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The map label for this gene is pcaR [H]

Identifier: 86748868

GI number: 86748868

Start: 1992576

End: 1993454

Strand: Reverse

Name: pcaR [H]

Synonym: RPB_1745

Alternate gene names: 86748868

Gene position: 1993454-1992576 (Counterclockwise)

Preceding gene: 86748875

Following gene: 86748867

Centisome position: 37.39

GC content: 63.25

Gene sequence:

>879_bases
ATGAAACGTCCGCCGAAAAAAGCCGCGACCGATCGCAGTTTCGTCGTCGCGCTGTCGCGCGGCCTCGAAGTCCTGCGTGC
GTTCGGCCCTAATGACGGCCTGCTCGGCAATCAGGAAATCGCGGCGCGGACCAAACTGCCGAAGCCGACGATCTCGCGGC
TGACCTACACGCTGACCAAGCTCGGCTATCTCACCCAGGTGCCGCGATTCGAGAAGTATCAGCTCGCGCCGGCAGCGATG
TCGCTGGGTTATGCGGCGCTCGCCAATCTCGGCGTCCGTCACCTGTCGCAGCCGTTCCGCGACGAATTGATGCAGCAGAC
CGGCGGCGCGGTCGCGGTCGGCGCGCGCGACCGGATCAGCATGATCTATGTCGGCCAGGCGCGCTCCAGCCTCACCGTGG
GCGTGCAACTCGACGTCGGCTCGCGGATTCCGATCGCGACCACCGCGATGGGCCGCGCTTACTTGTGTGCACTGCAAGGC
GACGAACGTGCGTCCTTGCTGCGCGACATGCGCGAGCACTACGGCAGCCGCTGGCCGCGCATCAAGGAAGGAATCGAACG
CTCCGAAGAGATGGTCGCCAAGCACGGCTTTGCTATTTCGGTCGGCGAATGGCAGGACGACGTGCACGCTGCGGGAGTCG
CGCTGACGTTGAACGATGGCACCGGCCCCTACGCATTCAACTGCGGCGCGCCCGCATTCCGCTTCACGGAAGATCGTCTT
CTCAACGACATTGGACCTCGTCTCGTGGCGATGGTAAGGAAAATCGAAGCGGCGCTCGGTGGGACAGCGGCGCCGCAATC
AAGAAGACCAGACAAATCCGACAACAAGAAAACTAAGTCAGGAGGGAAAGTTGCGCGTGTCGTCGAGGGGATCAGGTAG

Upstream 100 bases:

>100_bases
ATTTCGCAGTGCGAAATTTAGTTTCACATCTTGACAGCGAGGGATATTTTGAAGAGCGTCGCTTGTCAACGACGACCATA
ATCAATCAAACGTGCCGGGA

Downstream 100 bases:

>100_bases
CATCCATCGTCGCGAAGCGTCGCCGATGATCATGCTCAGCAGCCCGGTTCAGGGCAGCAGCAAATGATGCAGGCACATTC
GGGACAAACCGCGTCACCGC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKRPPKKAATDRSFVVALSRGLEVLRAFGPNDGLLGNQEIAARTKLPKPTISRLTYTLTKLGYLTQVPRFEKYQLAPAAM
SLGYAALANLGVRHLSQPFRDELMQQTGGAVAVGARDRISMIYVGQARSSLTVGVQLDVGSRIPIATTAMGRAYLCALQG
DERASLLRDMREHYGSRWPRIKEGIERSEEMVAKHGFAISVGEWQDDVHAAGVALTLNDGTGPYAFNCGAPAFRFTEDRL
LNDIGPRLVAMVRKIEAALGGTAAPQSRRPDKSDNKKTKSGGKVARVVEGIR

Sequences:

>Translated_292_residues
MKRPPKKAATDRSFVVALSRGLEVLRAFGPNDGLLGNQEIAARTKLPKPTISRLTYTLTKLGYLTQVPRFEKYQLAPAAM
SLGYAALANLGVRHLSQPFRDELMQQTGGAVAVGARDRISMIYVGQARSSLTVGVQLDVGSRIPIATTAMGRAYLCALQG
DERASLLRDMREHYGSRWPRIKEGIERSEEMVAKHGFAISVGEWQDDVHAAGVALTLNDGTGPYAFNCGAPAFRFTEDRL
LNDIGPRLVAMVRKIEAALGGTAAPQSRRPDKSDNKKTKSGGKVARVVEGIR
>Mature_292_residues
MKRPPKKAATDRSFVVALSRGLEVLRAFGPNDGLLGNQEIAARTKLPKPTISRLTYTLTKLGYLTQVPRFEKYQLAPAAM
SLGYAALANLGVRHLSQPFRDELMQQTGGAVAVGARDRISMIYVGQARSSLTVGVQLDVGSRIPIATTAMGRAYLCALQG
DERASLLRDMREHYGSRWPRIKEGIERSEEMVAKHGFAISVGEWQDDVHAAGVALTLNDGTGPYAFNCGAPAFRFTEDRL
LNDIGPRLVAMVRKIEAALGGTAAPQSRRPDKSDNKKTKSGGKVARVVEGIR

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=254, Percent_Identity=26.3779527559055, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082359, Length=272, Percent_Identity=22.0588235294118, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786715, Length=254, Percent_Identity=24.4094488188976, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 31720; Mature: 31720

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPPKKAATDRSFVVALSRGLEVLRAFGPNDGLLGNQEIAARTKLPKPTISRLTYTLTK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHH
LGYLTQVPRFEKYQLAPAAMSLGYAALANLGVRHLSQPFRDELMQQTGGAVAVGARDRIS
HHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCEEEECCCCCEE
MIYVGQARSSLTVGVQLDVGSRIPIATTAMGRAYLCALQGDERASLLRDMREHYGSRWPR
EEEEECCCCCEEEEEEECCCCCCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCH
IKEGIERSEEMVAKHGFAISVGEWQDDVHAAGVALTLNDGTGPYAFNCGAPAFRFTEDRL
HHHHHHHHHHHHHHCCCEEEECCCCCCHHHCCEEEEEECCCCCEEEECCCCCHHCHHHHH
LNDIGPRLVAMVRKIEAALGGTAAPQSRRPDKSDNKKTKSGGKVARVVEGIR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MKRPPKKAATDRSFVVALSRGLEVLRAFGPNDGLLGNQEIAARTKLPKPTISRLTYTLTK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHH
LGYLTQVPRFEKYQLAPAAMSLGYAALANLGVRHLSQPFRDELMQQTGGAVAVGARDRIS
HHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCEEEECCCCCEE
MIYVGQARSSLTVGVQLDVGSRIPIATTAMGRAYLCALQGDERASLLRDMREHYGSRWPR
EEEEECCCCCEEEEEEECCCCCCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCH
IKEGIERSEEMVAKHGFAISVGEWQDDVHAAGVALTLNDGTGPYAFNCGAPAFRFTEDRL
HHHHHHHHHHHHHHCCCEEEECCCCCCHHHCCEEEEEECCCCCEEEECCCCCHHCHHHHH
LNDIGPRLVAMVRKIEAALGGTAAPQSRRPDKSDNKKTKSGGKVARVVEGIR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]