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The map label for this gene is zraS [C]

Identifier: 86360994

GI number: 86360994

Start: 282999

End: 284672

Strand: Reverse

Name: zraS [C]

Synonym: RHE_PF00264

Alternate gene names: 86360994

Gene position: 284672-282999 (Counterclockwise)

Preceding gene: 86360995

Following gene: 86360993

Centisome position: 44.31

GC content: 64.28

Gene sequence:

>1674_bases
ATGAACCCCGTCAACATCCTCCTCGTCGACGACCAGCCCGCGAAGCTCCTGAGCTACGAAGTTATTCTCGAAGAGCTCGA
GGAAAACCTGATCAAGGCGCAATCGGCGCGCGAAGCTTTCGAACATCTGCTGCGAAGCGAGATCGCCGTGATCCTCGTCG
ACGTCTGCATGCCGGAACAGGACGGTTTCGAACTCGTCGGCATGATCCGGCAGCACCCGCGCTATCAGAACACGCCGATC
ATTTTCGTCTCCGCCGTGATGCTGGCCGAACCCGACCGGCTGCGCGGCTATGCGGTCGGCGCCGTCGACTACGTCTCCGT
CCCGATCGTGCCTGAGGTGTTGAGGGCCAAAGTCAGGGTTTTTGCCGATCTCTACAGGAAGACGCGAGAACTCGAACGTC
TGAATGCCGAACTGGAGGCGAGGGTGCACCAGCGCACCGCCGAGCTCGAAGCGTCGGCGGCGCAGTTGCGCCAGCTGAAC
GAGGAGCTCGAGCACCGCATCGACCAAAGGACGCGCGAGCGTGAGGAGGCGCTGGCGCAGCTCTTCGAGGCGCAGAAGCT
CGATACGATCGGCCACCTGACAGGCGGCGTCGCGCACGATTTCAACAATCTTCTCATGGCGGTGCTCGGCAGCCTCAGTC
TGCTAAAGAAGCGGCTTCCGGCGGATGAGCGAAGCGAACGCCTGGTGACGAACGCCATCCAGGCGGCCGAACGCGGGACG
GCGCTCACCCAGCGCCTGCTTGCCTTCGCTCGCCGACAGGAGCTGAAGCCGCAGGCGGTCGACTTTCTCCGGCTGTTCGA
AAACGTCGAGGATCTGCTCGCCAAGGCGGTCGGACCGCGGGTCGAGATCCGCAAGCGCATCCCAGCGGATCTGGAACCAC
TGCTGGTGGACAGCAATCAGCTGGAACTGGCGCTCCTCAACCTCTTCGTCAATGCGCGGGATGCGCTCGAAAGCGGCGGT
GCAGTGACCGTCGCGGCTGCGGCGGAAGAGGTTCGGCCGGCCGGTCTTGCAGGCGGGAATTACATCAGGATATCGGTCTC
GGATGACGGCGAAGGGATGGACGAAGCGACGGTTCTGCGCGCCGCCGAGCCATTCTTCACCACGAAGGGAATCGGCAAGG
GCACCGGGCTCGGCCTGTCGATGGTGCACGGCCTGGCAGCGCAATCGGGCGGTTCGATCCAGATTTCGAGCACGAGAGGT
AAGGGCACGACCGTCTCCCTCTGGCTGCCGGTCGCGCAGAGCATTGCCAAGGCGCAGCCGGCGGTCGTGCCTGCGGACGT
GGAACCCCTGAAATCGGTCTCGCGATCGCTTGCCATCCTCGTCGTCGACGACGATGCCCTCGTCAGGACTGGGACCGTGG
CAATGCTGGAGGATCTCGGACACCTGCCGCGGGAGGCGGCTTCCGCTACTCAGGCCCTGGAATTCCTCGCCGGCGGGCAG
AAGTGTGATCTCGTCATCACCGATCATGCCATGCCGGGCATGACCGGCGCCGAGCTCGCGCGCCACCTTCGTTCAGCCTT
CCCCAACCTGCCCGTGATCCTCGCCTCAGGCTATGTCGAGCTTGCCGAGGATCAGGGGCTCGGCCGGATGCTCAGGATGG
CGAAGCCGTTCACGCAAGAGCAGCTCCAAGCGGCCATGGACGAGGCGCTGAGGAACAAGGTCGCGGCAGCGTGA

Upstream 100 bases:

>100_bases
TGCCTGGAGGCGGGTGCGTCGGATTACCTGGCGAAGCCCGTCAACACCGAGCAGCTCCTGTCGGCTCTGCGCATGTGGTT
GCACCGCTGAGGATCCGGCC

Downstream 100 bases:

>100_bases
TGGGGCTGGAAAGGGCGGCTGCGACAATGGCGCGATATTGGCGCGGGCAGGCCACATGGATCGGCTGGGATATCTTCGAA
ATCTGACATCGCGGCGAGGG

Product: two-component sensor histidine kinase/response regulator hybrid protein

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MNPVNILLVDDQPAKLLSYEVILEELEENLIKAQSAREAFEHLLRSEIAVILVDVCMPEQDGFELVGMIRQHPRYQNTPI
IFVSAVMLAEPDRLRGYAVGAVDYVSVPIVPEVLRAKVRVFADLYRKTRELERLNAELEARVHQRTAELEASAAQLRQLN
EELEHRIDQRTREREEALAQLFEAQKLDTIGHLTGGVAHDFNNLLMAVLGSLSLLKKRLPADERSERLVTNAIQAAERGT
ALTQRLLAFARRQELKPQAVDFLRLFENVEDLLAKAVGPRVEIRKRIPADLEPLLVDSNQLELALLNLFVNARDALESGG
AVTVAAAAEEVRPAGLAGGNYIRISVSDDGEGMDEATVLRAAEPFFTTKGIGKGTGLGLSMVHGLAAQSGGSIQISSTRG
KGTTVSLWLPVAQSIAKAQPAVVPADVEPLKSVSRSLAILVVDDDALVRTGTVAMLEDLGHLPREAASATQALEFLAGGQ
KCDLVITDHAMPGMTGAELARHLRSAFPNLPVILASGYVELAEDQGLGRMLRMAKPFTQEQLQAAMDEALRNKVAAA

Sequences:

>Translated_557_residues
MNPVNILLVDDQPAKLLSYEVILEELEENLIKAQSAREAFEHLLRSEIAVILVDVCMPEQDGFELVGMIRQHPRYQNTPI
IFVSAVMLAEPDRLRGYAVGAVDYVSVPIVPEVLRAKVRVFADLYRKTRELERLNAELEARVHQRTAELEASAAQLRQLN
EELEHRIDQRTREREEALAQLFEAQKLDTIGHLTGGVAHDFNNLLMAVLGSLSLLKKRLPADERSERLVTNAIQAAERGT
ALTQRLLAFARRQELKPQAVDFLRLFENVEDLLAKAVGPRVEIRKRIPADLEPLLVDSNQLELALLNLFVNARDALESGG
AVTVAAAAEEVRPAGLAGGNYIRISVSDDGEGMDEATVLRAAEPFFTTKGIGKGTGLGLSMVHGLAAQSGGSIQISSTRG
KGTTVSLWLPVAQSIAKAQPAVVPADVEPLKSVSRSLAILVVDDDALVRTGTVAMLEDLGHLPREAASATQALEFLAGGQ
KCDLVITDHAMPGMTGAELARHLRSAFPNLPVILASGYVELAEDQGLGRMLRMAKPFTQEQLQAAMDEALRNKVAAA
>Mature_557_residues
MNPVNILLVDDQPAKLLSYEVILEELEENLIKAQSAREAFEHLLRSEIAVILVDVCMPEQDGFELVGMIRQHPRYQNTPI
IFVSAVMLAEPDRLRGYAVGAVDYVSVPIVPEVLRAKVRVFADLYRKTRELERLNAELEARVHQRTAELEASAAQLRQLN
EELEHRIDQRTREREEALAQLFEAQKLDTIGHLTGGVAHDFNNLLMAVLGSLSLLKKRLPADERSERLVTNAIQAAERGT
ALTQRLLAFARRQELKPQAVDFLRLFENVEDLLAKAVGPRVEIRKRIPADLEPLLVDSNQLELALLNLFVNARDALESGG
AVTVAAAAEEVRPAGLAGGNYIRISVSDDGEGMDEATVLRAAEPFFTTKGIGKGTGLGLSMVHGLAAQSGGSIQISSTRG
KGTTVSLWLPVAQSIAKAQPAVVPADVEPLKSVSRSLAILVVDDDALVRTGTVAMLEDLGHLPREAASATQALEFLAGGQ
KCDLVITDHAMPGMTGAELARHLRSAFPNLPVILASGYVELAEDQGLGRMLRMAKPFTQEQLQAAMDEALRNKVAAA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=251, Percent_Identity=33.4661354581673, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1788549, Length=270, Percent_Identity=27.7777777777778, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI48994928, Length=368, Percent_Identity=28.5326086956522, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788713, Length=369, Percent_Identity=26.2872628726287, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=181, Percent_Identity=30.939226519337, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60621; Mature: 60621

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVNILLVDDQPAKLLSYEVILEELEENLIKAQSAREAFEHLLRSEIAVILVDVCMPEQ
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DGFELVGMIRQHPRYQNTPIIFVSAVMLAEPDRLRGYAVGAVDYVSVPIVPEVLRAKVRV
CCHHHHHHHHHCCCCCCCCEEEEEHHHHCCCHHHCCEEECCHHHEECCCHHHHHHHHHHH
FADLYRKTRELERLNAELEARVHQRTAELEASAAQLRQLNEELEHRIDQRTREREEALAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFEAQKLDTIGHLTGGVAHDFNNLLMAVLGSLSLLKKRLPADERSERLVTNAIQAAERGT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ALTQRLLAFARRQELKPQAVDFLRLFENVEDLLAKAVGPRVEIRKRIPADLEPLLVDSNQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEECCCC
LELALLNLFVNARDALESGGAVTVAAAAEEVRPAGLAGGNYIRISVSDDGEGMDEATVLR
HHHHHHHHHHHHHHHHHCCCCEEEEECHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHH
AAEPFFTTKGIGKGTGLGLSMVHGLAAQSGGSIQISSTRGKGTTVSLWLPVAQSIAKAQP
HCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEHHHHHHHHHCCC
AVVPADVEPLKSVSRSLAILVVDDDALVRTGTVAMLEDLGHLPREAASATQALEFLAGGQ
CCCCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
KCDLVITDHAMPGMTGAELARHLRSAFPNLPVILASGYVELAEDQGLGRMLRMAKPFTQE
EEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCHHHHHHHHCCCCHH
QLQAAMDEALRNKVAAA
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPVNILLVDDQPAKLLSYEVILEELEENLIKAQSAREAFEHLLRSEIAVILVDVCMPEQ
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DGFELVGMIRQHPRYQNTPIIFVSAVMLAEPDRLRGYAVGAVDYVSVPIVPEVLRAKVRV
CCHHHHHHHHHCCCCCCCCEEEEEHHHHCCCHHHCCEEECCHHHEECCCHHHHHHHHHHH
FADLYRKTRELERLNAELEARVHQRTAELEASAAQLRQLNEELEHRIDQRTREREEALAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFEAQKLDTIGHLTGGVAHDFNNLLMAVLGSLSLLKKRLPADERSERLVTNAIQAAERGT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ALTQRLLAFARRQELKPQAVDFLRLFENVEDLLAKAVGPRVEIRKRIPADLEPLLVDSNQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEECCCC
LELALLNLFVNARDALESGGAVTVAAAAEEVRPAGLAGGNYIRISVSDDGEGMDEATVLR
HHHHHHHHHHHHHHHHHCCCCEEEEECHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHH
AAEPFFTTKGIGKGTGLGLSMVHGLAAQSGGSIQISSTRGKGTTVSLWLPVAQSIAKAQP
HCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEHHHHHHHHHCCC
AVVPADVEPLKSVSRSLAILVVDDDALVRTGTVAMLEDLGHLPREAASATQALEFLAGGQ
CCCCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
KCDLVITDHAMPGMTGAELARHLRSAFPNLPVILASGYVELAEDQGLGRMLRMAKPFTQE
EEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCHHHHHHHHCCCCHH
QLQAAMDEALRNKVAAA
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA