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The map label for this gene is bcd [H]

Identifier: 85375823

GI number: 85375823

Start: 3020111

End: 3021202

Strand: Direct

Name: bcd [H]

Synonym: ELI_14980

Alternate gene names: 85375823

Gene position: 3020111-3021202 (Clockwise)

Preceding gene: 85375822

Following gene: 85375824

Centisome position: 98.94

GC content: 62.09

Gene sequence:

>1092_bases
ATGGATTTCGGACTTTCGCAAGACCAGGAGATGCTCTGCGACGCGATCAGCCGCACTCTTGCTGATACTTGTCCGCTCGA
TCATGTGCGCGAATGCGCGGAGGGCTCGGTTCCCTTCAGCGACAACGTGCGTTCGGCGCTGGGCGAAATCGGCATTTGGG
GAATGATGGTTCCCGAGCAACATGACGGGCTCGGGATGACAATGCTCGATGCCGCCGTTGTGGCCGAGCAGCTCGGCTAT
GCCGTCGCGCCGGTGCCCTTTATCGGTGCTCATGTTCTAGCGCCCCTTGCGCTGGCACAGGGCGGTAGCGAGGAGTTGAA
GGCGCACTGGCTGCCGAGGATAGCGAAGGGCGAAGCGCAAATCGCCGTCGCGATCGCGGAAACGGTCGAGATTCGGGACC
AGGCAGGCGTGGACTTCGACGGCATAAAGCTCGACGGAACGGCTTTGTTCGCGCTCGATTTCCTGGGAGCCGACGCGTTT
CTGGTAGCCGATACCGCCGGTCGGATGCACTTTGTACCTGGCGATGCTGCGGGTCTGGAGAAGGTTTCCCTCACGACGAT
CGACCGCACCCGGAGCGTAGGAGAATTGCGGTTTTCCGGAGTAACGGGCGAGGCTCTCGCGGACGATGGTGGGGCCACAA
GCAGGCGTCTGCGCGACGCTGGCCGGGTGCTTCTGTCGGCCGATAGTCTTGGTGCAGGCCAGGCTATGATCGAAAAAGCG
GTCGACTATGCCGGGCAGCGCGAACAGTTCGGGCGCGTGATCGGCAGCTTTCAGGCGGTCAAGCATTTGTGCGCGGAAAT
GGCTGCTCGCCACGAACCATGCCGTTCGCTGGTCTGGTATGCCGCCCATGCGTTCGATGCGACGCCCGACGAGGCTTCGC
TGGTGGCATGCCATGCCAAATCACATACGGGCGAAGTCCACCGTTTTGTCGCCCGAACCTCAACCGAGGTGCATGGGGGG
ATGGGTTTTACCGATCTCCTAGGTCTGCATTTCTGGTTCAAGCGAATCGGTTTCGACCGCCAGGTTCTGGGAGGTCCCGA
AGCGGTCCGGGCCGAAGCAGCGGCCTTGCAGGGGTGGACGCAGGTCGCATGA

Upstream 100 bases:

>100_bases
AACGCGGGCTGGAAATGCCGCGCGAACCCAAGTTCGCAACGCCTCCCGCGGCCGAACAGGCGACGGCCGTTGCAAGCGGG
CAGAATAAGGGAGCCGCCTG

Downstream 100 bases:

>100_bases
GACGATGAATTAGGCGCACGCTACCGACAAAATCGTGGCCACCAAGGAGAGAGGAATTAATACGTGATCGACTGGAACCT
TGGCGACATCCTTGATGCAA

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MDFGLSQDQEMLCDAISRTLADTCPLDHVRECAEGSVPFSDNVRSALGEIGIWGMMVPEQHDGLGMTMLDAAVVAEQLGY
AVAPVPFIGAHVLAPLALAQGGSEELKAHWLPRIAKGEAQIAVAIAETVEIRDQAGVDFDGIKLDGTALFALDFLGADAF
LVADTAGRMHFVPGDAAGLEKVSLTTIDRTRSVGELRFSGVTGEALADDGGATSRRLRDAGRVLLSADSLGAGQAMIEKA
VDYAGQREQFGRVIGSFQAVKHLCAEMAARHEPCRSLVWYAAHAFDATPDEASLVACHAKSHTGEVHRFVARTSTEVHGG
MGFTDLLGLHFWFKRIGFDRQVLGGPEAVRAEAAALQGWTQVA

Sequences:

>Translated_363_residues
MDFGLSQDQEMLCDAISRTLADTCPLDHVRECAEGSVPFSDNVRSALGEIGIWGMMVPEQHDGLGMTMLDAAVVAEQLGY
AVAPVPFIGAHVLAPLALAQGGSEELKAHWLPRIAKGEAQIAVAIAETVEIRDQAGVDFDGIKLDGTALFALDFLGADAF
LVADTAGRMHFVPGDAAGLEKVSLTTIDRTRSVGELRFSGVTGEALADDGGATSRRLRDAGRVLLSADSLGAGQAMIEKA
VDYAGQREQFGRVIGSFQAVKHLCAEMAARHEPCRSLVWYAAHAFDATPDEASLVACHAKSHTGEVHRFVARTSTEVHGG
MGFTDLLGLHFWFKRIGFDRQVLGGPEAVRAEAAALQGWTQVA
>Mature_363_residues
MDFGLSQDQEMLCDAISRTLADTCPLDHVRECAEGSVPFSDNVRSALGEIGIWGMMVPEQHDGLGMTMLDAAVVAEQLGY
AVAPVPFIGAHVLAPLALAQGGSEELKAHWLPRIAKGEAQIAVAIAETVEIRDQAGVDFDGIKLDGTALFALDFLGADAF
LVADTAGRMHFVPGDAAGLEKVSLTTIDRTRSVGELRFSGVTGEALADDGGATSRRLRDAGRVLLSADSLGAGQAMIEKA
VDYAGQREQFGRVIGSFQAVKHLCAEMAARHEPCRSLVWYAAHAFDATPDEASLVACHAKSHTGEVHRFVARTSTEVHGG
MGFTDLLGLHFWFKRIGFDRQVLGGPEAVRAEAAALQGWTQVA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=362, Percent_Identity=24.0331491712707, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508101, Length=366, Percent_Identity=25.9562841530055, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=309, Percent_Identity=26.2135922330097, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71985184, Length=373, Percent_Identity=23.5924932975871, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646207, Length=327, Percent_Identity=26.2996941896024, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356377, Length=306, Percent_Identity=26.797385620915, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 38581; Mature: 38581

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFGLSQDQEMLCDAISRTLADTCPLDHVRECAEGSVPFSDNVRSALGEIGIWGMMVPEQ
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHCCEEEEECCCC
HDGLGMTMLDAAVVAEQLGYAVAPVPFIGAHVLAPLALAQGGSEELKAHWLPRIAKGEAQ
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCE
IAVAIAETVEIRDQAGVDFDGIKLDGTALFALDFLGADAFLVADTAGRMHFVPGDAAGLE
EEEEEHHHHHHHHHCCCCCCCEEECCCEEEEEHHHCCCEEEEEECCCCEEECCCCCCCCC
KVSLTTIDRTRSVGELRFSGVTGEALADDGGATSRRLRDAGRVLLSADSLGAGQAMIEKA
EEEEEEHHHHCCCCCEEECCCCCCHHCCCCCHHHHHHHHHCCEEEECCCCCCHHHHHHHH
VDYAGQREQFGRVIGSFQAVKHLCAEMAARHEPCRSLVWYAAHAFDATPDEASLVACHAK
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEECC
SHTGEVHRFVARTSTEVHGGMGFTDLLGLHFWFKRIGFDRQVLGGPEAVRAEAAALQGWT
CCCHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCHH
QVA
HCC
>Mature Secondary Structure
MDFGLSQDQEMLCDAISRTLADTCPLDHVRECAEGSVPFSDNVRSALGEIGIWGMMVPEQ
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHCCEEEEECCCC
HDGLGMTMLDAAVVAEQLGYAVAPVPFIGAHVLAPLALAQGGSEELKAHWLPRIAKGEAQ
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCE
IAVAIAETVEIRDQAGVDFDGIKLDGTALFALDFLGADAFLVADTAGRMHFVPGDAAGLE
EEEEEHHHHHHHHHCCCCCCCEEECCCEEEEEHHHCCCEEEEEECCCCEEECCCCCCCCC
KVSLTTIDRTRSVGELRFSGVTGEALADDGGATSRRLRDAGRVLLSADSLGAGQAMIEKA
EEEEEEHHHHCCCCCEEECCCCCCHHCCCCCHHHHHHHHHCCEEEECCCCCCHHHHHHHH
VDYAGQREQFGRVIGSFQAVKHLCAEMAARHEPCRSLVWYAAHAFDATPDEASLVACHAK
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEECC
SHTGEVHRFVARTSTEVHGGMGFTDLLGLHFWFKRIGFDRQVLGGPEAVRAEAAALQGWT
CCCHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCHH
QVA
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]