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The map label for this gene is ycgM [C]

Identifier: 86748720

GI number: 86748720

Start: 1797960

End: 1798661

Strand: Reverse

Name: ycgM [C]

Synonym: RPB_1595

Alternate gene names: 86748720

Gene position: 1798661-1797960 (Counterclockwise)

Preceding gene: 86748721

Following gene: 86748719

Centisome position: 33.74

GC content: 66.67

Gene sequence:

>702_bases
ATGAGCCAAGCTACTTACGTGATCGCTCCGCTGCCGCAGCCCGCGCTCGCCGTGCAGGGCGACAGCAAGATGTTTCCGGT
GCGCCGGATCTGGTGCGTCGGGCGCAACTATCTCGAGCACATCCGCGAGCTCGGCAATGACGAGCGCAACCCGCCGTTCT
TCTTCGCCAAGCACGCCGACATGATCGCGCCGGACGGCGCCACGATCCCCTACCCGACGCTGACCAAGGACTTCCAGCAC
GAGGTCGAGCTCGTCGTCGCGCTGAAGAGCGGCGGGCTGAACATTTCGGCCGACACCGCGCTCGATCACGTGTTCGGCTA
CGGCGTCGGCGTCGATCTGACGCGGCGGGATCTGCAGACGATCTCGCGCAAGAAGGAGCAGCCCTGGGAGATCGGCAAAT
CGTTCGATGCTTCCGCGCCCTGCGGCGCGCTGCGGCCGGCGGCGGAGATCGGCCATCCGGCCAAGGGCAAGATCTGGCTG
TCGGTCAACGGCGCGGAGCGGCAGAGCGGCGACCTGTCGGACATGATCTGGAACACTGCCGAGATCATCGCCAAACTTTC
GCTGCAGGTCGAACTTTCCGCCGGCGACATCATCATGACAGGTACCCCTGCGGGCGTCGCGGCGCTCGTGCCGGGCGACG
AGGTCGACTGCGGCATCGACGGCATCGGCACGCTCCGCGTGACGATCGGCGAGCCGACCTGA

Upstream 100 bases:

>100_bases
CTGGCCCCCGTCGACGCCGCCATCTAGCACTCCGCCGGCCGGGGCGGCGCGCCGCCGCAACGGCCTCCCGCCCCGCTGTC
CAAGCCTTCGGAAGTCCGTC

Downstream 100 bases:

>100_bases
CTACCCTGTTCTCGCGACCGGCCGATCTGGAATAGCTCGACAATGGTCTGAATCGACCTTTGGTCGGGTGGCGTTTGCGA
CGGGCGGGAGCTAATCGCAG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSQATYVIAPLPQPALAVQGDSKMFPVRRIWCVGRNYLEHIRELGNDERNPPFFFAKHADMIAPDGATIPYPTLTKDFQH
EVELVVALKSGGLNISADTALDHVFGYGVGVDLTRRDLQTISRKKEQPWEIGKSFDASAPCGALRPAAEIGHPAKGKIWL
SVNGAERQSGDLSDMIWNTAEIIAKLSLQVELSAGDIIMTGTPAGVAALVPGDEVDCGIDGIGTLRVTIGEPT

Sequences:

>Translated_233_residues
MSQATYVIAPLPQPALAVQGDSKMFPVRRIWCVGRNYLEHIRELGNDERNPPFFFAKHADMIAPDGATIPYPTLTKDFQH
EVELVVALKSGGLNISADTALDHVFGYGVGVDLTRRDLQTISRKKEQPWEIGKSFDASAPCGALRPAAEIGHPAKGKIWL
SVNGAERQSGDLSDMIWNTAEIIAKLSLQVELSAGDIIMTGTPAGVAALVPGDEVDCGIDGIGTLRVTIGEPT
>Mature_232_residues
SQATYVIAPLPQPALAVQGDSKMFPVRRIWCVGRNYLEHIRELGNDERNPPFFFAKHADMIAPDGATIPYPTLTKDFQHE
VELVVALKSGGLNISADTALDHVFGYGVGVDLTRRDLQTISRKKEQPWEIGKSFDASAPCGALRPAAEIGHPAKGKIWLS
VNGAERQSGDLSDMIWNTAEIIAKLSLQVELSAGDIIMTGTPAGVAALVPGDEVDCGIDGIGTLRVTIGEPT

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=214, Percent_Identity=38.785046728972, Blast_Score=163, Evalue=1e-40,
Organism=Homo sapiens, GI215422413, Length=204, Percent_Identity=40.1960784313725, Blast_Score=160, Evalue=7e-40,
Organism=Homo sapiens, GI66348062, Length=204, Percent_Identity=40.1960784313725, Blast_Score=160, Evalue=7e-40,
Organism=Homo sapiens, GI156231349, Length=205, Percent_Identity=35.1219512195122, Blast_Score=117, Evalue=7e-27,
Organism=Homo sapiens, GI40786394, Length=205, Percent_Identity=34.1463414634146, Blast_Score=114, Evalue=5e-26,
Organism=Escherichia coli, GI1787428, Length=204, Percent_Identity=38.7254901960784, Blast_Score=140, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17557057, Length=191, Percent_Identity=34.5549738219895, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324161, Length=222, Percent_Identity=31.981981981982, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28571789, Length=202, Percent_Identity=30.6930693069307, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI28572127, Length=238, Percent_Identity=32.7731092436975, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24663695, Length=213, Percent_Identity=30.0469483568075, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25031; Mature: 24900

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQATYVIAPLPQPALAVQGDSKMFPVRRIWCVGRNYLEHIRELGNDERNPPFFFAKHAD
CCCCCEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
MIAPDGATIPYPTLTKDFQHEVELVVALKSGGLNISADTALDHVFGYGVGVDLTRRDLQT
EECCCCCCCCCCCCCHHHHCEEEEEEEEECCCCEEEHHHHHHHHHHCCCCCCHHHHHHHH
ISRKKEQPWEIGKSFDASAPCGALRPAAEIGHPAKGKIWLSVNGAERQSGDLSDMIWNTA
HHHCCCCCHHHCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
EIIAKLSLQVELSAGDIIMTGTPAGVAALVPGDEVDCGIDGIGTLRVTIGEPT
HHHEEEEEEEEECCCCEEEECCCCCEEEECCCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
SQATYVIAPLPQPALAVQGDSKMFPVRRIWCVGRNYLEHIRELGNDERNPPFFFAKHAD
CCCCEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
MIAPDGATIPYPTLTKDFQHEVELVVALKSGGLNISADTALDHVFGYGVGVDLTRRDLQT
EECCCCCCCCCCCCCHHHHCEEEEEEEEECCCCEEEHHHHHHHHHHCCCCCCHHHHHHHH
ISRKKEQPWEIGKSFDASAPCGALRPAAEIGHPAKGKIWLSVNGAERQSGDLSDMIWNTA
HHHCCCCCHHHCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
EIIAKLSLQVELSAGDIIMTGTPAGVAALVPGDEVDCGIDGIGTLRVTIGEPT
HHHEEEEEEEEECCCCEEEECCCCCEEEECCCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]