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The map label for this gene is yciR [C]

Identifier: 86747177

GI number: 86747177

Start: 51434

End: 53662

Strand: Reverse

Name: yciR [C]

Synonym: RPB_0050

Alternate gene names: 86747177

Gene position: 53662-51434 (Counterclockwise)

Preceding gene: 86747179

Following gene: 86747175

Centisome position: 1.01

GC content: 68.1

Gene sequence:

>2229_bases
ATGCCGCAAATCCGGCTGAAGACAAGCAAGACATCGAAAAGATGCACGGTCGCGCGTAAGCCAAAGCCAAGCCGCTCCGC
GACGAAAGGCCCCAAGCCATTGCCGCGTCCGAAGCGGCCGTCGCGCGCCGCGGCGGTCGCCGATCGCGAGCGCGCCGTCG
CGGTCGCGCTGGACGAGGCCCGCAAGTCGCACGAGCGGCTGCGCGAGGCGATCGACATCCTGCCGCAGGGCATCGTGTTT
CTCGACTCCGAGGGCCGCTACATCCTCTGGAACAAGCGCTACGCCGAGATCTACAAGGCCAGCGCCGATCTGTTCAAACC
CGGCGCGCGGATCGAGGACACGATGCGTGTCGGCGTCGCGCGCGGCGACTATCCGGAGGCGGTCGGCCACGAGGAGGAAT
GGATCGCCGAGCGGATGCGGCGGCTGTTCGACCCGGGGCACAGCCACGAGCAGGTGCTCGCCGACGGTCGCTGCATCCGG
ATCGAGGAACGCACCACCTCCGACGGCGGCGTGATCGGCCTGCGCGTCGACATCACCGAGCTGAAGCAGCGCGAGGCGTC
GTTCCGGCTGATGTTCGAGGGCAATCCGGTGCCGATGATCGTGTGCTCGCTGAAGGACGAGCGCATCGTCGCGGTCAACG
ACGCCGCGGTGCTGCATTACGGCTATTCGCCCGCCGAATTCGCCGGGTTGACGATCCGTCGCCTGCAGGCGTTCGGGACC
GAGTTGCCATGGTCCGGCGAGCAGACCAACGAGGAGCGCGCGGCGCGGACCTGGACGCACGTCAAGGCCGACGGCTCGCT
GATCGATCTGGCGGTCTATGCGCGCCAGCTCACCTACAATGGCGAGCCGGCCGTGCTGCTGGCGCTGATGGACATCACCG
AACGCAAGCGCGCCGAGATGCGGCTCGCCTTCATGGCGCATCACGACGGCCTGACCAAGCTGCCGAACCGCAGCCTGCTG
CGCAAGCGGCTCGACGAATTGCTGGCCAAGACCCGGCGCACCGGCGACAAGATCGCGGTGCTGTTCATCGGCGTCGATCA
TTTCAAGGCGGTGAACGACACGCTCGGCCACGCCATCGGCGACAAGCTGCTGCGCGGCATCGCGCGGCGGCTGCGTTCGA
CGCTGCGCGAGGAGGATCCGCTGGCGCGGCTCAACTCCGACGAATTCGCGGTGATCCAGACCGGGATCAAACGACCCGAA
GACGTCACGCTGCTGGCCAAGCGGCTGCTGAATGCGATCGCCGAACCGTATCTGCTCGAGGGCCATTCGGTGGTCGCCGG
CGCCAGCATCGGCATCGCGGTCGCGCCGCTCGACGGCGACGATTCCGAGAAGCTCTTGATGAACGCCGGCATGGCGCTGT
CGCGTGCCAAGACGGATTCGCGTGGCAGCTTCAGCTTCTTCGAGCCGGACATGGACGCCCGCGCGCAGTCCCGCCGCAAG
ATCGAGACCGAGCTGCGCGCGGCGTTGCGTCACGAGGTGCTGCGGCCGTACTACCAGCCGCTGATCGCTCTGAGCGGCGG
CGGCGTCACCGGCTGCGAGGCGCTGGTGCGCTGGCCGCATCCGGAGCGCGGCATGGTCTCGCCTGGCGAATTCATCCCGG
TCGCCGAGGATACCGGCCTGATCAACGCGATCGGCGCGCAGGTGCTGCGCGCGGCCTGCCGGGACGCCGCGCGCTGGCCC
GGCGACATCAGCGTCGCGGTCAATCTGTCGCCGCTGCAGTTCCGCGTCGGCAATCTGATGGCGACGGTGATGGATGCGCT
GAAGCAATCCGGCCTGCCGCCGCGCCGGCTCGAACTCGAAATCACCGAGACGCTGCTGCTGGAGAAGAGCAGCCAGGTGA
TCGCGACGCTGCACGCGCTGCGCGCGCTCGGCGTCCGGATCTCGATGGACGATTTCGGCACCGGCTATTCGTCGCTCAGC
TATCTGCGCAGCTTTCCGTTCGACAAGATCAAGATCGACCAGTCGTTCGTCCGCGGCGTCAGCGACAATCGCGAAGCCCA
GGCGATCGTCCGCGCCATCATCAGCCTCGGCATGGGGCTCGGCGTCACCATCACCGCCGAAGGCGTCGAGACCGAAGCCG
AACTGAACTGGCTGCGCGCGGAGGGCTGCCACGAGGCGCAGGGCTTCCTGTTCAGCCCGGCGCGGCCGAACGACGAGCTC
AGGGACCTGCTCGATCGGCAGGGCACGGCCGGCGGTGCGTTCCCGGTCAGCGCGTCGCGCGTCGCGTAG

Upstream 100 bases:

>100_bases
GTGATCGCGCCCGTCGATGCAAATGCCGCTGAAACCGTTACATAATTTTTTCAGATACATCCTGCACAACCGGTTCGCAA
AGTGCGTATGGGGCGTGGGA

Downstream 100 bases:

>100_bases
CGGCTAGTTCGCGGGTTCCCGGGCCGGCGTCGGAGCGGGCGCTTGGTGATGGAGGGCGGTATCCATCACTTGCGCATCGC
AAGCCGCCGCTTCCGCGTCA

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 742; Mature: 741

Protein sequence:

>742_residues
MPQIRLKTSKTSKRCTVARKPKPSRSATKGPKPLPRPKRPSRAAAVADRERAVAVALDEARKSHERLREAIDILPQGIVF
LDSEGRYILWNKRYAEIYKASADLFKPGARIEDTMRVGVARGDYPEAVGHEEEWIAERMRRLFDPGHSHEQVLADGRCIR
IEERTTSDGGVIGLRVDITELKQREASFRLMFEGNPVPMIVCSLKDERIVAVNDAAVLHYGYSPAEFAGLTIRRLQAFGT
ELPWSGEQTNEERAARTWTHVKADGSLIDLAVYARQLTYNGEPAVLLALMDITERKRAEMRLAFMAHHDGLTKLPNRSLL
RKRLDELLAKTRRTGDKIAVLFIGVDHFKAVNDTLGHAIGDKLLRGIARRLRSTLREEDPLARLNSDEFAVIQTGIKRPE
DVTLLAKRLLNAIAEPYLLEGHSVVAGASIGIAVAPLDGDDSEKLLMNAGMALSRAKTDSRGSFSFFEPDMDARAQSRRK
IETELRAALRHEVLRPYYQPLIALSGGGVTGCEALVRWPHPERGMVSPGEFIPVAEDTGLINAIGAQVLRAACRDAARWP
GDISVAVNLSPLQFRVGNLMATVMDALKQSGLPPRRLELEITETLLLEKSSQVIATLHALRALGVRISMDDFGTGYSSLS
YLRSFPFDKIKIDQSFVRGVSDNREAQAIVRAIISLGMGLGVTITAEGVETEAELNWLRAEGCHEAQGFLFSPARPNDEL
RDLLDRQGTAGGAFPVSASRVA

Sequences:

>Translated_742_residues
MPQIRLKTSKTSKRCTVARKPKPSRSATKGPKPLPRPKRPSRAAAVADRERAVAVALDEARKSHERLREAIDILPQGIVF
LDSEGRYILWNKRYAEIYKASADLFKPGARIEDTMRVGVARGDYPEAVGHEEEWIAERMRRLFDPGHSHEQVLADGRCIR
IEERTTSDGGVIGLRVDITELKQREASFRLMFEGNPVPMIVCSLKDERIVAVNDAAVLHYGYSPAEFAGLTIRRLQAFGT
ELPWSGEQTNEERAARTWTHVKADGSLIDLAVYARQLTYNGEPAVLLALMDITERKRAEMRLAFMAHHDGLTKLPNRSLL
RKRLDELLAKTRRTGDKIAVLFIGVDHFKAVNDTLGHAIGDKLLRGIARRLRSTLREEDPLARLNSDEFAVIQTGIKRPE
DVTLLAKRLLNAIAEPYLLEGHSVVAGASIGIAVAPLDGDDSEKLLMNAGMALSRAKTDSRGSFSFFEPDMDARAQSRRK
IETELRAALRHEVLRPYYQPLIALSGGGVTGCEALVRWPHPERGMVSPGEFIPVAEDTGLINAIGAQVLRAACRDAARWP
GDISVAVNLSPLQFRVGNLMATVMDALKQSGLPPRRLELEITETLLLEKSSQVIATLHALRALGVRISMDDFGTGYSSLS
YLRSFPFDKIKIDQSFVRGVSDNREAQAIVRAIISLGMGLGVTITAEGVETEAELNWLRAEGCHEAQGFLFSPARPNDEL
RDLLDRQGTAGGAFPVSASRVA
>Mature_741_residues
PQIRLKTSKTSKRCTVARKPKPSRSATKGPKPLPRPKRPSRAAAVADRERAVAVALDEARKSHERLREAIDILPQGIVFL
DSEGRYILWNKRYAEIYKASADLFKPGARIEDTMRVGVARGDYPEAVGHEEEWIAERMRRLFDPGHSHEQVLADGRCIRI
EERTTSDGGVIGLRVDITELKQREASFRLMFEGNPVPMIVCSLKDERIVAVNDAAVLHYGYSPAEFAGLTIRRLQAFGTE
LPWSGEQTNEERAARTWTHVKADGSLIDLAVYARQLTYNGEPAVLLALMDITERKRAEMRLAFMAHHDGLTKLPNRSLLR
KRLDELLAKTRRTGDKIAVLFIGVDHFKAVNDTLGHAIGDKLLRGIARRLRSTLREEDPLARLNSDEFAVIQTGIKRPED
VTLLAKRLLNAIAEPYLLEGHSVVAGASIGIAVAPLDGDDSEKLLMNAGMALSRAKTDSRGSFSFFEPDMDARAQSRRKI
ETELRAALRHEVLRPYYQPLIALSGGGVTGCEALVRWPHPERGMVSPGEFIPVAEDTGLINAIGAQVLRAACRDAARWPG
DISVAVNLSPLQFRVGNLMATVMDALKQSGLPPRRLELEITETLLLEKSSQVIATLHALRALGVRISMDDFGTGYSSLSY
LRSFPFDKIKIDQSFVRGVSDNREAQAIVRAIISLGMGLGVTITAEGVETEAELNWLRAEGCHEAQGFLFSPARPNDELR
DLLDRQGTAGGAFPVSASRVA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=454, Percent_Identity=35.2422907488987, Blast_Score=283, Evalue=3e-77,
Organism=Escherichia coli, GI87081921, Length=431, Percent_Identity=34.338747099768, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI226510982, Length=413, Percent_Identity=31.7191283292978, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1790496, Length=236, Percent_Identity=36.4406779661017, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1786507, Length=240, Percent_Identity=32.9166666666667, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=34.4398340248963, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1787055, Length=287, Percent_Identity=31.7073170731707, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI1788381, Length=669, Percent_Identity=25.7100149476831, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI87081845, Length=250, Percent_Identity=33.2, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1788502, Length=254, Percent_Identity=31.8897637795276, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081980, Length=249, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=8e-31,
Organism=Escherichia coli, GI87082096, Length=442, Percent_Identity=25.5656108597285, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87081881, Length=287, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788849, Length=236, Percent_Identity=30.9322033898305, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1787410, Length=158, Percent_Identity=30.379746835443, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=34.2696629213483, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693134, Length=156, Percent_Identity=34.6153846153846, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789650, Length=419, Percent_Identity=21.9570405727924, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI87081977, Length=167, Percent_Identity=29.940119760479, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1787802, Length=166, Percent_Identity=28.9156626506024, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788956, Length=155, Percent_Identity=34.1935483870968, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082007, Length=164, Percent_Identity=32.9268292682927, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787262, Length=92, Percent_Identity=35.8695652173913, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 81968; Mature: 81837

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50112 PAS ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQIRLKTSKTSKRCTVARKPKPSRSATKGPKPLPRPKRPSRAAAVADRERAVAVALDEA
CCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCEEEEEHHHH
RKSHERLREAIDILPQGIVFLDSEGRYILWNKRYAEIYKASADLFKPGARIEDTMRVGVA
HHHHHHHHHHHHHCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHCCCCCCCHHHHEECC
RGDYPEAVGHEEEWIAERMRRLFDPGHSHEQVLADGRCIRIEERTTSDGGVIGLRVDITE
CCCCCHHCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEECCCCCCCCEEEEEEEHHH
LKQREASFRLMFEGNPVPMIVCSLKDERIVAVNDAAVLHYGYSPAEFAGLTIRRLQAFGT
HHHCCCCEEEEECCCCCCEEEEECCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHCC
ELPWSGEQTNEERAARTWTHVKADGSLIDLAVYARQLTYNGEPAVLLALMDITERKRAEM
CCCCCCCCCCHHHHHHHHHEEECCCCEEHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHH
RLAFMAHHDGLTKLPNRSLLRKRLDELLAKTRRTGDKIAVLFIGVDHFKAVNDTLGHAIG
HHHHHECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHH
DKLLRGIARRLRSTLREEDPLARLNSDEFAVIQTGIKRPEDVTLLAKRLLNAIAEPYLLE
HHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEHHCCCCCCHHHHHHHHHHHHHCCCEEEC
GHSVVAGASIGIAVAPLDGDDSEKLLMNAGMALSRAKTDSRGSFSFFEPDMDARAQSRRK
CCCEEEECCCCEEEEECCCCCCHHHHHHCCCHHHHCCCCCCCCCEECCCCCCHHHHHHHH
IETELRAALRHEVLRPYYQPLIALSGGGVTGCEALVRWPHPERGMVSPGEFIPVAEDTGL
HHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCCCCCCCCCCCCEEECCCCCCH
INAIGAQVLRAACRDAARWPGDISVAVNLSPLQFRVGNLMATVMDALKQSGLPPRRLELE
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
ITETLLLEKSSQVIATLHALRALGVRISMDDFGTGYSSLSYLRSFPFDKIKIDQSFVRGV
EHHHHHHCCCHHHHHHHHHHHHHCCEEEEHHCCCCHHHHHHHHHCCCCEEEECHHHHCCC
SDNREAQAIVRAIISLGMGLGVTITAEGVETEAELNWLRAEGCHEAQGFLFSPARPNDEL
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEECCCCCCHHH
RDLLDRQGTAGGAFPVSASRVA
HHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PQIRLKTSKTSKRCTVARKPKPSRSATKGPKPLPRPKRPSRAAAVADRERAVAVALDEA
CCEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCEEEEEHHHH
RKSHERLREAIDILPQGIVFLDSEGRYILWNKRYAEIYKASADLFKPGARIEDTMRVGVA
HHHHHHHHHHHHHCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHCCCCCCCHHHHEECC
RGDYPEAVGHEEEWIAERMRRLFDPGHSHEQVLADGRCIRIEERTTSDGGVIGLRVDITE
CCCCCHHCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEECCCCCCCCEEEEEEEHHH
LKQREASFRLMFEGNPVPMIVCSLKDERIVAVNDAAVLHYGYSPAEFAGLTIRRLQAFGT
HHHCCCCEEEEECCCCCCEEEEECCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHCC
ELPWSGEQTNEERAARTWTHVKADGSLIDLAVYARQLTYNGEPAVLLALMDITERKRAEM
CCCCCCCCCCHHHHHHHHHEEECCCCEEHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHH
RLAFMAHHDGLTKLPNRSLLRKRLDELLAKTRRTGDKIAVLFIGVDHFKAVNDTLGHAIG
HHHHHECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHH
DKLLRGIARRLRSTLREEDPLARLNSDEFAVIQTGIKRPEDVTLLAKRLLNAIAEPYLLE
HHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEHHCCCCCCHHHHHHHHHHHHHCCCEEEC
GHSVVAGASIGIAVAPLDGDDSEKLLMNAGMALSRAKTDSRGSFSFFEPDMDARAQSRRK
CCCEEEECCCCEEEEECCCCCCHHHHHHCCCHHHHCCCCCCCCCEECCCCCCHHHHHHHH
IETELRAALRHEVLRPYYQPLIALSGGGVTGCEALVRWPHPERGMVSPGEFIPVAEDTGL
HHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCCCCCCCCCCCCEEECCCCCCH
INAIGAQVLRAACRDAARWPGDISVAVNLSPLQFRVGNLMATVMDALKQSGLPPRRLELE
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
ITETLLLEKSSQVIATLHALRALGVRISMDDFGTGYSSLSYLRSFPFDKIKIDQSFVRGV
EHHHHHHCCCHHHHHHHHHHHHHCCEEEEHHCCCCHHHHHHHHHCCCCEEEECHHHHCCC
SDNREAQAIVRAIISLGMGLGVTITAEGVETEAELNWLRAEGCHEAQGFLFSPARPNDEL
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEECCCCCCHHH
RDLLDRQGTAGGAFPVSASRVA
HHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]