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The map label for this gene is kup1 [H]

Identifier: 86749632

GI number: 86749632

Start: 2872384

End: 2874246

Strand: Direct

Name: kup1 [H]

Synonym: RPB_2512

Alternate gene names: 86749632

Gene position: 2872384-2874246 (Clockwise)

Preceding gene: 86749631

Following gene: 86749635

Centisome position: 53.87

GC content: 65.75

Gene sequence:

>1863_bases
ATGAGCCAGCACAAGAACAGCGTCGGGCTGCTGGTCAGCGCGGTCGGCGTCGTCTTCGGCGACATCGGCACCAGCCCGCT
CTACGCCATGAAGGAGACTTTCGCCGGTCATCACCCGATCATGGTGTCGCCGGAGAACATCTTCGGCGTGTTGTCGCTGG
TGTTCTGGACGGTGATGCTGCTGGTCACGGTGAAATACGTGATCCTGATCATGCGTGCCGACAACCACGGCGAAGGCGGC
AGCCTCGCGCTGCTGGCGCTGGTGACCGAGCTGACGCGCGGGCGGCGCGTGCACTATCCGTTGATGCTGCTCGGCGTGAT
CGCCGCGGCGCTGTTTTACGGCGACAGTATGATCACGCCGGCGATCTCGGTGCTCAGCGCGGTCGAGGGGCTCGAAGTCG
TGACGCCCGACCTGAAGGCGTATGTCGTGCCGATCACCGCGCTGGTGCTGACCGGCCTGTTCGCGATCCAGTCGCGCGGA
ACCGCGCTGGTCGGTCGCCTGTTCGGGCCGGTGATGTGCCTGTGGTTCGTCACGCTGGCGCTGCTCGGCATCGCCAACAT
CGTCCGTGCGCCGGAAGTGCTGGAGGCGATCAGTCCGACCTTCGCGATCGAATTCGTCATCCGTCATCCGCTGATGAGTT
TCTACGCGCTCGGCACCGTCGTGCTGGCCGTCACCGGCGGTGAAGCGCTGTACACCGACATGGGCCATTTCGGCCGGTTT
CCGATCCGGCTGGGGTGGTTCAGCCTGGTGCTGCCGGCGCTGCTGCTGAACTATTTCGGCCAGGGCGCGCTGCTGATCGC
CGACCCCGCCGCGATCCAGAATCCGTTCTTCCGGATGGGGCCGGAATGGATGGTGATGCCGATGGTCGCGCTGGCGACGC
TGGCCACCGTGATCGCGTCGCAGGCGGTGATCTCCGGCGCGTTCTCGGTGGCGCGGCAGGCGATCCAGCTCGGCCTGCTG
CCGCGGATGACGATCGTGCACACCTCGGGCGAGGAGGCTGGCCAGATCTACGTGCCGTTCACCAACTGGACCTTGTACTT
CGCCGTGATGGCGCTGGTGATCGGCTTCCAGTCGTCGAGCAATCTGGCGGCCGCCTACGGCATCGCCGTCACCGGCACGA
TGATGATCGACACCATCCTGGTGTCGTTCGTGATGGCGCTGCTGTGGCGCTGGAACATGGCGCTGGTGATCGTGGTGGCG
GGCACGCTGCTGCTGGTCGATTTCGCGTATTTCGCCGCCAACATCATCAAGGTGGCGCAGGGCGGCTGGTTCCCGCTGTT
CATCGGCTTCATCTCGTTCACGGTGCTGACGACGTGGCGGCGCGGGCGCGCGCTGGTGCGCAAGCAGCTCAAGAAGCAGG
CGGTGCCGCTCGACGTGGTGCTGCGCGCGCTCGGGCCCAACGTGTCGCGGGCACGCGGCACCGCGGTGTTCCTGACCGCC
GCGACCGACGGCGTGCCGCCGGCGCTGCTGCACAATCTCAAGCACAACCAGACCGTCCACCAGCGCGTCGTGCTGGCGAC
CGTGACCACCGCGGAGACGCCCTATGTGCCCGACAGCGAGCGCGTGCACATGACCGATATCGGCGACGGCTTCCATCGCC
TGATCATCCGCTACGGTTTCATGCAGACCCCCGACATTCCGGCGGCGCTGACGCTGTGCAAGCAGTTCGGCCACGAGTTC
AACATGATGTCGACCTCGTTCTTTCTCAGCCGCGAGACCTTCGTGCCGAGCCTCAATCCCGGCATGGCGCTGTGGCGCGA
GCGGCTGTTCACCTTCATGACGCTGAACGCGACGCGGGCCACGACCTTCTTCAAGATCCCGACCGACCGCGTCGTCGAAC
TCGGAACCCAGCTCGAGATCTGA

Upstream 100 bases:

>100_bases
TGACCGGGGCGATGCGGCATGGCTCTCGGCCCGGCGTCGCCGCGGCGCGCCCGATGCCTGTCGTCCCCGCAGACCGGTCG
ATGCGGGCCGGGGGGCGCGC

Downstream 100 bases:

>100_bases
TCGGGGCGGCGCGCGCCACAAAGACGGGCCGGCCCGCGTGGCAGGCGCGCTGCGCTCAGGCCAGTCCGAGCGCGAAGGCC
AGCGTGCCGATCGCGGCATG

Product: K+ potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MSQHKNSVGLLVSAVGVVFGDIGTSPLYAMKETFAGHHPIMVSPENIFGVLSLVFWTVMLLVTVKYVILIMRADNHGEGG
SLALLALVTELTRGRRVHYPLMLLGVIAAALFYGDSMITPAISVLSAVEGLEVVTPDLKAYVVPITALVLTGLFAIQSRG
TALVGRLFGPVMCLWFVTLALLGIANIVRAPEVLEAISPTFAIEFVIRHPLMSFYALGTVVLAVTGGEALYTDMGHFGRF
PIRLGWFSLVLPALLLNYFGQGALLIADPAAIQNPFFRMGPEWMVMPMVALATLATVIASQAVISGAFSVARQAIQLGLL
PRMTIVHTSGEEAGQIYVPFTNWTLYFAVMALVIGFQSSSNLAAAYGIAVTGTMMIDTILVSFVMALLWRWNMALVIVVA
GTLLLVDFAYFAANIIKVAQGGWFPLFIGFISFTVLTTWRRGRALVRKQLKKQAVPLDVVLRALGPNVSRARGTAVFLTA
ATDGVPPALLHNLKHNQTVHQRVVLATVTTAETPYVPDSERVHMTDIGDGFHRLIIRYGFMQTPDIPAALTLCKQFGHEF
NMMSTSFFLSRETFVPSLNPGMALWRERLFTFMTLNATRATTFFKIPTDRVVELGTQLEI

Sequences:

>Translated_620_residues
MSQHKNSVGLLVSAVGVVFGDIGTSPLYAMKETFAGHHPIMVSPENIFGVLSLVFWTVMLLVTVKYVILIMRADNHGEGG
SLALLALVTELTRGRRVHYPLMLLGVIAAALFYGDSMITPAISVLSAVEGLEVVTPDLKAYVVPITALVLTGLFAIQSRG
TALVGRLFGPVMCLWFVTLALLGIANIVRAPEVLEAISPTFAIEFVIRHPLMSFYALGTVVLAVTGGEALYTDMGHFGRF
PIRLGWFSLVLPALLLNYFGQGALLIADPAAIQNPFFRMGPEWMVMPMVALATLATVIASQAVISGAFSVARQAIQLGLL
PRMTIVHTSGEEAGQIYVPFTNWTLYFAVMALVIGFQSSSNLAAAYGIAVTGTMMIDTILVSFVMALLWRWNMALVIVVA
GTLLLVDFAYFAANIIKVAQGGWFPLFIGFISFTVLTTWRRGRALVRKQLKKQAVPLDVVLRALGPNVSRARGTAVFLTA
ATDGVPPALLHNLKHNQTVHQRVVLATVTTAETPYVPDSERVHMTDIGDGFHRLIIRYGFMQTPDIPAALTLCKQFGHEF
NMMSTSFFLSRETFVPSLNPGMALWRERLFTFMTLNATRATTFFKIPTDRVVELGTQLEI
>Mature_619_residues
SQHKNSVGLLVSAVGVVFGDIGTSPLYAMKETFAGHHPIMVSPENIFGVLSLVFWTVMLLVTVKYVILIMRADNHGEGGS
LALLALVTELTRGRRVHYPLMLLGVIAAALFYGDSMITPAISVLSAVEGLEVVTPDLKAYVVPITALVLTGLFAIQSRGT
ALVGRLFGPVMCLWFVTLALLGIANIVRAPEVLEAISPTFAIEFVIRHPLMSFYALGTVVLAVTGGEALYTDMGHFGRFP
IRLGWFSLVLPALLLNYFGQGALLIADPAAIQNPFFRMGPEWMVMPMVALATLATVIASQAVISGAFSVARQAIQLGLLP
RMTIVHTSGEEAGQIYVPFTNWTLYFAVMALVIGFQSSSNLAAAYGIAVTGTMMIDTILVSFVMALLWRWNMALVIVVAG
TLLLVDFAYFAANIIKVAQGGWFPLFIGFISFTVLTTWRRGRALVRKQLKKQAVPLDVVLRALGPNVSRARGTAVFLTAA
TDGVPPALLHNLKHNQTVHQRVVLATVTTAETPYVPDSERVHMTDIGDGFHRLIIRYGFMQTPDIPAALTLCKQFGHEFN
MMSTSFFLSRETFVPSLNPGMALWRERLFTFMTLNATRATTFFKIPTDRVVELGTQLEI

Specific function: Transport of potassium into the cell [H]

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family [H]

Homologues:

Organism=Escherichia coli, GI48994960, Length=622, Percent_Identity=47.588424437299, Blast_Score=598, Evalue=1e-172,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003855
- InterPro:   IPR023051 [H]

Pfam domain/function: PF02705 K_trans [H]

EC number: NA

Molecular weight: Translated: 67629; Mature: 67498

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQHKNSVGLLVSAVGVVFGDIGTSPLYAMKETFAGHHPIMVSPENIFGVLSLVFWTVML
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHH
LVTVKYVILIMRADNHGEGGSLALLALVTELTRGRRVHYPLMLLGVIAAALFYGDSMITP
HHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHCCHHHHH
AISVLSAVEGLEVVTPDLKAYVVPITALVLTGLFAIQSRGTALVGRLFGPVMCLWFVTLA
HHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LLGIANIVRAPEVLEAISPTFAIEFVIRHPLMSFYALGTVVLAVTGGEALYTDMGHFGRF
HHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCHHCCCCC
PIRLGWFSLVLPALLLNYFGQGALLIADPAAIQNPFFRMGPEWMVMPMVALATLATVIAS
CHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHH
QAVISGAFSVARQAIQLGLLPRMTIVHTSGEEAGQIYVPFTNWTLYFAVMALVIGFQSSS
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCC
NLAAAYGIAVTGTMMIDTILVSFVMALLWRWNMALVIVVAGTLLLVDFAYFAANIIKVAQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGWFPLFIGFISFTVLTTWRRGRALVRKQLKKQAVPLDVVLRALGPNVSRARGTAVFLTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEEE
ATDGVPPALLHNLKHNQTVHQRVVLATVTTAETPYVPDSERVHMTDIGDGFHRLIIRYGF
CCCCCCHHHHHHCCCCHHHHHHEEEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHCC
MQTPDIPAALTLCKQFGHEFNMMSTSFFLSRETFVPSLNPGMALWRERLFTFMTLNATRA
CCCCCCHHHHHHHHHHCCHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCC
TTFFKIPTDRVVELGTQLEI
EEEEECCHHHHHHCCCCCCC
>Mature Secondary Structure 
SQHKNSVGLLVSAVGVVFGDIGTSPLYAMKETFAGHHPIMVSPENIFGVLSLVFWTVML
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHH
LVTVKYVILIMRADNHGEGGSLALLALVTELTRGRRVHYPLMLLGVIAAALFYGDSMITP
HHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHCCHHHHH
AISVLSAVEGLEVVTPDLKAYVVPITALVLTGLFAIQSRGTALVGRLFGPVMCLWFVTLA
HHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LLGIANIVRAPEVLEAISPTFAIEFVIRHPLMSFYALGTVVLAVTGGEALYTDMGHFGRF
HHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCHHCCCCC
PIRLGWFSLVLPALLLNYFGQGALLIADPAAIQNPFFRMGPEWMVMPMVALATLATVIAS
CHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHH
QAVISGAFSVARQAIQLGLLPRMTIVHTSGEEAGQIYVPFTNWTLYFAVMALVIGFQSSS
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCC
NLAAAYGIAVTGTMMIDTILVSFVMALLWRWNMALVIVVAGTLLLVDFAYFAANIIKVAQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGWFPLFIGFISFTVLTTWRRGRALVRKQLKKQAVPLDVVLRALGPNVSRARGTAVFLTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEEE
ATDGVPPALLHNLKHNQTVHQRVVLATVTTAETPYVPDSERVHMTDIGDGFHRLIIRYGF
CCCCCCHHHHHHCCCCHHHHHHEEEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHCC
MQTPDIPAALTLCKQFGHEFNMMSTSFFLSRETFVPSLNPGMALWRERLFTFMTLNATRA
CCCCCCHHHHHHHHHHCCHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCC
TTFFKIPTDRVVELGTQLEI
EEEEECCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA