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The map label for this gene is nucH [H]

Identifier: 86607611

GI number: 86607611

Start: 124060

End: 124593

Strand: Reverse

Name: nucH [H]

Synonym: CYB_0109

Alternate gene names: 86607611

Gene position: 124593-124060 (Counterclockwise)

Preceding gene: 86607612

Following gene: 86607610

Centisome position: 4.09

GC content: 57.87

Gene sequence:

>534_bases
ATGTTCCAGCGTATTGCTCTCGGCTCTGCTGCATTGGGATTGCTTCTGGCCATACCCGTCCTTCCCAGCCACGGGTTTGG
AGAGCCCCGGGTCGTTCCCGATACCCCGTTCTACTTCGACAACCACCGCTTCGATCGCTACCCAGATGCGGTTGTGGTGC
GGGTGGTCAACGGCGACACCCTAGTGGTGCAAATCGAAGGGGAACAGAAGATGCGCCTGATCCGGTTGGCCGGGATCGAG
GGTCTCAGCCCGGAAGAAAACCCCTATTACCAGCAAGCCATTGAACTGATGCGGGAGCGCATCCTCTACCGCACCGTCAA
GCTGGAAGGGGATAAGTTGCTGCGCAACGTAGATGCTACGGGCTTGGTGGAGGCCTATGTCTGGTTAGAAGGCCATCAGA
TGAACGCCATGTTGGTGCGCAATGGCCTGGCCCGCATCATCCCCTACAGCCACAACATCAAGTACGACAGCTACTACGGT
GGCCTACAAGAAAAAGCCCAGCAGGAGCGCCTTGGCATTTGGAGCCGTCTCTGA

Upstream 100 bases:

>100_bases
CTGGAGAGTTGCCGCTACCATTACACTTTGAGCGTTGCCACCGGAAACTCCCCGGCGGGAAAAGAAGAGGGGGCTGCGTC
CAAAGTGGGGAATTAAGGTC

Downstream 100 bases:

>100_bases
GTTGGCTTTATACTGAACTTCAGTTCTTTAATCTTCAAGGGAGCAGAGAGGAAAGAGCATGACTCTAGTCAATAATAAGC
TCAACTATACTGAAAATAAT

Product: thermonuclease

Products: NA

Alternate protein names: TNase; Micrococcal nuclease; Staphylococcal nuclease [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MFQRIALGSAALGLLLAIPVLPSHGFGEPRVVPDTPFYFDNHRFDRYPDAVVVRVVNGDTLVVQIEGEQKMRLIRLAGIE
GLSPEENPYYQQAIELMRERILYRTVKLEGDKLLRNVDATGLVEAYVWLEGHQMNAMLVRNGLARIIPYSHNIKYDSYYG
GLQEKAQQERLGIWSRL

Sequences:

>Translated_177_residues
MFQRIALGSAALGLLLAIPVLPSHGFGEPRVVPDTPFYFDNHRFDRYPDAVVVRVVNGDTLVVQIEGEQKMRLIRLAGIE
GLSPEENPYYQQAIELMRERILYRTVKLEGDKLLRNVDATGLVEAYVWLEGHQMNAMLVRNGLARIIPYSHNIKYDSYYG
GLQEKAQQERLGIWSRL
>Mature_177_residues
MFQRIALGSAALGLLLAIPVLPSHGFGEPRVVPDTPFYFDNHRFDRYPDAVVVRVVNGDTLVVQIEGEQKMRLIRLAGIE
GLSPEENPYYQQAIELMRERILYRTVKLEGDKLLRNVDATGLVEAYVWLEGHQMNAMLVRNGLARIIPYSHNIKYDSYYG
GLQEKAQQERLGIWSRL

Specific function: Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5'-position of the phosphodiester bond [H]

COG id: COG1525

COG function: function code L; Micrococcal nuclease (thermonuclease) homologs

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thermonuclease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016071
- InterPro:   IPR006021
- InterPro:   IPR002071 [H]

Pfam domain/function: PF00565 SNase [H]

EC number: =3.1.31.1 [H]

Molecular weight: Translated: 20229; Mature: 20229

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50830 TNASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQRIALGSAALGLLLAIPVLPSHGFGEPRVVPDTPFYFDNHRFDRYPDAVVVRVVNGDT
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCE
LVVQIEGEQKMRLIRLAGIEGLSPEENPYYQQAIELMRERILYRTVKLEGDKLLRNVDAT
EEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECHHHHHHHCCCC
GLVEAYVWLEGHQMNAMLVRNGLARIIPYSHNIKYDSYYGGLQEKAQQERLGIWSRL
HHEEEEEEEECCCCCHHHHHCCHHHCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFQRIALGSAALGLLLAIPVLPSHGFGEPRVVPDTPFYFDNHRFDRYPDAVVVRVVNGDT
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCE
LVVQIEGEQKMRLIRLAGIEGLSPEENPYYQQAIELMRERILYRTVKLEGDKLLRNVDAT
EEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECHHHHHHHCCCC
GLVEAYVWLEGHQMNAMLVRNGLARIIPYSHNIKYDSYYGGLQEKAQQERLGIWSRL
HHEEEEEEEECCCCCHHHHHCCHHHCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045422 [H]