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The map label for this gene is modD [H]

Identifier: 86748181

GI number: 86748181

Start: 1211057

End: 1211905

Strand: Direct

Name: modD [H]

Synonym: RPB_1056

Alternate gene names: 86748181

Gene position: 1211057-1211905 (Clockwise)

Preceding gene: 86748178

Following gene: 86748183

Centisome position: 22.71

GC content: 72.79

Gene sequence:

>849_bases
ATGCCCGCGGCCGCCACCACCGAACTGGAGCGCCTGCTCGACGACGACGTGCCGCATGGCGACCTCACCACCGAGTTGCT
CGGCATCGGCGGTGAGGCCGGGGTGATGGCGTTCACCGCCCGCGATCCGATGGTGCTGGCGCTGGCCGAGGATGCCGCGG
CGATCCTGCGTCTGTGCGGCTGCGAGGTCGAACTGCTGGCGGCCACGGGCACCAAGCTCGCGCCCGGCGCGCCGATCCTG
ATCGCGCGCGGCGCGGCGTCCGGCCTGCTGCGCGGCTGGAAGGTGGCGCAGACGCTGATCGAGATCTGGTCGGGGGTCGC
GACTGCCACCCGCGAGATCGTCGAGGCCGCGCGCGCGGTGTCGCCCGGCATCGCGATTGCCTGCACCCGCAAGAACACGC
CCGGCACCAAGCGCTTCGCGGTCGCCGCGGTGAAGGCCGGCGGCGCCGGCATGCACCGGCTCGGGCTGTCGGAAACCATT
CTGGTGTTCGCCGAGCATCGCGGCTTTCTCGACGAGCCCGCGGCGGCGACGGTGGCGCGGCTGCGCGCTGCCGCGCCGGA
GAAGAAACTGGTCACCGAAGTGTCCACGATCGACGCGGCGCTGGCCGCGGCCGCGGCCGGCTACGACGTGTTGCAGCTCG
AGAAATTCGCGCCCGCCGACGTCGCGACGCTGGTCGCGCGTCTCGCCGAGACGCCGCTGCGCCCGGTGATCGCCGCCGCC
GGCGGCGTCAACGCAAGCAACGCCGCCGCCTATGCTGCGGCCGGCGCGCAGGTGCTGGTGACGTCGGCGCCGTACATGGC
CAAGCCGAGGGACGTGCAGGTGCGGATCAGGCGGGCAACTACAAAGTAA

Upstream 100 bases:

>100_bases
ACCGCCGTCACGAATCCGACAGCGTTGTATAATCATAGACACAACGGTTGCGACCGGGAATGGTCCTGCCCCCGCCATTG
CCCACCTGAAGGATGACCCG

Downstream 100 bases:

>100_bases
CGAGTTGAGTGACAAAGCCACCCCAGGCACAGCGAGCCCCCTCTCCCGCCTGCGGGAGAGGGCTGGGGTGAGGGCGCGCC
GAGCACAGCGCGCTCCCTCT

Product: modD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MPAAATTELERLLDDDVPHGDLTTELLGIGGEAGVMAFTARDPMVLALAEDAAAILRLCGCEVELLAATGTKLAPGAPIL
IARGAASGLLRGWKVAQTLIEIWSGVATATREIVEAARAVSPGIAIACTRKNTPGTKRFAVAAVKAGGAGMHRLGLSETI
LVFAEHRGFLDEPAAATVARLRAAAPEKKLVTEVSTIDAALAAAAAGYDVLQLEKFAPADVATLVARLAETPLRPVIAAA
GGVNASNAAAYAAAGAQVLVTSAPYMAKPRDVQVRIRRATTK

Sequences:

>Translated_282_residues
MPAAATTELERLLDDDVPHGDLTTELLGIGGEAGVMAFTARDPMVLALAEDAAAILRLCGCEVELLAATGTKLAPGAPIL
IARGAASGLLRGWKVAQTLIEIWSGVATATREIVEAARAVSPGIAIACTRKNTPGTKRFAVAAVKAGGAGMHRLGLSETI
LVFAEHRGFLDEPAAATVARLRAAAPEKKLVTEVSTIDAALAAAAAGYDVLQLEKFAPADVATLVARLAETPLRPVIAAA
GGVNASNAAAYAAAGAQVLVTSAPYMAKPRDVQVRIRRATTK
>Mature_281_residues
PAAATTELERLLDDDVPHGDLTTELLGIGGEAGVMAFTARDPMVLALAEDAAAILRLCGCEVELLAATGTKLAPGAPILI
ARGAASGLLRGWKVAQTLIEIWSGVATATREIVEAARAVSPGIAIACTRKNTPGTKRFAVAAVKAGGAGMHRLGLSETIL
VFAEHRGFLDEPAAATVARLRAAAPEKKLVTEVSTIDAALAAAAAGYDVLQLEKFAPADVATLVARLAETPLRPVIAAAG
GVNASNAAAYAAAGAQVLVTSAPYMAKPRDVQVRIRRATTK

Specific function: NAD biosynthesis; aspartate to NaMN; third (last) step. [C]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family [H]

Homologues:

Organism=Homo sapiens, GI45269149, Length=223, Percent_Identity=30.9417040358744, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321162, Length=273, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006242
- InterPro:   IPR002638
- InterPro:   IPR022412 [H]

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N [H]

EC number: 2.4.2.-

Molecular weight: Translated: 28830; Mature: 28698

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAATTELERLLDDDVPHGDLTTELLGIGGEAGVMAFTARDPMVLALAEDAAAILRLCG
CCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHC
CEVELLAATGTKLAPGAPILIARGAASGLLRGWKVAQTLIEIWSGVATATREIVEAARAV
CCEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SPGIAIACTRKNTPGTKRFAVAAVKAGGAGMHRLGLSETILVFAEHRGFLDEPAAATVAR
CCCEEEEEECCCCCCCCCEEEEEEECCCCCHHHCCCCCEEEEEEECCCCCCCHHHHHHHH
LRAAAPEKKLVTEVSTIDAALAAAAAGYDVLQLEKFAPADVATLVARLAETPLRPVIAAA
HHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHC
GGVNASNAAAYAAAGAQVLVTSAPYMAKPRDVQVRIRRATTK
CCCCCCCCHHHHHCCCEEEEECCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
PAAATTELERLLDDDVPHGDLTTELLGIGGEAGVMAFTARDPMVLALAEDAAAILRLCG
CCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHC
CEVELLAATGTKLAPGAPILIARGAASGLLRGWKVAQTLIEIWSGVATATREIVEAARAV
CCEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SPGIAIACTRKNTPGTKRFAVAAVKAGGAGMHRLGLSETILVFAEHRGFLDEPAAATVAR
CCCEEEEEECCCCCCCCCEEEEEEECCCCCHHHCCCCCEEEEEEECCCCCCCHHHHHHHH
LRAAAPEKKLVTEVSTIDAALAAAAAGYDVLQLEKFAPADVATLVARLAETPLRPVIAAA
HHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHC
GGVNASNAAAYAAAGAQVLVTSAPYMAKPRDVQVRIRRATTK
CCCCCCCCHHHHHCCCEEEEECCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8491722 [H]