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The map label for this gene is pyc [H]

Identifier: 86747354

GI number: 86747354

Start: 257855

End: 261163

Strand: Reverse

Name: pyc [H]

Synonym: RPB_0228

Alternate gene names: 86747354

Gene position: 261163-257855 (Counterclockwise)

Preceding gene: 86747355

Following gene: 86747353

Centisome position: 4.9

GC content: 67.72

Gene sequence:

>3309_bases
ATGCCGTTTCGCAAGCTGCTGATCGCCAACCGCGGCGAGATCGCGATCCGCATCGCGCGGGCCGCGGCCGACGCCGGGCT
CGCCACCGTCGCGATCCATCCCGCCGACGATGCGGCGTCGCTGCATGTGCGGATCGCCGACGAGGCGCGGGAGATTCCCG
GGCGCGGCGCGCGGGCTTATCTGGATATCGAGGGCGTGATCGCGGCCGCCAAGGCGGCGCATTGCGACGCGCTGCATCCC
GGCTACGGCTTCCTCAGCGAGAACCCCGATCTGGCGCGGCGCTGCGCCGAGGAAGGTATCCGGTTCATCGGTCCGTCGCC
AGAAGCCTTGCGGCTATTCGGTGACAAAGTTGCGGCGAAGGAATTGGCCAAGAAATCCGGCGTGCCGATCATCGACGGCA
CCCAGGGTCCTTCGACTCTCGATGAGGTGAAGGCGTTCTTCGGCTCGCTCGGCGATCATGCCGCGGTAATGATCAAGGCG
ATGGCCGGCGGCGGCGGCCGCGGTATGCGTGTGGTCGAGCGCGCCGAGGATCTCGACGAGGCCTATGCGCGCTGCCAGTC
CGAGGCGAAGGCGGCGTTCGGCAGCGACGGCGTCTATGCCGAGCGGCTGATCCGCAATGCGCGGCATATCGAGGTGCAGA
TCATCGGCGATCGTCACGGCGGCATCAGTCAGTTGTGGGAGCGCGAATGCACGATCCAGCGCCGCAACCAGAAGCTGGTC
GAGATCGCGCCGAGCCCGTCGCTGAGTGATAGCTTGCGCGGCCGCATTCTCGAAGCCGCCAAGACGCTGGCTGGTGCGGC
GAACTACGACAGTCTCGGTACGTTCGAATTCCTGGTCGACGGCGAAGCCGGCGAGGGCGACGGCGCGTTCGCGTTCATCG
AGGCCAATCCGCGGCTGCAGGTCGAGCACACCGTGACCGAGGAAGTCCTTGCGATCGATCTGGTGCGATCGCAGATCGCG
GTGGCCGGCGGCGCGACGCTGGAATCGCTCGGGCTCGATCAGGCCGCGGTGCCGCGCCCGCGCGGCTTCGCGATGCAGCT
CCGTATCAACATGGAGACGATGGACGCGAGCGGCGCGACCCATCCGACCGGCGGCACGCTTTCGATCTTCGAGCCGCCGT
CGGGTCCGGGCGTGCGCGTCGATACGTTCGGCTATGCCGGCTACAGGACCAGCGCGGCGTTCGACTCGCTGCTGGCAAAA
GTGATCGTGCACACGCCGTCGCAATGGCCGGATGTCGTCGCCAAGGCGGCGCGCAGCCTGCGTGAGTTCCGCATCGACGG
CGTCGCCACCAACATCCCGTTCATCCAGGCGATCCTGGCGCATCCGGACTTCAAGGCCAACAAGGTCAGCACCAGCTTCA
TCGACCGCAACGTCGCCGAGCTGGTCGGCGCCGCGGACAAGCTCGCCGCGCCACTGATCGCGTTGCCGGGTGGTGATGCG
CAGCACGGTGGCGCGAAGGCCGCGGTCGAAGCCGCGCCCGAAGGCGCGGTCGTGATCGCCGCGCCGCTGCAGGGCACCGT
GGTGGCGATCACGGTCGCGGAAGGCGACGTGGTGCGGCCGGGGCAGCAGCTCGCGGTGATCGAATCGATGAAGATGGAGC
ATCTCGTCGCCGCCGAGCAGGGCGGCCGGATTCGCCGCATCGTCACCGCCGACGGCGTGACGCTGATGCAGGGCGAGGCG
ATCCTCTATCTCGAGCCGCAGGACGTCGAGGGCGATCTGGCCGTCAAGGAGGCCGAAGTCGATCTCGACCATATCCGTCC
CGACCTCGCCGAGATGCTGGCGCGGCAGGGCAATACGCTCGACGAGAACCGGCCCGATTCGGTCGCGCGCCGGCGCAAGA
CCAATCAGCGCACCGCGCGCGAGAACATCGCCCAGCTGGTCGACGACGGCTCCTTCATGGAATACGGCAGCCTCGCGATC
GCAGGCCAGCGTCGCCGCCGCGCGCTCGATGACCTGATCAAGAACACCCCGGCCGACGGTCTCGTCACCGGCGTCGCCAC
CGTCAACGCCGCGCAATTCGGCGAGCACGATGCGCGCTGCATGGTGATCGCCTACGACTACACGGTTCTGGCCGGCACCC
AGGGCCATATGAACCACAAGAAGATCGACCGGATGCTGACGCTGGTCGAGCAATGGAAGATGCCGCTGGTGTTCTACGCC
GAAGGCGGCGGCGGCCGTCCCGGCGACACCGACCGGCTCGGCCTCACCGGCCTCGACGGGCCGTCCTTCGTGCAGTTCGC
GCGATTGTCCGGCCTGGTGCCGGTGATCGGCGTGGTTTCCGGCTATTGCTTCGCCGGCAATGCGGCGATGCTCGGCTGCT
GCGACGTGATCATCGCGACGCAAAACGCCTCGATCGGCATGGGCGGCCCGGCGATGATCGAGGGCGGCGGCCTCGGCGTG
TATCACCCGGCCGAAGTCGGCCCGGTGTCGTTCCAGTCGCCGAACGGCGTGGTCGATATTCTGGTCGAGGACGAGGAAGA
GGCGACGCGGGTCGCGCAGAAATATCTGTCCTACTTCCAGGGCCCGGTGAAGGACTGGCGCGCGGCGGACCAGCGGCTGC
TGCGCCGCGCGATTCCCGAAAATCGTCTGCGGGTCTACGACGTCCGCCACGTCATCGATCTGATCGCGGACGAAGATTCG
GTGCTGGAAATCCGCCGCGACTTCGGCGTCGGCATGGTCACCGCCTTCATCCGCATCGAGGGCAAGCCGTTCGGCCTGAT
CGCCAACAATCCGAAGCATCTCGGCGGCGCGATCGACGCGGCGGCCGGCGACAAGGCGGCGCGTTTCCTGCAGCTGTGCG
ACGCCTTCGATATTCCGATCGTGTCGCTGTGCGATACGCCCGGCTTCATGGTCGGCCCCGAAGCCGAGAAGACCGCGATC
GTACGGCACGTCGCGCGGATGTTCGTCACCGGCGCCAGCCTGACGGTGCCGCTGTTCGGCATCGTGCTGCGCAAGGGCTA
CGGGCTCGGCGCGCAGTCGATGATCGGCGGCGGCTTCCACGCCTCGTTTTTCACCGCGGCGTGGCCGACCGGCGAATTCG
GCGGCATGGGGCTGGAGGGCTATGTCCGCCTCGGCTTCCGCAAGGAGATGGAAGCGATCGCCGACCCGGTCGAGCGCGAG
ACCTACTACAAGAACAAGGTCGCCGAGATGTACGCCAACGGCAAGGCGGTCTCGATCGCGTCGGTGTGTGAGATCGACAA
CGTGATCGATCCCGCCGAGACGCGGCGCTGGATCATGGCCGGGCTGCGCTCGGTACCGACGCCACCGCAGCGCGAGGGGC
GCAAGCGGCCCTGCATCGACGCCTGGTAG

Upstream 100 bases:

>100_bases
GGTGAAGAAGCAGGAGCTGAACGCCAGCGCGCCGCTCTGACATTGCCGCCGCAGCGACGCGGCTCCGCCACCAAGAATTT
GATTATATGAGGACATTCGA

Downstream 100 bases:

>100_bases
TTCGAAGACCTGTTGTTGAGACGGAGCAAACGATGACACGAGCCGCTTTCGAGACGCCGATCGAGGACACCGGCGATGCG
CTGGCCGGGCCGTGGCGGCA

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1102; Mature: 1101

Protein sequence:

>1102_residues
MPFRKLLIANRGEIAIRIARAAADAGLATVAIHPADDAASLHVRIADEAREIPGRGARAYLDIEGVIAAAKAAHCDALHP
GYGFLSENPDLARRCAEEGIRFIGPSPEALRLFGDKVAAKELAKKSGVPIIDGTQGPSTLDEVKAFFGSLGDHAAVMIKA
MAGGGGRGMRVVERAEDLDEAYARCQSEAKAAFGSDGVYAERLIRNARHIEVQIIGDRHGGISQLWERECTIQRRNQKLV
EIAPSPSLSDSLRGRILEAAKTLAGAANYDSLGTFEFLVDGEAGEGDGAFAFIEANPRLQVEHTVTEEVLAIDLVRSQIA
VAGGATLESLGLDQAAVPRPRGFAMQLRINMETMDASGATHPTGGTLSIFEPPSGPGVRVDTFGYAGYRTSAAFDSLLAK
VIVHTPSQWPDVVAKAARSLREFRIDGVATNIPFIQAILAHPDFKANKVSTSFIDRNVAELVGAADKLAAPLIALPGGDA
QHGGAKAAVEAAPEGAVVIAAPLQGTVVAITVAEGDVVRPGQQLAVIESMKMEHLVAAEQGGRIRRIVTADGVTLMQGEA
ILYLEPQDVEGDLAVKEAEVDLDHIRPDLAEMLARQGNTLDENRPDSVARRRKTNQRTARENIAQLVDDGSFMEYGSLAI
AGQRRRRALDDLIKNTPADGLVTGVATVNAAQFGEHDARCMVIAYDYTVLAGTQGHMNHKKIDRMLTLVEQWKMPLVFYA
EGGGGRPGDTDRLGLTGLDGPSFVQFARLSGLVPVIGVVSGYCFAGNAAMLGCCDVIIATQNASIGMGGPAMIEGGGLGV
YHPAEVGPVSFQSPNGVVDILVEDEEEATRVAQKYLSYFQGPVKDWRAADQRLLRRAIPENRLRVYDVRHVIDLIADEDS
VLEIRRDFGVGMVTAFIRIEGKPFGLIANNPKHLGGAIDAAAGDKAARFLQLCDAFDIPIVSLCDTPGFMVGPEAEKTAI
VRHVARMFVTGASLTVPLFGIVLRKGYGLGAQSMIGGGFHASFFTAAWPTGEFGGMGLEGYVRLGFRKEMEAIADPVERE
TYYKNKVAEMYANGKAVSIASVCEIDNVIDPAETRRWIMAGLRSVPTPPQREGRKRPCIDAW

Sequences:

>Translated_1102_residues
MPFRKLLIANRGEIAIRIARAAADAGLATVAIHPADDAASLHVRIADEAREIPGRGARAYLDIEGVIAAAKAAHCDALHP
GYGFLSENPDLARRCAEEGIRFIGPSPEALRLFGDKVAAKELAKKSGVPIIDGTQGPSTLDEVKAFFGSLGDHAAVMIKA
MAGGGGRGMRVVERAEDLDEAYARCQSEAKAAFGSDGVYAERLIRNARHIEVQIIGDRHGGISQLWERECTIQRRNQKLV
EIAPSPSLSDSLRGRILEAAKTLAGAANYDSLGTFEFLVDGEAGEGDGAFAFIEANPRLQVEHTVTEEVLAIDLVRSQIA
VAGGATLESLGLDQAAVPRPRGFAMQLRINMETMDASGATHPTGGTLSIFEPPSGPGVRVDTFGYAGYRTSAAFDSLLAK
VIVHTPSQWPDVVAKAARSLREFRIDGVATNIPFIQAILAHPDFKANKVSTSFIDRNVAELVGAADKLAAPLIALPGGDA
QHGGAKAAVEAAPEGAVVIAAPLQGTVVAITVAEGDVVRPGQQLAVIESMKMEHLVAAEQGGRIRRIVTADGVTLMQGEA
ILYLEPQDVEGDLAVKEAEVDLDHIRPDLAEMLARQGNTLDENRPDSVARRRKTNQRTARENIAQLVDDGSFMEYGSLAI
AGQRRRRALDDLIKNTPADGLVTGVATVNAAQFGEHDARCMVIAYDYTVLAGTQGHMNHKKIDRMLTLVEQWKMPLVFYA
EGGGGRPGDTDRLGLTGLDGPSFVQFARLSGLVPVIGVVSGYCFAGNAAMLGCCDVIIATQNASIGMGGPAMIEGGGLGV
YHPAEVGPVSFQSPNGVVDILVEDEEEATRVAQKYLSYFQGPVKDWRAADQRLLRRAIPENRLRVYDVRHVIDLIADEDS
VLEIRRDFGVGMVTAFIRIEGKPFGLIANNPKHLGGAIDAAAGDKAARFLQLCDAFDIPIVSLCDTPGFMVGPEAEKTAI
VRHVARMFVTGASLTVPLFGIVLRKGYGLGAQSMIGGGFHASFFTAAWPTGEFGGMGLEGYVRLGFRKEMEAIADPVERE
TYYKNKVAEMYANGKAVSIASVCEIDNVIDPAETRRWIMAGLRSVPTPPQREGRKRPCIDAW
>Mature_1101_residues
PFRKLLIANRGEIAIRIARAAADAGLATVAIHPADDAASLHVRIADEAREIPGRGARAYLDIEGVIAAAKAAHCDALHPG
YGFLSENPDLARRCAEEGIRFIGPSPEALRLFGDKVAAKELAKKSGVPIIDGTQGPSTLDEVKAFFGSLGDHAAVMIKAM
AGGGGRGMRVVERAEDLDEAYARCQSEAKAAFGSDGVYAERLIRNARHIEVQIIGDRHGGISQLWERECTIQRRNQKLVE
IAPSPSLSDSLRGRILEAAKTLAGAANYDSLGTFEFLVDGEAGEGDGAFAFIEANPRLQVEHTVTEEVLAIDLVRSQIAV
AGGATLESLGLDQAAVPRPRGFAMQLRINMETMDASGATHPTGGTLSIFEPPSGPGVRVDTFGYAGYRTSAAFDSLLAKV
IVHTPSQWPDVVAKAARSLREFRIDGVATNIPFIQAILAHPDFKANKVSTSFIDRNVAELVGAADKLAAPLIALPGGDAQ
HGGAKAAVEAAPEGAVVIAAPLQGTVVAITVAEGDVVRPGQQLAVIESMKMEHLVAAEQGGRIRRIVTADGVTLMQGEAI
LYLEPQDVEGDLAVKEAEVDLDHIRPDLAEMLARQGNTLDENRPDSVARRRKTNQRTARENIAQLVDDGSFMEYGSLAIA
GQRRRRALDDLIKNTPADGLVTGVATVNAAQFGEHDARCMVIAYDYTVLAGTQGHMNHKKIDRMLTLVEQWKMPLVFYAE
GGGGRPGDTDRLGLTGLDGPSFVQFARLSGLVPVIGVVSGYCFAGNAAMLGCCDVIIATQNASIGMGGPAMIEGGGLGVY
HPAEVGPVSFQSPNGVVDILVEDEEEATRVAQKYLSYFQGPVKDWRAADQRLLRRAIPENRLRVYDVRHVIDLIADEDSV
LEIRRDFGVGMVTAFIRIEGKPFGLIANNPKHLGGAIDAAAGDKAARFLQLCDAFDIPIVSLCDTPGFMVGPEAEKTAIV
RHVARMFVTGASLTVPLFGIVLRKGYGLGAQSMIGGGFHASFFTAAWPTGEFGGMGLEGYVRLGFRKEMEAIADPVERET
YYKNKVAEMYANGKAVSIASVCEIDNVIDPAETRRWIMAGLRSVPTPPQREGRKRPCIDAW

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=461, Percent_Identity=47.0715835140998, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI106049295, Length=461, Percent_Identity=47.0715835140998, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI106049292, Length=461, Percent_Identity=47.0715835140998, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI116805327, Length=465, Percent_Identity=39.3548387096774, Blast_Score=320, Evalue=5e-87,
Organism=Homo sapiens, GI65506442, Length=455, Percent_Identity=41.3186813186813, Blast_Score=289, Evalue=1e-77,
Organism=Homo sapiens, GI295821183, Length=455, Percent_Identity=41.3186813186813, Blast_Score=289, Evalue=1e-77,
Organism=Homo sapiens, GI189095269, Length=455, Percent_Identity=41.3186813186813, Blast_Score=288, Evalue=1e-77,
Organism=Homo sapiens, GI38679977, Length=521, Percent_Identity=29.1746641074856, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI38679967, Length=521, Percent_Identity=29.1746641074856, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI38679971, Length=521, Percent_Identity=29.1746641074856, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI38679974, Length=521, Percent_Identity=29.1746641074856, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI38679960, Length=521, Percent_Identity=29.1746641074856, Blast_Score=191, Evalue=4e-48,
Organism=Homo sapiens, GI134142062, Length=521, Percent_Identity=28.9827255278311, Blast_Score=173, Evalue=8e-43,
Organism=Homo sapiens, GI119943100, Length=507, Percent_Identity=26.232741617357, Blast_Score=157, Evalue=8e-38,
Organism=Homo sapiens, GI295821216, Length=520, Percent_Identity=25.9615384615385, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI11545863, Length=352, Percent_Identity=28.6931818181818, Blast_Score=114, Evalue=4e-25,
Organism=Escherichia coli, GI1789654, Length=458, Percent_Identity=39.7379912663755, Blast_Score=290, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI17562816, Length=460, Percent_Identity=44.7826086956522, Blast_Score=354, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI71987519, Length=471, Percent_Identity=39.0658174097665, Blast_Score=308, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI17567343, Length=456, Percent_Identity=39.2543859649123, Blast_Score=273, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI133931226, Length=524, Percent_Identity=27.4809160305344, Blast_Score=173, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI25147359, Length=497, Percent_Identity=26.7605633802817, Blast_Score=168, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI25147362, Length=497, Percent_Identity=26.7605633802817, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71997168, Length=531, Percent_Identity=25.9887005649718, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71997163, Length=531, Percent_Identity=25.9887005649718, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17552936, Length=506, Percent_Identity=26.4822134387352, Blast_Score=137, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6319695, Length=457, Percent_Identity=44.4201312910284, Blast_Score=328, Evalue=2e-90,
Organism=Saccharomyces cerevisiae, GI6321376, Length=457, Percent_Identity=44.4201312910284, Blast_Score=315, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6319685, Length=454, Percent_Identity=37.6651982378855, Blast_Score=291, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6323863, Length=488, Percent_Identity=28.2786885245902, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324343, Length=524, Percent_Identity=28.6259541984733, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI281363050, Length=461, Percent_Identity=47.5054229934924, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652224, Length=461, Percent_Identity=47.5054229934924, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652222, Length=461, Percent_Identity=47.5054229934924, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652220, Length=461, Percent_Identity=47.5054229934924, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652218, Length=461, Percent_Identity=47.5054229934924, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652212, Length=461, Percent_Identity=47.5054229934924, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652210, Length=461, Percent_Identity=47.5054229934924, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652214, Length=461, Percent_Identity=47.5054229934924, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI19921944, Length=461, Percent_Identity=47.5054229934924, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652216, Length=461, Percent_Identity=47.5054229934924, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24651757, Length=478, Percent_Identity=39.3305439330544, Blast_Score=308, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24651759, Length=439, Percent_Identity=38.496583143508, Blast_Score=274, Evalue=3e-73,
Organism=Drosophila melanogaster, GI161076407, Length=520, Percent_Identity=27.6923076923077, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24586460, Length=520, Percent_Identity=27.6923076923077, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI161076409, Length=520, Percent_Identity=27.6923076923077, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24586458, Length=520, Percent_Identity=27.6923076923077, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24586065, Length=517, Percent_Identity=26.1121856866538, Blast_Score=130, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 117805; Mature: 117674

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFRKLLIANRGEIAIRIARAAADAGLATVAIHPADDAASLHVRIADEAREIPGRGARAY
CCCHHEEEECCCCEEEEEEEHHCCCCEEEEEEECCCCCCEEEEEECCHHHCCCCCCCEEE
LDIEGVIAAAKAAHCDALHPGYGFLSENPDLARRCAEEGIRFIGPSPEALRLFGDKVAAK
EEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHH
ELAKKSGVPIIDGTQGPSTLDEVKAFFGSLGDHAAVMIKAMAGGGGRGMRVVERAEDLDE
HHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
AYARCQSEAKAAFGSDGVYAERLIRNARHIEVQIIGDRHGGISQLWERECTIQRRNQKLV
HHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEE
EIAPSPSLSDSLRGRILEAAKTLAGAANYDSLGTFEFLVDGEAGEGDGAFAFIEANPRLQ
EECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCEE
VEHTVTEEVLAIDLVRSQIAVAGGATLESLGLDQAAVPRPRGFAMQLRINMETMDASGAT
EEHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEEEEEEEEECCCCCC
HPTGGTLSIFEPPSGPGVRVDTFGYAGYRTSAAFDSLLAKVIVHTPSQWPDVVAKAARSL
CCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
REFRIDGVATNIPFIQAILAHPDFKANKVSTSFIDRNVAELVGAADKLAAPLIALPGGDA
HHHHHCCEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCEEECCCCCC
QHGGAKAAVEAAPEGAVVIAAPLQGTVVAITVAEGDVVRPGQQLAVIESMKMEHLVAAEQ
CCCCCCHHHCCCCCCCEEEEECCCCEEEEEEEECCCEECCCHHHHHHHHHHHHHHHHHCC
GGRIRRIVTADGVTLMQGEAILYLEPQDVEGDLAVKEAEVDLDHIRPDLAEMLARQGNTL
CCCEEEEEEECCEEEEECCEEEEECCCCCCCCEEEEECCCCHHHCCHHHHHHHHHCCCCC
DENRPDSVARRRKTNQRTARENIAQLVDDGSFMEYGSLAIAGQRRRRALDDLIKNTPADG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCEEEECHHHHHHHHHHHHCCCCCC
LVTGVATVNAAQFGEHDARCMVIAYDYTVLAGTQGHMNHKKIDRMLTLVEQWKMPLVFYA
EEEHHHHCCHHHCCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEE
EGGGGRPGDTDRLGLTGLDGPSFVQFARLSGLVPVIGVVSGYCFAGNAAMLGCCDVIIAT
ECCCCCCCCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHCCCEECCCCHHEEEEEEEEEE
QNASIGMGGPAMIEGGGLGVYHPAEVGPVSFQSPNGVVDILVEDEEEATRVAQKYLSYFQ
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHC
GPVKDWRAADQRLLRRAIPENRLRVYDVRHVIDLIADEDSVLEIRRDFGVGMVTAFIRIE
CCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEEC
GKPFGLIANNPKHLGGAIDAAAGDKAARFLQLCDAFDIPIVSLCDTPGFMVGPEAEKTAI
CCEEEEEECCCHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEECCCHHHHHH
VRHVARMFVTGASLTVPLFGIVLRKGYGLGAQSMIGGGFHASFFTAAWPTGEFGGMGLEG
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHEEECCCCCCCCCCCCH
YVRLGFRKEMEAIADPVERETYYKNKVAEMYANGKAVSIASVCEIDNVIDPAETRRWIMA
HEEECHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHH
GLRSVPTPPQREGRKRPCIDAW
HHHCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure 
PFRKLLIANRGEIAIRIARAAADAGLATVAIHPADDAASLHVRIADEAREIPGRGARAY
CCHHEEEECCCCEEEEEEEHHCCCCEEEEEEECCCCCCEEEEEECCHHHCCCCCCCEEE
LDIEGVIAAAKAAHCDALHPGYGFLSENPDLARRCAEEGIRFIGPSPEALRLFGDKVAAK
EEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHH
ELAKKSGVPIIDGTQGPSTLDEVKAFFGSLGDHAAVMIKAMAGGGGRGMRVVERAEDLDE
HHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
AYARCQSEAKAAFGSDGVYAERLIRNARHIEVQIIGDRHGGISQLWERECTIQRRNQKLV
HHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEE
EIAPSPSLSDSLRGRILEAAKTLAGAANYDSLGTFEFLVDGEAGEGDGAFAFIEANPRLQ
EECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCEE
VEHTVTEEVLAIDLVRSQIAVAGGATLESLGLDQAAVPRPRGFAMQLRINMETMDASGAT
EEHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEEEEEEEEECCCCCC
HPTGGTLSIFEPPSGPGVRVDTFGYAGYRTSAAFDSLLAKVIVHTPSQWPDVVAKAARSL
CCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
REFRIDGVATNIPFIQAILAHPDFKANKVSTSFIDRNVAELVGAADKLAAPLIALPGGDA
HHHHHCCEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCEEECCCCCC
QHGGAKAAVEAAPEGAVVIAAPLQGTVVAITVAEGDVVRPGQQLAVIESMKMEHLVAAEQ
CCCCCCHHHCCCCCCCEEEEECCCCEEEEEEEECCCEECCCHHHHHHHHHHHHHHHHHCC
GGRIRRIVTADGVTLMQGEAILYLEPQDVEGDLAVKEAEVDLDHIRPDLAEMLARQGNTL
CCCEEEEEEECCEEEEECCEEEEECCCCCCCCEEEEECCCCHHHCCHHHHHHHHHCCCCC
DENRPDSVARRRKTNQRTARENIAQLVDDGSFMEYGSLAIAGQRRRRALDDLIKNTPADG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCEEEECHHHHHHHHHHHHCCCCCC
LVTGVATVNAAQFGEHDARCMVIAYDYTVLAGTQGHMNHKKIDRMLTLVEQWKMPLVFYA
EEEHHHHCCHHHCCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEE
EGGGGRPGDTDRLGLTGLDGPSFVQFARLSGLVPVIGVVSGYCFAGNAAMLGCCDVIIAT
ECCCCCCCCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHCCCEECCCCHHEEEEEEEEEE
QNASIGMGGPAMIEGGGLGVYHPAEVGPVSFQSPNGVVDILVEDEEEATRVAQKYLSYFQ
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHC
GPVKDWRAADQRLLRRAIPENRLRVYDVRHVIDLIADEDSVLEIRRDFGVGMVTAFIRIE
CCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEEC
GKPFGLIANNPKHLGGAIDAAAGDKAARFLQLCDAFDIPIVSLCDTPGFMVGPEAEKTAI
CCEEEEEECCCHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEECCCHHHHHH
VRHVARMFVTGASLTVPLFGIVLRKGYGLGAQSMIGGGFHASFFTAAWPTGEFGGMGLEG
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHEEECCCCCCCCCCCCH
YVRLGFRKEMEAIADPVERETYYKNKVAEMYANGKAVSIASVCEIDNVIDPAETRRWIMA
HEEECHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHH
GLRSVPTPPQREGRKRPCIDAW
HHHCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]