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The map label for this gene is mhpA [H]

Identifier: 86748029

GI number: 86748029

Start: 1040763

End: 1042385

Strand: Direct

Name: mhpA [H]

Synonym: RPB_0903

Alternate gene names: 86748029

Gene position: 1040763-1042385 (Clockwise)

Preceding gene: 86748027

Following gene: 86748030

Centisome position: 19.52

GC content: 68.64

Gene sequence:

>1623_bases
ATGCCCGCCCGCGAGAGTTTCCAGTTCGGTTATCGCCGCCACCCCGATCAGGACCGCGCAGCCCCGGATGGTGGGCGCGA
GCCGGCGCGCCATCCCGTGGTGATCGTCGGCGCCGGCCCTGTCGGGCTGTCGCTGGCGATCGATCTGGCGCAGCGCGGCC
AGCGCGTCGTACTGCTCGACGACGCCGACCGGATCGGCGAGGGCTCGCGCGCGATCTGTTTCTCCAAGCGCGCGCTGGAA
GTGTGGGACCGGCTCGGCGTCGGCAGCCGCATGGTCGAGAAGGGCGTGGTCTGGCAGGTCGGCAAGATCTTCCGCCGCGA
CGAGATGGTGTATCGCTTCGACCTGCTGCCCGAGACCGGCCACAAGATGCCGGCCTTCATCAATCTGCAGCAATATTACG
CCGAAGCCTTCCTGGTCGACCGCGTGCAGGAACTGCCGCAGATCGATCTGCGCTGGCGCAACAAGGTGATCGCGCTGGCG
CAGCACAACGACCACGCGGTGCTGACGATCGAGACGCCGGACGGGCCGTATCGGTTGGCGGCGGACTACGTGGTGGCCTG
CGACGGCGCGCGCTCGGCGTTGCGCGGCCTGGTCGGCGCGGAGTTCGAAGGTGAAGTGTTCGAGGATCAGTTCCTGATCG
CCGACGTCAAGATGACGGCGGAATTCCCCACCGAGCGCTGGTTCTGGTTCGATCCGCCGTTCCATGCCGGGCAGTCGGCG
CTGCTGCATCGCCAGCCCGACGATGTGTGGCGCATCGATCTGCAGATCGGCGCCGAGGCCGACGCGGCGGTCGAGCGATT
GCCCGAGAATGTCCGGCCGCGGATCGAGCGGATGCTCGGCCACGGCGATTTCTCCTTCGAGTGGATCTCGGTCTACAAGT
TCCAGTGCCGGCGGATGCAGCGCTTCCTGCACGAGCGGGTGATCTTCGCCGGCGATTCCGCGCATCAGGTCTCGCCCTTC
GGTGCGCGCGGCGCCAATTCCGGGCTCGAGGATGGCGAGAACCTTGCCTGGAAACTCGCGCTGGTGCTGCGCGGCGAGGC
GCCCGCGAGCCTGCTCGACTCTTATGAAATCGAACGCGGCCAGGCCGCCGACGACAACATCCGCCATTCGACCCGCTCGA
CCGATTTCATCGCGCCGCATTCGCAGCAGGAGCGCCGGCTGCGCGATGCCGCGCTGGCGCTCGCCAAGGAGGTCGACTTC
GCCAAGCGCATGGTCAATGCCGGCCGGCTGTCGACGCCGACCGTCTACGACAGTCCGCTGTCGACGCCCGATGCCGATGC
CTGGGGCGCGGGGCCGAAGCCCGGCGCGGCGATGCTCGATGCGCCGCTGGCGGCGGATGGCGCGCCGATGTTCCTCACCG
AGGCGTTCAAATCCGCCGGCTGCGACTTCGTGCTGCTCGAGAGCGCCAATGGTGTTGCCGCGCCGGTGCCGCAAGGTGTG
CGCAGCCTGCGCATCGGCAAGGACTCGCCGCTGCAGGACGCCGAAGGCGTGTTCGCCAAACGCTACGACGCCACCCCGGG
CTCGGCCTATCTGCTCCGCCCCGACGGCTACGTCGCCGCGCGGTTCCGGCATCCGACGACAGCTACAATCCATGCGGCGC
TGGCGCGGGCAAGCGGGCGATGA

Upstream 100 bases:

>100_bases
GGGGCGAGGCCGGCTTAGATGGTTGCAAATGAAACTATCATGCAGGAGGAAGCCTTGACCAGCGTTTTGCCGTCCCGCAT
GGGCCGAGCGGGCTGAGGCC

Downstream 100 bases:

>100_bases
GGGCGCGGCGATGATGTCTGTCGAGACTCAGAGCTTCGAACGAGCATCGCAGCGCTTGGGGCGGAGCCTCTCACCGCAGG
CACAACCGAACCTCTCCCCG

Product: FAD-dependent oxidoreductase

Products: NA

Alternate protein names: 3-HCI hydroxylase; 3-HPP hydroxylase [H]

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MPARESFQFGYRRHPDQDRAAPDGGREPARHPVVIVGAGPVGLSLAIDLAQRGQRVVLLDDADRIGEGSRAICFSKRALE
VWDRLGVGSRMVEKGVVWQVGKIFRRDEMVYRFDLLPETGHKMPAFINLQQYYAEAFLVDRVQELPQIDLRWRNKVIALA
QHNDHAVLTIETPDGPYRLAADYVVACDGARSALRGLVGAEFEGEVFEDQFLIADVKMTAEFPTERWFWFDPPFHAGQSA
LLHRQPDDVWRIDLQIGAEADAAVERLPENVRPRIERMLGHGDFSFEWISVYKFQCRRMQRFLHERVIFAGDSAHQVSPF
GARGANSGLEDGENLAWKLALVLRGEAPASLLDSYEIERGQAADDNIRHSTRSTDFIAPHSQQERRLRDAALALAKEVDF
AKRMVNAGRLSTPTVYDSPLSTPDADAWGAGPKPGAAMLDAPLAADGAPMFLTEAFKSAGCDFVLLESANGVAAPVPQGV
RSLRIGKDSPLQDAEGVFAKRYDATPGSAYLLRPDGYVAARFRHPTTATIHAALARASGR

Sequences:

>Translated_540_residues
MPARESFQFGYRRHPDQDRAAPDGGREPARHPVVIVGAGPVGLSLAIDLAQRGQRVVLLDDADRIGEGSRAICFSKRALE
VWDRLGVGSRMVEKGVVWQVGKIFRRDEMVYRFDLLPETGHKMPAFINLQQYYAEAFLVDRVQELPQIDLRWRNKVIALA
QHNDHAVLTIETPDGPYRLAADYVVACDGARSALRGLVGAEFEGEVFEDQFLIADVKMTAEFPTERWFWFDPPFHAGQSA
LLHRQPDDVWRIDLQIGAEADAAVERLPENVRPRIERMLGHGDFSFEWISVYKFQCRRMQRFLHERVIFAGDSAHQVSPF
GARGANSGLEDGENLAWKLALVLRGEAPASLLDSYEIERGQAADDNIRHSTRSTDFIAPHSQQERRLRDAALALAKEVDF
AKRMVNAGRLSTPTVYDSPLSTPDADAWGAGPKPGAAMLDAPLAADGAPMFLTEAFKSAGCDFVLLESANGVAAPVPQGV
RSLRIGKDSPLQDAEGVFAKRYDATPGSAYLLRPDGYVAARFRHPTTATIHAALARASGR
>Mature_539_residues
PARESFQFGYRRHPDQDRAAPDGGREPARHPVVIVGAGPVGLSLAIDLAQRGQRVVLLDDADRIGEGSRAICFSKRALEV
WDRLGVGSRMVEKGVVWQVGKIFRRDEMVYRFDLLPETGHKMPAFINLQQYYAEAFLVDRVQELPQIDLRWRNKVIALAQ
HNDHAVLTIETPDGPYRLAADYVVACDGARSALRGLVGAEFEGEVFEDQFLIADVKMTAEFPTERWFWFDPPFHAGQSAL
LHRQPDDVWRIDLQIGAEADAAVERLPENVRPRIERMLGHGDFSFEWISVYKFQCRRMQRFLHERVIFAGDSAHQVSPFG
ARGANSGLEDGENLAWKLALVLRGEAPASLLDSYEIERGQAADDNIRHSTRSTDFIAPHSQQERRLRDAALALAKEVDFA
KRMVNAGRLSTPTVYDSPLSTPDADAWGAGPKPGAAMLDAPLAADGAPMFLTEAFKSAGCDFVLLESANGVAAPVPQGVR
SLRIGKDSPLQDAEGVFAKRYDATPGSAYLLRPDGYVAARFRHPTTATIHAALARASGR

Specific function: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=378, Percent_Identity=29.6296296296296, Blast_Score=145, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 59747; Mature: 59616

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARESFQFGYRRHPDQDRAAPDGGREPARHPVVIVGAGPVGLSLAIDLAQRGQRVVLLD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHEEEEHHHCCCEEEEEE
DADRIGEGSRAICFSKRALEVWDRLGVGSRMVEKGVVWQVGKIFRRDEMVYRFDLLPETG
CCHHCCCCCCEEEEHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHCCEEEEEECCCCCC
HKMPAFINLQQYYAEAFLVDRVQELPQIDLRWRNKVIALAQHNDHAVLTIETPDGPYRLA
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEECCEEEEEEECCCEEEEEEECCCCCEEEE
ADYVVACDGARSALRGLVGAEFEGEVFEDQFLIADVKMTAEFPTERWFWFDPPFHAGQSA
ECEEEEECCHHHHHHHHHCCCCCCCEECCEEEEEEEEEEECCCCCCEEEECCCCCCCCHH
LLHRQPDDVWRIDLQIGAEADAAVERLPENVRPRIERMLGHGDFSFEWISVYKFQCRRMQ
HHCCCCCCEEEEEEEECCCHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RFLHERVIFAGDSAHQVSPFGARGANSGLEDGENLAWKLALVLRGEAPASLLDSYEIERG
HHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHCCCC
QAADDNIRHSTRSTDFIAPHSQQERRLRDAALALAKEVDFAKRMVNAGRLSTPTVYDSPL
CCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
STPDADAWGAGPKPGAAMLDAPLAADGAPMFLTEAFKSAGCDFVLLESANGVAAPVPQGV
CCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHH
RSLRIGKDSPLQDAEGVFAKRYDATPGSAYLLRPDGYVAARFRHPTTATIHAALARASGR
HHEECCCCCCCCCCCCHHHEECCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
PARESFQFGYRRHPDQDRAAPDGGREPARHPVVIVGAGPVGLSLAIDLAQRGQRVVLLD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHEEEEHHHCCCEEEEEE
DADRIGEGSRAICFSKRALEVWDRLGVGSRMVEKGVVWQVGKIFRRDEMVYRFDLLPETG
CCHHCCCCCCEEEEHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHCCEEEEEECCCCCC
HKMPAFINLQQYYAEAFLVDRVQELPQIDLRWRNKVIALAQHNDHAVLTIETPDGPYRLA
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEECCEEEEEEECCCEEEEEEECCCCCEEEE
ADYVVACDGARSALRGLVGAEFEGEVFEDQFLIADVKMTAEFPTERWFWFDPPFHAGQSA
ECEEEEECCHHHHHHHHHCCCCCCCEECCEEEEEEEEEEECCCCCCEEEECCCCCCCCHH
LLHRQPDDVWRIDLQIGAEADAAVERLPENVRPRIERMLGHGDFSFEWISVYKFQCRRMQ
HHCCCCCCEEEEEEEECCCHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RFLHERVIFAGDSAHQVSPFGARGANSGLEDGENLAWKLALVLRGEAPASLLDSYEIERG
HHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHCCCC
QAADDNIRHSTRSTDFIAPHSQQERRLRDAALALAKEVDFAKRMVNAGRLSTPTVYDSPL
CCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
STPDADAWGAGPKPGAAMLDAPLAADGAPMFLTEAFKSAGCDFVLLESANGVAAPVPQGV
CCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHH
RSLRIGKDSPLQDAEGVFAKRYDATPGSAYLLRPDGYVAARFRHPTTATIHAALARASGR
HHEECCCCCCCCCCCCHHHEECCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA