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The map label for this gene is dgoR [H]

Identifier: 85375817

GI number: 85375817

Start: 3014517

End: 3015245

Strand: Direct

Name: dgoR [H]

Synonym: ELI_14950

Alternate gene names: 85375817

Gene position: 3014517-3015245 (Clockwise)

Preceding gene: 85375811

Following gene: 85375818

Centisome position: 98.76

GC content: 59.81

Gene sequence:

>729_bases
ATGCCAGCGGTGAAGAAGGCCAAGCGTGCCCTTTCTCTTGCGCAAAGCATCGTGCGGGACATCGAGGCGGGTCGCCATAA
CCCGGGTGACAGGCTTCCGCGCGAGGATGAAATGCTCGCGCGTTACGAGGTTGCGCGCGCAACTTTGCGGGAGGCTTTGC
GGTTCCTGGAATTGCAAGGGGTCATCCATCTCCAGCTCGGCCGTGGTGGAGGTCCCGTCGTAGCCCGTCCGCAGACCGGC
GATTTTGCAAGCAGTTTGTCATTGATTCTGCATTTCATGGAAGCCGATTTGCGTGGTTTGCTTGAATTGCGCGAAGCAAT
TGCTCCCGATGTCGCAGGGTATGCAGCCCAGCGTGCAACTACCGCTGATCTCAGCGCGTTGGCAGGGTGTCTGGCGGAAT
TGAGGCATCATGAAGCCTCTGATCAATTCGAGGAACTTAATCGCAGATTTCACGACTTGTTGGGTTGGGCGAGCGGCAAT
CCGCTGTTCGGTTTGCTGACCTCTGCGATGCATCTGTTGACCCGCGAGTTTTCCCATTCGCTGGGATATTCGGCACAGGA
ACGGGCGGTGCAGATGAAGTTTCTGGTGCGGGTGCTCGAGGCAGTGCGGACTGGCGACAGCGCCGCGGCCCGTCAAGCAA
TGAGCCGGTTGGTGGCCGGCTCTGCCGTCTATCTTTCGGAGCGCAGTCCCGAGCTGGTCTCGCAGCGGGTGCGGTGGGGG
CAGCTGTAG

Upstream 100 bases:

>100_bases
CAGACACCAATCCCATCGGATAGTGTGCCGATCCAGCGAAGGTTTGCTAATATCCTTATACTGTTTATTCGAGAGGTGCG
GGTGTGCTGATGAGTGGCGG

Downstream 100 bases:

>100_bases
AATTTTCAATAGTTTGAGTGTGCGTTTAGGCAAGTGGCTGGAGAGGAAGAATGGCGTTGAAGAGCCGAATATGCGAAATG
CTGGGGATCCGGTACCCGAT

Product: regulatory protein GntR, HTH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MPAVKKAKRALSLAQSIVRDIEAGRHNPGDRLPREDEMLARYEVARATLREALRFLELQGVIHLQLGRGGGPVVARPQTG
DFASSLSLILHFMEADLRGLLELREAIAPDVAGYAAQRATTADLSALAGCLAELRHHEASDQFEELNRRFHDLLGWASGN
PLFGLLTSAMHLLTREFSHSLGYSAQERAVQMKFLVRVLEAVRTGDSAAARQAMSRLVAGSAVYLSERSPELVSQRVRWG
QL

Sequences:

>Translated_242_residues
MPAVKKAKRALSLAQSIVRDIEAGRHNPGDRLPREDEMLARYEVARATLREALRFLELQGVIHLQLGRGGGPVVARPQTG
DFASSLSLILHFMEADLRGLLELREAIAPDVAGYAAQRATTADLSALAGCLAELRHHEASDQFEELNRRFHDLLGWASGN
PLFGLLTSAMHLLTREFSHSLGYSAQERAVQMKFLVRVLEAVRTGDSAAARQAMSRLVAGSAVYLSERSPELVSQRVRWG
QL
>Mature_241_residues
PAVKKAKRALSLAQSIVRDIEAGRHNPGDRLPREDEMLARYEVARATLREALRFLELQGVIHLQLGRGGGPVVARPQTGD
FASSLSLILHFMEADLRGLLELREAIAPDVAGYAAQRATTADLSALAGCLAELRHHEASDQFEELNRRFHDLLGWASGNP
LFGLLTSAMHLLTREFSHSLGYSAQERAVQMKFLVRVLEAVRTGDSAAARQAMSRLVAGSAVYLSERSPELVSQRVRWGQ
L

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=234, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26631; Mature: 26500

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAVKKAKRALSLAQSIVRDIEAGRHNPGDRLPREDEMLARYEVARATLREALRFLELQG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
VIHLQLGRGGGPVVARPQTGDFASSLSLILHFMEADLRGLLELREAIAPDVAGYAAQRAT
CEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TADLSALAGCLAELRHHEASDQFEELNRRFHDLLGWASGNPLFGLLTSAMHLLTREFSHS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LGYSAQERAVQMKFLVRVLEAVRTGDSAAARQAMSRLVAGSAVYLSERSPELVSQRVRWG
HCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHEECCCCHHHHHHHHHCC
QL
CC
>Mature Secondary Structure 
PAVKKAKRALSLAQSIVRDIEAGRHNPGDRLPREDEMLARYEVARATLREALRFLELQG
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
VIHLQLGRGGGPVVARPQTGDFASSLSLILHFMEADLRGLLELREAIAPDVAGYAAQRAT
CEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TADLSALAGCLAELRHHEASDQFEELNRRFHDLLGWASGNPLFGLLTSAMHLLTREFSHS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LGYSAQERAVQMKFLVRVLEAVRTGDSAAARQAMSRLVAGSAVYLSERSPELVSQRVRWG
HCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHEECCCCHHHHHHHHHCC
QL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]