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The map label for this gene is namA [H]

Identifier: 86748007

GI number: 86748007

Start: 1008512

End: 1009675

Strand: Direct

Name: namA [H]

Synonym: RPB_0881

Alternate gene names: 86748007

Gene position: 1008512-1009675 (Clockwise)

Preceding gene: 86747988

Following gene: 86748010

Centisome position: 18.92

GC content: 69.59

Gene sequence:

>1164_bases
ATGTCGCAGCCGCCGCTGTTCCGCCCGTTCACCTTGCGCGGCATCACCGCCAAGAACCGCATCCTGATCTCGCCGATGTG
CCAGTACTCGGCGGTCGACGGCGTCGCCAACGACTGGCACCTCGTCCATCTCGGCAAGTTCGCCCAAGGCGGCGCCGGCA
TCGTGATGGTGGAAGCCACCGCTGTCACGGCCAATGGCCGTATCACCCATGGCGACCTCGGGCTGTGGCACGACGGCCAG
ATCAAGCCGCTGGAGCGGATCGCCGCGTTCCTGCGCGACAATGGCGCGGTGCCGGCGATCCAGCTCGCCCATGCCGGGCG
CAAGGCCAGCATGCAGCGACCGTGGTACGGCAACGCCGCGCTCACCGCGGAAGATCGCGCGCGCGGCGACGAGCCGTGGC
CGATCGTCGCGCCGAGTTCGGTGCCGATGGAGGACGGCTGGCTGATGCCGCAGGAACTGTCCGAAGATCAGCTCGACGAC
CTGCTCGAGGCCTGGCGCGCCGCGACGCTGCGCGCGGTCGAGGCCGGCTTCGAAATGCTCGAAGTGCATTGCGCCCACGG
CTATCTGCTGCATTCGTTCCTGTCGCCGCTGTCCAACATGCGGACCGACGCTTACGGCGGCAGCCGCGCCGGGCGAATGC
GGTTTCCGTTGCAGGTGATCGAGACGGTGCGCGCCGTCTGGCCCGCCCCGCTGCCGCTGGCGGTGCGAGTGTCGTCGGTC
GACGGGGTCGAGGGCGGCATCGAGCTCGCCGATTCGGTGGTGTTCGCGCGCGAGGCCAAGGCGCGGGGCGCCGACATCAT
CGACTGCTCGTCGGGCGGGCTGCTCGGCTCGGCCACCGCGGCGCGCATTCCGCGGGGCTATGGCTTCCAGGTGCCGTTCG
CCGAGACCATCCGCAAGGAAGCCGAGATTCCGACCATCGCGGTCGGGCTGATCCTGCATCCGGACCAGGCGGAATCGATC
GTCGAGCAGGGCCAGGCCGATCTGGTCGCGATCGGCCGCGAGGCGCTGTTCGATCCGAACTGGACGCTGCACGCCCAGCT
CGAACTCACCGAGGACGACGAGGTGTTCGCCGACTGGCCGAAGCAATATGGCTGGTGGCTGGAACGCCGCGAGGCGGGGC
TGCGCAAGCTCGAAGGCCGCAAGCTGCCGCACCGGCGGGGGTGA

Upstream 100 bases:

>100_bases
GACGTCGGACGTATTCACGCACCGGTTGACGCTCTCGCCGTCGCAGTGCAGACCCTGAGACCGTCACGCACGTCAAACGC
CCAGAGCTGTGGAGTGTCCG

Downstream 100 bases:

>100_bases
TCTTCGTCATCGCGAGGAGCGCAGCGACGAAGCAATCCAGCTCCGTGGCGTGCGGCTGGATTGCGTCGCTTCGCTCGCAA
TGACGGAGATAGAGTCGTTG

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSQPPLFRPFTLRGITAKNRILISPMCQYSAVDGVANDWHLVHLGKFAQGGAGIVMVEATAVTANGRITHGDLGLWHDGQ
IKPLERIAAFLRDNGAVPAIQLAHAGRKASMQRPWYGNAALTAEDRARGDEPWPIVAPSSVPMEDGWLMPQELSEDQLDD
LLEAWRAATLRAVEAGFEMLEVHCAHGYLLHSFLSPLSNMRTDAYGGSRAGRMRFPLQVIETVRAVWPAPLPLAVRVSSV
DGVEGGIELADSVVFAREAKARGADIIDCSSGGLLGSATAARIPRGYGFQVPFAETIRKEAEIPTIAVGLILHPDQAESI
VEQGQADLVAIGREALFDPNWTLHAQLELTEDDEVFADWPKQYGWWLERREAGLRKLEGRKLPHRRG

Sequences:

>Translated_387_residues
MSQPPLFRPFTLRGITAKNRILISPMCQYSAVDGVANDWHLVHLGKFAQGGAGIVMVEATAVTANGRITHGDLGLWHDGQ
IKPLERIAAFLRDNGAVPAIQLAHAGRKASMQRPWYGNAALTAEDRARGDEPWPIVAPSSVPMEDGWLMPQELSEDQLDD
LLEAWRAATLRAVEAGFEMLEVHCAHGYLLHSFLSPLSNMRTDAYGGSRAGRMRFPLQVIETVRAVWPAPLPLAVRVSSV
DGVEGGIELADSVVFAREAKARGADIIDCSSGGLLGSATAARIPRGYGFQVPFAETIRKEAEIPTIAVGLILHPDQAESI
VEQGQADLVAIGREALFDPNWTLHAQLELTEDDEVFADWPKQYGWWLERREAGLRKLEGRKLPHRRG
>Mature_386_residues
SQPPLFRPFTLRGITAKNRILISPMCQYSAVDGVANDWHLVHLGKFAQGGAGIVMVEATAVTANGRITHGDLGLWHDGQI
KPLERIAAFLRDNGAVPAIQLAHAGRKASMQRPWYGNAALTAEDRARGDEPWPIVAPSSVPMEDGWLMPQELSEDQLDDL
LEAWRAATLRAVEAGFEMLEVHCAHGYLLHSFLSPLSNMRTDAYGGSRAGRMRFPLQVIETVRAVWPAPLPLAVRVSSVD
GVEGGIELADSVVFAREAKARGADIIDCSSGGLLGSATAARIPRGYGFQVPFAETIRKEAEIPTIAVGLILHPDQAESIV
EQGQADLVAIGREALFDPNWTLHAQLELTEDDEVFADWPKQYGWWLERREAGLRKLEGRKLPHRRG

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=357, Percent_Identity=29.6918767507003, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789463, Length=355, Percent_Identity=27.887323943662, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=305, Percent_Identity=26.5573770491803, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17559804, Length=250, Percent_Identity=28.4, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559802, Length=281, Percent_Identity=27.0462633451957, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17564188, Length=279, Percent_Identity=27.2401433691756, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17565138, Length=303, Percent_Identity=25.0825082508251, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17540738, Length=307, Percent_Identity=26.0586319218241, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17566914, Length=288, Percent_Identity=26.7361111111111, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321973, Length=271, Percent_Identity=28.0442804428044, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=252, Percent_Identity=25.7936507936508, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 42394; Mature: 42263

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPPLFRPFTLRGITAKNRILISPMCQYSAVDGVANDWHLVHLGKFAQGGAGIVMVEAT
CCCCCCCCCEEEECCCCCCEEEECCCHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEEE
AVTANGRITHGDLGLWHDGQIKPLERIAAFLRDNGAVPAIQLAHAGRKASMQRPWYGNAA
EEEECCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEHHCCCCCCCCCCCCCCEE
LTAEDRARGDEPWPIVAPSSVPMEDGWLMPQELSEDQLDDLLEAWRAATLRAVEAGFEML
EEEHHHCCCCCCCEEECCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EVHCAHGYLLHSFLSPLSNMRTDAYGGSRAGRMRFPLQVIETVRAVWPAPLPLAVRVSSV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCEEEEEECC
DGVEGGIELADSVVFAREAKARGADIIDCSSGGLLGSATAARIPRGYGFQVPFAETIRKE
CCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHH
AEIPTIAVGLILHPDQAESIVEQGQADLVAIGREALFDPNWTLHAQLELTEDDEVFADWP
CCCCEEEEEEEECCCHHHHHHHCCCCCEEEECHHHHCCCCCEEEEEEEECCCCCHHHHCH
KQYGWWLERREAGLRKLEGRKLPHRRG
HHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SQPPLFRPFTLRGITAKNRILISPMCQYSAVDGVANDWHLVHLGKFAQGGAGIVMVEAT
CCCCCCCCEEEECCCCCCEEEECCCHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEEE
AVTANGRITHGDLGLWHDGQIKPLERIAAFLRDNGAVPAIQLAHAGRKASMQRPWYGNAA
EEEECCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEHHCCCCCCCCCCCCCCEE
LTAEDRARGDEPWPIVAPSSVPMEDGWLMPQELSEDQLDDLLEAWRAATLRAVEAGFEML
EEEHHHCCCCCCCEEECCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EVHCAHGYLLHSFLSPLSNMRTDAYGGSRAGRMRFPLQVIETVRAVWPAPLPLAVRVSSV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCEEEEEECC
DGVEGGIELADSVVFAREAKARGADIIDCSSGGLLGSATAARIPRGYGFQVPFAETIRKE
CCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHH
AEIPTIAVGLILHPDQAESIVEQGQADLVAIGREALFDPNWTLHAQLELTEDDEVFADWP
CCCCEEEEEEEECCCHHHHHHHCCCCCEEEECHHHHCCCCCEEEEEEEECCCCCHHHHCH
KQYGWWLERREAGLRKLEGRKLPHRRG
HHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA