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The map label for this gene is tnaA [H]

Identifier: 86749089

GI number: 86749089

Start: 2233824

End: 2235272

Strand: Direct

Name: tnaA [H]

Synonym: RPB_1966

Alternate gene names: 86749089

Gene position: 2233824-2235272 (Clockwise)

Preceding gene: 86749086

Following gene: 86749090

Centisome position: 41.9

GC content: 64.53

Gene sequence:

>1449_bases
ATGGCGACGGTGAAGTTCTACGGCAACGAGACGGTGCCGCTCGAGATGCACAAGGTGCGGATCGTGCAGAAGCTCAGCCT
GCCGCCGGTCGAACGCCGCCTCGAGAAGATCACCGAGGCCGGCAACAACACCTTCCTGCTGAAGAACGACGACGTCTTTC
TCGACATGCTGACCGACTCGGGCGTCAACGCCATGAGCGACCGCCAGCAGGCGGCGATGCTGGTCGCCGACGACAGCTAC
GCCGGCAGCGCCACCTACACCCGGCTCGAGGACAAGCTGCGCGACATCTTCGGCATGCACTACTTCCTGCCGACGCATCA
GGGCCGCGCCTGCGAGCACATCCTCGCCAAGGTGTTCGTCTCGCCCGGCAAGGTGGTGCCGATGAACTATCACTTCACCA
CCACCAAGGCGCATATCACGCTGCAGGGCGGCTCGGTCGAGGAACTGGTGACGGACGCCGGCCTCGAAGTGGTCAGCGTC
AATCCGTTCAAGGGCAACATGGACATCGCCAAGCTGCGCGCGGTGATCGGCCAGCACGGCGCTGGCAACATCGCGTTCGT
GCGGATGGAGAGCGGCACCAATCTGATCGGCGGCCAGCCGTTCTCGCTCGCCAACCTCGCCGAGGTCAGCAACGTCTGCA
AGGAGCACGGCGTGCCGCTGGTGCTCGACGCCAGCCTGCTCGCGGACAATCTGTATTTCAACAAGACCCGCGAGGATCAC
TGCAAGGCGATGTCGATCCGCGAGATCACCCGCCGCACCGCCGACCTGTGCGACATCATCTACTTCTCGGCGCGCAAACT
CGGCTGCGCCCGCGGCGGCGGCATCTGCATCCGCGACCGCGCGCTGTTCGAGAAGATGCGGCCGCTGGTGCCGCTGTACG
AGGGCTTCCTCACTTACGGCGGCATGTCGGTACGTGAAATGGAAGCGCTCACCGTCGGTCTGGAAGAGACCATGGACGAG
GAGATGATCAATCAGGGGCCGATGTTCATCGGCTACATGGTCGAACAATTGCAGGAGCGCGGCGTGCCGGTGATCACGCC
GGCCGGTGGGCTCGGCTGCCACATCGACGCCAAGCGCTTCGTCGACCACATTCCGCAATCGCAATATCCGGCCGGGGCGC
TGGCCTCGGCGCTGTACATCGCCTCGGGCATTCGCGGCATGGAGCGCGGCACGCTGTCGGAACAGCGCGAGCCCGACGGC
AGCGAGATTTTCGCCAATATGGAGCTGGTGCGGCTGGCGCTGCCGCGCCGCGTATTCACGCTGTCGCAGGTCAAATACGC
GGTCGACCGCATCGCCTGGCTGTACGACAATCGCCACCTGATCGGCGGGCTCACCTTCGTCGAGGAGCCGGAGGTGCTGC
GGTTCTTCTACGGCCTGCTCGAGCCGGTGTCGGACTGGCAGAACAAGCTCGTCGCCAAATTCCGCGAGGATTTCGGCGAC
AGCCTGTAA

Upstream 100 bases:

>100_bases
AACGCTGCCGAGCGGCTGGATTGATCTGGCGCAATTGAGATTCCGGCGCTCCTCGATAAGCCCGAAGCCCTCGCGTGGTG
CGGGTTGGGGAGTACGCGGT

Downstream 100 bases:

>100_bases
GCTTCGTCATTGCGAGCACAGCGAAGCAATCCAGCCTCGCGCACGAGCTGGATTGCTTCGTCGCGGAGCCTGTGCCCGGA
CGGCGCGAAGCGCCGATCCG

Product: tryptophanase

Products: NA

Alternate protein names: Beta-tyrosinase [H]

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MATVKFYGNETVPLEMHKVRIVQKLSLPPVERRLEKITEAGNNTFLLKNDDVFLDMLTDSGVNAMSDRQQAAMLVADDSY
AGSATYTRLEDKLRDIFGMHYFLPTHQGRACEHILAKVFVSPGKVVPMNYHFTTTKAHITLQGGSVEELVTDAGLEVVSV
NPFKGNMDIAKLRAVIGQHGAGNIAFVRMESGTNLIGGQPFSLANLAEVSNVCKEHGVPLVLDASLLADNLYFNKTREDH
CKAMSIREITRRTADLCDIIYFSARKLGCARGGGICIRDRALFEKMRPLVPLYEGFLTYGGMSVREMEALTVGLEETMDE
EMINQGPMFIGYMVEQLQERGVPVITPAGGLGCHIDAKRFVDHIPQSQYPAGALASALYIASGIRGMERGTLSEQREPDG
SEIFANMELVRLALPRRVFTLSQVKYAVDRIAWLYDNRHLIGGLTFVEEPEVLRFFYGLLEPVSDWQNKLVAKFREDFGD
SL

Sequences:

>Translated_482_residues
MATVKFYGNETVPLEMHKVRIVQKLSLPPVERRLEKITEAGNNTFLLKNDDVFLDMLTDSGVNAMSDRQQAAMLVADDSY
AGSATYTRLEDKLRDIFGMHYFLPTHQGRACEHILAKVFVSPGKVVPMNYHFTTTKAHITLQGGSVEELVTDAGLEVVSV
NPFKGNMDIAKLRAVIGQHGAGNIAFVRMESGTNLIGGQPFSLANLAEVSNVCKEHGVPLVLDASLLADNLYFNKTREDH
CKAMSIREITRRTADLCDIIYFSARKLGCARGGGICIRDRALFEKMRPLVPLYEGFLTYGGMSVREMEALTVGLEETMDE
EMINQGPMFIGYMVEQLQERGVPVITPAGGLGCHIDAKRFVDHIPQSQYPAGALASALYIASGIRGMERGTLSEQREPDG
SEIFANMELVRLALPRRVFTLSQVKYAVDRIAWLYDNRHLIGGLTFVEEPEVLRFFYGLLEPVSDWQNKLVAKFREDFGD
SL
>Mature_481_residues
ATVKFYGNETVPLEMHKVRIVQKLSLPPVERRLEKITEAGNNTFLLKNDDVFLDMLTDSGVNAMSDRQQAAMLVADDSYA
GSATYTRLEDKLRDIFGMHYFLPTHQGRACEHILAKVFVSPGKVVPMNYHFTTTKAHITLQGGSVEELVTDAGLEVVSVN
PFKGNMDIAKLRAVIGQHGAGNIAFVRMESGTNLIGGQPFSLANLAEVSNVCKEHGVPLVLDASLLADNLYFNKTREDHC
KAMSIREITRRTADLCDIIYFSARKLGCARGGGICIRDRALFEKMRPLVPLYEGFLTYGGMSVREMEALTVGLEETMDEE
MINQGPMFIGYMVEQLQERGVPVITPAGGLGCHIDAKRFVDHIPQSQYPAGALASALYIASGIRGMERGTLSEQREPDGS
EIFANMELVRLALPRRVFTLSQVKYAVDRIAWLYDNRHLIGGLTFVEEPEVLRFFYGLLEPVSDWQNKLVAKFREDFGDS
L

Specific function: Tryptophan catabolism. [C]

COG id: COG3033

COG function: function code E; Tryptophanase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-eliminating lyase family [H]

Homologues:

Organism=Escherichia coli, GI87082323, Length=464, Percent_Identity=35.7758620689655, Blast_Score=287, Evalue=1e-78,

Paralogues:

None

Copy number: 7160 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 460 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011166
- InterPro:   IPR018176
- InterPro:   IPR013441 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.99.2 [H]

Molecular weight: Translated: 53643; Mature: 53511

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVKFYGNETVPLEMHKVRIVQKLSLPPVERRLEKITEAGNNTFLLKNDDVFLDMLTDS
CCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCEEEEEECCC
GVNAMSDRQQAAMLVADDSYAGSATYTRLEDKLRDIFGMHYFLPTHQGRACEHILAKVFV
CCCHHHCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
SPGKVVPMNYHFTTTKAHITLQGGSVEELVTDAGLEVVSVNPFKGNMDIAKLRAVIGQHG
CCCCEEEEEEEEEEEEEEEEEECCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCC
AGNIAFVRMESGTNLIGGQPFSLANLAEVSNVCKEHGVPLVLDASLLADNLYFNKTREDH
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHCCCEECCCCHHH
CKAMSIREITRRTADLCDIIYFSARKLGCARGGGICIRDRALFEKMRPLVPLYEGFLTYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHCCHHHHHHHHHHHC
GMSVREMEALTVGLEETMDEEMINQGPMFIGYMVEQLQERGVPVITPAGGLGCHIDAKRF
CCCHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCCEEECCHHHH
VDHIPQSQYPAGALASALYIASGIRGMERGTLSEQREPDGSEIFANMELVRLALPRRVFT
HHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSQVKYAVDRIAWLYDNRHLIGGLTFVEEPEVLRFFYGLLEPVSDWQNKLVAKFREDFGD
HHHHHHHHHHHHHHCCCCEEEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SL
CC
>Mature Secondary Structure 
ATVKFYGNETVPLEMHKVRIVQKLSLPPVERRLEKITEAGNNTFLLKNDDVFLDMLTDS
CEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCEEEEEECCC
GVNAMSDRQQAAMLVADDSYAGSATYTRLEDKLRDIFGMHYFLPTHQGRACEHILAKVFV
CCCHHHCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
SPGKVVPMNYHFTTTKAHITLQGGSVEELVTDAGLEVVSVNPFKGNMDIAKLRAVIGQHG
CCCCEEEEEEEEEEEEEEEEEECCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCC
AGNIAFVRMESGTNLIGGQPFSLANLAEVSNVCKEHGVPLVLDASLLADNLYFNKTREDH
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHCCCEECCCCHHH
CKAMSIREITRRTADLCDIIYFSARKLGCARGGGICIRDRALFEKMRPLVPLYEGFLTYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHCCHHHHHHHHHHHC
GMSVREMEALTVGLEETMDEEMINQGPMFIGYMVEQLQERGVPVITPAGGLGCHIDAKRF
CCCHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCCEEECCHHHH
VDHIPQSQYPAGALASALYIASGIRGMERGTLSEQREPDGSEIFANMELVRLALPRRVFT
HHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSQVKYAVDRIAWLYDNRHLIGGLTFVEEPEVLRFFYGLLEPVSDWQNKLVAKFREDFGD
HHHHHHHHHHHHHHCCCCEEEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA