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The map label for this gene is ruvA [H]

Identifier: 86608038

GI number: 86608038

Start: 558347

End: 558961

Strand: Direct

Name: ruvA [H]

Synonym: CYB_0546

Alternate gene names: 86608038

Gene position: 558347-558961 (Clockwise)

Preceding gene: 86608035

Following gene: 86608039

Centisome position: 18.33

GC content: 62.76

Gene sequence:

>615_bases
ATGATCGCGTTTTTAAGCGGCCACCTTGTGGCCATCGAATGGGGAGAGCGCAGCAGCCTCACCGTTGAGGTGCAGGGGAT
CGGCTATCGCGTCAAGGCCCCAGGACGTTTTCTCAAGCAACTGCCCGCAGTGGGGGAGCCCGTCCGGGTGTTCACCCATT
TGGTGGTGCGAGAGACCGAGCTGGTGTTGTACGGGTTTGGCTCGCCAGCCGAGCGCGATTTGTTTGTGGAACTCATCAAA
GTCTCAGGGGTGGGGCCGGCTTTGGGCTTGGCCCTGCTGAATACCTTCGGCCTGCCGGAGCTGGTGCAGGCGGTGGTGAC
CGAAAATGTGCGCCTGCTCTCCCTCACGCCGGGGGTAGGCCATAAAACGGCCCAACGGCTGGCCTTGGAGCTGAAAACCA
AGCTGGCCCACTGGCGACAGGGGATGGGGGTTGCGGATCAACCCTTGGCCGGGGGGCCGCCCATGCCCATCCGAGAAGAG
GTGGAAATGGCCTTACTGGCCCTGGGCTACAGCACTCAGGAAATTCAGGCTGCCTTGCAAGCTCTGCCCACCCACCCCCG
CCCAACGGAAGACTGGCTGCGGGATGCCATCACCTACCTGAGCCAGCAGCCATGA

Upstream 100 bases:

>100_bases
CCTTGTAGGGAAGCAGCTTTTGGCAAGGACTTTAGATTGCTTGGCTGACTCTGGAGCTCCAGTCGAGCAGAGTATCCCAA
ACCCAGATTAAACTCGCAGC

Downstream 100 bases:

>100_bases
AGCACCGCCGCATTGCCATTCTGGGTGGAACCTTCAACCCTGTACACCACGGCCATTTGATCATGGCAGAACAAGCTCTT
TGGCAGTTTGACCTGGATCA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MIAFLSGHLVAIEWGERSSLTVEVQGIGYRVKAPGRFLKQLPAVGEPVRVFTHLVVRETELVLYGFGSPAERDLFVELIK
VSGVGPALGLALLNTFGLPELVQAVVTENVRLLSLTPGVGHKTAQRLALELKTKLAHWRQGMGVADQPLAGGPPMPIREE
VEMALLALGYSTQEIQAALQALPTHPRPTEDWLRDAITYLSQQP

Sequences:

>Translated_204_residues
MIAFLSGHLVAIEWGERSSLTVEVQGIGYRVKAPGRFLKQLPAVGEPVRVFTHLVVRETELVLYGFGSPAERDLFVELIK
VSGVGPALGLALLNTFGLPELVQAVVTENVRLLSLTPGVGHKTAQRLALELKTKLAHWRQGMGVADQPLAGGPPMPIREE
VEMALLALGYSTQEIQAALQALPTHPRPTEDWLRDAITYLSQQP
>Mature_204_residues
MIAFLSGHLVAIEWGERSSLTVEVQGIGYRVKAPGRFLKQLPAVGEPVRVFTHLVVRETELVLYGFGSPAERDLFVELIK
VSGVGPALGLALLNTFGLPELVQAVVTENVRLLSLTPGVGHKTAQRLALELKTKLAHWRQGMGVADQPLAGGPPMPIREE
VEMALLALGYSTQEIQAALQALPTHPRPTEDWLRDAITYLSQQP

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=182, Percent_Identity=39.5604395604396, Blast_Score=114, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22214; Mature: 22214

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAFLSGHLVAIEWGERSSLTVEVQGIGYRVKAPGRFLKQLPAVGEPVRVFTHLVVRETE
CEEEECCCEEEEEECCCCEEEEEEECCCEEEECCHHHHHHCCCCCCHHHHHHHHHHHCCE
LVLYGFGSPAERDLFVELIKVSGVGPALGLALLNTFGLPELVQAVVTENVRLLSLTPGVG
EEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCC
HKTAQRLALELKTKLAHWRQGMGVADQPLAGGPPMPIREEVEMALLALGYSTQEIQAALQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
ALPTHPRPTEDWLRDAITYLSQQP
HCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIAFLSGHLVAIEWGERSSLTVEVQGIGYRVKAPGRFLKQLPAVGEPVRVFTHLVVRETE
CEEEECCCEEEEEECCCCEEEEEEECCCEEEECCHHHHHHCCCCCCHHHHHHHHHHHCCE
LVLYGFGSPAERDLFVELIKVSGVGPALGLALLNTFGLPELVQAVVTENVRLLSLTPGVG
EEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCC
HKTAQRLALELKTKLAHWRQGMGVADQPLAGGPPMPIREEVEMALLALGYSTQEIQAALQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
ALPTHPRPTEDWLRDAITYLSQQP
HCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA