| Definition | Rhodopseudomonas palustris HaA2, complete genome. |
|---|---|
| Accession | NC_007778 |
| Length | 5,331,656 |
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The map label for this gene is sdh [H]
Identifier: 86747240
GI number: 86747240
Start: 123314
End: 124093
Strand: Reverse
Name: sdh [H]
Synonym: RPB_0113
Alternate gene names: 86747240
Gene position: 124093-123314 (Counterclockwise)
Preceding gene: 86747241
Following gene: 86747239
Centisome position: 2.33
GC content: 66.67
Gene sequence:
>780_bases GTGACTGAACGCGTGACGTTGATAACGGGGGCATCGGCTGGCATCGGCACGGAGCTGGCGCGCATTTTCGCGGCAAATGC TCACAGAGTGGCCTTGGTGGCGCGACGCGCCGACCGGCTCGAGGCGCTGGCTGCGGAAATCACGGCCAAGGGCGGCAAGG AACCGATCATCATCGTCTGCGATCTGGCGAAGCCCGAGGCGGTCGACGAGATCGTGGCCCGGCTGACTGCGGCCGGGGTC GAGGTCGAGTACCTCGTCAACAATGCCGGCTATGGCCTGTTCGGCCGCGCCGCGGAGATCGACCGCGAGGATCAGCTCGG CATCATCGACGTCAATATCCGCGCGCTGACCGACCTGTCGCTGCGCTTCGCCGACAGCGTCGCGAAACTGCGCGGCGGCA TCCTCAACGTCGCGTCGATCGCCAGCTTCCTGCCGGGGCCCGGCATGGCGGTGTACTATGCCTCCAAGGCCTATGTGCTG TCGCTGAGCGAGGCGCTGCATCAGGAACTGGGCAAGAAGGGCGTCAGGGTCACGGCGATCTGTCCTGGGCCGGTGTCGAC CGAATTCCAGTCGCGCGCGGGCTTCGAGCCCGGCTTCGATTCGGCGGTGCTCAACGTCTCGCCCGCCGAGGTCGCCCGCC AAGGTTATCAGGGGCTGATGAACAACAGGCGGCTGGTGTTGCCGGGCCTCGGCGTCAAGATCGTGCCGTTCCTGCTGCGA TTCTTCCCGCGCGGCTTCATTCTGGCCGCGGTCGGCGGCTATCAGCAGCGGCAGCGCTGA
Upstream 100 bases:
>100_bases ATGGCCTTGCACGCTGCTTGCATCTTGCATAAGGCCTAGTGATGATCCGCGGGCCATCCGGCCTCTCGATTCAAGTCTTT CAATTCATGAGTCTCTCATC
Downstream 100 bases:
>100_bases AGCGCCCGCCGCGCACGGCCATCATTTGGCCCGGAGCTTGCTTTAGTAGCTGGCGACTGAGAAAACTCAATCCGTCGAGG CAATTGCACGACGGTGCGAC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 259; Mature: 258
Protein sequence:
>259_residues MTERVTLITGASAGIGTELARIFAANAHRVALVARRADRLEALAAEITAKGGKEPIIIVCDLAKPEAVDEIVARLTAAGV EVEYLVNNAGYGLFGRAAEIDREDQLGIIDVNIRALTDLSLRFADSVAKLRGGILNVASIASFLPGPGMAVYYASKAYVL SLSEALHQELGKKGVRVTAICPGPVSTEFQSRAGFEPGFDSAVLNVSPAEVARQGYQGLMNNRRLVLPGLGVKIVPFLLR FFPRGFILAAVGGYQQRQR
Sequences:
>Translated_259_residues MTERVTLITGASAGIGTELARIFAANAHRVALVARRADRLEALAAEITAKGGKEPIIIVCDLAKPEAVDEIVARLTAAGV EVEYLVNNAGYGLFGRAAEIDREDQLGIIDVNIRALTDLSLRFADSVAKLRGGILNVASIASFLPGPGMAVYYASKAYVL SLSEALHQELGKKGVRVTAICPGPVSTEFQSRAGFEPGFDSAVLNVSPAEVARQGYQGLMNNRRLVLPGLGVKIVPFLLR FFPRGFILAAVGGYQQRQR >Mature_258_residues TERVTLITGASAGIGTELARIFAANAHRVALVARRADRLEALAAEITAKGGKEPIIIVCDLAKPEAVDEIVARLTAAGVE VEYLVNNAGYGLFGRAAEIDREDQLGIIDVNIRALTDLSLRFADSVAKLRGGILNVASIASFLPGPGMAVYYASKAYVLS LSEALHQELGKKGVRVTAICPGPVSTEFQSRAGFEPGFDSAVLNVSPAEVARQGYQGLMNNRRLVLPGLGVKIVPFLLRF FPRGFILAAVGGYQQRQR
Specific function: Catalyzes the oxidation of the hydroxyl group of serine to form 2-aminomalonate semialdehyde which is spontaneously converted into 2-aminoacetaldehyde and CO(2). Also acts on D- serine, L-glycerate, D-glycerate and 2-methyl-DL-serine. Does not act on O-me
COG id: COG0300
COG function: function code R; Short-chain dehydrogenases of various substrate specificities
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705855, Length=189, Percent_Identity=31.7460317460317, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI4557649, Length=187, Percent_Identity=34.2245989304813, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=29.2929292929293, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI5031737, Length=190, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI32483357, Length=192, Percent_Identity=28.125, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI40254992, Length=188, Percent_Identity=28.7234042553192, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI109715829, Length=196, Percent_Identity=31.6326530612245, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI20149619, Length=272, Percent_Identity=26.1029411764706, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI226371731, Length=195, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=28.021978021978, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=31.9371727748691, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI7705925, Length=207, Percent_Identity=29.4685990338164, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1787820, Length=190, Percent_Identity=35.2631578947368, Blast_Score=91, Evalue=8e-20, Organism=Escherichia coli, GI87082100, Length=189, Percent_Identity=30.6878306878307, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1786701, Length=189, Percent_Identity=30.1587301587302, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787335, Length=187, Percent_Identity=28.8770053475936, Blast_Score=74, Evalue=6e-15, Organism=Escherichia coli, GI2367365, Length=189, Percent_Identity=30.6878306878307, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI87082160, Length=208, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786812, Length=133, Percent_Identity=33.8345864661654, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1789208, Length=189, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=6e-11, Organism=Escherichia coli, GI2367175, Length=210, Percent_Identity=30, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI17562908, Length=204, Percent_Identity=31.8627450980392, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI71994604, Length=202, Percent_Identity=30.6930693069307, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17559104, Length=237, Percent_Identity=29.1139240506329, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562910, Length=205, Percent_Identity=29.7560975609756, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI71994600, Length=208, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562906, Length=232, Percent_Identity=28.8793103448276, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560220, Length=201, Percent_Identity=29.3532338308458, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193204405, Length=204, Percent_Identity=30.8823529411765, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17560150, Length=200, Percent_Identity=30.5, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17563726, Length=212, Percent_Identity=26.4150943396226, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17551412, Length=200, Percent_Identity=28.5, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562990, Length=227, Percent_Identity=27.7533039647577, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI72000259, Length=194, Percent_Identity=28.3505154639175, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17560332, Length=203, Percent_Identity=28.0788177339901, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17531453, Length=191, Percent_Identity=29.8429319371728, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17562904, Length=271, Percent_Identity=25.4612546125461, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI115534694, Length=212, Percent_Identity=30.188679245283, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17538486, Length=200, Percent_Identity=27, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17538480, Length=200, Percent_Identity=25.5, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17536651, Length=196, Percent_Identity=30.6122448979592, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17544670, Length=200, Percent_Identity=31, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17536025, Length=191, Percent_Identity=29.8429319371728, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=25.7142857142857, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=33.8461538461538, Blast_Score=85, Evalue=1e-17, Organism=Saccharomyces cerevisiae, GI6319635, Length=196, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=9e-12, Organism=Saccharomyces cerevisiae, GI6322067, Length=195, Percent_Identity=27.1794871794872, Blast_Score=62, Evalue=8e-11, Organism=Drosophila melanogaster, GI28571526, Length=196, Percent_Identity=33.1632653061224, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI24584752, Length=187, Percent_Identity=36.8983957219251, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI21357041, Length=194, Percent_Identity=31.9587628865979, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI24644339, Length=193, Percent_Identity=32.1243523316062, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI23397609, Length=195, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24584744, Length=190, Percent_Identity=32.1052631578947, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI28574402, Length=190, Percent_Identity=32.1052631578947, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI24640442, Length=190, Percent_Identity=31.5789473684211, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI21358495, Length=251, Percent_Identity=26.2948207171315, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=29.1005291005291, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=29.1005291005291, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI24643142, Length=199, Percent_Identity=32.6633165829146, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24641388, Length=198, Percent_Identity=31.8181818181818, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=29.0816326530612, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI28571387, Length=196, Percent_Identity=29.5918367346939, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24641232, Length=202, Percent_Identity=30.6930693069307, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24644337, Length=195, Percent_Identity=32.3076923076923, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24580925, Length=205, Percent_Identity=29.2682926829268, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24648693, Length=208, Percent_Identity=29.8076923076923, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21355889, Length=208, Percent_Identity=29.8076923076923, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24648944, Length=198, Percent_Identity=31.8181818181818, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24639444, Length=188, Percent_Identity=28.7234042553192, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.276 [H]
Molecular weight: Translated: 27606; Mature: 27475
Theoretical pI: Translated: 9.37; Mature: 9.37
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTERVTLITGASAGIGTELARIFAANAHRVALVARRADRLEALAAEITAKGGKEPIIIVC CCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE DLAKPEAVDEIVARLTAAGVEVEYLVNNAGYGLFGRAAEIDREDQLGIIDVNIRALTDLS ECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHH LRFADSVAKLRGGILNVASIASFLPGPGMAVYYASKAYVLSLSEALHQELGKKGVRVTAI HHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCHHEEHHHHHHHHHHCCCCCEEEEE CPGPVSTEFQSRAGFEPGFDSAVLNVSPAEVARQGYQGLMNNRRLVLPGLGVKIVPFLLR CCCCCCCCHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHH FFPRGFILAAVGGYQQRQR HCCCCEEEEECCCHHHCCC >Mature Secondary Structure TERVTLITGASAGIGTELARIFAANAHRVALVARRADRLEALAAEITAKGGKEPIIIVC CCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE DLAKPEAVDEIVARLTAAGVEVEYLVNNAGYGLFGRAAEIDREDQLGIIDVNIRALTDLS ECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHH LRFADSVAKLRGGILNVASIASFLPGPGMAVYYASKAYVLSLSEALHQELGKKGVRVTAI HHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCHHEEHHHHHHHHHHCCCCCEEEEE CPGPVSTEFQSRAGFEPGFDSAVLNVSPAEVARQGYQGLMNNRRLVLPGLGVKIVPFLLR CCCCCCCCHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHH FFPRGFILAAVGGYQQRQR HCCCCEEEEECCCHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11743193; 11743194 [H]