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The map label for this gene is mshA [H]

Identifier: 85858267

GI number: 85858267

Start: 426201

End: 427355

Strand: Direct

Name: mshA [H]

Synonym: SYN_01106

Alternate gene names: 85858267

Gene position: 426201-427355 (Clockwise)

Preceding gene: 85858266

Following gene: 85858268

Centisome position: 13.41

GC content: 33.33

Gene sequence:

>1155_bases
ATGAAAGTGTTGGTTGTTGATAATAGCAGATGGTGGGGTGGGGCAGAAAAAAATCTTCAAACTCTTGTTGATAACAGAAG
TAATGCCATTGAATTTAATGTACTGTCTGATTATCCAATGAGTCATAATATTACTTATAGAGATTTTTGTGGTGTCCGAT
ACCGATTTGACAACTCATATTTTATTAGGTATCTGGATAACAAATATCAAATCAAAGGAATGAGAATATTTCGATTGATT
TATAAGTCTTTATATTTAATTCCATCTCTTGTAAGGTATAATCCGGATATAGTCCATTTTAATTTATATAGAAGTTCTGA
TATATTAGATATCATTGTCTGTAAAATCTTAAGAAAGAAAGTGGTATTACATATTCGCTCATTGGCAAATCGAATAAAAA
TAGCCCCCTTGACAATCAAATTGGCAGACGCAGTGATATGTGTTTCTAAATCAGTCAAACAAGGATTTTCTTTTACTGGC
AATAAATATCATGTCATTTATAATGGTATTGACTCAAAGTATTATCATCTTGTTCCCCAAGATCAAGCAAGAGAAAAACT
TGGAATCAACTTAACAAGCTTTGTCATCGGGTCGATTGGCAATCTTGAACGTGAGAAAGGTCACGATGTTGCTGTGAAAG
CACTGAAAAAAATTATTGATGATGGAAATGTTGTAGTAGCACTAATTATTGTAGGGAAAGATTCAACAATTAATGAGTCG
GAAACAAAAAGAATATTAACATTGAGCAAAGATTTAGGTGTTCAAGGCCATATTAAAATATTTTCAATATCTCACAAGGA
TATTCACTATGTATATAGTGCCTGTGATATTGTGTTGACACTTTGTATCGATGGGGAAGCTTTTGGTATGATTCCTTTAG
AAGCAGCAATGCACAATCGTCCCGTTATCGCTACGAATGTAGGTGCATGCAGAGAGACAATCATCCATAACCAAACAGGG
CTTTTATGTGAACCTAATTCACCAGTTGCTTTGGTTCAGGCTATTGACACTATTATGAAAGATAAAAAATATTGTGATCA
ACTTACCGAAAGCGCCAGGAATCGTGTTTTACATAAGTATTCAGCCGATGCATACCGTGATTCAGTATATAAAATTTACA
TAACGATTACGAAGGAAAATAAGAGAAAACTTTAA

Upstream 100 bases:

>100_bases
TGCAAGTATTATAAACACGTTAACGTAATTTTGGCGTTTATTTAAACCATCAAAATCAGGCTCCGTTTGCGGAGTTGTGC
AAAGGTTTTAGAAGATTTCA

Downstream 100 bases:

>100_bases
CTATGGTAAATCATGGGTTAACAATGTATAAGTTGTGCTTTAGATTATTCTCGCATACTATTGACATAAATTTGCCTTTG
TTTTTTTCTGTTTTTCTAAT

Product: glycosyltransferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKVLVVDNSRWWGGAEKNLQTLVDNRSNAIEFNVLSDYPMSHNITYRDFCGVRYRFDNSYFIRYLDNKYQIKGMRIFRLI
YKSLYLIPSLVRYNPDIVHFNLYRSSDILDIIVCKILRKKVVLHIRSLANRIKIAPLTIKLADAVICVSKSVKQGFSFTG
NKYHVIYNGIDSKYYHLVPQDQAREKLGINLTSFVIGSIGNLEREKGHDVAVKALKKIIDDGNVVVALIIVGKDSTINES
ETKRILTLSKDLGVQGHIKIFSISHKDIHYVYSACDIVLTLCIDGEAFGMIPLEAAMHNRPVIATNVGACRETIIHNQTG
LLCEPNSPVALVQAIDTIMKDKKYCDQLTESARNRVLHKYSADAYRDSVYKIYITITKENKRKL

Sequences:

>Translated_384_residues
MKVLVVDNSRWWGGAEKNLQTLVDNRSNAIEFNVLSDYPMSHNITYRDFCGVRYRFDNSYFIRYLDNKYQIKGMRIFRLI
YKSLYLIPSLVRYNPDIVHFNLYRSSDILDIIVCKILRKKVVLHIRSLANRIKIAPLTIKLADAVICVSKSVKQGFSFTG
NKYHVIYNGIDSKYYHLVPQDQAREKLGINLTSFVIGSIGNLEREKGHDVAVKALKKIIDDGNVVVALIIVGKDSTINES
ETKRILTLSKDLGVQGHIKIFSISHKDIHYVYSACDIVLTLCIDGEAFGMIPLEAAMHNRPVIATNVGACRETIIHNQTG
LLCEPNSPVALVQAIDTIMKDKKYCDQLTESARNRVLHKYSADAYRDSVYKIYITITKENKRKL
>Mature_384_residues
MKVLVVDNSRWWGGAEKNLQTLVDNRSNAIEFNVLSDYPMSHNITYRDFCGVRYRFDNSYFIRYLDNKYQIKGMRIFRLI
YKSLYLIPSLVRYNPDIVHFNLYRSSDILDIIVCKILRKKVVLHIRSLANRIKIAPLTIKLADAVICVSKSVKQGFSFTG
NKYHVIYNGIDSKYYHLVPQDQAREKLGINLTSFVIGSIGNLEREKGHDVAVKALKKIIDDGNVVVALIIVGKDSTINES
ETKRILTLSKDLGVQGHIKIFSISHKDIHYVYSACDIVLTLCIDGEAFGMIPLEAAMHNRPVIATNVGACRETIIHNQTG
LLCEPNSPVALVQAIDTIMKDKKYCDQLTESARNRVLHKYSADAYRDSVYKIYITITKENKRKL

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI14861836, Length=192, Percent_Identity=32.2916666666667, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357469, Length=278, Percent_Identity=25.1798561151079, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 43784; Mature: 43784

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVVDNSRWWGGAEKNLQTLVDNRSNAIEFNVLSDYPMSHNITYRDFCGVRYRFDNSY
CEEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHCCEEEEECCCE
FIRYLDNKYQIKGMRIFRLIYKSLYLIPSLVRYNPDIVHFNLYRSSDILDIIVCKILRKK
EEEEECCEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHH
VVLHIRSLANRIKIAPLTIKLADAVICVSKSVKQGFSFTGNKYHVIYNGIDSKYYHLVPQ
HHHHHHHHHHHEEEEEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEECCC
DQAREKLGINLTSFVIGSIGNLEREKGHDVAVKALKKIIDDGNVVVALIIVGKDSTINES
HHHHHHHCCCHHHHHHHCCCCCCHHCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCC
ETKRILTLSKDLGVQGHIKIFSISHKDIHYVYSACDIVLTLCIDGEAFGMIPLEAAMHNR
CCCEEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHEEEEEEECCCCCCEEEHHHHHCCC
PVIATNVGACRETIIHNQTGLLCEPNSPVALVQAIDTIMKDKKYCDQLTESARNRVLHKY
CEEEECCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SADAYRDSVYKIYITITKENKRKL
CCHHHCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure
MKVLVVDNSRWWGGAEKNLQTLVDNRSNAIEFNVLSDYPMSHNITYRDFCGVRYRFDNSY
CEEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHCCEEEEECCCE
FIRYLDNKYQIKGMRIFRLIYKSLYLIPSLVRYNPDIVHFNLYRSSDILDIIVCKILRKK
EEEEECCEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHH
VVLHIRSLANRIKIAPLTIKLADAVICVSKSVKQGFSFTGNKYHVIYNGIDSKYYHLVPQ
HHHHHHHHHHHEEEEEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEECCC
DQAREKLGINLTSFVIGSIGNLEREKGHDVAVKALKKIIDDGNVVVALIIVGKDSTINES
HHHHHHHCCCHHHHHHHCCCCCCHHCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCC
ETKRILTLSKDLGVQGHIKIFSISHKDIHYVYSACDIVLTLCIDGEAFGMIPLEAAMHNR
CCCEEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHEEEEEEECCCCCCEEEHHHHHCCC
PVIATNVGACRETIIHNQTGLLCEPNSPVALVQAIDTIMKDKKYCDQLTESARNRVLHKY
CEEEECCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SADAYRDSVYKIYITITKENKRKL
CCHHHCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA