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The map label for this gene is tlyC [H]

Identifier: 86747719

GI number: 86747719

Start: 665372

End: 666502

Strand: Direct

Name: tlyC [H]

Synonym: RPB_0593

Alternate gene names: 86747719

Gene position: 665372-666502 (Clockwise)

Preceding gene: 86747718

Following gene: 86747720

Centisome position: 12.48

GC content: 69.76

Gene sequence:

>1131_bases
ATGCCGGACGGCGACAGAGCGCAGAGCGCAGCGCAGCCAGCGGAGCAGGACTTACCACGCGGCCAGCAACTGCCGGCGGT
GGTGCATCAGGGCGAGGTGCTGCGGCCGGCCGGCGCGGCCTGGCTGATGCGCGCGATCCGTTCGCTGTTCGGCTGGAAGC
CCGGCTCGGTGCGCGACGACCTGCAGGTCGTGCTAGACACCAGCCCGGCGGACGACACCGGCTTCAGCGCGCTCGAGCGC
ACCATGCTGCGCAACATCCTCGGGCTGCACGAGCGTCGCATCGCCGACGTCATGGTGCATCGCGCCGACATCGTCGCGAT
CAAGCAGGACATCGCGCTCGGCGAACTGATGAGCCTGTTCGAGGGCGCGGCGCATTCGCGCCTCGTGGTCTATGACGAGA
CGCTCGACGATCCGGTCGGCCTGGTCCACATCCGCGACCTCGTCGCGTTCATGACCGCCAGGGCCAAGGTGGCGCCCGAG
ACCGTGGCCAAGCGCAAGAAGGCGCTGCCGGCCGGGCTCGACCTGCGCGCGATCGATCTGAAGATGCCGCTGACCGAGAC
CGGCATCATCCGCAAGCTGCTGTACGTGCCGCCGTCGATGCGCGCGATCGATCTGCTGGCGCAGATGCAGGCCGCCCGCA
TCCATCTGGCGCTGGTGGTCGACGAATATGGCGGCACCGACGGCCTGGTCTCGATCGAGGACATCGTCGAGCAGATCGTC
GGCGAGATCGACGACGAGCACGACAGCGCCGAGCCGCCGTCGATCGTGCAGCAGGCCGACGGCTCGTTCGTCGCCGACGC
CCGCACCAGCCTCGAGGATGCGCGCGAGATGATCGGCGACGGCTTCGTCACCGGCGAAGCCGGCGAGGACGTCGAGACGC
TCGGCGGCTATCTGGTCAATCATGTCGGCCGGCTGCCGGTGCGCGGCGAAGTGATCTCCGGCCCCGGCAATTACGAGATC
GAGGTGCTGGACGCCGACCCGCGCCGCGTCAAGCGGCTGCGCATCGGCATTCGCAAGGAACGCCCCGTCGTGCGGCCGCG
CGAGACGCGGCGGCGCGAGCCGGCCTCCGATCAGGCCGCCACCACACCTGCCGATCCGACCCATCCGAATCCTTCGCCGC
CCGGCGACTGA

Upstream 100 bases:

>100_bases
ACCGACGCCGAGGCCGAGACGATGGAAGCCGCCGAGCGCCGCATTCTCGCCGGCCTCGGCATTCCGGATCCCTATGCCGA
TCAGGATCGGGTGAGCTGAC

Downstream 100 bases:

>100_bases
GCGAGCACGCCGTGACATTGCCAAATCTGCTGAGCCGAGCCGCATCGAGCATCATTCTCGCATGGGGCTGGAAGCGGGCG
GCCATCGCCGCCATTGCGGG

Product: HlyC/CorC family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MPDGDRAQSAAQPAEQDLPRGQQLPAVVHQGEVLRPAGAAWLMRAIRSLFGWKPGSVRDDLQVVLDTSPADDTGFSALER
TMLRNILGLHERRIADVMVHRADIVAIKQDIALGELMSLFEGAAHSRLVVYDETLDDPVGLVHIRDLVAFMTARAKVAPE
TVAKRKKALPAGLDLRAIDLKMPLTETGIIRKLLYVPPSMRAIDLLAQMQAARIHLALVVDEYGGTDGLVSIEDIVEQIV
GEIDDEHDSAEPPSIVQQADGSFVADARTSLEDAREMIGDGFVTGEAGEDVETLGGYLVNHVGRLPVRGEVISGPGNYEI
EVLDADPRRVKRLRIGIRKERPVVRPRETRRREPASDQAATTPADPTHPNPSPPGD

Sequences:

>Translated_376_residues
MPDGDRAQSAAQPAEQDLPRGQQLPAVVHQGEVLRPAGAAWLMRAIRSLFGWKPGSVRDDLQVVLDTSPADDTGFSALER
TMLRNILGLHERRIADVMVHRADIVAIKQDIALGELMSLFEGAAHSRLVVYDETLDDPVGLVHIRDLVAFMTARAKVAPE
TVAKRKKALPAGLDLRAIDLKMPLTETGIIRKLLYVPPSMRAIDLLAQMQAARIHLALVVDEYGGTDGLVSIEDIVEQIV
GEIDDEHDSAEPPSIVQQADGSFVADARTSLEDAREMIGDGFVTGEAGEDVETLGGYLVNHVGRLPVRGEVISGPGNYEI
EVLDADPRRVKRLRIGIRKERPVVRPRETRRREPASDQAATTPADPTHPNPSPPGD
>Mature_375_residues
PDGDRAQSAAQPAEQDLPRGQQLPAVVHQGEVLRPAGAAWLMRAIRSLFGWKPGSVRDDLQVVLDTSPADDTGFSALERT
MLRNILGLHERRIADVMVHRADIVAIKQDIALGELMSLFEGAAHSRLVVYDETLDDPVGLVHIRDLVAFMTARAKVAPET
VAKRKKALPAGLDLRAIDLKMPLTETGIIRKLLYVPPSMRAIDLLAQMQAARIHLALVVDEYGGTDGLVSIEDIVEQIVG
EIDDEHDSAEPPSIVQQADGSFVADARTSLEDAREMIGDGFVTGEAGEDVETLGGYLVNHVGRLPVRGEVISGPGNYEIE
VLDADPRRVKRLRIGIRKERPVVRPRETRRREPASDQAATTPADPTHPNPSPPGD

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=295, Percent_Identity=27.1186440677966, Blast_Score=105, Evalue=8e-23,
Organism=Escherichia coli, GI1786879, Length=297, Percent_Identity=30.3030303030303, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI87082033, Length=269, Percent_Identity=28.996282527881, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693175, Length=306, Percent_Identity=24.5098039215686, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788119, Length=274, Percent_Identity=26.2773722627737, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790664, Length=258, Percent_Identity=21.7054263565891, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 40941; Mature: 40810

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDGDRAQSAAQPAEQDLPRGQQLPAVVHQGEVLRPAGAAWLMRAIRSLFGWKPGSVRDD
CCCCHHHHHHCCCHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
LQVVLDTSPADDTGFSALERTMLRNILGLHERRIADVMVHRADIVAIKQDIALGELMSLF
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGAAHSRLVVYDETLDDPVGLVHIRDLVAFMTARAKVAPETVAKRKKALPAGLDLRAIDL
HCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEE
KMPLTETGIIRKLLYVPPSMRAIDLLAQMQAARIHLALVVDEYGGTDGLVSIEDIVEQIV
ECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCCEEHHHHHHHHH
GEIDDEHDSAEPPSIVQQADGSFVADARTSLEDAREMIGDGFVTGEAGEDVETLGGYLVN
HHCCCCCCCCCCCHHHHHCCCCEEHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHH
HVGRLPVRGEVISGPGNYEIEVLDADPRRVKRLRIGIRKERPVVRPRETRRREPASDQAA
HHCCCCCCCEEECCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCC
TTPADPTHPNPSPPGD
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDGDRAQSAAQPAEQDLPRGQQLPAVVHQGEVLRPAGAAWLMRAIRSLFGWKPGSVRDD
CCCHHHHHHCCCHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
LQVVLDTSPADDTGFSALERTMLRNILGLHERRIADVMVHRADIVAIKQDIALGELMSLF
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGAAHSRLVVYDETLDDPVGLVHIRDLVAFMTARAKVAPETVAKRKKALPAGLDLRAIDL
HCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEE
KMPLTETGIIRKLLYVPPSMRAIDLLAQMQAARIHLALVVDEYGGTDGLVSIEDIVEQIV
ECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCCEEHHHHHHHHH
GEIDDEHDSAEPPSIVQQADGSFVADARTSLEDAREMIGDGFVTGEAGEDVETLGGYLVN
HHCCCCCCCCCCCHHHHHCCCCEEHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHH
HVGRLPVRGEVISGPGNYEIEVLDADPRRVKRLRIGIRKERPVVRPRETRRREPASDQAA
HHCCCCCCCEEECCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCC
TTPADPTHPNPSPPGD
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA