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The map label for this gene is cutL [H]

Identifier: 86748038

GI number: 86748038

Start: 1050325

End: 1052667

Strand: Reverse

Name: cutL [H]

Synonym: RPB_0912

Alternate gene names: 86748038

Gene position: 1052667-1050325 (Counterclockwise)

Preceding gene: 86748039

Following gene: 86748037

Centisome position: 19.74

GC content: 66.79

Gene sequence:

>2343_bases
ATGGGCATCGAGGGCATCGGCGCGAGCGTCGTGCGCAAGGAAGACCGTCGCTTCATCACCGGCAAGGGCCGCTATGTCGA
CGACATCAAGATCATCGGCATGACGCATGCGTATTTCCTGCGCAGCCCGCATGCCCACGCCAGGATCAAGCGCATCGACG
TCGAGGCCGCCAAGGCGATGCCTGGGGTGGTCGACGTGCTGACCGGGCAGCAGATCGTCGACGACAAGGTCGGCAATCTG
ATCTGCGGCTGGGCGATCCACTCCAAGGACGGCTCGGCGATGAAGATGGGCGCGTGGCCGGCGATGGCGCCGGAGACGGT
GCGCTTCGTCGGCCAGGCGGTCGCGGTGGTGATCGCCGAGACCCGAAACCTCGCCCGCGACGCCGCCGAGGCGATCGTGG
TGGAGTACGAAGAGCTGCCTGCCGTCGCCGATGTCAAGGCCGCGATCGCGCCCGGCGCGCCGCAGCTTCATCCCGAGGCC
CCCGGCAACATCGTCTATGACTGGGAGATCGGCGACCAGAAGGCGGTCGACGAGGCCTTCGGCAAGGCCGCCAATGTGGT
GTCGTTCGAACTGACCAACAACCGGCTGGTGCCGAACGCGATGGAGCCGCGCGCCGCACTCGCCGACTACAACGAGGCGG
AAGAGCACTTCACGCTGTACACCACGTCGCAAAATCCGCACGTCGCCCGGCTGGTGCTGTCGGCGTTCTACAACATCGCG
CCCGAGCACAAGCTGCGGGTGGTGGCGCCCGACGTCGGCGGCGGCTTCGGCTCCAAGATCTTCATCTATCCGGAAGAGAT
GGTGGCGCTGTGGGCCTCCAAGAAGGTCGGCCGCCCGGTGAAATGGACCGGCGACCGCAACGAGGCGTTCCTGACCGACG
CCCACGGCCGCGACCACGTCTCCAAGGCCGAGATGGCGTTCGACAAGGACAACAAGATGCTGGCGCTGCGGGTGACGACC
CACGCCAATTTCGGCGCCTACATGTCGCTGTTCTCGTCCTCGGTACCGACTTATCTCTACGCCACGCTGCTGTCGGGCCA
GTACAACATCCCGGCGATCTACACCGAGGTGATCGGCGTCTACACCAACACCACGCCGGTCGACGCCTATCGCGGCGCCG
GGCGGCCCGAGGCGTGCTACCTGCTGGAGCGGCTGGTCGAGACCGCGGCGCGGCAGCTCAAGGTCGACCCGGCCGAGCTG
CGGCGCAAGAACTTCATCACCCAGTTCCCGCATCAGACCCCGGTGATCATGGCCTACGACATCGGCGACTTCAACGCGTC
GCTCGACGCCGCGCTGAAGGCCGCCGACTATGCCGGCTTCCCGGCGCGCAAGGCCAAGGCCAAGGCCGAGGGCAAGCTGC
GCGGGCTCGGCTTCTCCTGCTACATCGAGGCCTGCGGCATCGCGCCCTCGAAAGCGGTGGGCTCGCTCGGCGCCGGCGTC
GGTCTGTGGGAATCCGCGGAGGTGCGCGTCAACCCGGTCGGCACCATCGAGATCCTGACCGGTTCGCACAGCCACGGCCA
GGGCCACGAGACCACCTTCGCCCAATTGGTCGCCGATCGCCTCGGCATTCCGATCAACCAGGTGTCGATCGTGCACGGCG
ACACCGACAAGGTGCAGTTCGGCATGGGCACCTACGGCTCGCGCTCCGCCGCGGTCGGCATGTCGGCGATCTTCAAGGCG
ATGGAGAAGGTCGAGGCCAAGGCCAAGAAGATCGCGGCGCATCAGCTCGAGGCCAGCGAGGGCGACATCGTCATCGAGAA
CGGCGAGTTCAAGGTCACCGGCACCGACAAGTCGATCGCGCTGCCGATGGTGGCGCTGGCCGCCTACACGGCGCACAATC
TGCCCGACGGCATGGAGCCCGGCCTGAAGGAGAGCGCGTTCTACGATCCGACCAACTTCACGTTCCCGGCCGGCTCCTAC
ATCTGCGAGCTCGAAGTCGATCCCGGCACCGGCAAGACCTCGTTCGTCAATTTCGTCGCGGTCGATGATTTCGGCCGGCT
GATCAATCCGATGATCGTCGAAGGCCAGGTCCATGGCGGCCTCGTCCAGGGCATCGGCCAGGCGCTGCTGGAGCAGGCGA
TCTACGACGACACCGGCCAGCTCGTCACCGCGTCGTTCATGGACTACGCGATGCCGCGCGCCGACGACGTGCCGTCGTTC
AAGGTGTCGCACACCGAGACGCTGTGTCCGGGCAATCCGCTCGGCGTCAAGGGCTGCGGCGAGGCCGGCGCGATCGGCGC
CTCGGCGGCGGTGATCAACGCCATCACCGACGCGATCGGCAACAACAAGCTCGAAATGCCGGCGACGCCCGACCGGGTGT
GGCACGCGATCCAAGCGGCCTGA

Upstream 100 bases:

>100_bases
GCGCTGCCGCCTCCGCCGTTTTCGTCACGTATCAACTCAATCGAGCTGCGCCCGCGTCGTCGACGTCGCGGCCGACGCAG
TCGGACAGGGAGCAAACACA

Downstream 100 bases:

>100_bases
GGGAGGACACAGCATGTATTCCACCAACTATCACCGCCCCTCGTCGGTCGAGGAAGCCGTCGCGCTGTTCGGCAAGGGCA
GCGATCCGAAATATCTCGCC

Product: carbon-monoxide dehydrogenase large subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 780; Mature: 779

Protein sequence:

>780_residues
MGIEGIGASVVRKEDRRFITGKGRYVDDIKIIGMTHAYFLRSPHAHARIKRIDVEAAKAMPGVVDVLTGQQIVDDKVGNL
ICGWAIHSKDGSAMKMGAWPAMAPETVRFVGQAVAVVIAETRNLARDAAEAIVVEYEELPAVADVKAAIAPGAPQLHPEA
PGNIVYDWEIGDQKAVDEAFGKAANVVSFELTNNRLVPNAMEPRAALADYNEAEEHFTLYTTSQNPHVARLVLSAFYNIA
PEHKLRVVAPDVGGGFGSKIFIYPEEMVALWASKKVGRPVKWTGDRNEAFLTDAHGRDHVSKAEMAFDKDNKMLALRVTT
HANFGAYMSLFSSSVPTYLYATLLSGQYNIPAIYTEVIGVYTNTTPVDAYRGAGRPEACYLLERLVETAARQLKVDPAEL
RRKNFITQFPHQTPVIMAYDIGDFNASLDAALKAADYAGFPARKAKAKAEGKLRGLGFSCYIEACGIAPSKAVGSLGAGV
GLWESAEVRVNPVGTIEILTGSHSHGQGHETTFAQLVADRLGIPINQVSIVHGDTDKVQFGMGTYGSRSAAVGMSAIFKA
MEKVEAKAKKIAAHQLEASEGDIVIENGEFKVTGTDKSIALPMVALAAYTAHNLPDGMEPGLKESAFYDPTNFTFPAGSY
ICELEVDPGTGKTSFVNFVAVDDFGRLINPMIVEGQVHGGLVQGIGQALLEQAIYDDTGQLVTASFMDYAMPRADDVPSF
KVSHTETLCPGNPLGVKGCGEAGAIGASAAVINAITDAIGNNKLEMPATPDRVWHAIQAA

Sequences:

>Translated_780_residues
MGIEGIGASVVRKEDRRFITGKGRYVDDIKIIGMTHAYFLRSPHAHARIKRIDVEAAKAMPGVVDVLTGQQIVDDKVGNL
ICGWAIHSKDGSAMKMGAWPAMAPETVRFVGQAVAVVIAETRNLARDAAEAIVVEYEELPAVADVKAAIAPGAPQLHPEA
PGNIVYDWEIGDQKAVDEAFGKAANVVSFELTNNRLVPNAMEPRAALADYNEAEEHFTLYTTSQNPHVARLVLSAFYNIA
PEHKLRVVAPDVGGGFGSKIFIYPEEMVALWASKKVGRPVKWTGDRNEAFLTDAHGRDHVSKAEMAFDKDNKMLALRVTT
HANFGAYMSLFSSSVPTYLYATLLSGQYNIPAIYTEVIGVYTNTTPVDAYRGAGRPEACYLLERLVETAARQLKVDPAEL
RRKNFITQFPHQTPVIMAYDIGDFNASLDAALKAADYAGFPARKAKAKAEGKLRGLGFSCYIEACGIAPSKAVGSLGAGV
GLWESAEVRVNPVGTIEILTGSHSHGQGHETTFAQLVADRLGIPINQVSIVHGDTDKVQFGMGTYGSRSAAVGMSAIFKA
MEKVEAKAKKIAAHQLEASEGDIVIENGEFKVTGTDKSIALPMVALAAYTAHNLPDGMEPGLKESAFYDPTNFTFPAGSY
ICELEVDPGTGKTSFVNFVAVDDFGRLINPMIVEGQVHGGLVQGIGQALLEQAIYDDTGQLVTASFMDYAMPRADDVPSF
KVSHTETLCPGNPLGVKGCGEAGAIGASAAVINAITDAIGNNKLEMPATPDRVWHAIQAA
>Mature_779_residues
GIEGIGASVVRKEDRRFITGKGRYVDDIKIIGMTHAYFLRSPHAHARIKRIDVEAAKAMPGVVDVLTGQQIVDDKVGNLI
CGWAIHSKDGSAMKMGAWPAMAPETVRFVGQAVAVVIAETRNLARDAAEAIVVEYEELPAVADVKAAIAPGAPQLHPEAP
GNIVYDWEIGDQKAVDEAFGKAANVVSFELTNNRLVPNAMEPRAALADYNEAEEHFTLYTTSQNPHVARLVLSAFYNIAP
EHKLRVVAPDVGGGFGSKIFIYPEEMVALWASKKVGRPVKWTGDRNEAFLTDAHGRDHVSKAEMAFDKDNKMLALRVTTH
ANFGAYMSLFSSSVPTYLYATLLSGQYNIPAIYTEVIGVYTNTTPVDAYRGAGRPEACYLLERLVETAARQLKVDPAELR
RKNFITQFPHQTPVIMAYDIGDFNASLDAALKAADYAGFPARKAKAKAEGKLRGLGFSCYIEACGIAPSKAVGSLGAGVG
LWESAEVRVNPVGTIEILTGSHSHGQGHETTFAQLVADRLGIPINQVSIVHGDTDKVQFGMGTYGSRSAAVGMSAIFKAM
EKVEAKAKKIAAHQLEASEGDIVIENGEFKVTGTDKSIALPMVALAAYTAHNLPDGMEPGLKESAFYDPTNFTFPAGSYI
CELEVDPGTGKTSFVNFVAVDDFGRLINPMIVEGQVHGGLVQGIGQALLEQAIYDDTGQLVTASFMDYAMPRADDVPSFK
VSHTETLCPGNPLGVKGCGEAGAIGASAAVINAITDAIGNNKLEMPATPDRVWHAIQAA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=790, Percent_Identity=24.6835443037975, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI91823271, Length=791, Percent_Identity=25.6637168141593, Blast_Score=160, Evalue=5e-39,
Organism=Escherichia coli, GI1789230, Length=791, Percent_Identity=28.4450063211125, Blast_Score=262, Evalue=5e-71,
Organism=Escherichia coli, GI1789246, Length=827, Percent_Identity=25.7557436517533, Blast_Score=205, Evalue=1e-53,
Organism=Escherichia coli, GI1786478, Length=747, Percent_Identity=25.3012048192771, Blast_Score=133, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17540638, Length=799, Percent_Identity=24.0300375469337, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17539860, Length=753, Percent_Identity=25.7636122177955, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI32566215, Length=616, Percent_Identity=25.3246753246753, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI17737937, Length=785, Percent_Identity=27.0063694267516, Blast_Score=147, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 83570; Mature: 83439

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS00969 ANTENNA_COMP_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIEGIGASVVRKEDRRFITGKGRYVDDIKIIGMTHAYFLRSPHAHARIKRIDVEAAKAM
CCCCCCCHHHHHHCCCEEEECCCCEECCEEEEEEEHHHHHCCCCCHHEEEEEEHHHHHCC
PGVVDVLTGQQIVDDKVGNLICGWAIHSKDGSAMKMGAWPAMAPETVRFVGQAVAVVIAE
CCHHHHHCCCHHHHHHHCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
TRNLARDAAEAIVVEYEELPAVADVKAAIAPGAPQLHPEAPGNIVYDWEIGDQKAVDEAF
HHHHHHHHHHHEEEEHHHCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
GKAANVVSFELTNNRLVPNAMEPRAALADYNEAEEHFTLYTTSQNPHVARLVLSAFYNIA
CCCCCEEEEEECCCEECCCCCCCHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCC
PEHKLRVVAPDVGGGFGSKIFIYPEEMVALWASKKVGRPVKWTGDRNEAFLTDAHGRDHV
CCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCCCEEECCCCCCEEEECCCCCCCC
SKAEMAFDKDNKMLALRVTTHANFGAYMSLFSSSVPTYLYATLLSGQYNIPAIYTEVIGV
HHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHEEHHHH
YTNTTPVDAYRGAGRPEACYLLERLVETAARQLKVDPAELRRKNFITQFPHQTPVIMAYD
CCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEE
IGDFNASLDAALKAADYAGFPARKAKAKAEGKLRGLGFSCYIEACGIAPSKAVGSLGAGV
CCCCCCCHHHHHHHHCCCCCCCHHHHHCCCCCEECCCEEEEEEECCCCCHHHHHHCCCCC
GLWESAEVRVNPVGTIEILTGSHSHGQGHETTFAQLVADRLGIPINQVSIVHGDTDKVQF
CCCCCCCEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEE
GMGTYGSRSAAVGMSAIFKAMEKVEAKAKKIAAHQLEASEGDIVIENGEFKVTGTDKSIA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEECCCCCHH
LPMVALAAYTAHNLPDGMEPGLKESAFYDPTNFTFPAGSYICELEVDPGTGKTSFVNFVA
HHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCCCEEEEEEE
VDDFGRLINPMIVEGQVHGGLVQGIGQALLEQAIYDDTGQLVTASFMDYAMPRADDVPSF
ECCHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCCE
KVSHTETLCPGNPLGVKGCGEAGAIGASAAVINAITDAIGNNKLEMPATPDRVWHAIQAA
EECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
GIEGIGASVVRKEDRRFITGKGRYVDDIKIIGMTHAYFLRSPHAHARIKRIDVEAAKAM
CCCCCCHHHHHHCCCEEEECCCCEECCEEEEEEEHHHHHCCCCCHHEEEEEEHHHHHCC
PGVVDVLTGQQIVDDKVGNLICGWAIHSKDGSAMKMGAWPAMAPETVRFVGQAVAVVIAE
CCHHHHHCCCHHHHHHHCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
TRNLARDAAEAIVVEYEELPAVADVKAAIAPGAPQLHPEAPGNIVYDWEIGDQKAVDEAF
HHHHHHHHHHHEEEEHHHCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
GKAANVVSFELTNNRLVPNAMEPRAALADYNEAEEHFTLYTTSQNPHVARLVLSAFYNIA
CCCCCEEEEEECCCEECCCCCCCHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCC
PEHKLRVVAPDVGGGFGSKIFIYPEEMVALWASKKVGRPVKWTGDRNEAFLTDAHGRDHV
CCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCCCEEECCCCCCEEEECCCCCCCC
SKAEMAFDKDNKMLALRVTTHANFGAYMSLFSSSVPTYLYATLLSGQYNIPAIYTEVIGV
HHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHEEHHHH
YTNTTPVDAYRGAGRPEACYLLERLVETAARQLKVDPAELRRKNFITQFPHQTPVIMAYD
CCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEE
IGDFNASLDAALKAADYAGFPARKAKAKAEGKLRGLGFSCYIEACGIAPSKAVGSLGAGV
CCCCCCCHHHHHHHHCCCCCCCHHHHHCCCCCEECCCEEEEEEECCCCCHHHHHHCCCCC
GLWESAEVRVNPVGTIEILTGSHSHGQGHETTFAQLVADRLGIPINQVSIVHGDTDKVQF
CCCCCCCEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEE
GMGTYGSRSAAVGMSAIFKAMEKVEAKAKKIAAHQLEASEGDIVIENGEFKVTGTDKSIA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEECCCCCHH
LPMVALAAYTAHNLPDGMEPGLKESAFYDPTNFTFPAGSYICELEVDPGTGKTSFVNFVA
HHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCCCEEEEEEE
VDDFGRLINPMIVEGQVHGGLVQGIGQALLEQAIYDDTGQLVTASFMDYAMPRADDVPSF
ECCHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCCE
KVSHTETLCPGNPLGVKGCGEAGAIGASAAVINAITDAIGNNKLEMPATPDRVWHAIQAA
EECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]