Click here to switch to the map view.

The map label for this gene is eutB

Identifier: 86360913

GI number: 86360913

Start: 192948

End: 193949

Strand: Reverse

Name: eutB

Synonym: RHE_PF00182

Alternate gene names: 86360913

Gene position: 193949-192948 (Counterclockwise)

Preceding gene: 86360914

Following gene: 86360912

Centisome position: 30.19

GC content: 66.37

Gene sequence:

>1002_bases
ATGGTGAGCAGCTTGCCGGTTTCGCTGGAGGATATTCGCGCAGCGGCGCGGCGGATCGCCGGCTGGGTCGTCGAAACACC
GATGGTGCTGTCGGCATCGCTTGCCGAGATTTCCGGCGTTCCGGTGTGGCTGAAGCTCGAACATCACCAGACGACTGGCA
GCTTCAAACTGCGCGGGGCGACCAATGCGGTGCTGTCATTGTCACCGGTAGAACGCGCGCGCGGTGTCGTCGCCGCCTCG
ACCGGAAATCACGGCCGGGCGCTTGCTCATGCCGCGAAGGCGCAAGGCGCGGTTGCGACGATCTGCATGTCGCGGCTGGT
GCCAGAGAACAAGGTTGCGGAAATCCGCCGTCTCGGCGCCGATGTGCGCATCGTCGGGCGATCGCAGGACGAGGCGCAGC
AGGAAGTCGACCGGCTGGTGCGAGAGGAGGGGCTGGTGATGATCCCACCTTTTGACCATCCCGACGTCGTCGCCGGGCAG
GGGACGCTCGGGCTCGATATCGTCGACGCCTTGCCTGAGGTGGCAACAGTGCTGGTGCCGCTTTCAGGCGGCGGCCTTGC
GGCGGGCGTCGCCGCCGCGATCAAGGGTGTCAATCCCAAGATGAAGGTGATCGGCCTGACGATGGAACGGGGCGCGGCGA
TGAAGGCGAGCCTCGATGCCGGACGGCCGGTGCAGGTCGAGGAGGTGAGGAGCCTTGCCGACTCTCTCGGCGGCGGCATC
GGCCTCGACAATCGCGTGACTTTCACTATGTGCCGGGCGCTTCTTGACGACGTCGTCCTGCTGACCGAGGCGGAGATCGC
CGCAGGCATGCGTCATGCCTATGCCTGCGAGCGCGAGATCACCGAGGGCGCGGGAGCAGTCGGCATCGCAGCGCTGCTGG
CGGGCAAGATCAGCCCCGGCGGCCCGATCGTTGCGATCCTTTCCGGGCGGAATGTCGACATGGAACAGCACCGCCGGGTG
ATCAACGGCGAGGGTGCGGCATTCACGGAGGATGGCCCATGA

Upstream 100 bases:

>100_bases
CTCGCAACCGCCTGGGCCTGCCTAAGGCTTTGCGGCGATGATCGGGCGCGGCCCGAGCTCGGTCAGCTGATGACGATGCC
CTATGGGGAAGGCTGAGATC

Downstream 100 bases:

>100_bases
ACCGCATGATCATTCTGACGGAAGCGGAATTGCGAGTGATTGTCGGGCTTGATCCCGACGCGGTCGCTTGCGTCGAGCAG
GCCTTCGCCGCGCTTGCAAC

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MVSSLPVSLEDIRAAARRIAGWVVETPMVLSASLAEISGVPVWLKLEHHQTTGSFKLRGATNAVLSLSPVERARGVVAAS
TGNHGRALAHAAKAQGAVATICMSRLVPENKVAEIRRLGADVRIVGRSQDEAQQEVDRLVREEGLVMIPPFDHPDVVAGQ
GTLGLDIVDALPEVATVLVPLSGGGLAAGVAAAIKGVNPKMKVIGLTMERGAAMKASLDAGRPVQVEEVRSLADSLGGGI
GLDNRVTFTMCRALLDDVVLLTEAEIAAGMRHAYACEREITEGAGAVGIAALLAGKISPGGPIVAILSGRNVDMEQHRRV
INGEGAAFTEDGP

Sequences:

>Translated_333_residues
MVSSLPVSLEDIRAAARRIAGWVVETPMVLSASLAEISGVPVWLKLEHHQTTGSFKLRGATNAVLSLSPVERARGVVAAS
TGNHGRALAHAAKAQGAVATICMSRLVPENKVAEIRRLGADVRIVGRSQDEAQQEVDRLVREEGLVMIPPFDHPDVVAGQ
GTLGLDIVDALPEVATVLVPLSGGGLAAGVAAAIKGVNPKMKVIGLTMERGAAMKASLDAGRPVQVEEVRSLADSLGGGI
GLDNRVTFTMCRALLDDVVLLTEAEIAAGMRHAYACEREITEGAGAVGIAALLAGKISPGGPIVAILSGRNVDMEQHRRV
INGEGAAFTEDGP
>Mature_333_residues
MVSSLPVSLEDIRAAARRIAGWVVETPMVLSASLAEISGVPVWLKLEHHQTTGSFKLRGATNAVLSLSPVERARGVVAAS
TGNHGRALAHAAKAQGAVATICMSRLVPENKVAEIRRLGADVRIVGRSQDEAQQEVDRLVREEGLVMIPPFDHPDVVAGQ
GTLGLDIVDALPEVATVLVPLSGGGLAAGVAAAIKGVNPKMKVIGLTMERGAAMKASLDAGRPVQVEEVRSLADSLGGGI
GLDNRVTFTMCRALLDDVVLLTEAEIAAGMRHAYACEREITEGAGAVGIAALLAGKISPGGPIVAILSGRNVDMEQHRRV
INGEGAAFTEDGP

Specific function: Acts On Both Serine And Threonine, And Properly Considered As A Hydroxy Amino Acid Deaminase. [C]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=323, Percent_Identity=33.7461300309598, Blast_Score=164, Evalue=8e-41,
Organism=Homo sapiens, GI19923959, Length=274, Percent_Identity=30.2919708029197, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1789505, Length=319, Percent_Identity=38.2445141065831, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1790207, Length=298, Percent_Identity=35.9060402684564, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71991565, Length=313, Percent_Identity=36.741214057508, Blast_Score=164, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17537387, Length=308, Percent_Identity=35.7142857142857, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17508781, Length=317, Percent_Identity=27.1293375394322, Blast_Score=110, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6322631, Length=324, Percent_Identity=34.8765432098765, Blast_Score=166, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6320930, Length=316, Percent_Identity=36.0759493670886, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319788, Length=269, Percent_Identity=26.7657992565056, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355833, Length=310, Percent_Identity=36.4516129032258, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24645328, Length=214, Percent_Identity=35.5140186915888, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014333
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 34533; Mature: 34533

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSLPVSLEDIRAAARRIAGWVVETPMVLSASLAEISGVPVWLKLEHHQTTGSFKLRGA
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEECCC
TNAVLSLSPVERARGVVAASTGNHGRALAHAAKAQGAVATICMSRLVPENKVAEIRRLGA
CCEEEEECHHHHHCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCC
DVRIVGRSQDEAQQEVDRLVREEGLVMIPPFDHPDVVAGQGTLGLDIVDALPEVATVLVP
CEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCCCCEECCCCCCHHHHHHHHHHEEEEEE
LSGGGLAAGVAAAIKGVNPKMKVIGLTMERGAAMKASLDAGRPVQVEEVRSLADSLGGGI
ECCCCHHHHHHHHHHCCCCCEEEEEEEHHCCCCEEECCCCCCCCCHHHHHHHHHHHCCCC
GLDNRVTFTMCRALLDDVVLLTEAEIAAGMRHAYACEREITEGAGAVGIAALLAGKISPG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
GPIVAILSGRNVDMEQHRRVINGEGAAFTEDGP
CCEEEEEECCCCCHHHHHHHHCCCCCEECCCCC
>Mature Secondary Structure
MVSSLPVSLEDIRAAARRIAGWVVETPMVLSASLAEISGVPVWLKLEHHQTTGSFKLRGA
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEECCC
TNAVLSLSPVERARGVVAASTGNHGRALAHAAKAQGAVATICMSRLVPENKVAEIRRLGA
CCEEEEECHHHHHCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCC
DVRIVGRSQDEAQQEVDRLVREEGLVMIPPFDHPDVVAGQGTLGLDIVDALPEVATVLVP
CEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCCCCEECCCCCCHHHHHHHHHHEEEEEE
LSGGGLAAGVAAAIKGVNPKMKVIGLTMERGAAMKASLDAGRPVQVEEVRSLADSLGGGI
ECCCCHHHHHHHHHHCCCCCEEEEEEEHHCCCCEEECCCCCCCCCHHHHHHHHHHHCCCC
GLDNRVTFTMCRALLDDVVLLTEAEIAAGMRHAYACEREITEGAGAVGIAALLAGKISPG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
GPIVAILSGRNVDMEQHRRVINGEGAAFTEDGP
CCEEEEEECCCCCHHHHHHHHCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]