Click here to switch to the map view.

The map label for this gene is uvrB [H]

Identifier: 86608289

GI number: 86608289

Start: 833613

End: 835700

Strand: Direct

Name: uvrB [H]

Synonym: CYB_0807

Alternate gene names: 86608289

Gene position: 833613-835700 (Clockwise)

Preceding gene: 86608287

Following gene: 86608290

Centisome position: 27.36

GC content: 53.54

Gene sequence:

>2088_bases
ATGTCAGAGTTTCAACTGGTTTCTCCCTATCAACCCACCGGAGATCAACCTAAGGCAATTGCCGGCTTGGTGAAGTCGAT
TTCAGAAGGCCATCGTTTTCAAACCTTGCTGGGAGCAACCGGAACCGGCAAAACGTTTACCATCGCCCATACCATTCAGC
AGGTAGGCAGGCCCACCTTAGTGATGGCCCACAATAAGACTTTGGCAGCACAACTGTGCAATGAGCTGCGGGAGCTTTTT
CCTCACAATGCCGTTGAATACTTCATCAGCTATTACGACTACTATCAACCGGAAGCCTATGTTCCCAGCACCGATACATA
CATTGCCAAATCTTCTTCCATCAACGATGAAATCGATATGTTGCGGCACTCGGCTACCCGCTCTTTGTTTGAACGGCGAG
ATGTGATTGTGGTGGCCTCGGTGAGCTGCATCTATGGTCTGGGCATGCCAGAGGAGTACCTGAAGGCTTCCATCCCCTTC
AAAGTCGGCCAGGAGATTAACCAACGGGATGTCCTGCGGGATCTGGCCAGCATCCAGTACGAGCGCAATGACCTGGAGCT
GGTGCGGGGGCGATTTCGCCTCAAAGGGGATGTGCTGGAAATTGTGCCGGCCTATGAGGATCGGGTCATTCGCATCGAAT
TTTTTGGCGATGAGATCGAGGCCATTCGCTTAATTGATCCGGTTACAGGTGAGATTTTGAACAGCCTCAGCGCCCTCAGA
GTTTATCCTGCTCGGCACTTTGTAACGCCGGAAGCACAATTGGAGCGGGCGATCCTCAATATCGAGCAAGAACTGGAAGA
GCAACTGGCCCTCTTTCGCAAAGAAGGCAAGCTCCTGGAAGCCCAACGCCTAGAGCAGCGCACCCGCTACGACCTAGAAA
TGCTGCGGGAGGTGGGCTATTGCAATGGGATCGAAAACTACTCTAGACATTTAACGGGACGCAAAGCAGGAGAGCCCCCC
GCCTGCTTGGTGGATTATTTCAAGGCCGACGATTGGCTGTTGGTGGTGGATGAGTCCCACGTCACTGTGCCCCAAATTCG
CGGCATGTATAATGGCGACCGTGCCCGCAAGCAGGTGCTGGTGGATCACGGTTTTCGCCTGCCCAGCGCCCTCGACAATC
GCCCCCTCAAAGCCGAAGAATTTTGGGCCAAGGTTCATCAGTGTATCTTTGTTTCGGCTACTCCCGGCAACTGGGAACTG
GAGCAGAGCGAGGCCCAATTTGAAACCCGGGTGGAAGATGGCAAGACCTTGAAGTTTTATGTGCAGGGCAGCGGTCGGGT
TATCGAACAGGTGATTCGGCCCACTGGGGTGGTGGATCCCGAGGTGCATGTGCGCCCTACGGCTGGGCAAGTGGACGATT
TGCTGGGAGAAATTTATTTGCGATTGGAGCGCTCTCAGCTGGGGCCTGCCGAACGGGTGATCGTGACCACCCTCACCAAA
CGGATGGCAGAGGACCTCACGGAATATCTCCAGGAGCGAGGGATCCGAGTTCGCTATTTGCATTCCGAGATCACCTCGAT
TGAGCGAATTGAAATCCTACAAGACTTTCGAGAAGGGGCCTTTGACGTGTTGGTAGGAGTTAACTTGCTCCGGGAAGGGT
TGGACTTGCCAGAAGTTTCTTTGGTGGCCATTTTGGATGCCGACAAAGAAGGGTTTTTGCGAGCAGAGCGCTCCCTGATT
CAGATGATTGGGAGGGCAGCACGAAATGTCCGCGGTATGGTGGTGATGTACGCCGACACCATGACCAGCAGCATGGCCCG
GGCCATTGCCGAAACCCAGCGTCGCCGCGAAATTCAATTGCAATACAACCGCCAACACAACATCACGCCCAAGCCCATCG
TCAAGAAAAACAGCAATGCCATCTTGTCTTTTTTGGCCATCTCCCGCAAACTTAACGACCCAGATCTGGAAAAAGCCTTT
CAAGCTGCGCAAGAGATCCCTCTCTCCGAGATTCCGGAGCTGATCGGCCAACTGGAACTCAAGATGAAAGAGGCCGCCAA
AAACCTAGAATTTGAGGAAGCCGCCCAGCTACGAGATAGAATCAAAAAGCTACGTCAACGCCTTCTAGGCCACCCTCAGG
GCATCTAA

Upstream 100 bases:

>100_bases
CAAGCCTTTGTGATCCGCACTACCATTCCAAACCAACGTGCAGATCAGCCCTGCCTTGACCAGCCCGGCAGCTATCTAGG
CCCATCCGAAAGTCAAACCC

Downstream 100 bases:

>100_bases
AATCCTTGCTCAGATCGGCCAAAATTGAGGTCGGCTTGTGCCACCATGAGCTTACAGGGCAGCCCTCAGGGATCCCCAAT
TATCGATGGGCGTTCGTATC

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MSEFQLVSPYQPTGDQPKAIAGLVKSISEGHRFQTLLGATGTGKTFTIAHTIQQVGRPTLVMAHNKTLAAQLCNELRELF
PHNAVEYFISYYDYYQPEAYVPSTDTYIAKSSSINDEIDMLRHSATRSLFERRDVIVVASVSCIYGLGMPEEYLKASIPF
KVGQEINQRDVLRDLASIQYERNDLELVRGRFRLKGDVLEIVPAYEDRVIRIEFFGDEIEAIRLIDPVTGEILNSLSALR
VYPARHFVTPEAQLERAILNIEQELEEQLALFRKEGKLLEAQRLEQRTRYDLEMLREVGYCNGIENYSRHLTGRKAGEPP
ACLVDYFKADDWLLVVDESHVTVPQIRGMYNGDRARKQVLVDHGFRLPSALDNRPLKAEEFWAKVHQCIFVSATPGNWEL
EQSEAQFETRVEDGKTLKFYVQGSGRVIEQVIRPTGVVDPEVHVRPTAGQVDDLLGEIYLRLERSQLGPAERVIVTTLTK
RMAEDLTEYLQERGIRVRYLHSEITSIERIEILQDFREGAFDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRAERSLI
QMIGRAARNVRGMVVMYADTMTSSMARAIAETQRRREIQLQYNRQHNITPKPIVKKNSNAILSFLAISRKLNDPDLEKAF
QAAQEIPLSEIPELIGQLELKMKEAAKNLEFEEAAQLRDRIKKLRQRLLGHPQGI

Sequences:

>Translated_695_residues
MSEFQLVSPYQPTGDQPKAIAGLVKSISEGHRFQTLLGATGTGKTFTIAHTIQQVGRPTLVMAHNKTLAAQLCNELRELF
PHNAVEYFISYYDYYQPEAYVPSTDTYIAKSSSINDEIDMLRHSATRSLFERRDVIVVASVSCIYGLGMPEEYLKASIPF
KVGQEINQRDVLRDLASIQYERNDLELVRGRFRLKGDVLEIVPAYEDRVIRIEFFGDEIEAIRLIDPVTGEILNSLSALR
VYPARHFVTPEAQLERAILNIEQELEEQLALFRKEGKLLEAQRLEQRTRYDLEMLREVGYCNGIENYSRHLTGRKAGEPP
ACLVDYFKADDWLLVVDESHVTVPQIRGMYNGDRARKQVLVDHGFRLPSALDNRPLKAEEFWAKVHQCIFVSATPGNWEL
EQSEAQFETRVEDGKTLKFYVQGSGRVIEQVIRPTGVVDPEVHVRPTAGQVDDLLGEIYLRLERSQLGPAERVIVTTLTK
RMAEDLTEYLQERGIRVRYLHSEITSIERIEILQDFREGAFDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRAERSLI
QMIGRAARNVRGMVVMYADTMTSSMARAIAETQRRREIQLQYNRQHNITPKPIVKKNSNAILSFLAISRKLNDPDLEKAF
QAAQEIPLSEIPELIGQLELKMKEAAKNLEFEEAAQLRDRIKKLRQRLLGHPQGI
>Mature_694_residues
SEFQLVSPYQPTGDQPKAIAGLVKSISEGHRFQTLLGATGTGKTFTIAHTIQQVGRPTLVMAHNKTLAAQLCNELRELFP
HNAVEYFISYYDYYQPEAYVPSTDTYIAKSSSINDEIDMLRHSATRSLFERRDVIVVASVSCIYGLGMPEEYLKASIPFK
VGQEINQRDVLRDLASIQYERNDLELVRGRFRLKGDVLEIVPAYEDRVIRIEFFGDEIEAIRLIDPVTGEILNSLSALRV
YPARHFVTPEAQLERAILNIEQELEEQLALFRKEGKLLEAQRLEQRTRYDLEMLREVGYCNGIENYSRHLTGRKAGEPPA
CLVDYFKADDWLLVVDESHVTVPQIRGMYNGDRARKQVLVDHGFRLPSALDNRPLKAEEFWAKVHQCIFVSATPGNWELE
QSEAQFETRVEDGKTLKFYVQGSGRVIEQVIRPTGVVDPEVHVRPTAGQVDDLLGEIYLRLERSQLGPAERVIVTTLTKR
MAEDLTEYLQERGIRVRYLHSEITSIERIEILQDFREGAFDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRAERSLIQ
MIGRAARNVRGMVVMYADTMTSSMARAIAETQRRREIQLQYNRQHNITPKPIVKKNSNAILSFLAISRKLNDPDLEKAFQ
AAQEIPLSEIPELIGQLELKMKEAAKNLEFEEAAQLRDRIKKLRQRLLGHPQGI

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=702, Percent_Identity=55.1282051282051, Blast_Score=734, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 79246; Mature: 79115

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFQLVSPYQPTGDQPKAIAGLVKSISEGHRFQTLLGATGTGKTFTIAHTIQQVGRPTL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEHHHHHHHHHCCCEE
VMAHNKTLAAQLCNELRELFPHNAVEYFISYYDYYQPEAYVPSTDTYIAKSSSINDEIDM
EEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHH
LRHSATRSLFERRDVIVVASVSCIYGLGMPEEYLKASIPFKVGQEINQRDVLRDLASIQY
HHHHHHHHHHHHCCEEEEEEHHHHHCCCCCHHHHHCCCCHHHHCCCCHHHHHHHHHHHHC
ERNDLELVRGRFRLKGDVLEIVPAYEDRVIRIEFFGDEIEAIRLIDPVTGEILNSLSALR
CCCHHHHHHHHHHCCCCHHEEECCCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHHE
VYPARHFVTPEAQLERAILNIEQELEEQLALFRKEGKLLEAQRLEQRTRYDLEMLREVGY
EECHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
CNGIENYSRHLTGRKAGEPPACLVDYFKADDWLLVVDESHVTVPQIRGMYNGDRARKQVL
CCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHH
VDHGFRLPSALDNRPLKAEEFWAKVHQCIFVSATPGNWELEQSEAQFETRVEDGKTLKFY
HHCCCCCCHHHCCCCCCHHHHHHHHHHEEEEEECCCCCEECHHHHHHHHHCCCCCEEEEE
VQGSGRVIEQVIRPTGVVDPEVHVRPTAGQVDDLLGEIYLRLERSQLGPAERVIVTTLTK
ECCCCHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RMAEDLTEYLQERGIRVRYLHSEITSIERIEILQDFREGAFDVLVGVNLLREGLDLPEVS
HHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
LVAILDADKEGFLRAERSLIQMIGRAARNVRGMVVMYADTMTSSMARAIAETQRRREIQL
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHEEEE
QYNRQHNITPKPIVKKNSNAILSFLAISRKLNDPDLEKAFQAAQEIPLSEIPELIGQLEL
EECCCCCCCCCCCEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
KMKEAAKNLEFEEAAQLRDRIKKLRQRLLGHPQGI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEFQLVSPYQPTGDQPKAIAGLVKSISEGHRFQTLLGATGTGKTFTIAHTIQQVGRPTL
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEHHHHHHHHHCCCEE
VMAHNKTLAAQLCNELRELFPHNAVEYFISYYDYYQPEAYVPSTDTYIAKSSSINDEIDM
EEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHH
LRHSATRSLFERRDVIVVASVSCIYGLGMPEEYLKASIPFKVGQEINQRDVLRDLASIQY
HHHHHHHHHHHHCCEEEEEEHHHHHCCCCCHHHHHCCCCHHHHCCCCHHHHHHHHHHHHC
ERNDLELVRGRFRLKGDVLEIVPAYEDRVIRIEFFGDEIEAIRLIDPVTGEILNSLSALR
CCCHHHHHHHHHHCCCCHHEEECCCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHHE
VYPARHFVTPEAQLERAILNIEQELEEQLALFRKEGKLLEAQRLEQRTRYDLEMLREVGY
EECHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
CNGIENYSRHLTGRKAGEPPACLVDYFKADDWLLVVDESHVTVPQIRGMYNGDRARKQVL
CCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHH
VDHGFRLPSALDNRPLKAEEFWAKVHQCIFVSATPGNWELEQSEAQFETRVEDGKTLKFY
HHCCCCCCHHHCCCCCCHHHHHHHHHHEEEEEECCCCCEECHHHHHHHHHCCCCCEEEEE
VQGSGRVIEQVIRPTGVVDPEVHVRPTAGQVDDLLGEIYLRLERSQLGPAERVIVTTLTK
ECCCCHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RMAEDLTEYLQERGIRVRYLHSEITSIERIEILQDFREGAFDVLVGVNLLREGLDLPEVS
HHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
LVAILDADKEGFLRAERSLIQMIGRAARNVRGMVVMYADTMTSSMARAIAETQRRREIQL
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHEEEE
QYNRQHNITPKPIVKKNSNAILSFLAISRKLNDPDLEKAFQAAQEIPLSEIPELIGQLEL
EECCCCCCCCCCCEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
KMKEAAKNLEFEEAAQLRDRIKKLRQRLLGHPQGI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA