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The map label for this gene is dgoD1 [H]

Identifier: 86360960

GI number: 86360960

Start: 243309

End: 244496

Strand: Reverse

Name: dgoD1 [H]

Synonym: RHE_PF00230

Alternate gene names: 86360960

Gene position: 244496-243309 (Counterclockwise)

Preceding gene: 86360961

Following gene: 86360959

Centisome position: 38.05

GC content: 64.06

Gene sequence:

>1188_bases
ATGCACGCCGGTCAGCCCGACCCTTCGAAATGGGCTTCGGATGAGCGGTCGGGGGACGGGACATCCACGCAGCTGCGGGG
CACCAGGAATTGGTTGTTCTTGAAGATCGACACCGATGAGGGCATCACCGGCATCGGCGAATGCTCCGGCTGGCCGCGCG
TGATTGAAACGGCGATCAATGATCTGGCGCCGCTGCTGATCGGCGAAGATCCGGCTCATACCGAACGCCTGTGCCAGAAA
TTGCATATTGCGATGATGGGTCACGGCATGCTCGGCACGGTCGGTGGCGGCGCGATGACCGGCATCGACATGGCGCTTTG
GGACATCAAGGGCAAAGCGCTCGGCGTGCCTGTCTGGATGCTGCTCGGCGGCAAGGTGCGCGACAGGATCCCGATCTATT
CGCATGCCAATACGCCGGAACGTGCGCTTGCAGTCAAACAGCGCGGCATAAAGGCGATCAAGTGCGGTGGTGTGGCCGAT
CCGGTTCGCAAGGTCGCAGCACTGCGCGAGGCGGTCGGCGACGATATGGACATCGCCATCGACCTGCATGGGCCGCCATG
GCTGACCCCTGCGGACGCCTGCCGCCTGGTGCGGGCGCTCGAACCCTATGAGCTGATGTGGGTGGAAGATCCGATCGCGC
CCGACAATCTCGACGGCTACAAGCGCATTCGCGACGCCGCTGATGTGCCACTTGCCGCCGGCGAACGCTCGGCAACGATC
TTTGGCGAGCGCGAGCTCATCGAACGAGAGCTGGTCGATGTCATTCAGCCCGATACCGGCCGGGCCGGCGGCATCACCCA
AATGAAGAAGATCGCGGCCATGGCCGAAGCCCACCACGTCCAGATGGCACCGCATTCGGGCTCGCTCGGACCGGTGGCGG
AATATGCGGCACTGCATTTGCTTGCGGCTATTCCGAACGCGCTGATCCTCGAGCGGCTCGACGACGACTGGGACGGCCGT
CGCCGGACGATCGTGCCGCATCCCGAGCAGGTCGACGGGCTGATCACGGTGCCCGACGCCCCCGGGCTCGGCTGCGATAT
CGACGAGGAATTCGTCGGTCGGTTTCCAAGCGGCGGCAATGTCTCCGTTCCTGTGCCGGAGGCCGCCGACTCCTACAATC
CCGGAACCTACAACGAGCATCTCTACGTGCAGACGCGCGTGGCGCGCCGCAGCTATTTCAATCGCTAG

Upstream 100 bases:

>100_bases
GCGACCGCGATCATTCGCGGCGCTTCCGCTACGTCGCTCCCGATAATCTGAAGAACGGGAGCTCTCAGCGATGAAGATCA
CCGGCATCAGAACGTTTCTC

Downstream 100 bases:

>100_bases
AAGGACAGAATGATGAAGATCGACAGAATGCGAGTGTTCATGACCCGCGATAAGGACCGTCCCCGCGTGATCGTCGCACT
CGATACCGATGATGGGCTGA

Product: putative isomerase protein

Products: NA

Alternate protein names: GalD 1 [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MHAGQPDPSKWASDERSGDGTSTQLRGTRNWLFLKIDTDEGITGIGECSGWPRVIETAINDLAPLLIGEDPAHTERLCQK
LHIAMMGHGMLGTVGGGAMTGIDMALWDIKGKALGVPVWMLLGGKVRDRIPIYSHANTPERALAVKQRGIKAIKCGGVAD
PVRKVAALREAVGDDMDIAIDLHGPPWLTPADACRLVRALEPYELMWVEDPIAPDNLDGYKRIRDAADVPLAAGERSATI
FGERELIERELVDVIQPDTGRAGGITQMKKIAAMAEAHHVQMAPHSGSLGPVAEYAALHLLAAIPNALILERLDDDWDGR
RRTIVPHPEQVDGLITVPDAPGLGCDIDEEFVGRFPSGGNVSVPVPEAADSYNPGTYNEHLYVQTRVARRSYFNR

Sequences:

>Translated_395_residues
MHAGQPDPSKWASDERSGDGTSTQLRGTRNWLFLKIDTDEGITGIGECSGWPRVIETAINDLAPLLIGEDPAHTERLCQK
LHIAMMGHGMLGTVGGGAMTGIDMALWDIKGKALGVPVWMLLGGKVRDRIPIYSHANTPERALAVKQRGIKAIKCGGVAD
PVRKVAALREAVGDDMDIAIDLHGPPWLTPADACRLVRALEPYELMWVEDPIAPDNLDGYKRIRDAADVPLAAGERSATI
FGERELIERELVDVIQPDTGRAGGITQMKKIAAMAEAHHVQMAPHSGSLGPVAEYAALHLLAAIPNALILERLDDDWDGR
RRTIVPHPEQVDGLITVPDAPGLGCDIDEEFVGRFPSGGNVSVPVPEAADSYNPGTYNEHLYVQTRVARRSYFNR
>Mature_395_residues
MHAGQPDPSKWASDERSGDGTSTQLRGTRNWLFLKIDTDEGITGIGECSGWPRVIETAINDLAPLLIGEDPAHTERLCQK
LHIAMMGHGMLGTVGGGAMTGIDMALWDIKGKALGVPVWMLLGGKVRDRIPIYSHANTPERALAVKQRGIKAIKCGGVAD
PVRKVAALREAVGDDMDIAIDLHGPPWLTPADACRLVRALEPYELMWVEDPIAPDNLDGYKRIRDAADVPLAAGERSATI
FGERELIERELVDVIQPDTGRAGGITQMKKIAAMAEAHHVQMAPHSGSLGPVAEYAALHLLAAIPNALILERLDDDWDGR
RRTIVPHPEQVDGLITVPDAPGLGCDIDEEFVGRFPSGGNVSVPVPEAADSYNPGTYNEHLYVQTRVARRSYFNR

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=359, Percent_Identity=35.6545961002786, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1787864, Length=377, Percent_Identity=31.5649867374005, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI226510960, Length=365, Percent_Identity=28.2191780821918, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 42833; Mature: 42833

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAGQPDPSKWASDERSGDGTSTQLRGTRNWLFLKIDTDEGITGIGECSGWPRVIETAIN
CCCCCCCCHHHCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
DLAPLLIGEDPAHTERLCQKLHIAMMGHGMLGTVGGGAMTGIDMALWDIKGKALGVPVWM
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHEEEEEECCCCEECCCEEE
LLGGKVRDRIPIYSHANTPERALAVKQRGIKAIKCGGVADPVRKVAALREAVGDDMDIAI
HCCCCHHCCCCEEECCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEE
DLHGPPWLTPADACRLVRALEPYELMWVEDPIAPDNLDGYKRIRDAADVPLAAGERSATI
EECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCEEE
FGERELIERELVDVIQPDTGRAGGITQMKKIAAMAEAHHVQMAPHSGSLGPVAEYAALHL
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHH
LAAIPNALILERLDDDWDGRRRTIVPHPEQVDGLITVPDAPGLGCDIDEEFVGRFPSGGN
HHHCCHHHHHHHCCCCCCCCCCCCCCCCHHCCCEEECCCCCCCCCCCCHHHHCCCCCCCC
VSVPVPEAADSYNPGTYNEHLYVQTRVARRSYFNR
EEECCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCC
>Mature Secondary Structure
MHAGQPDPSKWASDERSGDGTSTQLRGTRNWLFLKIDTDEGITGIGECSGWPRVIETAIN
CCCCCCCCHHHCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
DLAPLLIGEDPAHTERLCQKLHIAMMGHGMLGTVGGGAMTGIDMALWDIKGKALGVPVWM
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHEEEEEECCCCEECCCEEE
LLGGKVRDRIPIYSHANTPERALAVKQRGIKAIKCGGVADPVRKVAALREAVGDDMDIAI
HCCCCHHCCCCEEECCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEE
DLHGPPWLTPADACRLVRALEPYELMWVEDPIAPDNLDGYKRIRDAADVPLAAGERSATI
EECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCEEE
FGERELIERELVDVIQPDTGRAGGITQMKKIAAMAEAHHVQMAPHSGSLGPVAEYAALHL
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHH
LAAIPNALILERLDDDWDGRRRTIVPHPEQVDGLITVPDAPGLGCDIDEEFVGRFPSGGN
HHHCCHHHHHHHCCCCCCCCCCCCCCCCHHCCCEEECCCCCCCCCCCCHHHHCCCCCCCC
VSVPVPEAADSYNPGTYNEHLYVQTRVARRSYFNR
EEECCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA