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The map label for this gene is chvG [H]

Identifier: 86747590

GI number: 86747590

Start: 511624

End: 513423

Strand: Direct

Name: chvG [H]

Synonym: RPB_0464

Alternate gene names: 86747590

Gene position: 511624-513423 (Clockwise)

Preceding gene: 86747589

Following gene: 86747591

Centisome position: 9.6

GC content: 68.17

Gene sequence:

>1800_bases
TTGCTGGATCGCACCGCGGCTGATCAGGAAGCCCGCGACGGGGACGACGCCGCCGCGCAGGACGAGACCGCGACCCGCGC
CCGGCCGTGGCAGCGGCCGTTCGCCTGGGTGCGGCGTGCCGGGCAGTTCTTTTTCACGCTGAGCTTCTCCAGCCTGACGC
GGCGCATCCTGTCGCTCAACCTCGCCGGCCTGATGGCGCTGTCGGCGAGCATTCTGTATCTGTCGCAGTTCCGCGCCGGC
CTGATCGACGCCCGCGCGCAGAGCCTGCTGGTGCAGGCCGAAATCATCGCCGGCGCGATCGCCGCCTCCGCCACCGTCGA
AACCAACACCATCACCATCGATCCGGACCGGCTGCTCGATCTCAAGCCCGGCGAGACCTACGGCCCGCCGGACGAATACG
CGGTGCTGGATTTCCCGATCAATCCCGAGCGCGTCGCGCCGGTGCTGCGGCGGCTGATCTCGCCGACCAAGACGAGGGCC
CGCATCTATGACCGCGATGGCGTGCTGATTCTCGACAGCCGCAGCCTGTACGGCCGCGGCGACGTGATGCGGTTCGACCT
GCCGCCGCCGACGGCGGAGAAGCCCGGCTTCGTCGAGCGCGCGATGATCGCGATCCGCACCTGGTTCAATCGCGGCGATC
TGCCGCTGTATCGCGAACTCGGGCCCGAGAACGGCAACGGCTATCAGGAGGTCGCCGATTCGCTGAAGGGCCAGAAGAAC
TCGATGGTGCGGATCAACGACCGCGGCGAGGTGATCGTCTCGGTCGCGGTGCCGGTGCAGCGTTTCCGCGCCATTCACGG
CGCCTTGATGCTGTCGACCCAGGGCGACGACATCGACCAGATGGTGACCGCCGAACGGCTGGCGATCCTGAAGATCTTCG
GGCTGGCGGCGATCGTGATGTTCGTGCTGTCGGTGCTGCTGGCCTCGACCATCGCGGGTCCGGTGCGCAGGCTCGCCGAC
GCCGCCGAGCGGGTCCGCCGCCGCATTCGCGCCCGCGTCGAGATTCCGGATTTCACCACGAGGCGCGACGAGATCGGGCA
TCTGTCGGGCGCGCTGCGGGAGATGACCGATTCGCTGTACAACCGCATCGAGGCGATCGAGCGCTTCGCCGCCGACGTCT
CGCACGAACTGAAGAACCCGCTGACCTCGCTGCGTTCGGCGGTCGAGACGCTGCCGCTGGCCAAGAATGCCAACAGCCGG
TCGCGGCTGCTCGCGGTGATCGAGCACGACGTCAAACGGCTCGACCGGCTGATCTCGGACATCTCCGACGCCAGCCGGCT
CGACGCCGAATTGCAGCGCCAGGACGCCGCCCCGGTCGATCTGCGCCGGCTGCTGACGACGCTGACCTTGGTCGCCAACG
AAACCCGGCTCGGCAACAATGCGCTGGTCGAGGTGCGGTTCGAGGGACCGCCGAACGAGCCGTTCTCGGTGCCCGGCCAT
GATTCGCGGCTCGGCCAGGTGATCTCCAACCTGCTGTCGAATGCGCAGTCGTTCTCCCGCGAGGGCGGCAAGGTTCAGAT
CGTCTGCCGCCGCCGCAAGACCGAGATCGAGATCGTGGTCGACGACGAGGGCCCGGGCATCCGCGACGACGCCTTCGACA
AGATCTTCGAGCGTTTCTACACCGACCGGCCGCATCAGGGCTTCGGCCAGAATTCCGGGCTCGGCCTGTCGATCTCCCGG
CAGATCGTCGAGGCCCATGGTGGCAAAATCCGCGCCGAGAATCGCCCCGGCCCGCGCGATGCGGAGGGCGAGCCGACCAT
CGCCGGCGCCCGCTTCGTGGTCCGGCTGCCGTCGACATGA

Upstream 100 bases:

>100_bases
ATATGCTCGCGCATGATCCCGAAAAGGGAATACCGGTTTTCGGAGACGATCATGCGCCGACGACAATTGCTCATCGCCAA
TCATCGGGCAGGCTTGGCCA

Downstream 100 bases:

>100_bases
CCGCGCCGGGCGCGCCCAGCATTCACGCCTCCGCCGTCCGGGTCGGCGACCGCGCGGTGCTGATCCGCGGGCCCTCCGGC
TCCGGTAAATCCCGCCTCGC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Histidine kinase sensory protein ExoS [H]

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MLDRTAADQEARDGDDAAAQDETATRARPWQRPFAWVRRAGQFFFTLSFSSLTRRILSLNLAGLMALSASILYLSQFRAG
LIDARAQSLLVQAEIIAGAIAASATVETNTITIDPDRLLDLKPGETYGPPDEYAVLDFPINPERVAPVLRRLISPTKTRA
RIYDRDGVLILDSRSLYGRGDVMRFDLPPPTAEKPGFVERAMIAIRTWFNRGDLPLYRELGPENGNGYQEVADSLKGQKN
SMVRINDRGEVIVSVAVPVQRFRAIHGALMLSTQGDDIDQMVTAERLAILKIFGLAAIVMFVLSVLLASTIAGPVRRLAD
AAERVRRRIRARVEIPDFTTRRDEIGHLSGALREMTDSLYNRIEAIERFAADVSHELKNPLTSLRSAVETLPLAKNANSR
SRLLAVIEHDVKRLDRLISDISDASRLDAELQRQDAAPVDLRRLLTTLTLVANETRLGNNALVEVRFEGPPNEPFSVPGH
DSRLGQVISNLLSNAQSFSREGGKVQIVCRRRKTEIEIVVDDEGPGIRDDAFDKIFERFYTDRPHQGFGQNSGLGLSISR
QIVEAHGGKIRAENRPGPRDAEGEPTIAGARFVVRLPST

Sequences:

>Translated_599_residues
MLDRTAADQEARDGDDAAAQDETATRARPWQRPFAWVRRAGQFFFTLSFSSLTRRILSLNLAGLMALSASILYLSQFRAG
LIDARAQSLLVQAEIIAGAIAASATVETNTITIDPDRLLDLKPGETYGPPDEYAVLDFPINPERVAPVLRRLISPTKTRA
RIYDRDGVLILDSRSLYGRGDVMRFDLPPPTAEKPGFVERAMIAIRTWFNRGDLPLYRELGPENGNGYQEVADSLKGQKN
SMVRINDRGEVIVSVAVPVQRFRAIHGALMLSTQGDDIDQMVTAERLAILKIFGLAAIVMFVLSVLLASTIAGPVRRLAD
AAERVRRRIRARVEIPDFTTRRDEIGHLSGALREMTDSLYNRIEAIERFAADVSHELKNPLTSLRSAVETLPLAKNANSR
SRLLAVIEHDVKRLDRLISDISDASRLDAELQRQDAAPVDLRRLLTTLTLVANETRLGNNALVEVRFEGPPNEPFSVPGH
DSRLGQVISNLLSNAQSFSREGGKVQIVCRRRKTEIEIVVDDEGPGIRDDAFDKIFERFYTDRPHQGFGQNSGLGLSISR
QIVEAHGGKIRAENRPGPRDAEGEPTIAGARFVVRLPST
>Mature_599_residues
MLDRTAADQEARDGDDAAAQDETATRARPWQRPFAWVRRAGQFFFTLSFSSLTRRILSLNLAGLMALSASILYLSQFRAG
LIDARAQSLLVQAEIIAGAIAASATVETNTITIDPDRLLDLKPGETYGPPDEYAVLDFPINPERVAPVLRRLISPTKTRA
RIYDRDGVLILDSRSLYGRGDVMRFDLPPPTAEKPGFVERAMIAIRTWFNRGDLPLYRELGPENGNGYQEVADSLKGQKN
SMVRINDRGEVIVSVAVPVQRFRAIHGALMLSTQGDDIDQMVTAERLAILKIFGLAAIVMFVLSVLLASTIAGPVRRLAD
AAERVRRRIRARVEIPDFTTRRDEIGHLSGALREMTDSLYNRIEAIERFAADVSHELKNPLTSLRSAVETLPLAKNANSR
SRLLAVIEHDVKRLDRLISDISDASRLDAELQRQDAAPVDLRRLLTTLTLVANETRLGNNALVEVRFEGPPNEPFSVPGH
DSRLGQVISNLLSNAQSFSREGGKVQIVCRRRKTEIEIVVDDEGPGIRDDAFDKIFERFYTDRPHQGFGQNSGLGLSISR
QIVEAHGGKIRAENRPGPRDAEGEPTIAGARFVVRLPST

Specific function: Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Activates ChvI by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=272, Percent_Identity=31.9852941176471, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1790346, Length=295, Percent_Identity=28.135593220339, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1790436, Length=303, Percent_Identity=26.7326732673267, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=28.7937743190661, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786783, Length=312, Percent_Identity=25.9615384615385, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1789149, Length=346, Percent_Identity=25.7225433526012, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789403, Length=284, Percent_Identity=29.2253521126761, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI48994928, Length=217, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=244, Percent_Identity=28.2786885245902, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=27.8969957081545, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788549, Length=271, Percent_Identity=28.4132841328413, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=29.7872340425532, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787374, Length=310, Percent_Identity=28.3870967741935, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=249, Percent_Identity=28.5140562248996, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66363; Mature: 66363

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRTAADQEARDGDDAAAQDETATRARPWQRPFAWVRRAGQFFFTLSFSSLTRRILSLN
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHH
LAGLMALSASILYLSQFRAGLIDARAQSLLVQAEIIAGAIAASATVETNTITIDPDRLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEECHHHEEE
LKPGETYGPPDEYAVLDFPINPERVAPVLRRLISPTKTRARIYDRDGVLILDSRSLYGRG
CCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHEEECCCCEEEEECCCCCCCC
DVMRFDLPPPTAEKPGFVERAMIAIRTWFNRGDLPLYRELGPENGNGYQEVADSLKGQKN
CEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCC
SMVRINDRGEVIVSVAVPVQRFRAIHGALMLSTQGDDIDQMVTAERLAILKIFGLAAIVM
CEEEECCCCCEEEEECCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
FVLSVLLASTIAGPVRRLADAAERVRRRIRARVEIPDFTTRRDEIGHLSGALREMTDSLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHH
NRIEAIERFAADVSHELKNPLTSLRSAVETLPLAKNANSRSRLLAVIEHDVKRLDRLISD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ISDASRLDAELQRQDAAPVDLRRLLTTLTLVANETRLGNNALVEVRFEGPPNEPFSVPGH
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCC
DSRLGQVISNLLSNAQSFSREGGKVQIVCRRRKTEIEIVVDDEGPGIRDDAFDKIFERFY
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHH
TDRPHQGFGQNSGLGLSISRQIVEAHGGKIRAENRPGPRDAEGEPTIAGARFVVRLPST
CCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEECCEEEEECCCC
>Mature Secondary Structure
MLDRTAADQEARDGDDAAAQDETATRARPWQRPFAWVRRAGQFFFTLSFSSLTRRILSLN
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHH
LAGLMALSASILYLSQFRAGLIDARAQSLLVQAEIIAGAIAASATVETNTITIDPDRLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEECHHHEEE
LKPGETYGPPDEYAVLDFPINPERVAPVLRRLISPTKTRARIYDRDGVLILDSRSLYGRG
CCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHEEECCCCEEEEECCCCCCCC
DVMRFDLPPPTAEKPGFVERAMIAIRTWFNRGDLPLYRELGPENGNGYQEVADSLKGQKN
CEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCC
SMVRINDRGEVIVSVAVPVQRFRAIHGALMLSTQGDDIDQMVTAERLAILKIFGLAAIVM
CEEEECCCCCEEEEECCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
FVLSVLLASTIAGPVRRLADAAERVRRRIRARVEIPDFTTRRDEIGHLSGALREMTDSLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHH
NRIEAIERFAADVSHELKNPLTSLRSAVETLPLAKNANSRSRLLAVIEHDVKRLDRLISD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ISDASRLDAELQRQDAAPVDLRRLLTTLTLVANETRLGNNALVEVRFEGPPNEPFSVPGH
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCC
DSRLGQVISNLLSNAQSFSREGGKVQIVCRRRKTEIEIVVDDEGPGIRDDAFDKIFERFY
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHH
TDRPHQGFGQNSGLGLSISRQIVEAHGGKIRAENRPGPRDAEGEPTIAGARFVVRLPST
CCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEECCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9422587; 11481430; 7559334 [H]