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The map label for this gene is ltaE [H]

Identifier: 85375549

GI number: 85375549

Start: 2741350

End: 2742345

Strand: Direct

Name: ltaE [H]

Synonym: ELI_13610

Alternate gene names: 85375549

Gene position: 2741350-2742345 (Clockwise)

Preceding gene: 85375547

Following gene: 85375550

Centisome position: 89.81

GC content: 66.57

Gene sequence:

>996_bases
ATGCGTTTCCTGTCCGACAATGCCGCTACCGTCCACCCCCGCGTGTGGGAGGCGCTGCGTTTGGCAGACGGTGTCGACAC
GCCATATGACGGAGATCACTACTCGCAACGGCTCGACGAGGCTTTCGGGGAGCTGTTCGGGCGCGAGGTGGCGGTGCTGT
GGGTGGCGACCGGCACGGCGGCCAATTGTCTGGCGCTTAGCGCAATGGTGCCCCCGCATGGCGGGGTAGTGTGCCACGAA
GAGGCGCATATCGAAATGGACGAAGGCGGCGCGCCAGGATTCTACCTGCATGGCGCGAAGCTGATGCTGGCACAAGGCGA
GGGCGCGAAACTGACGCCGGACGCCATCCGCGCGGTAATCGATCCGATCCGCGACGACGTGCACCAGGTCCAGCCGCATG
CGATCTCGGTAACGCAGGCGAGCGAATATGGCCGCGCCTATCGGCCTGAAGAACTCAACGCCATCGGTGCGTTCGCGCAG
GAGCGCGGGCTGGGGCTGCATGTCGATGGTGCGCGGTTCGGCAATGCGGTGGCGTTCCTCGGCTGCTCGCCCGCCGAAGC
GGTCGGCCCGGCACAGGCCCTGAGCTTCGGTTGCGTCAAGAACGGGGCGATGAATGCAGAAGCGATCGTGTTCTTCGATC
CCGCGCTGGCCGACAGCGTGCGCTATCGTCGCAAGCGGGCGGGACACTTGCAGAGCAAGGGCCGCTTCCTCGCCGCGCAA
TTGCTGGCGATGCTGGAAGGCGATTTGTGGCTGGAGAATGCGCGCGCCGCCAATGCCGCCGCGCAGGCTATCGTCGCGGA
AGCGAGCGAGCGCCTGCTGCATCCGGTCGAGGCGAACGAGGTCTTCATGCGCCTGACCCCGCCCGAGCGCGAGGCGCTGC
GCGAGCAAGGCTATCATTTCTACGACTGGGGCGAGAATGCCGCGCGCTTGGTCGCTTCGTGGGACAGCGATCAGGAGGCC
GCGCGGGCGCTGGGCCAGGCTATCGCCAGCTTGTGA

Upstream 100 bases:

>100_bases
CTGACCCTGCACGTGGTGGGTGATCGTGACGTCCGGTTTCTCTTCGCTCATCGCAAGGCTCCTTCTTGCGCTCAACGCCT
GTATCGCTAGGGGCGTTCCG

Downstream 100 bases:

>100_bases
GCGCGACCGAAACCACCATGCTGAGCTGGCGGGTCATCCTGCCGTTCCTGCTGACCGGCACGATCTGGGGCTCGACCTGG
TTCGTGATCACGGGGCAGAT

Product: threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRFLSDNAATVHPRVWEALRLADGVDTPYDGDHYSQRLDEAFGELFGREVAVLWVATGTAANCLALSAMVPPHGGVVCHE
EAHIEMDEGGAPGFYLHGAKLMLAQGEGAKLTPDAIRAVIDPIRDDVHQVQPHAISVTQASEYGRAYRPEELNAIGAFAQ
ERGLGLHVDGARFGNAVAFLGCSPAEAVGPAQALSFGCVKNGAMNAEAIVFFDPALADSVRYRRKRAGHLQSKGRFLAAQ
LLAMLEGDLWLENARAANAAAQAIVAEASERLLHPVEANEVFMRLTPPEREALREQGYHFYDWGENAARLVASWDSDQEA
ARALGQAIASL

Sequences:

>Translated_331_residues
MRFLSDNAATVHPRVWEALRLADGVDTPYDGDHYSQRLDEAFGELFGREVAVLWVATGTAANCLALSAMVPPHGGVVCHE
EAHIEMDEGGAPGFYLHGAKLMLAQGEGAKLTPDAIRAVIDPIRDDVHQVQPHAISVTQASEYGRAYRPEELNAIGAFAQ
ERGLGLHVDGARFGNAVAFLGCSPAEAVGPAQALSFGCVKNGAMNAEAIVFFDPALADSVRYRRKRAGHLQSKGRFLAAQ
LLAMLEGDLWLENARAANAAAQAIVAEASERLLHPVEANEVFMRLTPPEREALREQGYHFYDWGENAARLVASWDSDQEA
ARALGQAIASL
>Mature_331_residues
MRFLSDNAATVHPRVWEALRLADGVDTPYDGDHYSQRLDEAFGELFGREVAVLWVATGTAANCLALSAMVPPHGGVVCHE
EAHIEMDEGGAPGFYLHGAKLMLAQGEGAKLTPDAIRAVIDPIRDDVHQVQPHAISVTQASEYGRAYRPEELNAIGAFAQ
ERGLGLHVDGARFGNAVAFLGCSPAEAVGPAQALSFGCVKNGAMNAEAIVFFDPALADSVRYRRKRAGHLQSKGRFLAAQ
LLAMLEGDLWLENARAANAAAQAIVAEASERLLHPVEANEVFMRLTPPEREALREQGYHFYDWGENAARLVASWDSDQEA
ARALGQAIASL

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=241, Percent_Identity=26.1410788381743, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320789, Length=287, Percent_Identity=25.7839721254355, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 35677; Mature: 35677

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLSDNAATVHPRVWEALRLADGVDTPYDGDHYSQRLDEAFGELFGREVAVLWVATGTA
CCEECCCCCEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCC
ANCLALSAMVPPHGGVVCHEEAHIEMDEGGAPGFYLHGAKLMLAQGEGAKLTPDAIRAVI
HHHHEEEEECCCCCCEEECCCCEEEECCCCCCCEEEECCEEEEECCCCCCCCHHHHHHHH
DPIRDDVHQVQPHAISVTQASEYGRAYRPEELNAIGAFAQERGLGLHVDGARFGNAVAFL
HHHHHHHHHCCCCEEEEEEHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEE
GCSPAEAVGPAQALSFGCVKNGAMNAEAIVFFDPALADSVRYRRKRAGHLQSKGRFLAAQ
ECCCHHHCCHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHCCHHHCCHHHHHH
LLAMLEGDLWLENARAANAAAQAIVAEASERLLHPVEANEVFMRLTPPEREALREQGYHF
HHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHCCCEE
YDWGENAARLVASWDSDQEAARALGQAIASL
EECCCCHHHEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFLSDNAATVHPRVWEALRLADGVDTPYDGDHYSQRLDEAFGELFGREVAVLWVATGTA
CCEECCCCCEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCC
ANCLALSAMVPPHGGVVCHEEAHIEMDEGGAPGFYLHGAKLMLAQGEGAKLTPDAIRAVI
HHHHEEEEECCCCCCEEECCCCEEEECCCCCCCEEEECCEEEEECCCCCCCCHHHHHHHH
DPIRDDVHQVQPHAISVTQASEYGRAYRPEELNAIGAFAQERGLGLHVDGARFGNAVAFL
HHHHHHHHHCCCCEEEEEEHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEE
GCSPAEAVGPAQALSFGCVKNGAMNAEAIVFFDPALADSVRYRRKRAGHLQSKGRFLAAQ
ECCCHHHCCHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHCCHHHCCHHHHHH
LLAMLEGDLWLENARAANAAAQAIVAEASERLLHPVEANEVFMRLTPPEREALREQGYHF
HHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHCCCEE
YDWGENAARLVASWDSDQEAARALGQAIASL
EECCCCHHHEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]