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The map label for this gene is aroB [H]

Identifier: 86609035

GI number: 86609035

Start: 1641822

End: 1642958

Strand: Reverse

Name: aroB [H]

Synonym: CYB_1570

Alternate gene names: 86609035

Gene position: 1642958-1641822 (Counterclockwise)

Preceding gene: 86609036

Following gene: 86609034

Centisome position: 53.93

GC content: 61.83

Gene sequence:

>1137_bases
ATGGATCTCTATCTGATCCCTGTCAAGCTTCCCCACAGCTCCTACGATATTCTCCTCCAGTCTGCCGAAGGCCCCCCTGG
CCACAGCCTCATCCAGCTGGGATCCCAAATGCGAGCTAGAGGGCTTTCCGGCAAGGCTCTGGTGGTGAGCCATCCCGGCA
TTGCCAAACACTTTGCCGAGAAGTTGCTGCAGGGGCTGCAACAAGCGGGGTTTGCCGCCCACCTCTGCCTATTGCCTGCC
GGCGAACGCTACAAAACCCTGCGCTCGGTGGCCAAGATCTACGACGCCGCCCTAGCCTTTGGCCTGGAGCGCTCCTCCAC
CTTGGTGGCTCTAGGAGGGGGGGTCATTGGCGACATGGTGGGGTTTGCTGCCGCCACCTGGCTGCGCGGGATCCCTTTTG
TGCAGGTGCCCACCTCACTTTTGGCCATGGTGGATGCGGCCATCGGCGGCAAGACCGGTGTCAACCATCCTGGCGGGAAA
AACCTCATTGGGGCGTTTTATCAGCCGCGCCTGGTGTGGATTGACCCGACGGTGCTGAAAACTCTGCCCCCACGGGAGTT
TACTTCGGCTTTGGCAGAGGTGATCAAATACGGCGTGATTCAGGCTGCCGACCTATTTGAGTTTTTGGAAGATCGACCCC
AACTGAGCCGCTATACCGACTTTACTCCCGCAGACTTGCACTACCTGCTGCGCCGCTGTGCCGAGTGCAAAGCCTGGGTG
GTGCAGCAGGACGAGAAAGAAGCGGGCCTGCGGGCCATCCTCAACTACGGCCATACCCTCGGCCATGCCCTAGAAGCTGC
CACCGGCTACCGCCGCTATCTGCACGGAGAAGCTGTCGCCATCGGCATGGTAGCTGCCGGGGAGATCGCCCGCCGCCTGG
GTTGGTGGAGCGCCGCCGAGGCGGAGCGGCAACGACGCCTGATCGAGAAAGCAGGATTGCCCAGCCGGTGGCCTGCCGGG
ATCCCTTGGGAGGCAGTGCTGCAGGCAATGCAGGCCGACAAGAAAGTCAAACAGGGGCGGATTCGCTTCGTTCTGCCCCG
CCGCATCGGCCAGGCCGAGCTGACCGACCAGGTGGAATTGGCAGACATTCAGGCGGCTGTAGAATCCGTTACCCTCCCAG
CTTTAGGGGCGTCTTGA

Upstream 100 bases:

>100_bases
CAGGATCCCCTGGGCTTTCAGACCCCAAGGACAATGCCTGCAGCAGGCAGACGGGAGCAGAACATGCCACACTGGATCCC
GCCCCCCAGGACCGACACGC

Downstream 100 bases:

>100_bases
GCCTTAAAATAAGGGGACTTGAGGATGGCAAAGCATGGGACGGCAACAACGGGTAGCCATTTTGGGAGCAACAGGGGCAG
TAGGGGCAGAGCTGCTGATG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MDLYLIPVKLPHSSYDILLQSAEGPPGHSLIQLGSQMRARGLSGKALVVSHPGIAKHFAEKLLQGLQQAGFAAHLCLLPA
GERYKTLRSVAKIYDAALAFGLERSSTLVALGGGVIGDMVGFAAATWLRGIPFVQVPTSLLAMVDAAIGGKTGVNHPGGK
NLIGAFYQPRLVWIDPTVLKTLPPREFTSALAEVIKYGVIQAADLFEFLEDRPQLSRYTDFTPADLHYLLRRCAECKAWV
VQQDEKEAGLRAILNYGHTLGHALEAATGYRRYLHGEAVAIGMVAAGEIARRLGWWSAAEAERQRRLIEKAGLPSRWPAG
IPWEAVLQAMQADKKVKQGRIRFVLPRRIGQAELTDQVELADIQAAVESVTLPALGAS

Sequences:

>Translated_378_residues
MDLYLIPVKLPHSSYDILLQSAEGPPGHSLIQLGSQMRARGLSGKALVVSHPGIAKHFAEKLLQGLQQAGFAAHLCLLPA
GERYKTLRSVAKIYDAALAFGLERSSTLVALGGGVIGDMVGFAAATWLRGIPFVQVPTSLLAMVDAAIGGKTGVNHPGGK
NLIGAFYQPRLVWIDPTVLKTLPPREFTSALAEVIKYGVIQAADLFEFLEDRPQLSRYTDFTPADLHYLLRRCAECKAWV
VQQDEKEAGLRAILNYGHTLGHALEAATGYRRYLHGEAVAIGMVAAGEIARRLGWWSAAEAERQRRLIEKAGLPSRWPAG
IPWEAVLQAMQADKKVKQGRIRFVLPRRIGQAELTDQVELADIQAAVESVTLPALGAS
>Mature_378_residues
MDLYLIPVKLPHSSYDILLQSAEGPPGHSLIQLGSQMRARGLSGKALVVSHPGIAKHFAEKLLQGLQQAGFAAHLCLLPA
GERYKTLRSVAKIYDAALAFGLERSSTLVALGGGVIGDMVGFAAATWLRGIPFVQVPTSLLAMVDAAIGGKTGVNHPGGK
NLIGAFYQPRLVWIDPTVLKTLPPREFTSALAEVIKYGVIQAADLFEFLEDRPQLSRYTDFTPADLHYLLRRCAECKAWV
VQQDEKEAGLRAILNYGHTLGHALEAATGYRRYLHGEAVAIGMVAAGEIARRLGWWSAAEAERQRRLIEKAGLPSRWPAG
IPWEAVLQAMQADKKVKQGRIRFVLPRRIGQAELTDQVELADIQAAVESVTLPALGAS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=329, Percent_Identity=47.7203647416413, Blast_Score=280, Evalue=9e-77,
Organism=Saccharomyces cerevisiae, GI6320332, Length=306, Percent_Identity=38.562091503268, Blast_Score=201, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 41020; Mature: 41020

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLYLIPVKLPHSSYDILLQSAEGPPGHSLIQLGSQMRARGLSGKALVVSHPGIAKHFAE
CCEEEEEEECCCCCHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHH
KLLQGLQQAGFAAHLCLLPAGERYKTLRSVAKIYDAALAFGLERSSTLVALGGGVIGDMV
HHHHHHHHCCHHEEHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHH
GFAAATWLRGIPFVQVPTSLLAMVDAAIGGKTGVNHPGGKNLIGAFYQPRLVWIDPTVLK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCEEEEECHHHHH
TLPPREFTSALAEVIKYGVIQAADLFEFLEDRPQLSRYTDFTPADLHYLLRRCAECKAWV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHH
VQQDEKEAGLRAILNYGHTLGHALEAATGYRRYLHGEAVAIGMVAAGEIARRLGWWSAAE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHH
AERQRRLIEKAGLPSRWPAGIPWEAVLQAMQADKKVKQGRIRFVLPRRIGQAELTDQVEL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHCCCHHH
ADIQAAVESVTLPALGAS
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDLYLIPVKLPHSSYDILLQSAEGPPGHSLIQLGSQMRARGLSGKALVVSHPGIAKHFAE
CCEEEEEEECCCCCHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHH
KLLQGLQQAGFAAHLCLLPAGERYKTLRSVAKIYDAALAFGLERSSTLVALGGGVIGDMV
HHHHHHHHCCHHEEHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHH
GFAAATWLRGIPFVQVPTSLLAMVDAAIGGKTGVNHPGGKNLIGAFYQPRLVWIDPTVLK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCEEEEECHHHHH
TLPPREFTSALAEVIKYGVIQAADLFEFLEDRPQLSRYTDFTPADLHYLLRRCAECKAWV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHH
VQQDEKEAGLRAILNYGHTLGHALEAATGYRRYLHGEAVAIGMVAAGEIARRLGWWSAAE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHH
AERQRRLIEKAGLPSRWPAGIPWEAVLQAMQADKKVKQGRIRFVLPRRIGQAELTDQVEL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHCCCHHH
ADIQAAVESVTLPALGAS
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA