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The map label for this gene is fmt [H]

Identifier: 86749978

GI number: 86749978

Start: 3263280

End: 3263870

Strand: Direct

Name: fmt [H]

Synonym: RPB_2861

Alternate gene names: 86749978

Gene position: 3263280-3263870 (Clockwise)

Preceding gene: 86749977

Following gene: 86749979

Centisome position: 61.21

GC content: 71.07

Gene sequence:

>591_bases
ATGCGCATCACCCTCGTCGGCTCGCGACATTTCGGCGTGGCCACCCTGGAGATGCTGCGCAGCCGCGGCATCGCGGTGCC
GCGCGTGGTTGTGGCGGACGGCGGCGACCGGCTGGCGCTAGCGGCCGAGACGGCCGGGATTGCGGTGACGGTGCAGGCCA
GCCCGAAGCTCGTCACCGCCGCGGAGATCGCACCGGACACTGATCTGATCGTCGCCGCGCACTGCCACGCCCGGGTCGAT
CGCGACGCGCTGGCGGCGGCCCGGCTCGGCGGCATCGGCTATCACCCGTCGCTGCTGCCGCGGCATCGCGGCATCGCCGC
GGTGGAATGGACCATCCGCGAGGGCGATCCGATCGCCGGCGGCACGGTCTATCACCTCGCCGACCGGATGGATGCCGGTG
CGATCGCGCTGCAGGAATGGTGCTTCGTGCACAAGGGCGAAACCGCCCGCGAATTGTGGGAGCGCGTGCTGGCGCCGCTC
GGGATCAAACTGCTGGCGCAGGTGATCGACCACGCCCGCACCCATGCGGAACTGCCGGCGCAGCCGCAAGACGAGCGATT
CGCCACGCGAGCGCCCCGAACGACAATGTGA

Upstream 100 bases:

>100_bases
ATCATGGGGTCGAGGGTTCGAGTCCCTCCGCGCTCACCACACTGACCGATTCCGGTGCAGTCGCTTCGCCCATCCCGATC
CTCCTCGGACCACAGAGTTC

Downstream 100 bases:

>100_bases
CGCAAGCCGGATCGCCATCTCGATACCGGCCACCACCAAATCTACGACTTTCGTACTCACGAAAAATTGTTCCTGCGCAA
TGTGGCCGCCCCCGCTCGCG

Product: Formyl transferase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MRITLVGSRHFGVATLEMLRSRGIAVPRVVVADGGDRLALAAETAGIAVTVQASPKLVTAAEIAPDTDLIVAAHCHARVD
RDALAAARLGGIGYHPSLLPRHRGIAAVEWTIREGDPIAGGTVYHLADRMDAGAIALQEWCFVHKGETARELWERVLAPL
GIKLLAQVIDHARTHAELPAQPQDERFATRAPRTTM

Sequences:

>Translated_196_residues
MRITLVGSRHFGVATLEMLRSRGIAVPRVVVADGGDRLALAAETAGIAVTVQASPKLVTAAEIAPDTDLIVAAHCHARVD
RDALAAARLGGIGYHPSLLPRHRGIAAVEWTIREGDPIAGGTVYHLADRMDAGAIALQEWCFVHKGETARELWERVLAPL
GIKLLAQVIDHARTHAELPAQPQDERFATRAPRTTM
>Mature_196_residues
MRITLVGSRHFGVATLEMLRSRGIAVPRVVVADGGDRLALAAETAGIAVTVQASPKLVTAAEIAPDTDLIVAAHCHARVD
RDALAAARLGGIGYHPSLLPRHRGIAAVEWTIREGDPIAGGTVYHLADRMDAGAIALQEWCFVHKGETARELWERVLAPL
GIKLLAQVIDHARTHAELPAQPQDERFATRAPRTTM

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=200, Percent_Identity=34.5, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI21614513, Length=201, Percent_Identity=34.8258706467662, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI133930964, Length=212, Percent_Identity=31.1320754716981, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24585660, Length=208, Percent_Identity=31.25, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 21047; Mature: 21047

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITLVGSRHFGVATLEMLRSRGIAVPRVVVADGGDRLALAAETAGIAVTVQASPKLVTA
CEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCEEEEEECCCCEEEE
AEIAPDTDLIVAAHCHARVDRDALAAARLGGIGYHPSLLPRHRGIAAVEWTIREGDPIAG
EECCCCCCEEEEEEHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCC
GTVYHLADRMDAGAIALQEWCFVHKGETARELWERVLAPLGIKLLAQVIDHARTHAELPA
CHHEEHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QPQDERFATRAPRTTM
CCCCCHHHHCCCCCCC
>Mature Secondary Structure
MRITLVGSRHFGVATLEMLRSRGIAVPRVVVADGGDRLALAAETAGIAVTVQASPKLVTA
CEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCEEEEEECCCCEEEE
AEIAPDTDLIVAAHCHARVDRDALAAARLGGIGYHPSLLPRHRGIAAVEWTIREGDPIAG
EECCCCCCEEEEEEHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCC
GTVYHLADRMDAGAIALQEWCFVHKGETARELWERVLAPLGIKLLAQVIDHARTHAELPA
CHHEEHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QPQDERFATRAPRTTM
CCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA