Click here to switch to the map view.

The map label for this gene is oxyR [H]

Identifier: 86747735

GI number: 86747735

Start: 685602

End: 686540

Strand: Reverse

Name: oxyR [H]

Synonym: RPB_0609

Alternate gene names: 86747735

Gene position: 686540-685602 (Counterclockwise)

Preceding gene: 86747737

Following gene: 86747707

Centisome position: 12.88

GC content: 72.1

Gene sequence:

>939_bases
ATGGTGACGCTCCGTCAGCTCCGCTACCTCTCCGCCCTCGCCCGCTTCGGCCATTTCGGCCGGGCGGCGGAAGCCTGCGC
CGTGACCCAGCCGGCGCTGTCGATGCAGATCGCCGATCTGGAGCGCACGCTCGGGGTCAAGGTTGTCGAACGCCGGCCCG
GCGAGGTGTTCCTGACCGAGATCGGCCGCGAGATCGCCCGCCGCGGCGAGGACCTGCTGACGGCGTCGCGCGATCTGGTG
GATTTCGCCCGCCACCGCGCCCAGCCGCTGACCGGCCGGCTGACGCTCGGGGTGATTCCGTCGCTGGCGCCGTATCTGCT
GCCGAAGCTGCTGCCGCTGCTGCAGCAGCGCTACCCCGAATTGCGGCTGGAGCTGCGCGAGAGCCAGACCCGGCAATTGG
TCACCGAGGTCGGCAGCGGCGCACTCGACGCCGCCCTGCTGGCGCTGCCCGCCGGCAACCGCGAGCTCGATGCGATCACG
CTGTTCGACGACGAATTCCTGCTGGCGGTGCCGGCCGACGACCCGCGGCCCGAGACCGCGACGGTGGCGGTCGACGAGAT
CGACCAGTCGCGGCTGATCCTGCTCGAAGACGGCCACTGCCTGCGCGACCAGGCGCTGGCGTTCTGCGCCACCGCGCGCA
ACCGCGCCATCGCCATCGGCGGCACCAGCACCACCACGTTCGGCGCCTCCAGCCTCACCACGGTGATCCAGATGGTCGCC
GGCGGCTACGGCGTGACGCTGATTCCGCAGATCGCCGCCGAGATCGAGCGCCGCGACACCAGGGTGAAATTCCTGCGGCT
GCGGCGGCCGCAGCCCGGCCGCACCATCGGCCTGGCGTTCCGCAAGACCTCGCCGCGCCGCCAGGACTTCGAAGCGCTGG
GCGAGGTGGTGCGGGAGGGAGTGGGCGGCCGCAGCAGCATGGCGCAGCCGGCAGCCTGA

Upstream 100 bases:

>100_bases
CCGCTGGATCAGCGTCGCCCGGCCCGCGCAGACTGGATCAGTTCTACGATCAGGTCCAGTCGAATTGATTTTGGATACCG
ATCAGATTATCTGATCGTCT

Downstream 100 bases:

>100_bases
TCGCGATACGGCGAGCGGCAGCGATCCCTCGGCTCAGCCGCCCGCCGCCATCGCGGCGGCTTCGGCGGCGGCGCGCTGCA
TGCTCGACGACATTTCGCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MVTLRQLRYLSALARFGHFGRAAEACAVTQPALSMQIADLERTLGVKVVERRPGEVFLTEIGREIARRGEDLLTASRDLV
DFARHRAQPLTGRLTLGVIPSLAPYLLPKLLPLLQQRYPELRLELRESQTRQLVTEVGSGALDAALLALPAGNRELDAIT
LFDDEFLLAVPADDPRPETATVAVDEIDQSRLILLEDGHCLRDQALAFCATARNRAIAIGGTSTTTFGASSLTTVIQMVA
GGYGVTLIPQIAAEIERRDTRVKFLRLRRPQPGRTIGLAFRKTSPRRQDFEALGEVVREGVGGRSSMAQPAA

Sequences:

>Translated_312_residues
MVTLRQLRYLSALARFGHFGRAAEACAVTQPALSMQIADLERTLGVKVVERRPGEVFLTEIGREIARRGEDLLTASRDLV
DFARHRAQPLTGRLTLGVIPSLAPYLLPKLLPLLQQRYPELRLELRESQTRQLVTEVGSGALDAALLALPAGNRELDAIT
LFDDEFLLAVPADDPRPETATVAVDEIDQSRLILLEDGHCLRDQALAFCATARNRAIAIGGTSTTTFGASSLTTVIQMVA
GGYGVTLIPQIAAEIERRDTRVKFLRLRRPQPGRTIGLAFRKTSPRRQDFEALGEVVREGVGGRSSMAQPAA
>Mature_312_residues
MVTLRQLRYLSALARFGHFGRAAEACAVTQPALSMQIADLERTLGVKVVERRPGEVFLTEIGREIARRGEDLLTASRDLV
DFARHRAQPLTGRLTLGVIPSLAPYLLPKLLPLLQQRYPELRLELRESQTRQLVTEVGSGALDAALLALPAGNRELDAIT
LFDDEFLLAVPADDPRPETATVAVDEIDQSRLILLEDGHCLRDQALAFCATARNRAIAIGGTSTTTFGASSLTTVIQMVA
GGYGVTLIPQIAAEIERRDTRVKFLRLRRPQPGRTIGLAFRKTSPRRQDFEALGEVVREGVGGRSSMAQPAA

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=303, Percent_Identity=39.9339933993399, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1788887, Length=297, Percent_Identity=28.2828282828283, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI157672245, Length=287, Percent_Identity=29.616724738676, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787879, Length=264, Percent_Identity=27.6515151515151, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788748, Length=300, Percent_Identity=24.3333333333333, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693105, Length=303, Percent_Identity=25.4125412541254, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787530, Length=262, Percent_Identity=25.1908396946565, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI2367136, Length=282, Percent_Identity=24.822695035461, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789506, Length=248, Percent_Identity=24.1935483870968, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=167, Percent_Identity=26.3473053892216, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788297, Length=258, Percent_Identity=25.968992248062, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790208, Length=271, Percent_Identity=26.5682656826568, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34099; Mature: 34099

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLRQLRYLSALARFGHFGRAAEACAVTQPALSMQIADLERTLGVKVVERRPGEVFLTE
CCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHH
IGREIARRGEDLLTASRDLVDFARHRAQPLTGRLTLGVIPSLAPYLLPKLLPLLQQRYPE
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCHH
LRLELRESQTRQLVTEVGSGALDAALLALPAGNRELDAITLFDDEFLLAVPADDPRPETA
HHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCEEEEEEECCCEEEEECCCCCCCCEE
TVAVDEIDQSRLILLEDGHCLRDQALAFCATARNRAIAIGGTSTTTFGASSLTTVIQMVA
EEEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHH
GGYGVTLIPQIAAEIERRDTRVKFLRLRRPQPGRTIGLAFRKTSPRRQDFEALGEVVREG
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHC
VGGRSSMAQPAA
CCCCCCCCCCCC
>Mature Secondary Structure
MVTLRQLRYLSALARFGHFGRAAEACAVTQPALSMQIADLERTLGVKVVERRPGEVFLTE
CCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHH
IGREIARRGEDLLTASRDLVDFARHRAQPLTGRLTLGVIPSLAPYLLPKLLPLLQQRYPE
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCHH
LRLELRESQTRQLVTEVGSGALDAALLALPAGNRELDAITLFDDEFLLAVPADDPRPETA
HHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCEEEEEEECCCEEEEECCCCCCCCEE
TVAVDEIDQSRLILLEDGHCLRDQALAFCATARNRAIAIGGTSTTTFGASSLTTVIQMVA
EEEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHH
GGYGVTLIPQIAAEIERRDTRVKFLRLRRPQPGRTIGLAFRKTSPRRQDFEALGEVVREG
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHC
VGGRSSMAQPAA
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]