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The map label for this gene is atoS [C]

Identifier: 86749269

GI number: 86749269

Start: 2437388

End: 2439355

Strand: Reverse

Name: atoS [C]

Synonym: RPB_2148

Alternate gene names: 86749269

Gene position: 2439355-2437388 (Counterclockwise)

Preceding gene: 86749272

Following gene: 86749268

Centisome position: 45.75

GC content: 68.75

Gene sequence:

>1968_bases
ATGACGCCGACAAGCACGCAATGTCGCGAGACACGCGAAGTCCACCCGCACAGACGCGATGACGAAACGATGAGCTTCGA
CAATGCCAGTGCTTCACTCCTCAGGGCGCTGGTTCATGCGGCCCCCGACGGCATCTTCCTGGTCGATCGCCATCAGCGCA
TCGCGCTGTTCAACCCCGCTTGCGAGGGGCTGTTCGGCTGGTCGGCCCGCGAGGCGCTCGGCGAAGACGTCGCCACGCTG
ATTCCGGACTGGCGGCAGCAGCCGGCACTCCGGTCGCAGGTGCAGGCCCGGCGCCGGGACGGCACCACGTTGACCGTCAC
GCTGGCCACGGCCGCCTCGGCCGCCGATGCCGCGTCGATCGTTGCGACGGTGCGTGAACGCGACATCACCGAGCAGAGTC
GCGCCGAACGCGCGATCCGCGAGGCCGACGCGCGCGTCGCGACGCTGATCCAGACCGTGGACAACGGCGTGATCCTCACC
GACCGGCTCGGCCGGATCAAGACCTTCAACCTCGCCTGCCGCAGGCTGTTCGGCTACCAGGCCGACGAGGTGATCGACCG
GCACATCTCGATGCTGGCCCCGGCGGCGAACGCCGACGCGATCCAATCGCTCCTTCGCCGCGGCAACCAGGCCGACGAGC
ACGGCCGGATCGGCACCGTCCGCGGCATGACCGGGCTGCGCCGCGACGGCGGGACGTTTCCGATGGAGCTGTCTGCCGGC
ACGACCGTGCAGGACGGCGAGCCGGTGTTCGTGGTCGCGATCCAAGACCTCACCGACCGCAAGCACACCGAAGAACGACT
GGCGCAGGCGCAGAAGATGGAGATCGTCGGCCAGCTCTCCGGCGGCATCGCGCACGACTTCAACAACCTGCTGACCGTGA
TCGTCGGCAACGCCGAATTTCTCGCCGACCAGCTCAAGGCGCGGCAGGATCTGCGCGGGCTGGCCTGCGAGATCAGCCGC
GCCGGCCAGCGCGGCGCCGAACTGACGCAGCGCCTGCTCGCGTTCAGCCGCCGGCAGACGCTGAAGCCGGTCGCGGTCGA
CTGCAACGAGCTGGTCTCGTCGATGCACGATCTGCTGCGCCGGACGCTGCGCGAAGACATCGTCATCGACATCGCGTTCG
GGGCCGAGCTCTGCGCCGCCTTCGCCGATCCCGCGCAGCTCGAATCCGCGATCCTCAACCTGTCGCTGAACGCGCAGGAC
GCGATGCTCGGCGGCGGCCGGCTCAGCATCACCACCGCCAACGTCACGCTCGACGCCTCGTATCAATCGCTCAACCAGGA
CGTCCGTCCCGGCGACTACGTGCTGATCGCGATCACCGACAACGGCTCGGGAATGTCGAAGGAGGTGCTCGATCGCGTGT
TCGAGCCGTTCTACACGACCAAGGAGGTCGGCAAGGGCTCCGGCCTCGGACTCAGCATGGTGTACGGTTTCGTCAAGCAG
TCGAACGGCCACGTCTCGCTCTACAGCGAGCCCGGGCTCGGCACCACGGTGCGACTGTATCTCCCCGCGGTCGCCGCCGG
CCGGCCGACCGGCCCGGAGCGGCCGGACTCCGTGGAGCGCCTCGCGTCGCGCGGCGAAGTCGTGCTGATCGTCGAGGACG
ATCCGTTCGTCCGGTCCTACGCGGTGATGTGCCTGCGCAGCCTGGGCTACGGCGTGATCGCCGCATCCGACGGCGCAGGC
GCGCTGCAGACGCTCGACGACGACACCCATTTCGACATCCTGTTCACCGATGTCGTGATGCCCGGCGGCATCAGCGGCTG
GGAGCTCGCCGAGACCGCGTCGCGCCGACGGCCGGATCTGAGGGTGCTGCTGACCTCCGGCTACGCGCTCGAGACGATCG
CCGGGCGGAGCCACGGCCGCGAGCATCTGGCGATCCTGACCAAGCCGTACCGCAAGGCGGACCTCGCGCGAAAGCTGCGC
GAGGTGGTCGAATCCTCGCCGCCGGCTGCCATCTGCCGCGAATGCTAA

Upstream 100 bases:

>100_bases
CGACACGCAGGCGACGCTGTATTTTTTTATCGATTTGAACGAAGCGCCACCACAACGACGCGACATACACACGACGCGAC
ACACACGACGCGATACGCAC

Downstream 100 bases:

>100_bases
CGGGTCGTTAACCCTGAGCATCCTACGGTTGCGGAATATTTCGTTTCCGGCCGGACAGCGGACTCCCGTGTTGTTGCAAA
AGCAAACCATACAGCCGGCA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 655; Mature: 654

Protein sequence:

>655_residues
MTPTSTQCRETREVHPHRRDDETMSFDNASASLLRALVHAAPDGIFLVDRHQRIALFNPACEGLFGWSAREALGEDVATL
IPDWRQQPALRSQVQARRRDGTTLTVTLATAASAADAASIVATVRERDITEQSRAERAIREADARVATLIQTVDNGVILT
DRLGRIKTFNLACRRLFGYQADEVIDRHISMLAPAANADAIQSLLRRGNQADEHGRIGTVRGMTGLRRDGGTFPMELSAG
TTVQDGEPVFVVAIQDLTDRKHTEERLAQAQKMEIVGQLSGGIAHDFNNLLTVIVGNAEFLADQLKARQDLRGLACEISR
AGQRGAELTQRLLAFSRRQTLKPVAVDCNELVSSMHDLLRRTLREDIVIDIAFGAELCAAFADPAQLESAILNLSLNAQD
AMLGGGRLSITTANVTLDASYQSLNQDVRPGDYVLIAITDNGSGMSKEVLDRVFEPFYTTKEVGKGSGLGLSMVYGFVKQ
SNGHVSLYSEPGLGTTVRLYLPAVAAGRPTGPERPDSVERLASRGEVVLIVEDDPFVRSYAVMCLRSLGYGVIAASDGAG
ALQTLDDDTHFDILFTDVVMPGGISGWELAETASRRRPDLRVLLTSGYALETIAGRSHGREHLAILTKPYRKADLARKLR
EVVESSPPAAICREC

Sequences:

>Translated_655_residues
MTPTSTQCRETREVHPHRRDDETMSFDNASASLLRALVHAAPDGIFLVDRHQRIALFNPACEGLFGWSAREALGEDVATL
IPDWRQQPALRSQVQARRRDGTTLTVTLATAASAADAASIVATVRERDITEQSRAERAIREADARVATLIQTVDNGVILT
DRLGRIKTFNLACRRLFGYQADEVIDRHISMLAPAANADAIQSLLRRGNQADEHGRIGTVRGMTGLRRDGGTFPMELSAG
TTVQDGEPVFVVAIQDLTDRKHTEERLAQAQKMEIVGQLSGGIAHDFNNLLTVIVGNAEFLADQLKARQDLRGLACEISR
AGQRGAELTQRLLAFSRRQTLKPVAVDCNELVSSMHDLLRRTLREDIVIDIAFGAELCAAFADPAQLESAILNLSLNAQD
AMLGGGRLSITTANVTLDASYQSLNQDVRPGDYVLIAITDNGSGMSKEVLDRVFEPFYTTKEVGKGSGLGLSMVYGFVKQ
SNGHVSLYSEPGLGTTVRLYLPAVAAGRPTGPERPDSVERLASRGEVVLIVEDDPFVRSYAVMCLRSLGYGVIAASDGAG
ALQTLDDDTHFDILFTDVVMPGGISGWELAETASRRRPDLRVLLTSGYALETIAGRSHGREHLAILTKPYRKADLARKLR
EVVESSPPAAICREC
>Mature_654_residues
TPTSTQCRETREVHPHRRDDETMSFDNASASLLRALVHAAPDGIFLVDRHQRIALFNPACEGLFGWSAREALGEDVATLI
PDWRQQPALRSQVQARRRDGTTLTVTLATAASAADAASIVATVRERDITEQSRAERAIREADARVATLIQTVDNGVILTD
RLGRIKTFNLACRRLFGYQADEVIDRHISMLAPAANADAIQSLLRRGNQADEHGRIGTVRGMTGLRRDGGTFPMELSAGT
TVQDGEPVFVVAIQDLTDRKHTEERLAQAQKMEIVGQLSGGIAHDFNNLLTVIVGNAEFLADQLKARQDLRGLACEISRA
GQRGAELTQRLLAFSRRQTLKPVAVDCNELVSSMHDLLRRTLREDIVIDIAFGAELCAAFADPAQLESAILNLSLNAQDA
MLGGGRLSITTANVTLDASYQSLNQDVRPGDYVLIAITDNGSGMSKEVLDRVFEPFYTTKEVGKGSGLGLSMVYGFVKQS
NGHVSLYSEPGLGTTVRLYLPAVAAGRPTGPERPDSVERLASRGEVVLIVEDDPFVRSYAVMCLRSLGYGVIAASDGAGA
LQTLDDDTHFDILFTDVVMPGGISGWELAETASRRRPDLRVLLTSGYALETIAGRSHGREHLAILTKPYRKADLARKLRE
VVESSPPAAICREC

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=389, Percent_Identity=29.305912596401, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=30.8, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081816, Length=370, Percent_Identity=25.1351351351351, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788713, Length=361, Percent_Identity=26.5927977839335, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71237; Mature: 71105

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTSTQCRETREVHPHRRDDETMSFDNASASLLRALVHAAPDGIFLVDRHQRIALFNPA
CCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEEECHH
CEGLFGWSAREALGEDVATLIPDWRQQPALRSQVQARRRDGTTLTVTLATAASAADAASI
HHCCCCCHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHH
VATVRERDITEQSRAERAIREADARVATLIQTVDNGVILTDRLGRIKTFNLACRRLFGYQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHCCC
ADEVIDRHISMLAPAANADAIQSLLRRGNQADEHGRIGTVRGMTGLRRDGGTFPMELSAG
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCC
TTVQDGEPVFVVAIQDLTDRKHTEERLAQAQKMEIVGQLSGGIAHDFNNLLTVIVGNAEF
CEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCEEEEEECCHHH
LADQLKARQDLRGLACEISRAGQRGAELTQRLLAFSRRQTLKPVAVDCNELVSSMHDLLR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHH
RTLREDIVIDIAFGAELCAAFADPAQLESAILNLSLNAQDAMLGGGRLSITTANVTLDAS
HHHHHCEEEEEEHHHHHHHHHCCHHHHHHHHHEEECCCCHHEECCCEEEEEEEEEEEECC
YQSLNQDVRPGDYVLIAITDNGSGMSKEVLDRVFEPFYTTKEVGKGSGLGLSMVYGFVKQ
HHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
SNGHVSLYSEPGLGTTVRLYLPAVAAGRPTGPERPDSVERLASRGEVVLIVEDDPFVRSY
CCCCEEEEECCCCCCEEEEEECHHHCCCCCCCCCCHHHHHHHCCCCEEEEECCCCHHHHH
AVMCLRSLGYGVIAASDGAGALQTLDDDTHFDILFTDVVMPGGISGWELAETASRRRPDL
HHHHHHHCCCCEEEECCCCCCHHCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCE
RVLLTSGYALETIAGRSHGREHLAILTKPYRKADLARKLREVVESSPPAAICREC
EEEEECCCEEEHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure 
TPTSTQCRETREVHPHRRDDETMSFDNASASLLRALVHAAPDGIFLVDRHQRIALFNPA
CCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEEECHH
CEGLFGWSAREALGEDVATLIPDWRQQPALRSQVQARRRDGTTLTVTLATAASAADAASI
HHCCCCCHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHH
VATVRERDITEQSRAERAIREADARVATLIQTVDNGVILTDRLGRIKTFNLACRRLFGYQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHCCC
ADEVIDRHISMLAPAANADAIQSLLRRGNQADEHGRIGTVRGMTGLRRDGGTFPMELSAG
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCC
TTVQDGEPVFVVAIQDLTDRKHTEERLAQAQKMEIVGQLSGGIAHDFNNLLTVIVGNAEF
CEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCEEEEEECCHHH
LADQLKARQDLRGLACEISRAGQRGAELTQRLLAFSRRQTLKPVAVDCNELVSSMHDLLR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHH
RTLREDIVIDIAFGAELCAAFADPAQLESAILNLSLNAQDAMLGGGRLSITTANVTLDAS
HHHHHCEEEEEEHHHHHHHHHCCHHHHHHHHHEEECCCCHHEECCCEEEEEEEEEEEECC
YQSLNQDVRPGDYVLIAITDNGSGMSKEVLDRVFEPFYTTKEVGKGSGLGLSMVYGFVKQ
HHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
SNGHVSLYSEPGLGTTVRLYLPAVAAGRPTGPERPDSVERLASRGEVVLIVEDDPFVRSY
CCCCEEEEECCCCCCEEEEEECHHHCCCCCCCCCCHHHHHHHCCCCEEEEECCCCHHHHH
AVMCLRSLGYGVIAASDGAGALQTLDDDTHFDILFTDVVMPGGISGWELAETASRRRPDL
HHHHHHHCCCCEEEECCCCCCHHCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCE
RVLLTSGYALETIAGRSHGREHLAILTKPYRKADLARKLREVVESSPPAAICREC
EEEEECCCEEEHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA