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The map label for this gene is sir [H]

Identifier: 86607681

GI number: 86607681

Start: 192245

End: 194026

Strand: Reverse

Name: sir [H]

Synonym: CYB_0180

Alternate gene names: 86607681

Gene position: 194026-192245 (Counterclockwise)

Preceding gene: 86607682

Following gene: 86607679

Centisome position: 6.37

GC content: 60.27

Gene sequence:

>1782_bases
ATGCCCCCCATGATCCCATCCGAGGCCAAGCGTTCCAAGGTGGAGCAGATCAAGGCAGACAGCCACTTTCTACGGGATCC
CCTTCAGCAGGAGCTGGCCCAAGACACCACCCATTTCAGCGAGGCGGCGGTGCAGGTGCTCAAGTTCCATGGCGCCTACC
AGCAGGATGACCGGGATCGGCGGCAGCAACGGAAGCAGGAAGGATTGGAGCGGGCCTATTCCATCATGTTGCGCACCCGC
ATCCCAGGGGGACACGTGCCCCCCCAGCTTTACTTGACCCTGGATCGGCTGGCCGATGAGTACGGCAATGGCACCCTGCG
AGCCACAACGCGGCAAACCTTTCAGTTGCATGGGATCCTCAAGAAAAACCTCAAGGCCACCATAGCCAGCATTCTCAAAC
AGATGGGATCCACCCTGGCCGCCTGCGGCGATGTCAACCGCAACGTGATGGCACCGGTTGCCCCCTACAAAAATCGCCCT
GCCTATCGCTATGCCCAAGAGTATGCCCGCAAGCTGGCGGATCTGTTGGCTCCGAAGACCTCTGCCTACTACGAGATCTG
GGTGGATGGGGAGCCGGTTCCCATCCCACCGGTGGATGAGGAAGTGGTGGAAGCCGAGAAGTTTGTCGGCAACGGGGTGA
GGTTAGAGGGCCCAGAACCCCTGTATGGCCCCGTCTATTTGCCCCGCAAGTTTAAAACCGCCATCGCCGTAGCCGGGGAA
AACACGGTAGATGTGTACTCCCAGGACTTGGGCTTGATTGTGCTCACGGATCGCAAGGGCAACTTGAAGGGCTTCAACAT
TGTGGTGGGTGGGGGCATGGGGCGTACCCACGGCAAGGAAGAAACCCAGCCCCTTTTGGCCCAAAAGCTCTGCTTTGCCC
CGCCGGAATCGGTGTATCGGGTTTGCCAAGCGGTTTTGGCGGTACAGCGGGACTACGGCAACCGGCACGACCGCAAGCAG
GCGCGGTTGAAATACTTGGTGAGAGACTGGGGGATCCGCAAGTTTCGCCGTGTGGTCGAGCAGTACCTGGGGGAGAAGTT
GTTGCCCTTCCGGCGCATGCCCAAGTTTGTCCCCAACAGCGACGACTACCTAGGCTGGCACGAGCAGGGGGATGGCCGTT
GGTTTTTGGGCATCTCCATTGAAAATGGCCGCATCCAGGACACCCCAGAGCGGCAGCTCAAAACGGCGCTGCGCCGGATT
GTGGAAGCCTTTTCTCTGCACGTGCGGCTGACCCCCACTCAGGATTTACTTTTCATCGACATTGCGGAGCAGCAGCGGGA
TGCCATCAACCAGATCCTCAAATCCCACGGGGTGCTTTCCAAGGAAGAGATCCCCCAACTGGTGCGGCTGTCGATGGCCT
GCCCTGCCCTGCCCACCTGTGGGTTGGCGATTACCGAGTCGGAGCGGGCTTTGCCGGGGCTGGTTCGCCAGTTGGATCGG
CTGTTGCAGGAGCTGGATCTGCAGGATTCGCCCTTTTTGGTGCGCATGACCGGCTGCCCCAACGGCTGTGCCCGACCCTA
CTTGGCGGAACTGGGATTGGTGGGATCCGCCCCCAATGGCTACTACCAGATTTGGCTGGGAGCCAGCCCGCAGGGGGATC
GCCTGGCGCAAGTGTTTCAGGATCGGGTACACATCAGCCAGATCGTGCCGCTGATGAGAGTTCTCCTGCAGGTCTACAAG
CAGGAGCGCCGTCCTGGCGAGAGCTTCGGCGACTACTGCCACCGGATGGGGATCCCCTATTTGCAGGCCCAAGTTCAGCA
AAGGGATGGCGTTTTTGCCTGA

Upstream 100 bases:

>100_bases
AAACCCGGATAAGAGGCTGACTTTTCCAACTGGACGCTCTTCAAAGGAGGTGATAGCCTGTTATTCACAAGTATTCCGAC
CGGTTTACTGGAGATTATCA

Downstream 100 bases:

>100_bases
AGGGATCCCTCAAAAACGAGACCAAGCCTGTAGCCATTCCCGGAGCGCTTCCAGCCATCCAAGCGGTTCAGGCTTGGTTG
CTTCTGGAGCTTGCTCCTCG

Product: sulfite reductase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MPPMIPSEAKRSKVEQIKADSHFLRDPLQQELAQDTTHFSEAAVQVLKFHGAYQQDDRDRRQQRKQEGLERAYSIMLRTR
IPGGHVPPQLYLTLDRLADEYGNGTLRATTRQTFQLHGILKKNLKATIASILKQMGSTLAACGDVNRNVMAPVAPYKNRP
AYRYAQEYARKLADLLAPKTSAYYEIWVDGEPVPIPPVDEEVVEAEKFVGNGVRLEGPEPLYGPVYLPRKFKTAIAVAGE
NTVDVYSQDLGLIVLTDRKGNLKGFNIVVGGGMGRTHGKEETQPLLAQKLCFAPPESVYRVCQAVLAVQRDYGNRHDRKQ
ARLKYLVRDWGIRKFRRVVEQYLGEKLLPFRRMPKFVPNSDDYLGWHEQGDGRWFLGISIENGRIQDTPERQLKTALRRI
VEAFSLHVRLTPTQDLLFIDIAEQQRDAINQILKSHGVLSKEEIPQLVRLSMACPALPTCGLAITESERALPGLVRQLDR
LLQELDLQDSPFLVRMTGCPNGCARPYLAELGLVGSAPNGYYQIWLGASPQGDRLAQVFQDRVHISQIVPLMRVLLQVYK
QERRPGESFGDYCHRMGIPYLQAQVQQRDGVFA

Sequences:

>Translated_593_residues
MPPMIPSEAKRSKVEQIKADSHFLRDPLQQELAQDTTHFSEAAVQVLKFHGAYQQDDRDRRQQRKQEGLERAYSIMLRTR
IPGGHVPPQLYLTLDRLADEYGNGTLRATTRQTFQLHGILKKNLKATIASILKQMGSTLAACGDVNRNVMAPVAPYKNRP
AYRYAQEYARKLADLLAPKTSAYYEIWVDGEPVPIPPVDEEVVEAEKFVGNGVRLEGPEPLYGPVYLPRKFKTAIAVAGE
NTVDVYSQDLGLIVLTDRKGNLKGFNIVVGGGMGRTHGKEETQPLLAQKLCFAPPESVYRVCQAVLAVQRDYGNRHDRKQ
ARLKYLVRDWGIRKFRRVVEQYLGEKLLPFRRMPKFVPNSDDYLGWHEQGDGRWFLGISIENGRIQDTPERQLKTALRRI
VEAFSLHVRLTPTQDLLFIDIAEQQRDAINQILKSHGVLSKEEIPQLVRLSMACPALPTCGLAITESERALPGLVRQLDR
LLQELDLQDSPFLVRMTGCPNGCARPYLAELGLVGSAPNGYYQIWLGASPQGDRLAQVFQDRVHISQIVPLMRVLLQVYK
QERRPGESFGDYCHRMGIPYLQAQVQQRDGVFA
>Mature_592_residues
PPMIPSEAKRSKVEQIKADSHFLRDPLQQELAQDTTHFSEAAVQVLKFHGAYQQDDRDRRQQRKQEGLERAYSIMLRTRI
PGGHVPPQLYLTLDRLADEYGNGTLRATTRQTFQLHGILKKNLKATIASILKQMGSTLAACGDVNRNVMAPVAPYKNRPA
YRYAQEYARKLADLLAPKTSAYYEIWVDGEPVPIPPVDEEVVEAEKFVGNGVRLEGPEPLYGPVYLPRKFKTAIAVAGEN
TVDVYSQDLGLIVLTDRKGNLKGFNIVVGGGMGRTHGKEETQPLLAQKLCFAPPESVYRVCQAVLAVQRDYGNRHDRKQA
RLKYLVRDWGIRKFRRVVEQYLGEKLLPFRRMPKFVPNSDDYLGWHEQGDGRWFLGISIENGRIQDTPERQLKTALRRIV
EAFSLHVRLTPTQDLLFIDIAEQQRDAINQILKSHGVLSKEEIPQLVRLSMACPALPTCGLAITESERALPGLVRQLDRL
LQELDLQDSPFLVRMTGCPNGCARPYLAELGLVGSAPNGYYQIWLGASPQGDRLAQVFQDRVHISQIVPLMRVLLQVYKQ
ERRPGESFGDYCHRMGIPYLQAQVQQRDGVFA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Escherichia coli, GI1789122, Length=574, Percent_Identity=37.2822299651568, Blast_Score=381, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6322597, Length=589, Percent_Identity=42.2750424448217, Blast_Score=449, Evalue=1e-127,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066
- InterPro:   IPR011787 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 67116; Mature: 66985

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00365 NIR_SIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPMIPSEAKRSKVEQIKADSHFLRDPLQQELAQDTTHFSEAAVQVLKFHGAYQQDDRDR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RQQRKQEGLERAYSIMLRTRIPGGHVPPQLYLTLDRLADEYGNGTLRATTRQTFQLHGIL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHH
KKNLKATIASILKQMGSTLAACGDVNRNVMAPVAPYKNRPAYRYAQEYARKLADLLAPKT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
SAYYEIWVDGEPVPIPPVDEEVVEAEKFVGNGVRLEGPEPLYGPVYLPRKFKTAIAVAGE
CCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHEEECCC
NTVDVYSQDLGLIVLTDRKGNLKGFNIVVGGGMGRTHGKEETQPLLAQKLCFAPPESVYR
CCHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
VCQAVLAVQRDYGNRHDRKQARLKYLVRDWGIRKFRRVVEQYLGEKLLPFRRMPKFVPNS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHCCCHHHCCCCCCCC
DDYLGWHEQGDGRWFLGISIENGRIQDTPERQLKTALRRIVEAFSLHVRLTPTQDLLFID
CCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEE
IAEQQRDAINQILKSHGVLSKEEIPQLVRLSMACPALPTCGLAITESERALPGLVRQLDR
EHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHH
LLQELDLQDSPFLVRMTGCPNGCARPYLAELGLVGSAPNGYYQIWLGASPQGDRLAQVFQ
HHHHCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHH
DRVHISQIVPLMRVLLQVYKQERRPGESFGDYCHRMGIPYLQAQVQQRDGVFA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PPMIPSEAKRSKVEQIKADSHFLRDPLQQELAQDTTHFSEAAVQVLKFHGAYQQDDRDR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RQQRKQEGLERAYSIMLRTRIPGGHVPPQLYLTLDRLADEYGNGTLRATTRQTFQLHGIL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHH
KKNLKATIASILKQMGSTLAACGDVNRNVMAPVAPYKNRPAYRYAQEYARKLADLLAPKT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
SAYYEIWVDGEPVPIPPVDEEVVEAEKFVGNGVRLEGPEPLYGPVYLPRKFKTAIAVAGE
CCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHEEECCC
NTVDVYSQDLGLIVLTDRKGNLKGFNIVVGGGMGRTHGKEETQPLLAQKLCFAPPESVYR
CCHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
VCQAVLAVQRDYGNRHDRKQARLKYLVRDWGIRKFRRVVEQYLGEKLLPFRRMPKFVPNS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHCCCHHHCCCCCCCC
DDYLGWHEQGDGRWFLGISIENGRIQDTPERQLKTALRRIVEAFSLHVRLTPTQDLLFID
CCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEE
IAEQQRDAINQILKSHGVLSKEEIPQLVRLSMACPALPTCGLAITESERALPGLVRQLDR
EHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHH
LLQELDLQDSPFLVRMTGCPNGCARPYLAELGLVGSAPNGYYQIWLGASPQGDRLAQVFQ
HHHHCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHH
DRVHISQIVPLMRVLLQVYKQERRPGESFGDYCHRMGIPYLQAQVQQRDGVFA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8347657 [H]