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The map label for this gene is cusB [H]

Identifier: 86748227

GI number: 86748227

Start: 1265108

End: 1266520

Strand: Direct

Name: cusB [H]

Synonym: RPB_1102

Alternate gene names: 86748227

Gene position: 1265108-1266520 (Clockwise)

Preceding gene: 86748226

Following gene: 86748228

Centisome position: 23.73

GC content: 66.17

Gene sequence:

>1413_bases
GTGACGCGCACTGCTCTCGCGAGCCTGGCCGTCGCCGCTTTGGCGGCTGCGGGAGGCGGCCTGTACGGTGTCCGCGAGCA
CCTTCATGCGAGCACCGCGCAGGGCATCGCGTTGTTTGCTCCGGCGCAGGCGCAAAGCAATGACGAGCCGATCTACTATC
AGGATCCGGACGGCAAGCCGTCCTATTCGCTGACACCGCGCAAGACCGCCGACGGGCGCGACTATCGCGCCGTGCCGGCC
GGCGCCGATCTGAATTTCGGCGACGACGCGCCCGTCGCGCCGCCGATGGTGGTTGCGACGGATCGCAAGATCAAATTCTA
TCGCAATCCGATGGGCCTCGCCGACACCTCGCCGGTGCCGAAGAAGGATTCGATGGGGATGGACTACATCCCGGTCTACG
AGGTCGACGGCAGCGACGATGGATCGGTGAAATTGTCGCCAGGGAAGATTCAGCGCACCGGTGTCAAATCGGAAGCCGCC
GGCCGGCGCGTGATCCGCACCACGATCCGCGCGCCGGGCGTGATCCAGCTCGACGAACGCCGAGTCTCGGTGATCGCGAT
GCGCTCGGAAAGCTTCGTGCAGAAGATCGCCGACGTCACCACCGGCAGCCGCGTCACCAAGGACCAGGCCTTGATGGAGG
TCTACAGCTCCGCGATCTCGGCTGCGGCGGCCGACTATATCGCCACCATCAATTCGAAGACCACCGGCGGCGTCGCTGCC
TATGGGCGTGGCTCGCGGCAGCGGCTGATGAATCTCGATGTGCCGGACGCTGCGATTGCCTCGATGGAAAAGGCCGGCAC
GGTGCCGATCGCGCTGGAATGGACGGCGCCGCGCGACGGCGTCGTGCTGGAACGCAACGCCATCGAGGGCATGCGGGCGC
AGCCCGGCGATGTGTTGTTCCGGATCGCCGATACATCCGTGGTGTGGGCGACGCTCGACGTGTCCGAGCGCGATCTCGGC
GCGCTGGCGCCGGGCCAGCCCGTGGTCGTTCGCGCCCGCAGCTATCCAGGGCGCGACTTCACCGGCGAGGTGAAACTGAT
CTATCCGCAGATCGGCAAGGAGACGCGCACGGCGCGCGTCCGGGTCGAACTGGCCAATGCCGATCTGGTTTTGCTACCCG
ACATGTATGTCGATGCCGAGATCGACACCGGCGGCTCTCAGCCGGTGCTGGCGGTGCCGGACAGCTCCATACTGGATTCC
GGCAGCAAGCAGGTGGTGTTCGTCGACCAGGGCGAAGGGCGCTACCAGCCGCGGAGCGTCAAACCCGGCCGTCGCGGAGG
GGATGACGTCGAAATCCGCGAAGGTCTGGCCGAAGGCGAGCGGGTCGTGGTGTCGGCCAACTTCCTGATCGACGCGGAGA
GCAATTTGAATGCCGCGCTGAAGAGCTTCTCGGACGCCGGAGCCAAGCCATGA

Upstream 100 bases:

>100_bases
CGGCGTTCGGCATGGAAGGCCGCTGGCTGTTGTCGCTCGGCGCCAAGGTGCAGGGCGAGACCGGTTCGGTCGAAGGCAAG
CTCGTCATCACGGCGAACAA

Downstream 100 bases:

>100_bases
TCGCCCGTCTGATCGCCTGGTCGGCACGCAATCTGCTGCTGGTGCTGTTCGGCGCCGGCTTCGCCGCCGCGGCCGGAGTC
TATGCGCTGAAACACCTGCC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTRTALASLAVAALAAAGGGLYGVREHLHASTAQGIALFAPAQAQSNDEPIYYQDPDGKPSYSLTPRKTADGRDYRAVPA
GADLNFGDDAPVAPPMVVATDRKIKFYRNPMGLADTSPVPKKDSMGMDYIPVYEVDGSDDGSVKLSPGKIQRTGVKSEAA
GRRVIRTTIRAPGVIQLDERRVSVIAMRSESFVQKIADVTTGSRVTKDQALMEVYSSAISAAAADYIATINSKTTGGVAA
YGRGSRQRLMNLDVPDAAIASMEKAGTVPIALEWTAPRDGVVLERNAIEGMRAQPGDVLFRIADTSVVWATLDVSERDLG
ALAPGQPVVVRARSYPGRDFTGEVKLIYPQIGKETRTARVRVELANADLVLLPDMYVDAEIDTGGSQPVLAVPDSSILDS
GSKQVVFVDQGEGRYQPRSVKPGRRGGDDVEIREGLAEGERVVVSANFLIDAESNLNAALKSFSDAGAKP

Sequences:

>Translated_470_residues
MTRTALASLAVAALAAAGGGLYGVREHLHASTAQGIALFAPAQAQSNDEPIYYQDPDGKPSYSLTPRKTADGRDYRAVPA
GADLNFGDDAPVAPPMVVATDRKIKFYRNPMGLADTSPVPKKDSMGMDYIPVYEVDGSDDGSVKLSPGKIQRTGVKSEAA
GRRVIRTTIRAPGVIQLDERRVSVIAMRSESFVQKIADVTTGSRVTKDQALMEVYSSAISAAAADYIATINSKTTGGVAA
YGRGSRQRLMNLDVPDAAIASMEKAGTVPIALEWTAPRDGVVLERNAIEGMRAQPGDVLFRIADTSVVWATLDVSERDLG
ALAPGQPVVVRARSYPGRDFTGEVKLIYPQIGKETRTARVRVELANADLVLLPDMYVDAEIDTGGSQPVLAVPDSSILDS
GSKQVVFVDQGEGRYQPRSVKPGRRGGDDVEIREGLAEGERVVVSANFLIDAESNLNAALKSFSDAGAKP
>Mature_469_residues
TRTALASLAVAALAAAGGGLYGVREHLHASTAQGIALFAPAQAQSNDEPIYYQDPDGKPSYSLTPRKTADGRDYRAVPAG
ADLNFGDDAPVAPPMVVATDRKIKFYRNPMGLADTSPVPKKDSMGMDYIPVYEVDGSDDGSVKLSPGKIQRTGVKSEAAG
RRVIRTTIRAPGVIQLDERRVSVIAMRSESFVQKIADVTTGSRVTKDQALMEVYSSAISAAAADYIATINSKTTGGVAAY
GRGSRQRLMNLDVPDAAIASMEKAGTVPIALEWTAPRDGVVLERNAIEGMRAQPGDVLFRIADTSVVWATLDVSERDLGA
LAPGQPVVVRARSYPGRDFTGEVKLIYPQIGKETRTARVRVELANADLVLLPDMYVDAEIDTGGSQPVLAVPDSSILDSG
SKQVVFVDQGEGRYQPRSVKPGRRGGDDVEIREGLAEGERVVVSANFLIDAESNLNAALKSFSDAGAKP

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=362, Percent_Identity=28.1767955801105, Blast_Score=146, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49950; Mature: 49819

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTALASLAVAALAAAGGGLYGVREHLHASTAQGIALFAPAQAQSNDEPIYYQDPDGKP
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCC
SYSLTPRKTADGRDYRAVPAGADLNFGDDAPVAPPMVVATDRKIKFYRNPMGLADTSPVP
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCCCCCCCC
KKDSMGMDYIPVYEVDGSDDGSVKLSPGKIQRTGVKSEAAGRRVIRTTIRAPGVIQLDER
CCCCCCCCEEEEEEECCCCCCEEEECCCCEEECCCCCHHHCCCEEHHHHCCCCEEEECCC
RVSVIAMRSESFVQKIADVTTGSRVTKDQALMEVYSSAISAAAADYIATINSKTTGGVAA
EEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEE
YGRGSRQRLMNLDVPDAAIASMEKAGTVPIALEWTAPRDGVVLERNAIEGMRAQPGDVLF
CCCCCHHHEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCEEE
RIADTSVVWATLDVSERDLGALAPGQPVVVRARSYPGRDFTGEVKLIYPQIGKETRTARV
EEECCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCEEEEE
RVELANADLVLLPDMYVDAEIDTGGSQPVLAVPDSSILDSGSKQVVFVDQGEGRYQPRSV
EEEEECCCEEEECCEEEEEEECCCCCCCEEECCCCHHHCCCCCEEEEEECCCCCCCCCCC
KPGRRGGDDVEIREGLAEGERVVVSANFLIDAESNLNAALKSFSDAGAKP
CCCCCCCCCHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TRTALASLAVAALAAAGGGLYGVREHLHASTAQGIALFAPAQAQSNDEPIYYQDPDGKP
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCC
SYSLTPRKTADGRDYRAVPAGADLNFGDDAPVAPPMVVATDRKIKFYRNPMGLADTSPVP
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCCCCCCCC
KKDSMGMDYIPVYEVDGSDDGSVKLSPGKIQRTGVKSEAAGRRVIRTTIRAPGVIQLDER
CCCCCCCCEEEEEEECCCCCCEEEECCCCEEECCCCCHHHCCCEEHHHHCCCCEEEECCC
RVSVIAMRSESFVQKIADVTTGSRVTKDQALMEVYSSAISAAAADYIATINSKTTGGVAA
EEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEE
YGRGSRQRLMNLDVPDAAIASMEKAGTVPIALEWTAPRDGVVLERNAIEGMRAQPGDVLF
CCCCCHHHEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCEEE
RIADTSVVWATLDVSERDLGALAPGQPVVVRARSYPGRDFTGEVKLIYPQIGKETRTARV
EEECCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCEEEEE
RVELANADLVLLPDMYVDAEIDTGGSQPVLAVPDSSILDSGSKQVVFVDQGEGRYQPRSV
EEEEECCCEEEECCEEEEEEECCCCCCCEEECCCCHHHCCCCCEEEEEECCCCCCCCCCC
KPGRRGGDDVEIREGLAEGERVVVSANFLIDAESNLNAALKSFSDAGAKP
CCCCCCCCCHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]