Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 85859304

GI number: 85859304

Start: 1492827

End: 1494839

Strand: Direct

Name: recD [H]

Synonym: SYN_02551

Alternate gene names: 85859304

Gene position: 1492827-1494839 (Clockwise)

Preceding gene: 85859303

Following gene: 85859305

Centisome position: 46.95

GC content: 54.3

Gene sequence:

>2013_bases
ATGACGGACTTATTGAAAAGAATCCTGCGGAAAGGAGAAATGCCGATGTTGCCTGATGAGGCCCTCCTTTTTTACTTCTC
CGACCTGGATCGTCATTTCGGACGACTGATGGAAAAGATTTCCGGGGGGGACAACCAGGATGTCTTTCTGGCTGCCGCAC
TGACCAGCCGAAGCAACCGGGGTGGGCATGTCTGCCTCGATCTTGCCGAATATGCAGGCAGGCCACTCATGGCGGATATC
CGGGAGGAACCGGAAGACGAGATACTCGAGGAGATGCCCGAAAGCATCCTGCTGTCCTGTCCACCCCTTTCCATCTGGAG
GGAAACCCTGCTGGCATGCTCCGTTGTCGGAACGCCAGGTGAATACAAGCCCCTGATCCTGGATGATAAGTCGCGGCTTT
ATCTTTACCGTTACTGGTCTTATGAAGACACTCTGGTCCGTTTTATCAAATCATGCGGAAATCCAGCTGAATCGGAGGAT
TTCCGGAAAATATCAAATGTATCTCTCGATCTTTCCGGTCTTGGACATAACTTGCAGACTTTTTTCCCGGAGGATGCAGG
GCAGTTCAGGTTTGAGGATGACAAGTCGAAAATTTTTCCGGACTGGCAGAAGATCGCCGCTCTCGCCGTCCTGCGAAACC
GTCTGGTCGTCATTTCTGGAAGCCCTGGAACGGGAAAGACAACGACGGCGGCACGGGCTCTTGCTCTGCTGCAGATATTG
AGCCGCGGGCCGAAGCTGCGTATTGCCCTGGCCGCACCTACCGGAAAGGCGGCTGTCCGCCTGGACGAAGCCATGAATTC
GGCTTATGCCCGAGTCGGACTCAATGATCAACAGGGTAAGGCGATGACGGTGCACCGGTTGCTGGGGACTGTAGCCGGCT
CTCCCTATTTTCGTCACGGGCCGGGAAATCCTCTGCCATACGATGTGATTGTCGTGGATGAGGCCTCCATGGTCGATCTC
CCCCTGATGGCCAAACTGGTTCAGGCTCTCTCCCCGGCTTCCCGGCTGATACTACTGGGGGATCGGGATCAATTGGCCTC
TGTTGAGGCTGGCGCCGTGCTCGGTGATCTCTGCGGCCCCGACGATGCAGGAAATTTCTTTTCACAGGCATTTCGGCAGG
AAATCAGAAGGATGACCGGCGAGTCGTGTTTGCCGCCGGTTCCTTTCCGGCATTTGCCGCCGGTTCCTTTCCGGCATTTG
CCGCCCGTCAGTGACAGTATGGTTCAGTTGCAGAAAAACTATCGTTTCGACGAAAACAGCGGCATCGGTCAGCTCAGCAG
GGCGGTCAACCGGGGGGATAAAGACCGAGTCTTCAGCATTTTGAATTCGTCACGCTGTTCCGACATAGCCTGGGAGAATC
TGCCCGACCCGCTGGGACTGCCCCGGTTAATCGAGGAAAACTTAATTCATTACTTCAGGAAATACATGCAAATGGTTATA
AATAATGACAATCCTGAAGTTATATTTGATTATTTTGAGCGATTCAGGATTCTCTGCGCCCTTCGTCGAGGACCATTCGG
CGTGGTGTACGTCAATGCCCTGCTGGAAAGTATGCTGCGGTCGGAGCGCCTGATCGCCGGGAGCGGAAGGTGGTATCCGG
GACGGCCCATAATGATTAACCGCAACGACTATTCTCTGGGGCTCTTCAATGGGGACGTGGGCTTGACCCTTCCTGAACAC
GGCGGCAGCGGACTTTCCGTTTTCTTCAGAGACTCCGAAGGGAATTTCCGCCGTTTCGCTCCATTTCGGCTTCCGGAACA
TGAAACCGTATACGCCATGACCGTGCACAAGAGTCAGGGATCAGAGTTTGACGAGGTTCTGATGATTCTGTCCGATCGGG
ATTCGCCGTTGTTGACTCGGGAACTGATTTACACAGGCGTATCGCGGGCGAAGAAAGGTCTTCTTCTGTGGGGAAGAGAA
GATATCATACGCCAGGCCATTTCGCGCCGCATTAAACGGACATCCGGACTTCGTGACGCGTTGTGGGAAAGCGCGGATGT
CTCAGACTCCTGA

Upstream 100 bases:

>100_bases
GGGATTTATTATCTATTTCTTCGGGGCATCGATCCAAGCCGGGGAGAAAAAACGGGCGTTTATTTCGATCGGCCGTCAGA
GGCGCGGCTGACTGCGCTGT

Downstream 100 bases:

>100_bases
AGGGTGAAAAAGCGTGGTGAGGCAGACAGTGCCGAAGCGTCCATATTGACACCATAAAAAGGCTCTGATATTTCAGTTCA
GGATGGGTTCAGGATCATGC

Product: exodeoxyribonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 670; Mature: 669

Protein sequence:

>670_residues
MTDLLKRILRKGEMPMLPDEALLFYFSDLDRHFGRLMEKISGGDNQDVFLAAALTSRSNRGGHVCLDLAEYAGRPLMADI
REEPEDEILEEMPESILLSCPPLSIWRETLLACSVVGTPGEYKPLILDDKSRLYLYRYWSYEDTLVRFIKSCGNPAESED
FRKISNVSLDLSGLGHNLQTFFPEDAGQFRFEDDKSKIFPDWQKIAALAVLRNRLVVISGSPGTGKTTTAARALALLQIL
SRGPKLRIALAAPTGKAAVRLDEAMNSAYARVGLNDQQGKAMTVHRLLGTVAGSPYFRHGPGNPLPYDVIVVDEASMVDL
PLMAKLVQALSPASRLILLGDRDQLASVEAGAVLGDLCGPDDAGNFFSQAFRQEIRRMTGESCLPPVPFRHLPPVPFRHL
PPVSDSMVQLQKNYRFDENSGIGQLSRAVNRGDKDRVFSILNSSRCSDIAWENLPDPLGLPRLIEENLIHYFRKYMQMVI
NNDNPEVIFDYFERFRILCALRRGPFGVVYVNALLESMLRSERLIAGSGRWYPGRPIMINRNDYSLGLFNGDVGLTLPEH
GGSGLSVFFRDSEGNFRRFAPFRLPEHETVYAMTVHKSQGSEFDEVLMILSDRDSPLLTRELIYTGVSRAKKGLLLWGRE
DIIRQAISRRIKRTSGLRDALWESADVSDS

Sequences:

>Translated_670_residues
MTDLLKRILRKGEMPMLPDEALLFYFSDLDRHFGRLMEKISGGDNQDVFLAAALTSRSNRGGHVCLDLAEYAGRPLMADI
REEPEDEILEEMPESILLSCPPLSIWRETLLACSVVGTPGEYKPLILDDKSRLYLYRYWSYEDTLVRFIKSCGNPAESED
FRKISNVSLDLSGLGHNLQTFFPEDAGQFRFEDDKSKIFPDWQKIAALAVLRNRLVVISGSPGTGKTTTAARALALLQIL
SRGPKLRIALAAPTGKAAVRLDEAMNSAYARVGLNDQQGKAMTVHRLLGTVAGSPYFRHGPGNPLPYDVIVVDEASMVDL
PLMAKLVQALSPASRLILLGDRDQLASVEAGAVLGDLCGPDDAGNFFSQAFRQEIRRMTGESCLPPVPFRHLPPVPFRHL
PPVSDSMVQLQKNYRFDENSGIGQLSRAVNRGDKDRVFSILNSSRCSDIAWENLPDPLGLPRLIEENLIHYFRKYMQMVI
NNDNPEVIFDYFERFRILCALRRGPFGVVYVNALLESMLRSERLIAGSGRWYPGRPIMINRNDYSLGLFNGDVGLTLPEH
GGSGLSVFFRDSEGNFRRFAPFRLPEHETVYAMTVHKSQGSEFDEVLMILSDRDSPLLTRELIYTGVSRAKKGLLLWGRE
DIIRQAISRRIKRTSGLRDALWESADVSDS
>Mature_669_residues
TDLLKRILRKGEMPMLPDEALLFYFSDLDRHFGRLMEKISGGDNQDVFLAAALTSRSNRGGHVCLDLAEYAGRPLMADIR
EEPEDEILEEMPESILLSCPPLSIWRETLLACSVVGTPGEYKPLILDDKSRLYLYRYWSYEDTLVRFIKSCGNPAESEDF
RKISNVSLDLSGLGHNLQTFFPEDAGQFRFEDDKSKIFPDWQKIAALAVLRNRLVVISGSPGTGKTTTAARALALLQILS
RGPKLRIALAAPTGKAAVRLDEAMNSAYARVGLNDQQGKAMTVHRLLGTVAGSPYFRHGPGNPLPYDVIVVDEASMVDLP
LMAKLVQALSPASRLILLGDRDQLASVEAGAVLGDLCGPDDAGNFFSQAFRQEIRRMTGESCLPPVPFRHLPPVPFRHLP
PVSDSMVQLQKNYRFDENSGIGQLSRAVNRGDKDRVFSILNSSRCSDIAWENLPDPLGLPRLIEENLIHYFRKYMQMVIN
NDNPEVIFDYFERFRILCALRRGPFGVVYVNALLESMLRSERLIAGSGRWYPGRPIMINRNDYSLGLFNGDVGLTLPEHG
GSGLSVFFRDSEGNFRRFAPFRLPEHETVYAMTVHKSQGSEFDEVLMILSDRDSPLLTRELIYTGVSRAKKGLLLWGRED
IIRQAISRRIKRTSGLRDALWESADVSDS

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=629, Percent_Identity=42.9252782193959, Blast_Score=415, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 75106; Mature: 74975

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLLKRILRKGEMPMLPDEALLFYFSDLDRHFGRLMEKISGGDNQDVFLAAALTSRSNR
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCC
GGHVCLDLAEYAGRPLMADIREEPEDEILEEMPESILLSCPPLSIWRETLLACSVVGTPG
CCEEEEEHHHHCCCCEEHHHHCCCHHHHHHHCCHHHEECCCCHHHHHHHHHHHHEECCCC
EYKPLILDDKSRLYLYRYWSYEDTLVRFIKSCGNPAESEDFRKISNVSLDLSGLGHNLQT
CCCCEEECCCCCEEEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHCCEEEECCCCCCHHH
FFPEDAGQFRFEDDKSKIFPDWQKIAALAVLRNRLVVISGSPGTGKTTTAARALALLQIL
CCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHH
SRGPKLRIALAAPTGKAAVRLDEAMNSAYARVGLNDQQGKAMTVHRLLGTVAGSPYFRHG
HCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEECC
PGNPLPYDVIVVDEASMVDLPLMAKLVQALSPASRLILLGDRDQLASVEAGAVLGDLCGP
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCC
DDAGNFFSQAFRQEIRRMTGESCLPPVPFRHLPPVPFRHLPPVSDSMVQLQKNYRFDENS
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
GIGQLSRAVNRGDKDRVFSILNSSRCSDIAWENLPDPLGLPRLIEENLIHYFRKYMQMVI
CHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NNDNPEVIFDYFERFRILCALRRGPFGVVYVNALLESMLRSERLIAGSGRWYPGRPIMIN
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCEEECCCCCCCCCCEEEE
RNDYSLGLFNGDVGLTLPEHGGSGLSVFFRDSEGNFRRFAPFRLPEHETVYAMTVHKSQG
CCCCEEEEEECCEEEEECCCCCCCEEEEEECCCCCEEEECCCCCCCCCEEEEEEEECCCC
SEFDEVLMILSDRDSPLLTRELIYTGVSRAKKGLLLWGREDIIRQAISRRIKRTSGLRDA
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHCCHHHH
LWESADVSDS
HHCCCCCCCC
>Mature Secondary Structure 
TDLLKRILRKGEMPMLPDEALLFYFSDLDRHFGRLMEKISGGDNQDVFLAAALTSRSNR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCC
GGHVCLDLAEYAGRPLMADIREEPEDEILEEMPESILLSCPPLSIWRETLLACSVVGTPG
CCEEEEEHHHHCCCCEEHHHHCCCHHHHHHHCCHHHEECCCCHHHHHHHHHHHHEECCCC
EYKPLILDDKSRLYLYRYWSYEDTLVRFIKSCGNPAESEDFRKISNVSLDLSGLGHNLQT
CCCCEEECCCCCEEEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHCCEEEECCCCCCHHH
FFPEDAGQFRFEDDKSKIFPDWQKIAALAVLRNRLVVISGSPGTGKTTTAARALALLQIL
CCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHH
SRGPKLRIALAAPTGKAAVRLDEAMNSAYARVGLNDQQGKAMTVHRLLGTVAGSPYFRHG
HCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEECC
PGNPLPYDVIVVDEASMVDLPLMAKLVQALSPASRLILLGDRDQLASVEAGAVLGDLCGP
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCC
DDAGNFFSQAFRQEIRRMTGESCLPPVPFRHLPPVPFRHLPPVSDSMVQLQKNYRFDENS
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
GIGQLSRAVNRGDKDRVFSILNSSRCSDIAWENLPDPLGLPRLIEENLIHYFRKYMQMVI
CHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NNDNPEVIFDYFERFRILCALRRGPFGVVYVNALLESMLRSERLIAGSGRWYPGRPIMIN
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCEEECCCCCCCCCCEEEE
RNDYSLGLFNGDVGLTLPEHGGSGLSVFFRDSEGNFRRFAPFRLPEHETVYAMTVHKSQG
CCCCEEEEEECCEEEEECCCCCCCEEEEEECCCCCEEEECCCCCCCCCEEEEEEEECCCC
SEFDEVLMILSDRDSPLLTRELIYTGVSRAKKGLLLWGREDIIRQAISRRIKRTSGLRDA
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHCCHHHH
LWESADVSDS
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]