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The map label for this gene is hemK [C]

Identifier: 86608445

GI number: 86608445

Start: 1002317

End: 1003060

Strand: Reverse

Name: hemK [C]

Synonym: CYB_0966

Alternate gene names: 86608445

Gene position: 1003060-1002317 (Counterclockwise)

Preceding gene: 86608446

Following gene: 86608444

Centisome position: 32.92

GC content: 63.17

Gene sequence:

>744_bases
ATGGGTCGCGCTCCGGCTGGGGAGGGGGATCCCCTGGAGGAGGTGCAGGCCCTTTGGCGGCAAAGGGTGGAAGAGCGCAT
CCCCCTACAGTACCTGTTGGGCAAAGTTGAGTGGGCGGGCTTGAGCTTGCGGGTGACGCCGGCGGTGCTGATCCCGCGCC
CGGAGACCGAGCTGCTGGTGGAGCAGGCTTCCCTTTGGCTACAGGCCAATCCTCTGCCGCCGGGATCCTGTTTTGCCGAC
CTGGGTACAGGCAGCGGAGCGATTGCCATTGCGTTGGCCCATCAGCACCCCCAGTTGCGGCTTCTGGCCGTGGATTCTAG
CCCAGAGGCATTGGCTGTTGCGGCAGACAATGTGGTAGCCCACCATCTGCAGGAGCGGGTGAACTTGCTGCTGGGATCCT
GGTTTGTACCTTTGGATCCCTGGCGAGGACGGCTGCGCGGCCTGGTTTCCAACCCTCCCTACATTCCCTCTGCCGACCTG
GCCTCGCTCATGCCAGAGGTGCGACTGCACGAGCCGCGACAGGCTCTGGATGGCGGAGAAGATGGCCTAGCCCACTTGCG
ACTGTTGATTCAAGCAGCACCGGATTACCTGGCCCCGAACTCCTTTTGGGCGGTGGAAGTGATGCGAGGCCAAGCCCCTT
GGGTGGCGGAGCAGTTGCAAGCTAGAAGCTGCTATCGGCAGATCCAAGTTCACCGAGATCTGGCCGGGGTTGAACGGGTG
GTCAGCGCCCACTTCGTCGGATAG

Upstream 100 bases:

>100_bases
TGCCCAAGCCCTGAGGGCGGCAAAAGCGGCTGGGATCCCTGCCGAGGAAGTGGACATTTTGCTCAAAGAACGGCTGGGGT
GGGGGCCGTTGGAGCGGCTG

Downstream 100 bases:

>100_bases
AAAAGGGTAGGATCCCATAAGATGGGGTATCGCCGGAGCCGGAACTGTCCAAAACTTAAAGCTCCGAGCCCAGAGATCTG
AGCACGGATGGGATCCCCTG

Product: HemK family methyltransferase

Products: NA

Alternate protein names: M.Ssp6803HemKP [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MGRAPAGEGDPLEEVQALWRQRVEERIPLQYLLGKVEWAGLSLRVTPAVLIPRPETELLVEQASLWLQANPLPPGSCFAD
LGTGSGAIAIALAHQHPQLRLLAVDSSPEALAVAADNVVAHHLQERVNLLLGSWFVPLDPWRGRLRGLVSNPPYIPSADL
ASLMPEVRLHEPRQALDGGEDGLAHLRLLIQAAPDYLAPNSFWAVEVMRGQAPWVAEQLQARSCYRQIQVHRDLAGVERV
VSAHFVG

Sequences:

>Translated_247_residues
MGRAPAGEGDPLEEVQALWRQRVEERIPLQYLLGKVEWAGLSLRVTPAVLIPRPETELLVEQASLWLQANPLPPGSCFAD
LGTGSGAIAIALAHQHPQLRLLAVDSSPEALAVAADNVVAHHLQERVNLLLGSWFVPLDPWRGRLRGLVSNPPYIPSADL
ASLMPEVRLHEPRQALDGGEDGLAHLRLLIQAAPDYLAPNSFWAVEVMRGQAPWVAEQLQARSCYRQIQVHRDLAGVERV
VSAHFVG
>Mature_246_residues
GRAPAGEGDPLEEVQALWRQRVEERIPLQYLLGKVEWAGLSLRVTPAVLIPRPETELLVEQASLWLQANPLPPGSCFADL
GTGSGAIAIALAHQHPQLRLLAVDSSPEALAVAADNVVAHHLQERVNLLLGSWFVPLDPWRGRLRGLVSNPPYIPSADLA
SLMPEVRLHEPRQALDGGEDGLAHLRLLIQAAPDYLAPNSFWAVEVMRGQAPWVAEQLQARSCYRQIQVHRDLAGVERVV
SAHFVG

Specific function: Probable protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=233, Percent_Identity=35.6223175965665, Blast_Score=111, Evalue=7e-25,
Organism=Escherichia coli, GI1787463, Length=230, Percent_Identity=36.5217391304348, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI87082085, Length=188, Percent_Identity=38.2978723404255, Blast_Score=102, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324266, Length=164, Percent_Identity=30.4878048780488, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24582226, Length=194, Percent_Identity=30.9278350515464, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR019874
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.-

Molecular weight: Translated: 27059; Mature: 26928

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRAPAGEGDPLEEVQALWRQRVEERIPLQYLLGKVEWAGLSLRVTPAVLIPRPETELLV
CCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCEECCEEEEECCEEEECCCCHHHHH
EQASLWLQANPLPPGSCFADLGTGSGAIAIALAHQHPQLRLLAVDSSPEALAVAADNVVA
HHHHHEEECCCCCCCCHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEHHHHHH
HHLQERVNLLLGSWFVPLDPWRGRLRGLVSNPPYIPSADLASLMPEVRLHEPRQALDGGE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHCCHHHCCCCHHHHCCCC
DGLAHLRLLIQAAPDYLAPNSFWAVEVMRGQAPWVAEQLQARSCYRQIQVHRDLAGVERV
HHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSAHFVG
HHHHCCC
>Mature Secondary Structure 
GRAPAGEGDPLEEVQALWRQRVEERIPLQYLLGKVEWAGLSLRVTPAVLIPRPETELLV
CCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCEECCEEEEECCEEEECCCCHHHHH
EQASLWLQANPLPPGSCFADLGTGSGAIAIALAHQHPQLRLLAVDSSPEALAVAADNVVA
HHHHHEEECCCCCCCCHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEHHHHHH
HHLQERVNLLLGSWFVPLDPWRGRLRGLVSNPPYIPSADLASLMPEVRLHEPRQALDGGE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHCCHHHCCCCHHHHCCCC
DGLAHLRLLIQAAPDYLAPNSFWAVEVMRGQAPWVAEQLQARSCYRQIQVHRDLAGVERV
HHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSAHFVG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]