAPELIGATLLVEGVGGVIVEVEAYHHTDPAAHSYGGQTARNAVMFGPPGF
AYVYRSYGIHWCVNVVCEAEGSASAVLIRALQPTHGVEAMRARRGLDDARSLCSGPGKLAQALGISIAHNGLPLDAPPFA
IHRRIGEPDIVTGPRIGITKAADYPWRFGLKGSRFVSVPFK
>Mature_201_residues
MMSSRVSAPAPGALGPPLRRRFFARSVHEVAPELIGATLLVEGVGGVIVEVEAYHHTDPAAHSYGGQTARNAVMFGPPGF
AYVYRSYGIHWCVNVVCEAEGSASAVLIRALQPTHGVEAMRARRGLDDARSLCSGPGKLAQALGISIAHNGLPLDAPPFA
IHRRIGEPDIVTGPRIGITKAADYPWRFGLKGSRFVSVPFK

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=173, Percent_Identity=42.7745664739884, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI62632765, Length=173, Percent_Identity=42.7745664739884, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI62632771, Length=173, Percent_Identity=42.7745664739884, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_RHOP2 (Q2IW19)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_486502.1
- ProteinModelPortal:   Q2IW19
- SMR:   Q2IW19
- STRING:   Q2IW19
- GeneID:   3910683
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_2889
- eggNOG:   COG2094
- HOGENOM:   HBG664239
- OMA:   LCSGPGK
- ProtClustDB:   PRK00802
- BioCyc:   RPAL316058:RPB_2889-MONOMER
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.21

Molecular weight: Translated: 21389; Mature: 21389

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSRVSAPAPGALGPPLRRRFFARSVHEVAPELIGATLLVEGVGGVIVEVEAYHHTDPA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEEECCCCC
AHSYGGQTARNAVMFGPPGFAYVYRSYGIHWCVNVVCEAEGSASAVLIRALQPTHGVEAM
HHHCCCCCCCCEEEECCCCHHHHHHHCCHHEEEEEEECCCCCCCEEEEEECCCCCCHHHH
RARRGLDDARSLCSGPGKLAQALGISIAHNGLPLDAPPFAIHRRIGEPDIVTGPRIGITK
HHHCCCHHHHHHHCCHHHHHHHHHHEHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCC
AADYPWRFGLKGSRFVSVPFK
CCCCCEEECCCCCEEEECCCC
>Mature Secondary Structure
MMSSRVSAPAPGALGPPLRRRFFARSVHEVAPELIGATLLVEGVGGVIVEVEAYHHTDPA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEEECCCCC
AHSYGGQTARNAVMFGPPGFAYVYRSYGIHWCVNVVCEAEGSASAVLIRALQPTHGVEAM
HHHCCCCCCCCEEEECCCCHHHHHHHCCHHEEEEEEECCCCCCCEEEEEECCCCCCHHHH
RARRGLDDARSLCSGPGKLAQALGISIAHNGLPLDAPPFAIHRRIGEPDIVTGPRIGITK
HHHCCCHHHHHHHCCHHHHHHHHHHEHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCC
AADYPWRFGLKGSRFVSVPFK
CCCCCEEECCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA