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The map label for this gene is atpA [H]

Identifier: 86747393

GI number: 86747393

Start: 300452

End: 301984

Strand: Reverse

Name: atpA [H]

Synonym: RPB_0267

Alternate gene names: 86747393

Gene position: 301984-300452 (Counterclockwise)

Preceding gene: 86747394

Following gene: 86747392

Centisome position: 5.66

GC content: 65.36

Gene sequence:

>1533_bases
ATGGACATCCGCGCCGCGGAAATTTCCGCGATCCTCAAGGACCAGATCAAGAACTTCGGTCAGGAAGCCGAAGTCACCGA
AGTCGGACAGGTGCTGTCCGTCGGCGACGGCATTGCCCGCGTCTACGGTCTGGACAACGTCCAGGCCGGTGAAATGGTCG
AGTTCGAGAACGGCACGCGCGGCATGGCGCTGAACCTCGAAACCGACAATGTCGGCGTCGTGATCTTCGGCGCCGACCGC
GAGATCAAGGAAGGCCAGACCGTCAAGCGCACCCGCTCGATCGTCGACACGCCGGTCGGCAAGGGCCTGCTCGGCCGCGT
CGTCGACGCGCTCGGCAATCCGATCGACGGCAAGGGTCCGATCCAGGCGACCGAGCGCAAGCGCGTCGACGTCAAGGCGC
CCGGCATCATTCCGCGCAAGTCGGTGAACGAGCCGATGGCGACCGGCCTCAAGGCGATCGACGCCCTGATCCCGGTCGGC
CGCGGCCAGCGCGAGCTGATCATCGGCGACCGTCAGACCGGCAAGACCGCGATCGCGCTCGACACCATCCTGAACCAGAA
GCCGCTCAACGTCGAAGGCGCGCCGGAAGGCCAGAAGCTGTACTGCGTCTACGTCGCGGTCGGCCAGAAGCGCTCGACTG
TCGCGCAGTTCGTCAAGGTGCTGGAAGAGCAGGGCGCGCTCGAATATTCGATCGTCGTCGCCGCCACCGCCTCCGATCCG
GCACCGATGCAGTACATCGCGCCGTTCACCGGCTGCACCATGGGCGAATACTTCCGCGACAACGGCATGCACGCCGTCAT
CATCTATGACGATCTGTCCAAGCAGGCCGTCGCCTATCGCCAGATGTCGCTGTTGCTGCGCCGCCCGCCGGGCCGCGAAG
CCTATCCGGGCGACGTGTTCTATCTGCACTCCCGCCTGCTCGAGCGCGCCGCCAAGCTGAACGACGATCACGGCGCCGGC
TCGCTGACCGCGCTGCCGGTGATCGAAACCCAGGCCAACGACGTCTCGGCCTACATTCCGACCAACGTGATTTCGATCAC
CGACGGCCAGATCTTTCTGGAAACCGATCTGTTCTTCCAGGGCATCCGCCCGGCGGTGAACGTCGGTCTGTCGGTGTCGC
GCGTCGGATCGTCGGCGCAGACCAAGGCGATGAAGAAGGTCGCCGGCAAGATCAAGGGCGAGCTCGCGCAGTACCGCGAA
ATGGCGGCGTTCGCGCAGTTCGGCTCCGATCTCGACGCCTCGACCCAGCGCCTGCTGAACCGCGGTGCCCGCCTGACCGA
ACTCCTGAAGCAGCCGCAGTTCTCGCCGCTGAAGATGGAAGAGCAGGTCGTGGTGATCTACGCCGGCGTCAACGGCTATC
TCGATGCGCTGCCGGTCGCCAAGGTGCGCGCCTTCGAGGACGGCCTGCTGTCGCTCCTGCGCGGCAAGGAAGTCGGCATT
CTCGATGCGATCCGCACCAGCCGCGATCTCTCCGACGACACCGCCGCCAAGCTCAAGGCGGTCGTCGAGAGCTACGCCAA
GACGTTCGCGTAA

Upstream 100 bases:

>100_bases
TCATCGGCGGGCTTGTCGTCAAGCTCGGCAGCCGCATGGTCGACAGTTCGATCCGCACCAAACTCAATTCGATCAAGCAC
GCGATGAAAGAGGCAGGCTG

Downstream 100 bases:

>100_bases
CGTTCATGGCCGGCGACACGCCGGCCATTCACGCTTCTGGCGTGAAGCATTTCAAGTCGTGGATGCCCGGGACGAGCCCG
GGCATGACGAGTGTGAGGGT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MDIRAAEISAILKDQIKNFGQEAEVTEVGQVLSVGDGIARVYGLDNVQAGEMVEFENGTRGMALNLETDNVGVVIFGADR
EIKEGQTVKRTRSIVDTPVGKGLLGRVVDALGNPIDGKGPIQATERKRVDVKAPGIIPRKSVNEPMATGLKAIDALIPVG
RGQRELIIGDRQTGKTAIALDTILNQKPLNVEGAPEGQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDP
APMQYIAPFTGCTMGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDHGAG
SLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYRE
MAAFAQFGSDLDASTQRLLNRGARLTELLKQPQFSPLKMEEQVVVIYAGVNGYLDALPVAKVRAFEDGLLSLLRGKEVGI
LDAIRTSRDLSDDTAAKLKAVVESYAKTFA

Sequences:

>Translated_510_residues
MDIRAAEISAILKDQIKNFGQEAEVTEVGQVLSVGDGIARVYGLDNVQAGEMVEFENGTRGMALNLETDNVGVVIFGADR
EIKEGQTVKRTRSIVDTPVGKGLLGRVVDALGNPIDGKGPIQATERKRVDVKAPGIIPRKSVNEPMATGLKAIDALIPVG
RGQRELIIGDRQTGKTAIALDTILNQKPLNVEGAPEGQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDP
APMQYIAPFTGCTMGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDHGAG
SLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYRE
MAAFAQFGSDLDASTQRLLNRGARLTELLKQPQFSPLKMEEQVVVIYAGVNGYLDALPVAKVRAFEDGLLSLLRGKEVGI
LDAIRTSRDLSDDTAAKLKAVVESYAKTFA
>Mature_510_residues
MDIRAAEISAILKDQIKNFGQEAEVTEVGQVLSVGDGIARVYGLDNVQAGEMVEFENGTRGMALNLETDNVGVVIFGADR
EIKEGQTVKRTRSIVDTPVGKGLLGRVVDALGNPIDGKGPIQATERKRVDVKAPGIIPRKSVNEPMATGLKAIDALIPVG
RGQRELIIGDRQTGKTAIALDTILNQKPLNVEGAPEGQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDP
APMQYIAPFTGCTMGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDHGAG
SLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYRE
MAAFAQFGSDLDASTQRLLNRGARLTELLKQPQFSPLKMEEQVVVIYAGVNGYLDALPVAKVRAFEDGLLSLLRGKEVGI
LDAIRTSRDLSDDTAAKLKAVVESYAKTFA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=70.2380952380952, Blast_Score=727, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=70.2380952380952, Blast_Score=727, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=358, Percent_Identity=28.2122905027933, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI19913426, Length=317, Percent_Identity=28.7066246056782, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI32189394, Length=358, Percent_Identity=25.4189944134078, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI19913424, Length=251, Percent_Identity=26.6932270916335, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1790172, Length=519, Percent_Identity=53.3718689788054, Blast_Score=560, Evalue=1e-161,
Organism=Escherichia coli, GI1790170, Length=406, Percent_Identity=25.1231527093596, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788251, Length=388, Percent_Identity=27.5773195876289, Blast_Score=102, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=504, Percent_Identity=69.8412698412698, Blast_Score=720, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=504, Percent_Identity=69.8412698412698, Blast_Score=719, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=504, Percent_Identity=64.8809523809524, Blast_Score=656, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570191, Length=331, Percent_Identity=27.4924471299094, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=304, Percent_Identity=28.9473684210526, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=394, Percent_Identity=24.8730964467005, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71988068, Length=76, Percent_Identity=56.578947368421, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17565854, Length=263, Percent_Identity=25.8555133079848, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=503, Percent_Identity=69.1848906560636, Blast_Score=721, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=350, Percent_Identity=30.5714285714286, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=418, Percent_Identity=25.3588516746411, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24658560, Length=506, Percent_Identity=69.5652173913043, Blast_Score=720, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=312, Percent_Identity=28.8461538461538, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646341, Length=312, Percent_Identity=28.8461538461538, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17136796, Length=312, Percent_Identity=28.8461538461538, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24638766, Length=381, Percent_Identity=24.9343832020997, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28574560, Length=424, Percent_Identity=25, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24583992, Length=251, Percent_Identity=25.8964143426295, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583988, Length=251, Percent_Identity=25.8964143426295, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583986, Length=251, Percent_Identity=25.8964143426295, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583984, Length=251, Percent_Identity=25.8964143426295, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129479, Length=251, Percent_Identity=27.8884462151394, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55068; Mature: 55068

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRAAEISAILKDQIKNFGQEAEVTEVGQVLSVGDGIARVYGLDNVQAGEMVEFENGTR
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEECCCCC
GMALNLETDNVGVVIFGADREIKEGQTVKRTRSIVDTPVGKGLLGRVVDALGNPIDGKGP
CEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
IQATERKRVDVKAPGIIPRKSVNEPMATGLKAIDALIPVGRGQRELIIGDRQTGKTAIAL
CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTILNQKPLNVEGAPEGQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDP
HHHHCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCC
APMQYIAPFTGCTMGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVF
CCCCEECCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
YLHSRLLERAAKLNDDHGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQ
HHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEHHHHH
GIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDASTQRLLN
CCCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RGARLTELLKQPQFSPLKMEEQVVVIYAGVNGYLDALPVAKVRAFEDGLLSLLRGKEVGI
CCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCH
LDAIRTSRDLSDDTAAKLKAVVESYAKTFA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIRAAEISAILKDQIKNFGQEAEVTEVGQVLSVGDGIARVYGLDNVQAGEMVEFENGTR
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEECCCCC
GMALNLETDNVGVVIFGADREIKEGQTVKRTRSIVDTPVGKGLLGRVVDALGNPIDGKGP
CEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
IQATERKRVDVKAPGIIPRKSVNEPMATGLKAIDALIPVGRGQRELIIGDRQTGKTAIAL
CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTILNQKPLNVEGAPEGQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDP
HHHHCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCC
APMQYIAPFTGCTMGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVF
CCCCEECCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
YLHSRLLERAAKLNDDHGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQ
HHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEHHHHH
GIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDASTQRLLN
CCCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RGARLTELLKQPQFSPLKMEEQVVVIYAGVNGYLDALPVAKVRAFEDGLLSLLRGKEVGI
CCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCH
LDAIRTSRDLSDDTAAKLKAVVESYAKTFA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA