Click here to switch to the map view.

The map label for this gene is hipA [C]

Identifier: 86747813

GI number: 86747813

Start: 771461

End: 772702

Strand: Reverse

Name: hipA [C]

Synonym: RPB_0687

Alternate gene names: 86747813

Gene position: 772702-771461 (Counterclockwise)

Preceding gene: 86747814

Following gene: 86747811

Centisome position: 14.49

GC content: 65.22

Gene sequence:

>1242_bases
ATGACTCAGGCTGTCCTCGCGGCCGAGCGAATCCAGTCACTCGATATCTCATTGAACGACCTTCCCGTCGGCACCCTCGT
CCGGACGCCGGGTGACTACAACGCGTTCAACCTCTTGCCCGCTTACCGGGCCATGAACAATCCGCCGGTCTTCAGCCTGT
CGCTTCGCTCAGCGGATGGCGGCCTCCGGCGAGATCCCAAGCCCATACGCAGAGCACTGCCTCCGTTCTTTGCGAACCTG
CTGCCCGAAGAGAAACTGCGCGAAGCGATGGAAAAGCACCACGCCGCGTCCGTCAGGCCGGGCAACGACTTCGATCTTCT
GGCCGCGCTGGGCGGCGATCTGCCGGGAGCGGTCCGCGCCCTACCGAGTGACGGCAGCCCCGTCGTGGCCGGCCCGGAAG
CCCAAGGCCGCAACACGCGGTTCTCTCTCGCCGGTGTGCAAATGAAACTGTCGGTGATGAAGAACACCGGCAAACAAGGC
GGCATCACGCTCGCGGTCGGCGACGGGCAAGGCCAGTACATCGCCAAATTTCCCTCGCTCACGCATATCGGACTCTCGGA
GAACGAGTTCGCCCTGATGGCCCTGGCGGAAGCGCTGGGCATGGAGGTGCCCGCGCGCGAGCTCGTCGACAAGACCGAGT
TCACCGGCATCCCCGACGAGTTCACCACCCAGTCCACCGGCAAGGTGCTGCTCGTCCGCCGCTTCGACCGCGGCGATGGC
GACACGCGCGTGCATATCGAAGACTTCGCGCAGGTGTTCGGCCGCTACCCGTCCGAGAAGTACAATGGCGGCGCGTATCA
CAATATCGGCGCGGCGCTCACCAGCGGGGTCTCGTTCGATTCGGCCATCGAGTTTGCTCGGCGCCTCGCGCTCGCCGCGA
TCACCGGCAATGGCGACATGCATCTGAAGAACTGGTCGCTGCTCTATCCCGGCGACGGCCGGACGCCGATGCTGGCGCCG
GTCTACGACATGCTCTCGACGATTCCTTACCTCCCTAAGGATGGGCTCGCCCTCAGCCTCGCCGGCGAAAAGTCGCTCCA
GGCGCTCACGCCGGAGCGCTGGCGCAACTTCGCAAACCGAAGCCGTCTTCCGGAGGGCGCCGTGTTAACCGCTGTCGCCG
AGACTGCGGCCGCCGTGCGTGACAAGTGGCTCGTTCTTCCGGAACGCGACGTTGTGCCTGCGCAGGTCCGCGCGCGGATC
GATGCCCACATCGATGAAATGGTGCCGCTGCTCGACCCCTGA

Upstream 100 bases:

>100_bases
CGCAGGCGATGGTGCCCGCCATCCAGTCGATGCTGCAGCCCGCGGCCGATGATGATGATCGCCCGGCGTTCACGTCGGAT
GCCGAAGAGGAAGAACGGCC

Downstream 100 bases:

>100_bases
GCCGGGCACGTCGTGAACCGCAGTCCCCCGCGACGATCTCGAGAGCAGGCAACGGATGAAGCTCGTGGTTTCACATCAAA
GATGCTGGATGATGTCGCAG

Product: HipA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MTQAVLAAERIQSLDISLNDLPVGTLVRTPGDYNAFNLLPAYRAMNNPPVFSLSLRSADGGLRRDPKPIRRALPPFFANL
LPEEKLREAMEKHHAASVRPGNDFDLLAALGGDLPGAVRALPSDGSPVVAGPEAQGRNTRFSLAGVQMKLSVMKNTGKQG
GITLAVGDGQGQYIAKFPSLTHIGLSENEFALMALAEALGMEVPARELVDKTEFTGIPDEFTTQSTGKVLLVRRFDRGDG
DTRVHIEDFAQVFGRYPSEKYNGGAYHNIGAALTSGVSFDSAIEFARRLALAAITGNGDMHLKNWSLLYPGDGRTPMLAP
VYDMLSTIPYLPKDGLALSLAGEKSLQALTPERWRNFANRSRLPEGAVLTAVAETAAAVRDKWLVLPERDVVPAQVRARI
DAHIDEMVPLLDP

Sequences:

>Translated_413_residues
MTQAVLAAERIQSLDISLNDLPVGTLVRTPGDYNAFNLLPAYRAMNNPPVFSLSLRSADGGLRRDPKPIRRALPPFFANL
LPEEKLREAMEKHHAASVRPGNDFDLLAALGGDLPGAVRALPSDGSPVVAGPEAQGRNTRFSLAGVQMKLSVMKNTGKQG
GITLAVGDGQGQYIAKFPSLTHIGLSENEFALMALAEALGMEVPARELVDKTEFTGIPDEFTTQSTGKVLLVRRFDRGDG
DTRVHIEDFAQVFGRYPSEKYNGGAYHNIGAALTSGVSFDSAIEFARRLALAAITGNGDMHLKNWSLLYPGDGRTPMLAP
VYDMLSTIPYLPKDGLALSLAGEKSLQALTPERWRNFANRSRLPEGAVLTAVAETAAAVRDKWLVLPERDVVPAQVRARI
DAHIDEMVPLLDP
>Mature_412_residues
TQAVLAAERIQSLDISLNDLPVGTLVRTPGDYNAFNLLPAYRAMNNPPVFSLSLRSADGGLRRDPKPIRRALPPFFANLL
PEEKLREAMEKHHAASVRPGNDFDLLAALGGDLPGAVRALPSDGSPVVAGPEAQGRNTRFSLAGVQMKLSVMKNTGKQGG
ITLAVGDGQGQYIAKFPSLTHIGLSENEFALMALAEALGMEVPARELVDKTEFTGIPDEFTTQSTGKVLLVRRFDRGDGD
TRVHIEDFAQVFGRYPSEKYNGGAYHNIGAALTSGVSFDSAIEFARRLALAAITGNGDMHLKNWSLLYPGDGRTPMLAPV
YDMLSTIPYLPKDGLALSLAGEKSLQALTPERWRNFANRSRLPEGAVLTAVAETAAAVRDKWLVLPERDVVPAQVRARID
AHIDEMVPLLDP

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4mE [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=367, Percent_Identity=25.6130790190736, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 44659; Mature: 44527

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAVLAAERIQSLDISLNDLPVGTLVRTPGDYNAFNLLPAYRAMNNPPVFSLSLRSADG
CCHHHHHHHHHHHCCCEECCCCCCEEEECCCCCCCEECCHHHHHCCCCCEEEEEEECCCC
GLRRDPKPIRRALPPFFANLLPEEKLREAMEKHHAASVRPGNDFDLLAALGGDLPGAVRA
CCCCCCHHHHHCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHEE
LPSDGSPVVAGPEAQGRNTRFSLAGVQMKLSVMKNTGKQGGITLAVGDGQGQYIAKFPSL
CCCCCCCEEECCCCCCCCCEEEEECCEEEEEHHHCCCCCCCEEEEEECCCCCEEEECCCE
THIGLSENEFALMALAEALGMEVPARELVDKTEFTGIPDEFTTQSTGKVLLVRRFDRGDG
EEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHCCCCCCCEEEEEEECCCCC
DTRVHIEDFAQVFGRYPSEKYNGGAYHNIGAALTSGVSFDSAIEFARRLALAAITGNGDM
CCEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHEEEEEECCCCE
HLKNWSLLYPGDGRTPMLAPVYDMLSTIPYLPKDGLALSLAGEKSLQALTPERWRNFANR
EEECEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHCCHHHHHHHHHH
SRLPEGAVLTAVAETAAAVRDKWLVLPERDVVPAQVRARIDAHIDEMVPLLDP
CCCCCCHHHHHHHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TQAVLAAERIQSLDISLNDLPVGTLVRTPGDYNAFNLLPAYRAMNNPPVFSLSLRSADG
CHHHHHHHHHHHCCCEECCCCCCEEEECCCCCCCEECCHHHHHCCCCCEEEEEEECCCC
GLRRDPKPIRRALPPFFANLLPEEKLREAMEKHHAASVRPGNDFDLLAALGGDLPGAVRA
CCCCCCHHHHHCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHEE
LPSDGSPVVAGPEAQGRNTRFSLAGVQMKLSVMKNTGKQGGITLAVGDGQGQYIAKFPSL
CCCCCCCEEECCCCCCCCCEEEEECCEEEEEHHHCCCCCCCEEEEEECCCCCEEEECCCE
THIGLSENEFALMALAEALGMEVPARELVDKTEFTGIPDEFTTQSTGKVLLVRRFDRGDG
EEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHCCCCCCCEEEEEEECCCCC
DTRVHIEDFAQVFGRYPSEKYNGGAYHNIGAALTSGVSFDSAIEFARRLALAAITGNGDM
CCEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHEEEEEECCCCE
HLKNWSLLYPGDGRTPMLAPVYDMLSTIPYLPKDGLALSLAGEKSLQALTPERWRNFANR
EEECEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHCCHHHHHHHHHH
SRLPEGAVLTAVAETAAAVRDKWLVLPERDVVPAQVRARIDAHIDEMVPLLDP
CCCCCCHHHHHHHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]