Click here to switch to the map view.

The map label for this gene is atoC [C]

Identifier: 85859214

GI number: 85859214

Start: 1392497

End: 1393981

Strand: Direct

Name: atoC [C]

Synonym: SYN_02801

Alternate gene names: 85859214

Gene position: 1392497-1393981 (Clockwise)

Preceding gene: 85859206

Following gene: 85859215

Centisome position: 43.8

GC content: 40.54

Gene sequence:

>1485_bases
ATGATGGAGCGTGCACTGAAAATCGAGAATTATTCGACCGATCAAAAAAGGATCCTGATTGTTGATGATTATCCACAACT
GCGGACAGTCGTCAAAGAGGCATTGGAACGAGAAGGAAATTATGAAGTCAATGAAGCTGAAAATGGTTTAGAAGCCTTGA
AACTTCTCCAGAACGCTGACTATGACATGATCATCAGTGATGTGATGATGCCGGGGATGGGTGGAATTGATTTGTTGAAA
AGTATTAAGGAGGTCCGGTCTAATGCGGTGACGATCATGATTACGGCGTATCCGGCAGTTGAAACGACCGTTTCGGCCAT
TAAAAAAGGCGCCATAGACTTTATAAAAAAACCTTTCGATATCGATGAGCTGTTGTTTAAAGTGAATTTATATTTGCGTA
AAAAGCAGACTGTATCCAATCGGGAATCAGAAAAGGATATAAAACACTTTTTCTTGGGAGATGAGCCTGATGAATTATTG
CTTTATAATTACATTTATGACGCCATAGAAAATTCCTTTGGTGATAATAATTTCATTTTTGAGAATGTTGTCGAGTTGGC
AATGCAGATTGTCGGAGGAAAAGATTGTGCGCTTCTCCTTTATGAAGAGGATGAGCAACAGTTTCATCCCCAAATCATTT
CCGGAATTGATCCTGAAACTTACAATTTAAAGATCTTGCCCCATATTTCAGATATATTTAAAGAGGTAGCGGATGCCAAG
GGGGCGGTTGTTGTCCACTCCGATGAAAATCCCGGAGTATCGCCTTCTTTGATCTGTGCCCCATTAATGATCAGGAATAA
GGTATTCGGTATTTTAAGTATAAGGAAAAAAGGGCGGGGAGAGCGGTTCTCTAAGAAGGAACTGAATTATATATTAATTT
TGACCAAGCGTTCTTCACTCAATGTCGAAAATAAGATCCTGTATGAAAGTCTTTACCGGAGTCTTTTGGATACGTTTAAA
TCATTGGTTGCGTCCATACAGGTTCGTGATTCTTATACTGAGGAACATTCCTGTCGGGTTACGGAGTTGGCGGTGAATGT
GGCAAGAAGCATGGGCTGCACATCAGAGGATATCGAGAGCATACGAATTGCAGGAATGCTGCATGATATCGGCAAGATTG
CCATTCCCGACAGGATTTTGCTCAAGCCTGATAAACTCATGGATTATGAATATCAGGTCATCAAAAGTCATCCCGGCATA
GGGGAACGGATATTAAAGCCAGTCATGCTTCTGGAAAAAGAAAGAAAAATTATCCTGCACCATCATGAACGTTACGATGG
GAAAGGATATCCCAATGGACTTTCGGGTGAAAATATCCCTTTTTTATCCAGGTTGCTGGCCATTGCGGATTCTTATGACG
CAATGACAAACAATCGCCCATATCGATATGCCATGCCAATCGATGATGCTATTGGTGAACTTAGGAAAAACAGCAATCAG
CAATTTGACGGACATATTGTCGAATGTTTTTTACAAAACATATAA

Upstream 100 bases:

>100_bases
TGAAAAAATATCATATAATATTTGCGATCTTATTTTGAAAAGTGTGGGGTGTTGATCCAGGAATTTAACATGATGGGAAT
TATCCTGTAAGGGAAAACCA

Downstream 100 bases:

>100_bases
TCAACTGAACCAGTTTATGCATATTGTTTAGGTGATGCTCATTAATGGCCTCATGAAAAATTCTCGTGTGGTGACTCCAG
TTGTTTTTACTCAAGTTGAA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MMERALKIENYSTDQKRILIVDDYPQLRTVVKEALEREGNYEVNEAENGLEALKLLQNADYDMIISDVMMPGMGGIDLLK
SIKEVRSNAVTIMITAYPAVETTVSAIKKGAIDFIKKPFDIDELLFKVNLYLRKKQTVSNRESEKDIKHFFLGDEPDELL
LYNYIYDAIENSFGDNNFIFENVVELAMQIVGGKDCALLLYEEDEQQFHPQIISGIDPETYNLKILPHISDIFKEVADAK
GAVVVHSDENPGVSPSLICAPLMIRNKVFGILSIRKKGRGERFSKKELNYILILTKRSSLNVENKILYESLYRSLLDTFK
SLVASIQVRDSYTEEHSCRVTELAVNVARSMGCTSEDIESIRIAGMLHDIGKIAIPDRILLKPDKLMDYEYQVIKSHPGI
GERILKPVMLLEKERKIILHHHERYDGKGYPNGLSGENIPFLSRLLAIADSYDAMTNNRPYRYAMPIDDAIGELRKNSNQ
QFDGHIVECFLQNI

Sequences:

>Translated_494_residues
MMERALKIENYSTDQKRILIVDDYPQLRTVVKEALEREGNYEVNEAENGLEALKLLQNADYDMIISDVMMPGMGGIDLLK
SIKEVRSNAVTIMITAYPAVETTVSAIKKGAIDFIKKPFDIDELLFKVNLYLRKKQTVSNRESEKDIKHFFLGDEPDELL
LYNYIYDAIENSFGDNNFIFENVVELAMQIVGGKDCALLLYEEDEQQFHPQIISGIDPETYNLKILPHISDIFKEVADAK
GAVVVHSDENPGVSPSLICAPLMIRNKVFGILSIRKKGRGERFSKKELNYILILTKRSSLNVENKILYESLYRSLLDTFK
SLVASIQVRDSYTEEHSCRVTELAVNVARSMGCTSEDIESIRIAGMLHDIGKIAIPDRILLKPDKLMDYEYQVIKSHPGI
GERILKPVMLLEKERKIILHHHERYDGKGYPNGLSGENIPFLSRLLAIADSYDAMTNNRPYRYAMPIDDAIGELRKNSNQ
QFDGHIVECFLQNI
>Mature_494_residues
MMERALKIENYSTDQKRILIVDDYPQLRTVVKEALEREGNYEVNEAENGLEALKLLQNADYDMIISDVMMPGMGGIDLLK
SIKEVRSNAVTIMITAYPAVETTVSAIKKGAIDFIKKPFDIDELLFKVNLYLRKKQTVSNRESEKDIKHFFLGDEPDELL
LYNYIYDAIENSFGDNNFIFENVVELAMQIVGGKDCALLLYEEDEQQFHPQIISGIDPETYNLKILPHISDIFKEVADAK
GAVVVHSDENPGVSPSLICAPLMIRNKVFGILSIRKKGRGERFSKKELNYILILTKRSSLNVENKILYESLYRSLLDTFK
SLVASIQVRDSYTEEHSCRVTELAVNVARSMGCTSEDIESIRIAGMLHDIGKIAIPDRILLKPDKLMDYEYQVIKSHPGI
GERILKPVMLLEKERKIILHHHERYDGKGYPNGLSGENIPFLSRLLAIADSYDAMTNNRPYRYAMPIDDAIGELRKNSNQ
QFDGHIVECFLQNI

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=134, Percent_Identity=37.3134328358209, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790299, Length=106, Percent_Identity=40.5660377358491, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=36.6666666666667, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790437, Length=107, Percent_Identity=40.1869158878505, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786784, Length=122, Percent_Identity=31.9672131147541, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082012, Length=124, Percent_Identity=31.4516129032258, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788905, Length=107, Percent_Identity=36.4485981308411, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786599, Length=121, Percent_Identity=33.0578512396694, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789809, Length=127, Percent_Identity=29.1338582677165, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789402, Length=133, Percent_Identity=27.0676691729323, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR003607 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 56281; Mature: 56281

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMERALKIENYSTDQKRILIVDDYPQLRTVVKEALEREGNYEVNEAENGLEALKLLQNAD
CCCCCEECCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC
YDMIISDVMMPGMGGIDLLKSIKEVRSNAVTIMITAYPAVETTVSAIKKGAIDFIKKPFD
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCC
IDELLFKVNLYLRKKQTVSNRESEKDIKHFFLGDEPDELLLYNYIYDAIENSFGDNNFIF
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHH
ENVVELAMQIVGGKDCALLLYEEDEQQFHPQIISGIDPETYNLKILPHISDIFKEVADAK
HHHHHHHHHHHCCCCEEEEEEECCCHHHCHHHHCCCCCCCEEEEECCCHHHHHHHHHCCC
GAVVVHSDENPGVSPSLICAPLMIRNKVFGILSIRKKGRGERFSKKELNYILILTKRSSL
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCC
NVENKILYESLYRSLLDTFKSLVASIQVRDSYTEEHSCRVTELAVNVARSMGCTSEDIES
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
IRIAGMLHDIGKIAIPDRILLKPDKLMDYEYQVIKSHPGIGERILKPVMLLEKERKIILH
HHHHHHHHHHCCCCCCCCEEECCHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEE
HHERYDGKGYPNGLSGENIPFLSRLLAIADSYDAMTNNRPYRYAMPIDDAIGELRKNSNQ
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCC
QFDGHIVECFLQNI
CCCHHHHHHHHHCC
>Mature Secondary Structure
MMERALKIENYSTDQKRILIVDDYPQLRTVVKEALEREGNYEVNEAENGLEALKLLQNAD
CCCCCEECCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC
YDMIISDVMMPGMGGIDLLKSIKEVRSNAVTIMITAYPAVETTVSAIKKGAIDFIKKPFD
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCC
IDELLFKVNLYLRKKQTVSNRESEKDIKHFFLGDEPDELLLYNYIYDAIENSFGDNNFIF
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHH
ENVVELAMQIVGGKDCALLLYEEDEQQFHPQIISGIDPETYNLKILPHISDIFKEVADAK
HHHHHHHHHHHCCCCEEEEEEECCCHHHCHHHHCCCCCCCEEEEECCCHHHHHHHHHCCC
GAVVVHSDENPGVSPSLICAPLMIRNKVFGILSIRKKGRGERFSKKELNYILILTKRSSL
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCC
NVENKILYESLYRSLLDTFKSLVASIQVRDSYTEEHSCRVTELAVNVARSMGCTSEDIES
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
IRIAGMLHDIGKIAIPDRILLKPDKLMDYEYQVIKSHPGIGERILKPVMLLEKERKIILH
HHHHHHHHHHCCCCCCCCEEECCHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEE
HHERYDGKGYPNGLSGENIPFLSRLLAIADSYDAMTNNRPYRYAMPIDDAIGELRKNSNQ
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCC
QFDGHIVECFLQNI
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]