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The map label for this gene is ubiH [C]

Identifier: 86608456

GI number: 86608456

Start: 1012024

End: 1013241

Strand: Direct

Name: ubiH [C]

Synonym: CYB_0978

Alternate gene names: 86608456

Gene position: 1012024-1013241 (Clockwise)

Preceding gene: 86608455

Following gene: 86608458

Centisome position: 33.22

GC content: 63.96

Gene sequence:

>1218_bases
ATGACAACTCTTGCTCCCACTCCGGATACTTTGGCAGCCCTCTACGACGTGATTATCGTCGGCGGAGGCATCGCGGGCTT
AACCCTAGCTTGTGCCCTGCGGGGATCCGGCCTGCGGTTGGCCCTCATTGAGGCCCAGTCGGCTGAGGCAGTCAAACAGC
GCCCCCTGGCCTATGCCCTTTCGCCGCTGTCAATCCGCATCTTCCGGGCCGTCGGGGTGTGGGAGGCGCTGGCTCCCCAC
ATTACGCCCTTTGCTCAGGTGATTTTAACCGACGCCAACGCTCCCCAGCGGGTGACGTTTAGACCGGAGGATGTGGGGGA
AGCGGCAGTTTTCTACTGTGGCGAGCATGCCTGGCTGCAGCAGGCGCTCCAGGAGCAGGTGGCTGCCGATCCCAAAATTA
GCTGCTACTACGAAGCCAAGGTGGAGAGCGTAACCTATGGGAAGGCTGCAGCCGAGGTAGAGCTGGAAACGGCCCAGGGG
CGTCGCCAACTGCGGGCCTCCCTGGTGGTCGCCGCCGACGGCCTGCGCTCCCAGGTGCGGCAGTGGGCAGGGATCCCTAG
CGACGGCTGGGACTATTGGCAGTCCTGCATCACCGCCTTGGTGGCCCCTTCCCAAGACCACCAAAACATTGCCTACGAGC
GCTTCTGGCCTGCCGGCCCCTTCGCCATCTTGCCCCTGCCCGGCAACCGCTGTCAGGTGGTCTGGATCATGCCCCACGAG
CAGGCCAAAGCCACCCTGGCCCTTCCTCAGGCCGACTTCTTGGCCGAGATGCAGCGCTACTACGGCGGTCAGAGCGGCCA
GCTCACTTTGCTGAACCGGCCCCAGGTTTTCCCGGCTCGCCTACGGCAAAGCCGCCGCTACTATCAGCATCGTCTTGCCT
TAGTGGGAGATGCCGCCCACCACTGCCATCCGGTGGCTGGCCAAGGGCTCAACCTCGGCATCCGCGACGCCGCTGCCCTG
GCCCAGGTGCTCCTAGACGCCTGGAGACGGCATGAGGATCTGGGAGATGTCAAAGTCCTGCGCCGCTACGGTCGCCGTCG
CCGCTGGGAAAACTGGGTGGTGCTGCTCTTCACGGATCTGCTCACCCGCACTTTCTCCAACTCCTACTGGCCCGTAGTGG
TTATGCGGCGGTGGATCCTGAGAGGGATGATGGCCTTCCCCCCCCTGCGGTGCTTGCTGCTGTGCTTGATGACGGGACTT
TGGGGGAGCTCTCCCTAA

Upstream 100 bases:

>100_bases
TGCCGCTTTGGCATGTTCCGGGCCGTGCGAGCCGCCACGTCGGCAGACTCCACCCGCACAGAAGTGGTTGCCCACAGCAG
CCAATAGGAGAATAAGAGAG

Downstream 100 bases:

>100_bases
AGTCCCAGCTCCTCCTTGGCCTTCTGAGCGGCCAGGAGCACCTCCGCATCTTCGGCCTGCGACCAGTCGGGGTCGGCGAT
CTCGGCGTAGAACCTTTGGT

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTTLAPTPDTLAALYDVIIVGGGIAGLTLACALRGSGLRLALIEAQSAEAVKQRPLAYALSPLSIRIFRAVGVWEALAPH
ITPFAQVILTDANAPQRVTFRPEDVGEAAVFYCGEHAWLQQALQEQVAADPKISCYYEAKVESVTYGKAAAEVELETAQG
RRQLRASLVVAADGLRSQVRQWAGIPSDGWDYWQSCITALVAPSQDHQNIAYERFWPAGPFAILPLPGNRCQVVWIMPHE
QAKATLALPQADFLAEMQRYYGGQSGQLTLLNRPQVFPARLRQSRRYYQHRLALVGDAAHHCHPVAGQGLNLGIRDAAAL
AQVLLDAWRRHEDLGDVKVLRRYGRRRRWENWVVLLFTDLLTRTFSNSYWPVVVMRRWILRGMMAFPPLRCLLLCLMTGL
WGSSP

Sequences:

>Translated_405_residues
MTTLAPTPDTLAALYDVIIVGGGIAGLTLACALRGSGLRLALIEAQSAEAVKQRPLAYALSPLSIRIFRAVGVWEALAPH
ITPFAQVILTDANAPQRVTFRPEDVGEAAVFYCGEHAWLQQALQEQVAADPKISCYYEAKVESVTYGKAAAEVELETAQG
RRQLRASLVVAADGLRSQVRQWAGIPSDGWDYWQSCITALVAPSQDHQNIAYERFWPAGPFAILPLPGNRCQVVWIMPHE
QAKATLALPQADFLAEMQRYYGGQSGQLTLLNRPQVFPARLRQSRRYYQHRLALVGDAAHHCHPVAGQGLNLGIRDAAAL
AQVLLDAWRRHEDLGDVKVLRRYGRRRRWENWVVLLFTDLLTRTFSNSYWPVVVMRRWILRGMMAFPPLRCLLLCLMTGL
WGSSP
>Mature_404_residues
TTLAPTPDTLAALYDVIIVGGGIAGLTLACALRGSGLRLALIEAQSAEAVKQRPLAYALSPLSIRIFRAVGVWEALAPHI
TPFAQVILTDANAPQRVTFRPEDVGEAAVFYCGEHAWLQQALQEQVAADPKISCYYEAKVESVTYGKAAAEVELETAQGR
RQLRASLVVAADGLRSQVRQWAGIPSDGWDYWQSCITALVAPSQDHQNIAYERFWPAGPFAILPLPGNRCQVVWIMPHEQ
AKATLALPQADFLAEMQRYYGGQSGQLTLLNRPQVFPARLRQSRRYYQHRLALVGDAAHHCHPVAGQGLNLGIRDAAALA
QVLLDAWRRHEDLGDVKVLRRYGRRRRWENWVVLLFTDLLTRTFSNSYWPVVVMRRWILRGMMAFPPLRCLLLCLMTGLW
GSSP

Specific function: Oxygenase That Introduces The Hydroxyl Group At Carbon Four Of 2-Octaprenyl-6-Methoxyphenol Resulting In The Formation Of 2-Octaprenyl-6-Methoxy-1,4-Benzoquinone. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=428, Percent_Identity=27.803738317757, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI32967307, Length=379, Percent_Identity=27.9683377308707, Blast_Score=142, Evalue=6e-34,
Organism=Escherichia coli, GI1789274, Length=384, Percent_Identity=35.15625, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1786883, Length=375, Percent_Identity=34.4, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789273, Length=364, Percent_Identity=31.8681318681319, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI1786543, Length=313, Percent_Identity=26.517571884984, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25146631, Length=436, Percent_Identity=27.0642201834862, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6321694, Length=465, Percent_Identity=25.5913978494624, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19920760, Length=374, Percent_Identity=24.8663101604278, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 45131; Mature: 44999

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLAPTPDTLAALYDVIIVGGGIAGLTLACALRGSGLRLALIEAQSAEAVKQRPLAYAL
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHCCHHEEC
SPLSIRIFRAVGVWEALAPHITPFAQVILTDANAPQRVTFRPEDVGEAAVFYCGEHAWLQ
CCHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCEEEECCCCCCCEEEEEECCHHHHH
QALQEQVAADPKISCYYEAKVESVTYGKAAAEVELETAQGRRQLRASLVVAADGLRSQVR
HHHHHHHCCCCCEEEEEEEEECEEECCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
QWAGIPSDGWDYWQSCITALVAPSQDHQNIAYERFWPAGPFAILPLPGNRCQVVWIMPHE
HHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEEECCCCCEEEEEEECCC
QAKATLALPQADFLAEMQRYYGGQSGQLTLLNRPQVFPARLRQSRRYYQHRLALVGDAAH
CCCEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHH
HCHPVAGQGLNLGIRDAAALAQVLLDAWRRHEDLGDVKVLRRYGRRRRWENWVVLLFTDL
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHH
LTRTFSNSYWPVVVMRRWILRGMMAFPPLRCLLLCLMTGLWGSSP
HHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TTLAPTPDTLAALYDVIIVGGGIAGLTLACALRGSGLRLALIEAQSAEAVKQRPLAYAL
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHCCHHEEC
SPLSIRIFRAVGVWEALAPHITPFAQVILTDANAPQRVTFRPEDVGEAAVFYCGEHAWLQ
CCHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCEEEECCCCCCCEEEEEECCHHHHH
QALQEQVAADPKISCYYEAKVESVTYGKAAAEVELETAQGRRQLRASLVVAADGLRSQVR
HHHHHHHCCCCCEEEEEEEEECEEECCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
QWAGIPSDGWDYWQSCITALVAPSQDHQNIAYERFWPAGPFAILPLPGNRCQVVWIMPHE
HHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEEECCCCCEEEEEEECCC
QAKATLALPQADFLAEMQRYYGGQSGQLTLLNRPQVFPARLRQSRRYYQHRLALVGDAAH
CCCEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHH
HCHPVAGQGLNLGIRDAAALAQVLLDAWRRHEDLGDVKVLRRYGRRRRWENWVVLLFTDL
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHH
LTRTFSNSYWPVVVMRRWILRGMMAFPPLRCLLLCLMTGLWGSSP
HHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]