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The map label for this gene is 86607562

Identifier: 86607562

GI number: 86607562

Start: 72316

End: 73227

Strand: Reverse

Name: 86607562

Synonym: CYB_0059

Alternate gene names: NA

Gene position: 73227-72316 (Counterclockwise)

Preceding gene: 86607563

Following gene: 86607556

Centisome position: 2.4

GC content: 61.4

Gene sequence:

>912_bases
ATGTTGCCTGTTTACTATTCCGATATTTTCCTCAGCCACGATACTGGGCCATTTCACCCCGAGCGTCCGGCTCGCTTGCA
GTCCATTGTTAAGGCGCTGCGTGGTGCCCCTTTTGCCAACCAGTTGGAATGGCGGGATCCCCCCTTGGCGGAGCTGGCAG
AGCTGGAGCGAGTACACTCGCGTCAGCACATCCAACAGGTGGCTGAGTTGGCAACAGCAGGTGGGGGACACATTGATGCC
GACACTGCTCTCTCGGAGAGAAGTTTTGAAGCGGCGCGCCTGGCTGTGGGGGCTTGGGTGGCCGGCTCTGCCTCGGTTTT
GACCACCGCTCAGCCGGCTTTGGTGCTGTGCCGTCCACCTGGGCATCACGCAGAGCCAGAACGGGCAATGGGGTTTTGTT
TATTCAGCAACGCAGCCATTGCGGCGCTGTGGGCGCTGGATCAGCCGGGGGTGAAGCGGGTGGCGATTTTCGATTGGGAT
GTTCACCACGGCAACGGCACGCAGGCGGTGGTGGAGCGCTATCCCCAACTGGCCTATGCCTCCATCCATCAGTTTCCCCT
CTACCCCGGCACCGGCTCCGCTCGCGAAACCGGGATCCACGGCAACCTCTGCAACGTGCCTTTGCCTGCCGGCTCGGATT
GGTTGGCCTACAAAAAGGCCCTCGACGAGAAGATCTTGCCGTTCTTGCAAGCGTTCCAGCCCGATTTGCTGCTGGTGAGC
GCCGGCTTCGACTGTGCCAAAGGGGATCCCTTGGCCGGTATGCAGCTAGAGCCGGAAGCCTTTGGCCGCATGGCCCGCCT
TTGCCTGGAGCAGGTGACCCGCAAAACCCTCTTCGGCTTGGAAGGCGGCTATAACCTGGACAACCTGGCGCGCGGCTGGC
TGAGCCTGGCCCAAGCTTGCCTGGAGAGTTAA

Upstream 100 bases:

>100_bases
TGACCCCTATGCGGGATCCATGTCAGAGGTCTTCTACGGATAGAGGGGGCGGGCTTAAGCTACACTGCAAAGGCGTTGCC
TTAGCTTGTTGCCTCTGCCC

Downstream 100 bases:

>100_bases
CCTTTCCACTTCACCTTGGGTAAAATCTGCCGCACATCCACCCGATCCTTGTACTTGAGAGCAAAGTTGAGCAGCGAATC
CAAGAGGGAATCGGACAGAT

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MLPVYYSDIFLSHDTGPFHPERPARLQSIVKALRGAPFANQLEWRDPPLAELAELERVHSRQHIQQVAELATAGGGHIDA
DTALSERSFEAARLAVGAWVAGSASVLTTAQPALVLCRPPGHHAEPERAMGFCLFSNAAIAALWALDQPGVKRVAIFDWD
VHHGNGTQAVVERYPQLAYASIHQFPLYPGTGSARETGIHGNLCNVPLPAGSDWLAYKKALDEKILPFLQAFQPDLLLVS
AGFDCAKGDPLAGMQLEPEAFGRMARLCLEQVTRKTLFGLEGGYNLDNLARGWLSLAQACLES

Sequences:

>Translated_303_residues
MLPVYYSDIFLSHDTGPFHPERPARLQSIVKALRGAPFANQLEWRDPPLAELAELERVHSRQHIQQVAELATAGGGHIDA
DTALSERSFEAARLAVGAWVAGSASVLTTAQPALVLCRPPGHHAEPERAMGFCLFSNAAIAALWALDQPGVKRVAIFDWD
VHHGNGTQAVVERYPQLAYASIHQFPLYPGTGSARETGIHGNLCNVPLPAGSDWLAYKKALDEKILPFLQAFQPDLLLVS
AGFDCAKGDPLAGMQLEPEAFGRMARLCLEQVTRKTLFGLEGGYNLDNLARGWLSLAQACLES
>Mature_303_residues
MLPVYYSDIFLSHDTGPFHPERPARLQSIVKALRGAPFANQLEWRDPPLAELAELERVHSRQHIQQVAELATAGGGHIDA
DTALSERSFEAARLAVGAWVAGSASVLTTAQPALVLCRPPGHHAEPERAMGFCLFSNAAIAALWALDQPGVKRVAIFDWD
VHHGNGTQAVVERYPQLAYASIHQFPLYPGTGSARETGIHGNLCNVPLPAGSDWLAYKKALDEKILPFLQAFQPDLLLVS
AGFDCAKGDPLAGMQLEPEAFGRMARLCLEQVTRKTLFGLEGGYNLDNLARGWLSLAQACLES

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI17158039, Length=324, Percent_Identity=31.4814814814815, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI30795202, Length=324, Percent_Identity=31.4814814814815, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI30795204, Length=324, Percent_Identity=31.4814814814815, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI13128864, Length=304, Percent_Identity=34.5394736842105, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI148539870, Length=329, Percent_Identity=32.5227963525836, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI169234807, Length=329, Percent_Identity=32.5227963525836, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI20070354, Length=319, Percent_Identity=34.7962382445141, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI153085395, Length=323, Percent_Identity=32.5077399380805, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI62750349, Length=324, Percent_Identity=31.4814814814815, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI62750347, Length=324, Percent_Identity=31.4814814814815, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI226529806, Length=311, Percent_Identity=30.8681672025724, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI8923769, Length=317, Percent_Identity=25.8675078864353, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI13128860, Length=316, Percent_Identity=26.2658227848101, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI293336691, Length=303, Percent_Identity=25.0825082508251, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI262073088, Length=185, Percent_Identity=27.5675675675676, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI13128862, Length=306, Percent_Identity=26.4705882352941, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI209862883, Length=167, Percent_Identity=25.748502994012, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI262073092, Length=250, Percent_Identity=24.4, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI217272877, Length=167, Percent_Identity=25.748502994012, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193209491, Length=319, Percent_Identity=35.423197492163, Blast_Score=158, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17540334, Length=306, Percent_Identity=32.6797385620915, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17540332, Length=306, Percent_Identity=32.6797385620915, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI193206283, Length=306, Percent_Identity=32.6797385620915, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17537347, Length=287, Percent_Identity=35.8885017421603, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI25154020, Length=294, Percent_Identity=30.952380952381, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25154022, Length=294, Percent_Identity=30.2721088435374, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17508561, Length=306, Percent_Identity=24.5098039215686, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17534739, Length=303, Percent_Identity=25.4125412541254, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17561978, Length=306, Percent_Identity=25.1633986928105, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324307, Length=334, Percent_Identity=34.1317365269461, Blast_Score=170, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323999, Length=319, Percent_Identity=23.1974921630094, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325325, Length=168, Percent_Identity=29.7619047619048, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6321244, Length=299, Percent_Identity=23.4113712374582, Blast_Score=79, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6325141, Length=139, Percent_Identity=28.7769784172662, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281360899, Length=300, Percent_Identity=36.6666666666667, Blast_Score=171, Evalue=7e-43,
Organism=Drosophila melanogaster, GI24642146, Length=300, Percent_Identity=36.6666666666667, Blast_Score=170, Evalue=9e-43,
Organism=Drosophila melanogaster, GI24642142, Length=300, Percent_Identity=36.6666666666667, Blast_Score=170, Evalue=9e-43,
Organism=Drosophila melanogaster, GI24642144, Length=300, Percent_Identity=36.6666666666667, Blast_Score=170, Evalue=9e-43,
Organism=Drosophila melanogaster, GI281360801, Length=309, Percent_Identity=35.2750809061489, Blast_Score=147, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24641720, Length=309, Percent_Identity=35.2750809061489, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI281360799, Length=309, Percent_Identity=35.2750809061489, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24657891, Length=305, Percent_Identity=25.5737704918033, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24644244, Length=307, Percent_Identity=25.4071661237785, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 32909; Mature: 32909

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVYYSDIFLSHDTGPFHPERPARLQSIVKALRGAPFANQLEWRDPPLAELAELERVHS
CCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
RQHIQQVAELATAGGGHIDADTALSERSFEAARLAVGAWVAGSASVLTTAQPALVLCRPP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCC
GHHAEPERAMGFCLFSNAAIAALWALDQPGVKRVAIFDWDVHHGNGTQAVVERYPQLAYA
CCCCCHHHHHEEHEECCCHHHHHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHH
SIHQFPLYPGTGSARETGIHGNLCNVPLPAGSDWLAYKKALDEKILPFLQAFQPDLLLVS
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGFDCAKGDPLAGMQLEPEAFGRMARLCLEQVTRKTLFGLEGGYNLDNLARGWLSLAQAC
CCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LES
HCC
>Mature Secondary Structure
MLPVYYSDIFLSHDTGPFHPERPARLQSIVKALRGAPFANQLEWRDPPLAELAELERVHS
CCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
RQHIQQVAELATAGGGHIDADTALSERSFEAARLAVGAWVAGSASVLTTAQPALVLCRPP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCC
GHHAEPERAMGFCLFSNAAIAALWALDQPGVKRVAIFDWDVHHGNGTQAVVERYPQLAYA
CCCCCHHHHHEEHEECCCHHHHHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHH
SIHQFPLYPGTGSARETGIHGNLCNVPLPAGSDWLAYKKALDEKILPFLQAFQPDLLLVS
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGFDCAKGDPLAGMQLEPEAFGRMARLCLEQVTRKTLFGLEGGYNLDNLARGWLSLAQAC
CCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LES
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]