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The map label for this gene is blh [H]

Identifier: 86747583

GI number: 86747583

Start: 503622

End: 504548

Strand: Reverse

Name: blh [H]

Synonym: RPB_0457

Alternate gene names: 86747583

Gene position: 504548-503622 (Counterclockwise)

Preceding gene: 86747587

Following gene: 86747582

Centisome position: 9.46

GC content: 68.07

Gene sequence:

>927_bases
GTGACCAGCCCTTCTTCGCCGCAGATCCCCTCGCAGGTCTCCTCGCCGCGGATTCGCGCGTTTTTCGACGCGCCGACCAA
CACCATCAGCTATCTGGTGTCGGACCCCGCCACCCGCCGCGCCGCGGTGATCGATCCGGTGCTCGACTATGATCACCGCG
ACGGTTCCGTCGACGTGCGCTCGGCCGATGCGATCCTGCAGGCCGCCCGGGACGACGGCCTGACGATCGACTGGGTGCTG
GAAACCCACGCCCATGCCGACCACCTCTCCGGTGCGCCCTACATCAAGGCCAAGACCGGGGCGCGGATCGGCATCGGCGA
GCACATCAAGGATGTGCAGCGGATTTTCCGGCCGATGTTCAACGCCGACGATCTGCGCACCGACGGCAGCGATTTCGATC
ATCTGTTCAAGGACGGCGAGCGGTTTTCGATCGGCGATCTGCCGGTCGAGGTGCTGCACACGCCGGGGCACACGCCCGCC
GACATCGCCTACCGGATCGGCGACGACGCGGTGTTCGTCGGCGACACGCTGTTCATGCCGGATTACGGCACGGCGCGGGC
GGATTTCCCCGGTGGCGACGCGCACCAGCTCTATCGCTCGATCCAGAAGCTGCTGGCGCTGCCGCCGCAGACCCGGCTGT
TCATGTGCCACGACTACAAGGCGCCCGGCCGCGACGACTATGCGTGGGAGACCACCGTGCAGGCGCAGCGCGACGGCAAT
GTGCATCTGCGCGGCGGCGTCAGCGAGCAGCAATTCGTCGACATGCGCAACGCCCGCGACGCCACGCTGAGCGCGCCGAC
GCTGCTGCTGCCGTCGATCCAGGTCAACATCCGCGCCGGCCGCTTCCCCAAGGCGCAGCAGAACGGCGTGCATTATCTGC
TGCTGCCGGTGCATGCCCGCCCCGGCGCCGAGGCGGGGCTGAGCTGA

Upstream 100 bases:

>100_bases
TCAGCATGAAATTCTACAAATCGGCGCTTGCACGGGTGGGATATGCTAATAGATAGGCTTGGGGCGCAACAGCCATTCTA
CCGGATCAGGGAAATTGCTC

Downstream 100 bases:

>100_bases
GCCGCCCGGCTCGGCTGTACGCGGCCGATCGGACAACCCTTAACGCGGCGTTAACCGGCGCTGGTGTGAAGTGTTGCTGA
ATATTTTTCGCGCGGCAGGG

Product: Beta-lactamase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTSPSSPQIPSQVSSPRIRAFFDAPTNTISYLVSDPATRRAAVIDPVLDYDHRDGSVDVRSADAILQAARDDGLTIDWVL
ETHAHADHLSGAPYIKAKTGARIGIGEHIKDVQRIFRPMFNADDLRTDGSDFDHLFKDGERFSIGDLPVEVLHTPGHTPA
DIAYRIGDDAVFVGDTLFMPDYGTARADFPGGDAHQLYRSIQKLLALPPQTRLFMCHDYKAPGRDDYAWETTVQAQRDGN
VHLRGGVSEQQFVDMRNARDATLSAPTLLLPSIQVNIRAGRFPKAQQNGVHYLLLPVHARPGAEAGLS

Sequences:

>Translated_308_residues
MTSPSSPQIPSQVSSPRIRAFFDAPTNTISYLVSDPATRRAAVIDPVLDYDHRDGSVDVRSADAILQAARDDGLTIDWVL
ETHAHADHLSGAPYIKAKTGARIGIGEHIKDVQRIFRPMFNADDLRTDGSDFDHLFKDGERFSIGDLPVEVLHTPGHTPA
DIAYRIGDDAVFVGDTLFMPDYGTARADFPGGDAHQLYRSIQKLLALPPQTRLFMCHDYKAPGRDDYAWETTVQAQRDGN
VHLRGGVSEQQFVDMRNARDATLSAPTLLLPSIQVNIRAGRFPKAQQNGVHYLLLPVHARPGAEAGLS
>Mature_307_residues
TSPSSPQIPSQVSSPRIRAFFDAPTNTISYLVSDPATRRAAVIDPVLDYDHRDGSVDVRSADAILQAARDDGLTIDWVLE
THAHADHLSGAPYIKAKTGARIGIGEHIKDVQRIFRPMFNADDLRTDGSDFDHLFKDGERFSIGDLPVEVLHTPGHTPAD
IAYRIGDDAVFVGDTLFMPDYGTARADFPGGDAHQLYRSIQKLLALPPQTRLFMCHDYKAPGRDDYAWETTVQAQRDGNV
HLRGGVSEQQFVDMRNARDATLSAPTLLLPSIQVNIRAGRFPKAQQNGVHYLLLPVHARPGAEAGLS

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=265, Percent_Identity=26.7924528301887, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI94538322, Length=204, Percent_Identity=28.921568627451, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI94538320, Length=204, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI46361987, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI14150041, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787158, Length=184, Percent_Identity=32.6086956521739, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538952, Length=270, Percent_Identity=27.037037037037, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI221330176, Length=267, Percent_Identity=28.4644194756554, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 33857; Mature: 33726

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPSSPQIPSQVSSPRIRAFFDAPTNTISYLVSDPATRRAAVIDPVLDYDHRDGSVDVR
CCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCEEECHHHCCCCCCCCEEEH
SADAILQAARDDGLTIDWVLETHAHADHLSGAPYIKAKTGARIGIGEHIKDVQRIFRPMF
HHHHHHHHHCCCCCEEEEEEECCCCHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHC
NADDLRTDGSDFDHLFKDGERFSIGDLPVEVLHTPGHTPADIAYRIGDDAVFVGDTLFMP
CCCCCCCCCCCHHHHHCCCCEEEECCCCEEEEECCCCCCHHEEEEECCCEEEECCEEECC
DYGTARADFPGGDAHQLYRSIQKLLALPPQTRLFMCHDYKAPGRDDYAWETTVQAQRDGN
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCC
VHLRGGVSEQQFVDMRNARDATLSAPTLLLPSIQVNIRAGRFPKAQQNGVHYLLLPVHAR
EEEECCCCHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCEEEEEEEECC
PGAEAGLS
CCCCCCCC
>Mature Secondary Structure 
TSPSSPQIPSQVSSPRIRAFFDAPTNTISYLVSDPATRRAAVIDPVLDYDHRDGSVDVR
CCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCEEECHHHCCCCCCCCEEEH
SADAILQAARDDGLTIDWVLETHAHADHLSGAPYIKAKTGARIGIGEHIKDVQRIFRPMF
HHHHHHHHHCCCCCEEEEEEECCCCHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHC
NADDLRTDGSDFDHLFKDGERFSIGDLPVEVLHTPGHTPADIAYRIGDDAVFVGDTLFMP
CCCCCCCCCCCHHHHHCCCCEEEECCCCEEEEECCCCCCHHEEEEECCCEEEECCEEECC
DYGTARADFPGGDAHQLYRSIQKLLALPPQTRLFMCHDYKAPGRDDYAWETTVQAQRDGN
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCC
VHLRGGVSEQQFVDMRNARDATLSAPTLLLPSIQVNIRAGRFPKAQQNGVHYLLLPVHAR
EEEECCCCHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCEEEEEEEECC
PGAEAGLS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]